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Stephen Kritchevsky, Ph.D.Wake Forest School of Medicine

Stephen Kritchevsky, Ph.D.

Deputy Director,
Director,
Professor,

Ctr for Vaccines at Extremes

Contact Information

Academic: 336-713-8548 | Department: 336-713-8570

Media Medical Expert »

Education & Training

  • M.S.P.H., University of North Carolina School of Public Hlth, 1986
  • Ph.D., University of North Carolina-Chapel Hill, 1989

Memberships

  • Am Geriatrics Society
  • Am Heart Association
  • Gerontological Society Of Amer
Stephen Kritchevsky, Ph.D.

Stephen Kritchevsky, Ph.D.

Deputy Director, Translational Science Institute
Director, Sticht Center on Aging
Professor, Gerontology and Geriatric Medicine
Center on Diabetes, Obesity, and Metabolism
Ctr for Vaccines at Extremes

Research Interests

Aging; Body Composition; Aged; Obesity; Female
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Contact Information

Academic: 336-713-8548 | Department: 336-713-8570

Media Medical Expert »

Recent Publications

Sensorimotor peripheral nerve function and the longitudinal relationship with endurance walking in the Health, Aging and Body Composition study. Lange-Maia BS, Newman AB, Cauley JA, Boudreau RM, Jakicic JM, Caserotti P, Glynn NW, Harris TB, Kritchevsky SB, Schwartz AV, Satterfield S, Simonsick EM, Vinik AI, Zivkovic S, Strotmeyer ES.. Arch Phys Med Rehabil. 2016;97(1):45-52.

Depressive trajectories and risk of disability and mortality in older adults: longitudinal findings from the Health, Aging, and Body Composition study. Murphy RA, Hagaman AK, Reinders I, Steeves JA, Newman AB, Rubin SM, Satterfield S, Kritchevsky SB, Yaffe K, Ayonayon HN, Nagin DS, Simonsick EM, Penninx BW, Harris TB.. J Gerontol A Biol Sci Med Sci. 2016;71(2):228-235.

Association of hearing impairment with incident frailty and falls in older adults. Kamil RJ, Betz J, Powers BB, Pratt S, Kritchevsky S, Ayonayon HN, Harris TB, Helzner E, Deal JA, Martin K, Peterson M, Satterfield S, Simonsick EM, Lin FR.. J Aging Health. 2016;28(4):644-660.

Low plasma klotho concentrations and decline of knee strength in older adults. Semba RD, Ferrucci L, Sun K, Simonsick E, Turner R, Miljkovic I, Harris T, Schwartz AV, Asao K, Kritchevsky S, Newman AB.. J Gerontol A Biol Sci Med Sci. 2016;71(1):103-108.

Association of serum erythropoietin with cardiovascular events, kidney function decline, and mortality: the Health Aging and Body Composition Study. Garimella PS, Katz R, Patel KV, Kritchevsky SB, Parikh CR, Ix JH, Fried LF, Newman AB, Shlipak MG, Harris TB, Sarnak MJ.. Circ Heart Fail. 2016;9(1):e002124.

Vitamin K status and lower extremity function in older adults: the Health Aging and Body Composition Study. Shea MK, Loeser RF, Hsu FC, Booth SL, Nevitt M, Simonsick EM, Strotmeyer ES, Vermeer C, Kritchevsky SB.. J Gerontol A Biol Sci Med Sci. 2016;71(10):1348-1355.

Comparison of handgrip and leg extension strength in predicting slow gait speed in older adults. Fragala MS, Alley DE, Shardell MD, Harris TB, McLean RR, Kiel DP, Cawthon PM, Dam TT, Ferrucci L, Guralnik JM, Kritchevsky SB, Vassileva MT, Gudnason V, Eiriksdottir G, Koster A, Newman A, Siggeirsdottir K, Satterfield S, Studenski SA, Kenny AM.. J Am Geriatr Soc. 2016;64(1):144-150.

Diabetes, hyperglycemia, and the burden of functional disability among older adults in a community-based study. Godino JG, Appel LJ, Gross AL, Schrack JA, Parrinello CM, Kalyani RR, Windham BG, Pankow JS, Kritchevsky SB, Bandeen-Roche K, Selvin E.. J Diabetes. 2016;():.

