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Dalane W. Kitzman, M.D.Wake Forest School of Medicine

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Dalane W. Kitzman, M.D.

Professor,

Office of Research

Clinical Interests

Heart Failure, Cardiac Imaging, Stress Testing, Diastolic Dysfunction, Cardiology (clinical), Echocardiography, Geriatric Medicine and Assessment

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Education & Training

  • B.A., Johns Hopkins University, 1981
  • M.D., Johns Hopkins University School of Medicine, 1984
  • Internship, Internal Medicine, Mayo Graduate School, 1985
  • Residency, Internal Medicine, Mayo Graduate School, 1987
  • Fellowship, Duke University Hospital, 1990

Board Certifications

  • American Board of Internal Medicine, Cardiovascular Disease
  • American Board of Internal Medicine, Internal Medicine

Memberships

  • Am Assn Of Clinical Anatomists
  • American College of Cardiology
  • Am Coll Of Physicians
  • Am Medical Assn
  • Am Soc Of Echocardiography
  • Am Soc Of Internal Medicine
  • Albemarle County Medical Socie
  • Forsyth Prepared Childbirth As

NPI Number

  • 1396720678
Dalane W. Kitzman, M.D.

Doctor Rating

No Rating Available
Why No Ratings?

Dalane W. Kitzman, M.D.

Professor, Cardiology
Gerontology and Geriatric Medicine
Office of Research

Research Interests

Heart Failure; Stroke Volume; Exercise Tolerance; Oxygen Consumption; Ventricular Function, Left
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Contact Information

Request An Appointment

Academic: 336-716-3274 | Department: 336-716-3274

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Recent Publications

Association between 6-minute walk test distance and objective variables of functional capacity after exercise training in elderly heart failure patients with preserved ejection fraction: a randomized exercise trial. Maldonado-Martin S, Brubaker PH, Eggebeen J, Stewart KP, Kitzman DW.. Arch Phys Med Rehabil. 2017;98(3):600-603.

Heart failure stages among older adults in the community: the Atherosclerosis Risk in Communities study. Shah AM, Claggett B, Loehr LR, Chang PP, Matsushita K, Kitzman D, Konety SH, Kucharska-Newton A, Sueta CA, Mosley TH Jr, Wright JD, Coresh J, Heiss G, Folsom AR, Solomon SD.. Circulation. 2017;135(3):224-240.

Contemporary assessment of left ventricular diastolic function in older adults: the Atherosclerosis Risk in Communities study. Shah AM, Claggett B, Kitzman D, Biering-Sorensen T, Jensen JS, Cheng S, Matsushita K, Konety SH, Folsom AR, Mosley TH Jr, Wright J, Heiss G, Solomon SD.. Circulation. 2017;135(5):426-439.

Race-related differences in left ventricular structural and functional remodeling in response to increased afterload: the ARIC study. Fernandes-Silva MM, Shah AM, Hegde S, Goncalves A, Claggett B, Cheng S, Nadruz W, Kitzman DW, Konety SH, Matsushita K, Mosley T, Lam CS, Borlaug BA, Solomon SD.. JACC Heart Fail. 2017;5(3):157-165.

Understanding the journey. Kitzman DW.. J Am Geriatr Soc. 2017;65(2):443.

Age- and sex-related influences on left ventricular mechanics in elderly individuals free of prevalent heart failure: the ARIC study (Atherosclerosis Risk in Communities). Hung CL, Goncalves A, Shah AM, Cheng S, Kitzman D, Solomon SD.. Circ Cardiovasc Imaging. 2017;10(1):e004510.

Cellular basis of angiotensin-(1-7)-induced augmentation of left ventricular functional performance in heart failure. Zhang X, Cheng HJ, Zhou P, Kitzman DW, Ferrario CM, Li WM, Cheng CP.. Int J Cardiol. 2017;236():405-412.

Effect of intensive blood pressure control on gait speed and mobility limitation in adults 75 years or older: a randomized clinical trial. Odden MC, Peralta CA, Berlowitz DR, Johnson KC, Whittle J, Kitzman DW, Beddhu S, Nord JW, Papademetriou V, Williamson JD, Pajewski NM.. JAMA Intern Med. 2017;177(4):500-507.

Young dads and old men. Kitzman DW.. J Am Geriatr Soc. 2017;():.

Unraveling the relationship between aging and heart failure with preserved ejection fraction: the importance of exercise and normative reference standards [editorial comment]. Kitzman DW, O'Neill TJ IV, Brubaker PH.. JACC Heart Fail. 2017;():.

Rehabilitation therapy in older acute heart failure patients (REHAB-HF) trial: design and rationale. Reeves GR, Whellan DJ, Duncan P, O'Connor CM, Pastva AM, Eggebeen JD, Hewston LA, Morgan TM, Reed SD, Rejeski WJ, Mentz RJ, Rosenberg PB, Kitzman DW.. Am Heart J. 2017;185():130-139.

