Nancy D. Kock, D.V.M., Ph.D.Wake Forest School of Medicine

Nancy D. Kock, D.V.M., Ph.D.


Contact Information

Academic: 336-713-7389 | Department: 336-713-7389


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Education & Training

  • B.S., University of California-Irvine, 1971
  • M.S., University of the Pacific, 1977
  • D.V.M., University of California-Davis, 1981
  • Ph.D., University of California-Davis, 1995
  • Fellowship, Animal Behavioral, University of the Pacific, 1977
  • Residency, Comparative Pathology, University of California-Davis, 1983


  • Am Veterinary Medical Assn
Nancy D. Kock, D.V.M., Ph.D.

Nancy D. Kock, D.V.M., Ph.D.

Professor, Pathology-Comparative Medicine

Contact Information

Academic: 336-713-7389 | Department: 336-713-7389


Related Links

Recent Publications

Pandya DN, Hantgan R, Budzevich MM, Kock ND, Morse DL, Batista I, Mintz A, Li KC, Wadas TJ. Preliminary therapy evaluation of (225)Ac-DOTA-c(RGDyK) demonstrates that cerenkov radiation derived from (225)Ac daughter decay can be detected by optical imaging for in vivo tumor visualization. Theranostics. 2016;6(5):698-709.

Holbrook BC, Hayward SL, Blevins LK, Kock N, Aycock T, Parks GD, Alexander-Miller MA. Nonhuman primate infants have an impaired respiratory but not systemic IgG antibody response following influenza virus infection. Virology. 2015;476():124-133.

Kim JR, Holbrook BC, Hayward SL, Blevins LK, Jorgensen MJ, Kock ND, De Paris K, D'Agostino R Jr, Aycock ST, Mizel SB, Parks GD, Alexander-Miller MA. Inclusion of flagellin during vaccination against influenza enhances recall responses in nonhuman primate neonates. J Virol. 2015;89(14):7291-7303.

Suburu J, Shi L, Wu J, Wang S, Samuel M, Thomas MJ, Kock ND, Yang G, Kridel S, Chen YQ. Fatty acid synthase is required for mammary gland development and milk production during lactation. Am J Physiol Endocrinol Metab. 2014;306(10):E1132-1143.

Ganguly T, Johnson JB, Kock ND, Parks GD, Deora R. The Bordetella pertussis Bps polysaccharide enhances lung colonization by conferring protection from complement-mediated killing. Cell Microbiol. 2014;16(7):1105-1118.

Lane EP, Clauss M, Kock ND, Hill FWG, Majok AA, Kotze A, Codron D. Body condition and ruminal morphology responses of free-ranging impala (Aepyceros melampus) to changes in diet. Eur J Wildl Res. 2014;60(4):599-612.

Miller MS, Moore JE, Walb MC, Kock ND, Attia A, Isom S, McBride JE, Munley MT. Chemoprevention by N-acetylcysteine of low-dose CT-induced murine lung tumorigenesis. Carcinogenesis. 2013;34(2):319-324.

Eckman DM, Stacey RB, Rowe R, D'Agostino R Jr, Kock ND, Sane DC, Torti FM, Yeboah J, Workman S, Lane KS, Hundley WG. Weekly doxorubicin increases coronary arteriolar wall and adventitial thickness. PLoS One. 2013;8(2):e57554.

McDaniel AL, Alger HM, Sawyer JK, Kelley KL, Kock ND, Brown JM, Temel RE, Rudel LL. Phytosterol feeding causes toxicity in ABCG5/G8 knockout mice. Am J Pathol. 2013;182(4):1131-1138.

Lan T, Rao A, Haywood J, Kock ND, Dawson PA. Mouse organic solute transporter alpha deficiency alters FGF15 expression and bile acid metabolism. J Hepatol. 2012;57(2):359-365.

Pang B, Hong W, Kock ND, Swords WE. Dps promotes survival of nontypeable Haemophilus influenzae in biofilm communities in vitro and resistance to clearance in vivo. Front Cell Infect Microbiol. 2012;2():58.

Stacey RB, Kock ND, D'Agostino RB Jr, Torti FM, Eckman DM, Sane DC, Workman S, Lane KS, Hundley WG. Doxorubicin associated changes in coronary artery histology [abstract]. J Am Coll Cardiol. 2011;57(14 Suppl 1):E1591.

Arnold AC, Shaltout HA, Gilliam-Davis S, Kock ND, Diz DI. Autonomic control of the heart is altered in Sprague-Dawley rats with spontaneous hydronephrosis. Am J Physiol Heart Circ Physiol. 2011;300(6):H2206-2213.

Burke AR, Singh RN, Carroll DL, Owen JD, Kock ND, D'Agostino R Jr, Torti FM, Torti SV. Determinants of the thrombogenic potential of multiwalled carbon nanotubes. Biomaterials. 2011;32(26):5970-5978.

Byrd MS, Pang B, Hong W, Waligora EA, Juneau RA, Armbruster CE, Weimer KED, Murrah K, Lu H, Sprinkle A, Kock ND, Swords WE, et al. Direct evaluation of Pseudomonas aeruginosa biofilm mediators in a chronic infection model. Infect Immun. 2011;79(8):3087-3095.