Cost-effectiveness of the LIFE physical activity intervention for older adults at increased risk for mobility disability. Groessl EJ, Kaplan RM, Castro Sweet CM, Church T, Espeland MA, Gill TM, Glynn NW, King AC, Kritchevsky S, Manini T, McDermott MM, Reid KF, Rushing J, Pahor M.. J Gerontol A Biol Sci Med Sci. 2016;71(5):656-662.

Changes in bone mineral density over time by body mass index in the Health ABC Study. Lloyd JT, Alley DE, Hochberg MC, Waldstein SR, Harris TB, Kritchevsky SB, Schwartz AV, Strotmeyer ES, Womack C, Orwig DL.. Osteoporos Int. 2016;27(6):2109-2116.

Association between anthropometric measures and long-term survival in frail older women: observations from the Women's Health Initiative Study. Zaslavsky O, Rillamas-Sun E, LaCroix AZ, Woods NF, Tinker LF, Zisberg A, Shadmi E, Cochrane B, Edward BJ, Kritchevsky S, Stefanick ML, Vitolins MZ, Wactawski-Wende J, Zelber-Sagi S.. J Am Geriatr Soc. 2016;64(2):277-284.

Sertraline inhibits increases in body fat and carbohydrate dysregulation in adult female cynomolgus monkeys. Silverstein-Metzler MG, Shively CA, Clarkson TB [deceased], Appt SE, Carr JJ, Kritchevsky SB, Jones SR, Register TC.. Psychoneuroendocrinology. 2016;68():29-38.

A multidimensional risk score to predict all-cause hospitalization in community-dwelling older individuals with obstructive lung disease. Beijers RJ, van den Borst B, Newman AB, Yende S, Kritchevsky SB, Cassano PA, Bauer DC, Harris TB, Schols AM.. J Am Med Dir Assoc. 2016;17(6):508-513.

Effect of statin use on mobility disability and its prevention in at-risk older adults: the LIFE study. Henderson RM, Lovato L, Miller ME, Fielding RA, Church TS, Newman AB, Buford TW, Pahor M, McDermott MM, Stafford RS, Lee DS, Kritchevsky SB.. J Gerontol A Biol Sci Med Sci. 2016;():.

Self-reported mobility in older patients predicts early postoperative outcomes after elective noncardiac surgery. Kim S, Marsh AP, Rustowicz L, Roach C, Leng XI, Kritchevsky SB, Rejeski WJ, Groban L.. Anesthesiology. 2016;124(4):815-825.

Association of muscle mass, area, and strength with incident diabetes in older adults: the Health ABC Study. Larsen BA, Wassel CL, Kritchevsky SB, Strotmeyer ES, Criqui MH, Kanaya AM, Fried LF, Schwartz AV, Harris TB, Ix JH.. J Clin Endocrinol Metab. 2016;101(4):1847-1855.

Genome-wide association study for incident myocardial infarction and coronary heart disease in prospective cohort studies: the CHARGE consortium. Dehghan A, Bis JC, White CC, Smith AV, Morrison AC, Cupples LA, Trompet S, Chasman DI, Lumley T, Volker U, Buckley BM, Ding J, Jensen MK, Folsom AR, Kritchevsky SB, Girman CJ, Ford I, Dorr M, Salomaa V, Uitterlinden AG, Eiriksdottir G, Vasan RS,.. PLoS One. 2016;11(3):e0144997.

Hearing impairment and physical function and falls in the Atherosclerosis Risk in Communities Hearing Pilot Study [letter]. Deal JA, Richey Sharrett A, Bandeen-Roche K, Kritchevsky SB, Pompeii LA, Gwen Windham B, Lin FR.. J Am Geriatr Soc. 2016;64(4):906-908.

Atrial fibrillation and declining physical performance in older adults: the Health, Aging, and Body Composition Study. Magnani JW, Wang N, Benjamin EJ, Garcia ME, Bauer DC, Butler J, Ellinor PT, Kritchevsky S, Marcus GM, Newman A, Phillips CL, Sasai H, Satterfield S, Sullivan LM, Harris TB.. Circ Arrhythm Electrophysiol. 2016;9(5):e003525.