A novel rehabilitation intervention for older patients with acute decompensated heart failure: the REHAB-HF pilot study. Reeves GR, Whellan DJ, O'Connor CM, Duncan P, Eggebeen JD, Morgan TM, Hewston LA, Pastva A, Patel MJ, Kitzman DW.. JACC Heart Fail. 2017;():.

Management of heart failure with preserved ejection fraction: current challenges and future directions. Upadhya B, Kitzman DW.. Am J Cardiovasc Drugs. 2017;():.

Prediction of the effect of atrasentan on renal and heart failure outcomes based on short-term changes in multiple risk markers. Schievink B, de Zeeuw D, Smink PA, Andress D, Brennan JJ, Coll B, Correa-Rotter R, Hou FF, Kohan D, Kitzman DW, Makino H, Parving HH, Perkovic V, Remuzzi G, Tobe S, Toto R, Hoekman J, Lambers Heerspink HJ.. Eur J Prev Cardiol. 2016;23(7):758-768.

Response to exercise training and outcomes in patients with heart failure and diabetes mellitus: insights from HF-ACTION trial. Banks AZ, Mentz RJ, Stebbins A, PhD CR, Schulte PJ, Fleg JL, Cooper LS, Leifer ES, Badenhop DT, Keteyian SJ, Pina IL, Kitzman DW, Fiuzat M, Whellan DJ, Kraus WE, O'Connor CM.. J Card Fail. 2016;22(7):485-491.

Overexpression myocardial inducible nitric oxide synthase exacerbates cardiac dysfunction and beta-adrenergic desensitization in experimental hypothyroidism. Shao Q, Cheng HJ, Callahan MF, Kitzman DW, Li WM, Cheng CP.. Int J Cardiol. 2016;204():229-241.

Vascular dysfunction in heart failure with preserved ejection fraction [editorial]. Kitzman DW, Haykowsky MJ.. J Card Fail. 2016;22(1):12-16.

Effect of caloric restriction or aerobic exercise training on peak oxygen consumption and quality of life in obese older patients with heart failure with preserved ejection fraction: a randomized clinical trial. Kitzman DW, Brubaker P, Morgan T, Haykowsky M, Hundley G [sic] [Hundley WG], Kraus WE, Eggebeen J, Nicklas BJ.. JAMA. 2016;315(1):36-46.

Prospective association of GLUL rs10911021 with cardiovascular morbidity and mortality among individuals with type 2 diabetes: the Look AHEAD Study. Huggins GS, Berkowitz RI, Blackburn GL, Bray GA, Cheskin L, Clark JM, Coday M, Espeland MA, Evans M, Foreyt JP, Glasser S, Greenway FL, Gregg EW, Hanson RL, Hazuda HP, Hill JO, Horton ES, Jakicic JM, Jeffery RW, Johnson KC, Kahn SE, Kitzman DW,.. Diabetes. 2016;65(1):297-302.

Patterns and correlates of baseline thiazide-type diuretic prescription in the systolic blood pressure intervention trial. Chang TI, Evans G, Cheung AK, Cushman WC, Diamond MJ, Dwyer JP, Huan Y, Kitzman D, Kostis JB, Oparil S, Rastogi A, Roumie CL, Sahay R, Stafford RS, Taylor AA, Wright JT Jr, Chertow GM.. Hypertension. 2016;67(3):550-555.

One week of daily dosing with beetroot juice improves submaximal endurance and blood pressure in older patients with heart failure and preserved ejection fraction. Eggebeen J, Kim-Shapiro DB, Haykowsky M, Morgan TM, Basu S, Brubaker P, Rejeski J, Kitzman DW.. JACC Heart Fail. 2016;4(6):428-437.

Left atrial structure and function across the spectrum of cardiovascular risk in the elderly: the Atherosclerosis Risk in Communities study. Goncalves A, Hung CL, Claggett B, Nochioka K, Cheng S, Kitzman DW, Shah AM, Solomon SD.. Circ Cardiovasc Imaging. 2016;9(2):e004010.

Precious memory. Kitzman DW.. J Am Geriatr Soc. 2016;64(3):640.

Burden of systolic and diastolic left ventricular dysfunction among Hispanics in the United States: insights from the Echocardiographic Study of Latinos. Mehta H, Armstrong A, Swett K, Shah SJ, Allison MA, Hurwitz B, Bangdiwala S, Dadhania R, Kitzman DW, Arguelles W, Lima J, Youngblood M, Schneiderman N, Daviglus ML, Spevack D, Talavera GA, Raisinghani A, Kaplan R, Rodriguez CJ.. Circ Heart Fail. 2016;9(4):e002733.

