Profile

Steven J. Kridel, Ph.D.

Steven J. Kridel, Ph.D.

Associate Professor, Cancer Biology
Comprehensive Cancer Center
Brain Tumor Center of Excellence
Urology
Contact Information
Office:
336-716-7299
Fax:
336-716-0255
Email: skridel@wakehealth.edu
Education & Training
  BScCal State University-Los Angeles1992
  PhDUniversity of California-Irvine1997
Steven J. Kridel, Ph.D.

Steven J. Kridel, Ph.D.

Associate Professor, Cancer Biology
Comprehensive Cancer Center
Brain Tumor Center of Excellence
Urology
Contact Information
Office:
336-716-7299
Fax:
336-716-0255
Email: skridel@wakehealth.edu
Research Interests
cancer/oncogenesis , metabolism , molecular biology/molecular me
Recent Publications
Debinski W, Garg S, Gibo DM, Kridel S, Pandya H. Isolation and characterization of interleukin 13 receptor alpha2-specific heptapeptides [abstract]. Neuro Oncol. 2009; 11(6):898.


Vavere AL, Kridel SJ, Wheeler FB, Lewis JS. 1-C-11-acetate as a PET radiopharmaceutical for imaging fatty acid synthase expression in prostate cancer. J Nucl Med. 2008; 49(2):327-334.


Fels DR, Ye J, Segan AT, Kridel SJ, Spiotto M, Olson M, Koong AC, Koumenis C. Preferential cytotoxicity of bortezomib toward hypoxic tumor cells via overactivation of endoplasmic reticulum stress pathways. Cancer Res. 2008; 68(22):9323-9330.


Little JL, Wheeler FB, Koumenis C, Kridel SJ. Disruption of crosstalk between the fatty acid synthesis and proteasome pathways enhances unfolded protein response signaling and cell death. Mol Cancer Ther. 2008; 7(12):3816-3824.


Little JL, Kridel SJ. Fatty acid synthase activity in tumor cells. Subcell Biochem. 2008; 49():169-194.


Little JL, Wheeler FB, Fels DR, Koumenis C, Kridel SJ. Inhibition of fatty acid synthase induces endoplasmic reticulum stress in tumor cells. Cancer Res. 2007; 67(3):1262-1269.


Pemble CW IV, Johnson LC, Kridel SJ, Lowther WT. Crystal structure of the thioesterase domain of human fatty acid synthase inhibited by Orlistat. Nat Struct Mol Biol. 2007; 14(8):704-709.


Lally BE, Geiger GA, Kridel S, Arcury-Quandt AE, Robbins ME, Kock ND, Wheeler K, Peddi P, Georgakilas A, Koumenis C, et al. Identification and biological evaluation of a novel and potent small molecule radiation sensitizer via an unbiased screen of a chemical library. Cancer Res. 2007; 67(18):8791-8799.


Kridel SJ, Lowther WT, Pemble CW IV. Fatty acid synthase inhibitors: new directions for oncology. Expert Opin Investig Drugs. 2007; 16(11):1817-1829.


Chen YQ, Edwards IJ, Kridel SJ, Thornburg T, Berquin IM. Dietary fat-gene interactions in cancer. Cancer Metastasis Rev. 2007; 26(3-4):535-551.


Zhao W, Kridel S, Thorburn A, Kooshki M, Little J, Hebbar S, Robbins M. Fatty acid synthase: a novel target for antiglioma therapy. Br J Cancer. 2006; 95(7):869-878.
All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Back To Top
Last Updated 12/31/2011
Loading...
Quick Reference
Request an Appointment
New Patients
336-716-WAKE
888-716-WAKE
Existing patients may contact the clinic directly.
Locate Faculty

e.g., "allergy," "diabetes"

US News Best Hospital AwardANCC Magnet Association AwardBest Doctors 2011-2012 AwardThe Joint Commission National Quality ApprovalConsumer Choice #1 Award 2011-2102US News Best Medical Schools 2011 Award
Loading...

Disclaimer: The information on this website is for general informational purposes only and SHOULD NOT be relied upon as a substitute for sound professional medical advice, evaluation or care from your physician or other qualified health care provider.