Discovery of genetic variation on chromosome 5q22 associated with mortality in heart failure. Smith JG, Felix JF, Morrison AC, Kalogeropoulos A, Trompet S, Wilk JB, Gidlof O, Wang X, Morley M, Mendelson M, Joehanes R, Ligthart S, Shan X, Bis JC, Wang YA, Sjogren M, Ngwa J, Brandimarto J, Stott DJ, Aguilar D, Rice KM, Sesso HD, Demissie S,.. PLoS Genet. 2016;12(5):e1006034.

Hospitalizations during a physical activity intervention in older adults at risk of mobility disability: analyses from the Lifestyle Interventions and Independence for Elders randomized clinical trial. Marsh AP, Applegate WB, Guralnik JM, Jack Rejeski W, Church TS, Fielding RA, Gill TM, King AC, Kritchevsky SB, Manini TM, McDermott MM, Newman AB, Stowe CL, Walkup MP, Pahor M, Miller ME.. J Am Geriatr Soc. 2016;64(5):933-943.

Metformin as a tool to target aging. Barzilai N, Crandall JP, Kritchevsky SB, Espeland MA.. Cell Metab. 2016;23(6):1060-1065.

GWAS analysis of handgrip and lower body strength in older adults in the CHARGE consortium. Matteini AM, Tanaka T, Karasik D, Atzmon G, Chou WC, Eicher JD, Johnson AD, Arnold AM, Callisaya ML, Davies G, Evans DS, Holtfreter B, Lohman K, Lunetta KL, Mangino M, Smith AV, Smith JA, Teumer A, Yu L, Arking DE, Buchman AS, Chibinik LB, De Jager PL,.. Aging Cell. 2016;15(5):792-800.

Effects of disease burden and functional adaptation on morbidity and mortality on older adults. Sanders JL, Arnold AM, Hirsch CH, Thielke SM, Kim D, Mukamal KJ, Kizer JR, Ix JH, Kaplan RC, Kritchevsky SB, Newman AB.. J Am Geriatr Soc. 2016;64(6):1242-1249.

Statin use and all-cancer survival: prospective results from the Women's Health Initiative. Wang A, Aragaki AK, Tang JY, Kurian AW, Manson JE, Chlebowski RT, Simon M, Desai P, Wassertheil-Smoller S, Liu S, Kritchevsky S, Wakelee HA, Stefanick ML.. Br J Cancer. 2016;115(1):129-135.

Sarcopenia definition parameters and incident disability [abstract]. Schaap LA, Simonsick EM, Newman AB, Schwartz AV, Caserotti P, Kritchevsky SB, Goodpaster BH, Harris TB, Visser M.. Osteoporos Int. 2016;27(Suppl 1):S53.

Commentary: connections across life stages and disease risk: commentary on a study early in the life-course of life-course epidemiology. Kritchevsky SB.. Int J Epidemiol. 2016;():.

Operationalizing frailty in the Atherosclerosis Risk in Communities Study cohort. Kucharska-Newton AM, Palta P, Burgard S, Griswold ME, Lund JL, Capistrant BD, Kritchevsky SB, Bandeen-Roche K, Windham BG.. J Gerontol A Biol Sci Med Sci. 2016;():.

The decline in physical performance and onset of sarcopenia is associated with the development of urinary incontinence in older community dwelling women [abstract]. Parker-Autry C, Houston D, Rushing J, Richter H, Subak L, Kanaya A, Kritchevsky S.. Neurourol Urodyn. 2016;35(Suppl 4):S251-S252.

Cardiovascular events in a physical activity intervention compared with a successful aging intervention: the LIFE study randomized trial. Newman AB, Dodson JA, Church TS, Buford TW, Fielding RA, Kritchevsky S, Beavers D, Pahor M, Stafford RS, Szady AD, Ambrosius WT, McDermott MM.. JAMA Cardiol. 2016;1(5):568-574.

Impact of moderate physical activity on the longitudinal trajectory of a cardiac specific biomarker of injury: results from a randomized pilot study of exercise intervention. deFilippi CR, de Lemos JA, Newman AB, Guralnik JM, Christenson RH, Pahor M, Church T, Espeland M, Krithevsky SB [sic] [Kritchevsky SB], Stafford R, Seliger SL.. Am Heart J. 2016;179():151-156.