Skeletal muscle mitochondrial content, oxidative capacity, and Mfn2 expression are reduced in older patients with heart failure and preserved ejection fraction and are related to exercise intolerance. Molina AJ, Bharadwaj MS, Van Horn C, Nicklas BJ, Lyles MF, Eggebeen J, Haykowsky MJ, Brubaker PH, Kitzman DW.. JACC Heart Fail. 2016;4(8):636-645.

Comparison of frequency of frailty and severely impaired physical function in patients greater than or equal to 60 years hospitalized with acute decompensated heart failure versus chronic stable heart failure with reduced and preserved. Reeves GR, Whellan DJ, Patel MJ, O'Connor CM, Duncan P, Eggebeen JD, Morgan TM, Hewston LA, Pastva AM, Kitzman DW.. Am J Cardiol. 2016;117(12):1953-1958.

Intensive vs standard blood pressure control and cardiovascular disease outcomes in adults aged greater than or equal to 75 years: a randomized clinical trial. Williamson JD, Supiano MA, Applegate WB, Berlowitz DR, Campbell RC, Chertow GM, Fine LJ, Haley WE, Hawfield AT, Ix JH, Kitzman DW, Kostis JB, Krousel-Wood MA, Launer LJ, Oparil S, Rodriguez CJ, Roumie CL, Shorr RI, Sink KM, Wadley VG,.. JAMA. 2016;315(24):2673-2682.

Race and sex differences in the incidence and prognostic significance of silent myocardial infarction in the Atherosclerosis Risk in Communities (ARIC) study. Zhang ZM, Rautaharju PM, Prineas RJ, Rodriguez CJ, Loehr L, Rosamond WD, Kitzman D, Couper D, Soliman EZ.. Circulation. 2016;133(22):2141-2148.

The HFpEF obesity phenotype: the elephant in the room [editorial comment]. Kitzman DW, Shah SJ.. J Am Coll Cardiol. 2016;68(2):200-203.

Phenotype-specific treatment of heart failure with preserved ejection fraction: a multiorgan roadmap. Shah SJ, Kitzman DW, Borlaug BA, van Heerebeek L, Zile MR, Kass DA, Paulus WJ.. Circulation. 2016;134(1):73-90.

Knowledge gaps in cardiovascular care of the older adult population: a scientific statement from the American Heart Association, American College of Cardiology, and American Geriatrics Society. Rich MW, Chyun DA, Skolnick AH, Alexander KP, Forman DE, Kitzman DW, Maurer MS, McClurken JB, Resnick BM, Shen WK, Tirschwell DL.. J Am Coll Cardiol. 2016;67(20):2419-2440.

Impaired alveolar capillary membrane diffusion: a recently recognized contributor to exertional dyspnea in heart failure with preserved ejection fraction [editorial comment]. Kitzman DW, Guazzi M.. JACC Heart Fail. 2016;4(6):499-501.

Transcatheter interatrial shunt device for the treatment of heart failure: rationale and design of the randomized trial to REDUCE elevated left atrial pressure in heart failure (REDUCE LAP-HF I). Feldman T, Komtebedde J, Burkhoff D, Massaro J, Maurer MS, Leon MB, Kaye D, Silvestry FE, Cleland JG, Kitzman D, Kubo SH, Van Veldhuisen DJ, Kleber F, Trochu JN, Auricchio A, Gustafsson F, Hasenful G, Ponikowski P, Filippatos G, Mauri L, Shah SJ.. Circ Heart Fail. 2016;9(7):e003025.

Prognostic importance of self-reported dyspnea for cardiovascular outcomes in persons without prevalent cardiovascular or pulmonary disease: the Atherosclerosis Risk in Communities Study [abstract]. Santos M, Kitzman D, Matsushita K, Loehr L, Sueta C, Shah A.. J Am Coll Cardiol. 2016;67(13 Suppl):1341.

Diet and exercise for obese patients with heart failure [reply to letter]. Kitzman DW, Haykowsky MJ, Kraus W.. JAMA. 2016;315(23):2619-2620.

Statins and exercise training response in heart failure patients: insights from HF-ACTION. Kelly JP, Dunning A, Schulte PJ, Fiuzat M, Leifer ES, Fleg JL, Cooper LS, Keteyian SJ, Kitzman DW, Pina IL, Kraus WE, Whellan DJ, O'Connor CM, Mentz RJ.. JACC Heart Fail. 2016;4(8):617-624.

Heart failure: exercise based cardiac rehabilitation: who, when and how intense?. Haykowsky MJ, Daniel K, Bhella P, Sarma S, Kitzman D.. Can J Cardiol. 2016;32(10 Suppl 2):S382-S387.