Clark KM, Johnson JB, Kock ND, Mizel SB, Parks GD. Parainfluenza virus 5-based vaccine vectors expressing vaccinia virus (VACV) antigens provide long-term protection in mice from lethal intranasal VACV challenge. Virology. 2011;419(2):97-106.

Munley MT, Moore JE, Walb MC, Isom SP, Olson JD, Zora JG, Kock ND, Wheeler KT, Miller MS. Cancer-prone mice expressing the Ki-rasG12C gene show increased lung carcinogenesis after CT screening exposures. Radiat Res. 2011;176(6):842-848.

Yang Q, Kock ND. Intestinal adaptation following massive ileocecal resection in 20-day-old weanling rats. J Pediatr Gastroenterol Nutr. 2010;50(1):16-21.

Sukumar N, Sloan GP, Conover MS, Love CF, Mattoo S, Kock ND, Deora R. Cross-species protection mediated by a Bordetella bronchiseptica strain lacking antigenic homologs present in acellular pertussis vaccines. Infect Immun. 2010;78(5):2008-2016.

Yang Q, Kock ND. Effects of dietary fish oil on intestinal adaptation in 20-day-old weanling rats after massive ileocecal resection. Pediatr Res. 2010;68(3):183-187.

Neal RE II, Singh R, Hatcher HC, Kock ND, Torti SV, Davalos RV. Treatment of breast cancer through the application of irreversible electroporation using a novel minimally invasive single needle electrode. Breast Cancer Res Treat. 2010;123(1):295-301.

Lightfoot JC, D'Agostino RB Jr, Hamilton CA, Jordan J, Torti FM, Kock ND, Jordan J, Workman S, Hundley WG. Novel approach to early detection of doxorubicin cardiotoxicity by gadolinium-enhanced cardiovascular magnetic resonance imaging in an experimental model. Circ Cardiovasc Imaging. 2010;3(5):550-558.

Miller MS, Moore JE, Olson J, Kock ND, Zora JG, Wheeler K, Munley MT. Low-dose CT irradiation increases lung tumorigenesis in a Ki-ras driven mouse model: results from a pilot study [abstract]. J Thorac Oncol. 2010;5(6 Suppl 3):S230.

Appt SE, Clarkson TB, Hoyer PB, Kock ND, Goode AK, May MC, Persyn JT, Ethun KF, Chen H, Kaplan JR, et al. Experimental induction of reduced ovarian reserve in a nonhuman primate model (Macaca fascicularis). Comp Med. 2010;60(5):380-388.

Sukumar N, Love CF, Conover MS, Kock ND, Dubey P, Deora R. Active and passive immunization with Bordetella colonization factor A protects mice against respiratory challenge with Bordetella bronchiseptica. Infect Immun. 2009;77(2):885-895.

Jiao Y, Wilkinson J IV, Di X, Wang W, Hatcher H, Kock ND, D'Agostino R Jr, Knovich MA, Torti FM, Torti SV. Curcumin, a cancer chemopreventive and chemotherapeutic agent, is a biologically active iron chelator. Blood. 2009;113(2):462-469.

Muhammad FS, Goode AK, Kock ND, Arifin EA, Cline JM, Adams MR, Hoyer PB, Christian PJ, Isom S, Kaplan JR, Appt SE. Effects of 4-vinylcyclohexene diepoxide on peripubertal and adult Sprague-Dawley rats: ovarian, clinical, and pathologic outcomes. Comp Med. 2009;59(1):46-59.

Weimer ET, Lu H, Kock ND, Wozniak DJ, Mizel SB. A fusion protein vaccine containing OprF epitope 8, OprI, and type A and B flagellins promotes enhanced clearance of nonmucoid Pseudomonas aeruginosa. Infect Immun. 2009;77(6):2356-2366.

Dance-Barnes ST, Kock ND, Moore JE, Lin EY, Mosley LJ, D'Agostino RB Jr, McCoy TP, Townsend AJ, Miller MS. Lung tumor promotion by curcumin. Carcinogenesis. 2009;30(6):1016-1023.

Armbruster CE, Hong W, Pang B, Dew KE, Juneau RA, Byrd MS, Love CF, Kock ND, Swords WE. LuxS promotes biofilm maturation and persistence of nontypeable haemophilus influenzae in vivo via modulation of lipooligosaccharides on the bacterial surface. Infect Immun. 2009;77(9):4081-4091.

Mohanan S, Wagner JD, Kock ND, Kavanagh K, Cline JM. Hepatic Mallory-Denk body formation in a streptozotocin-treated vervet monkey (Chlorocebus aethiops) [abstract]. Toxicol Pathol. 2009;37(1):135-136.

Burke A, Singh R, Kraft RA, Levi-Polyachenko N, Hatcher HC, D'Agostino R Jr, Kock ND, Carroll DL, Akman S, Torti FM, Torti SV, et al. Long-term survival following a single treatment of kidney tumors with multiwalled carbon nanotubes and near-infrared radiation. Proc Natl Acad Sci U S A. 2009;106(31):12897-902.

Bates JT, Honko AN, Graff AH, Kock ND, Mizel SB. Mucosal adjuvant activity of flagellin in aged mice. Mech Ageing Dev. 2008;129(5):271-281.

Pang B, Winn D, Johnson R, Hong W, West-Barnette S, Kock N, Swords WE. Lipooligosaccharides containing phosphorylcholine delay pulmonary clearance of nontypeable Haemophilus influenzae. Infect Immun. 2008;76(5):2037-2043.

Dance ST, Kock ND, Moore JE, Agostino [sic] RB Jr [D'Agostino RB Jr], Mosley LJ, Miller MS. Chemoprevention of murine lung tumor progression by sulindac [abstract]. Toxicol Sci. 2008;102(S-1 [Toxicologist]):179.

Miller MS, Dance ST, Kock ND, Moore JE, D'Agostino RB Jr, Mosley LJ, Townsend AJ. Lung tumor promotion by curcumin [abstract]. Toxicol Sci. 2008;102(S-1 [Toxicologist]):23.

Capraro GA, Johnson JB, Kock ND, Parks GD. Virus growth and antibody responses following respiratory tract infection of ferrets and mice with WT and P/V mutants of the paramyxovirus Simian Virus 5. Virology. 2008;376(2):416-428.

Sikoski P, Trybus J, Cline JM, Muhammad FS, Eckhoff A, Tan J, Lockard M, Jolley T, Britt S, Kock ND. Cystic mammary adenocarcinoma associated with a prolactin-secreting pituitary adenoma in a New Zealand white rabbit (Oryctolagus cuniculus). Comp Med. 2008;58(3):297-300.

Dance-Barnes ST, Kock ND, Floyd HS, Moore JE, Mosley LJ, D'Agostino RB Jr, Pettenati MJ, Miller MS. Effects of mutant human Ki-rasG12C gene dosage on murine lung tumorigenesis and signaling to its downstream effectors. Toxicol Appl Pharmacol. 2008;231(1):77-84.

Ahmed M, Marino TR, Puckett S, Kock ND, Lyles DS. Immune response in the absence of neurovirulence in mice infected with m protein mutant vesicular stomatitis virus. J Virol. 2008;82(18):9273-9277.

Pang B, Hong W, West-Barnette SL, Kock ND, Swords WE. Diminished ICAM-1 expression and impaired pulmonary clearance of nontypeable Haemophilus influenzae in a mouse model of chronic obstructive pulmonary disease/emphysema. Infect Immun. 2008;76(11):4959-4967.

Scott LM, Xu X, Veenstra TD, Tooze JA, Wood CE, Register TC, Kock ND, Cline JM. Past oral contraceptive use and current dietary soy isoflavones influence estrogen metabolism in postmenopausal monkeys (Macaca fascicularis). Cancer Epidemiol Biomarkers Prev. 2008;17(10):2594-2602.

Hatcher HC, Kock ND, Pettus J, Richard JR, Torti SV. Cytoprotective effect of ferritin following oxidative stress in renal ischemia-reperfusion injury [abstract]. Free Radic Biol Med. 2008;45(Suppl 1):S83.

Lally BE, Geiger GA, Kridel S, Arcury-Quandt AE, Robbins ME, Kock ND, Wheeler K, Peddi P, Georgakilas A, Koumenis C, et al. Identification and biological evaluation of a novel and potent small molecule radiation sensitizer via an unbiased screen of a chemical library. Cancer Res. 2007;67(18):8791-8799.

Muhammad FS, Perry D, Phifer B, Richardson D, Kock N. Spleen morphology and morphometry in wild-caught cynomolgus macaques (M-fascicularis): a comparison between short- and long-term captivity [abstract]. J Am Assoc Lab Anim Sci. 2007;46(4):136-137.

Sikoski P, Trybus J, Kock ND, Muhammad F, Eckhoff A, Tan J, Lockard M, Jolley T, Britt S, Cline J. Cystic mammary adenocarcinoma associated with a prolactin-secreting pituitary adenoma in a New Zealand white rabbit (Oryctolagus cuniculus) [abstract]. J Am Assoc Lab Anim Sci. 2007;46(4):105.

Nyamambi B, Ndlovu LR, Naik YS, Kock ND. Intestinal growth and function of broiler chicks fed sorghum based diets differing in condensed tannin levels. S Afr J Anim Sci. 2007;37(3):202-214.

Floyd HS, Jennings-Gee JE, Kock ND, Miller MS. Genetic and epigenetic alterations in lung tumors from bitransgenic Ki-rasG12C expressing mice. Mol Carcinog. 2006;45(7):506-517.

Remick AK, Wood CE, Cann JA, Gee MK, Feiste EA, Kock ND, Cline JM. Histologic and immunohistochemical characterization of spontaneous pituitary adenomas in fourteen cynomolgus macaques (Macaca fascicularis). Vet Pathol. 2006;43(4):484-493.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Nancy D. Kock, D.V.M., Ph.D.

Nancy D. Kock, D.V.M., Ph.D.

Professor, Pathology-Comparative Medicine

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