Association of weight and body composition on cardiac structure and function in the ARIC study (Atherosclerosis Risk in Communities). Bello NA, Cheng S, Claggett B, Shah AM, Ndumele CE, Roca GQ, Santos AB, Gupta D, Vardeny O, Aguilar D, Folsom AR, Butler KR, Kitzman DW, Coresh J, Solomon SD.. Circ Heart Fail. 2016;9(8):e002978.

Exercise training in patients with chronic heart failure and atrial fibrillation: results from the HF-ACTION Trial [abstract]. Luo N, Merrill P, Whellan DJ, Pina IL, Fiuzat M, Kraus WE, Kitzman DW, Keteyian SJ, O'Connor CM, Mentz RJ.. J Card Fail. 2016;22(8 Suppl):S71.

Smoking and cardiac structure and function in the elderly: the ARIC study (Atherosclerosis Risk in Communities). Nadruz W Jr, Claggett B, Goncalves A, Querejeta-Roca G, Fernandes-Silva MM, Shah AM, Cheng S, Tanaka H, Heiss G, Kitzman DW, Solomon SD.. Circ Cardiovasc Imaging. 2016;9(9):e004950.

Knowledge gaps in cardiovascular care of older adults: a scientific statement from the American Heart Association, American College of Cardiology, and American Geriatrics Society: executive summary. Rich MW, Chyun DA, Skolnick AH, Alexander KP, Forman DE, Kitzman DW, Maurer MS, McClurken JB, Resnick BM, Shen WK, Tirschwell DL.. J Am Geriatr Soc. 2016;64(11):2185-2192.

Differential responses of post-exercise recovery of leg blood flow and oxygen uptake kinetics in HFpEF versus HFrEF. Thompson RB, Pagano JJ, Mathewson KW, Paterson I, Dyck JR, Kitzman DW, Haykowsky MJ.. PLoS One. 2016;11(10):e0163513.

Heart failure in older adults: embracing complexity. Pirmohamed A, Kitzman DW, Maurer MS.. J Geriatr Cardiol. 2016;13(1):8-14.

Cardiovascular dysfunction and frailty among older adults in the community: the ARIC Study. Nadruz W Jr, Kitzman D, Windham BG, Kucharska-Newton A, Butler K, Palta P, Griswold ME, Wagenknecht LE, Heiss G, Solomon SD, Skali H, Shah AM.. J Gerontol A Biol Sci Med Sci. 2016;():.

Prognostic importance of dyspnea for cardiovascular outcomes and mortality in persons without prevalent cardiopulmonary disease: the Atherosclerosis Risk in Communities Study. Santos M, Kitzman DW, Matsushita K, Loehr L, Sueta CA, Shah AM.. PLoS One. 2016;11(10):e0165111.

New concepts in an old disease: exercise intolerance in moderate mitral stenosis [editorial comment]. Kitzman DW, Upadhya B, Zhao D.. JACC Cardiovasc Imaging. 2016;():.

Prognostic utility of GDF-15 in chronic heart failure: insights from the HF-ACTION Study [abstract]. Sharma A, Stevens S, Lucas J, Fiuzat M, Adams KF, Whellan DJ, Donahue MP, Kitzman DW, Pina IL, Zannad F, Kraus WE, O'Connor CM, Felker GM.. Eur Heart J. 2016;37(Suppl 1):441.

Four-year physical activity levels among intervention participants with type 2 diabetes. Unick JL, Gaussoin SA, Hill JO, Jakicic JM, Bond DS, Hellgren M, Johnson KC, Peters AL, Coday M, Kitzman DW, Bossart S, Wing RR.. Med Sci Sports Exerc. 2016;48(12):2437-2445.

Reversal of aging-induced upregulation of cardiac inducible nitric oxide synthase and beta-adrenergic desensitization in mice deficient in beta3-adrenoreceptor [abstract]. Cheng H-J, Zhou P, Li T, Zhang Z, Kitzman DW, Gorban L, Cheng C-P.. Circulation. 2016;134(Suppl 1):A14375.

Increased cardiovascular stiffness and impaired age-related functional status. Andersen MM, Kritchevsky SB, Morgan TM, Hire DG, Vasu S, Brinkley TE, Kitzman DW, Hamilton CA, Soots S, Hundley WG.. J Gerontol A Biol Sci Med Sci. 2015;70(5):545-553.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Professor, Cardiology

Clinical Interests

Heart Failure, Cardiac Imaging, Stress Testing, Diastolic Dysfunction, Cardiology (clinical), Echocardiography, Geriatric Medicine and Assessment
Dalane W. Kitzman, M.D.

Dalane W. Kitzman, M.D.

Professor, Cardiology
Gerontology and Geriatric Medicine
Office of Research

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