Effects of physical activity intervention on physical and cognitive function in sedentary adults with and without diabetes. Espeland MA, Lipska K, Miller ME, Rushing J, Cohen RA, Verghese J, McDermott MM, King AC, Strotmeyer ES, Blair SN, Pahor M, Reid K, Demons J, Kritchevsky SB.. J Gerontol A Biol Sci Med Sci. 2016;():.

Body composition remodeling and mortality: the Health Aging and Body Composition Study. Santanasto AJ, Goodpaster BH, Kritchevsky SB, Miljkovic I, Satterfield S, Schwartz AV, Cummings SR, Boudreau RM, Harris TB, Newman AB.. J Gerontol A Biol Sci Med Sci. 2016;():.

Effects of longitudinal glucose exposure on cognitive and physical function: results from the Action for Health in Diabetes Movement and Memory study. Beavers KM, Leng I, Rapp SR, Miller ME, Houston DK, Marsh AP, Hire DG, Baker LD, Bray GA, Blackburn GL, Hergenroeder AL, Jakicic JM, Johnson KC, Korytkowski MT, Dorsten BV, Kritchevsky SB.. J Am Geriatr Soc. 2016;():.

Nutrition and healthy aging [editorial]. Kritchevsky SB.. J Gerontol A Biol Sci Med Sci. 2016;71(10):1303-1305.

Effect of intensive chemotherapy on physical, cognitive, and emotional health of older adults with acute myeloid leukemia. Klepin HD, Tooze JA, Pardee TS, Ellis LR, Berenzon D, Mihalko SL, Danhauer SC, Rao AV, Wildes TM, Williamson JD, Powell BL, Kritchevsky SB.. J Am Geriatr Soc. 2016;64(10):1988-1995.

Slow gait, white matter characteristics, and prior 10-year interleukin-6 levels in older adults. Nadkarni NK, Boudreau RM, Studenski SA, Lopez OL, Liu G, Kritchevsky S, Yaffe K, Newman AB, Rosano C.. Neurology. 2016;87(19):1993-1999.

Increased cardiovascular stiffness and impaired age-related functional status. Andersen MM, Kritchevsky SB, Morgan TM, Hire DG, Vasu S, Brinkley TE, Kitzman DW, Hamilton CA, Soots S, Hundley WG.. J Gerontol A Biol Sci Med Sci. 2015;70(5):545-553.

Association of hearing impairment and mortality in older adults. Genther DJ, Betz J, Pratt S, Kritchevsky SB, Martin KR, Harris TB, Helzner E, Satterfield S, Xue QL, Yaffe K, Simonsick EM, Lin FR.. J Gerontol A Biol Sci Med Sci. 2015;70(1):85-90.

Respirometric profiling of muscle mitochondria and blood cells are associated with differences in gait speed among community-dwelling older adults. Tyrrell DJ, Bharadwaj MS, Van Horn CG, Kritchevsky SB, Nicklas BJ, Molina AJ.. J Gerontol A Biol Sci Med Sci. 2015;70(11):1394-1399.

Vitamin D insufficiency and abnormal hemoglobin A1c in black and white older persons. Kositsawat J, Kuchel GA, Tooze JA, Houston DK, Cauley JA, Kritchevsky SB, Strotmeyer ES, Kanaya AM, Harris TB, Johnson KC, Barry LC.. J Gerontol A Biol Sci Med Sci. 2015;70(4):525-531.

Strength and function response to clinical interventions of older women categorized by weakness and low lean mass using classifications from the Foundation for the National Institute of Health Sarcopenia Project. Fragala MS, Dam TT, Barber V, Judge JO, Studenski SA, Cawthon PM, McLean RR, Harris TB, Ferrucci L, Guralnik JM, Kiel DP, Kritchevsky SB, Shardell MD, Vassileva MT, Kenny AM.. J Gerontol A Biol Sci Med Sci. 2015;70(2):202-209.

Multisystem physiologic impairments and changes in gait speed of older adults. Rosso AL, Sanders JL, Arnold AM, Boudreau RM, Hirsch CH, Carlson MC, Rosano C, Kritchevsky SB, Newman AB.. J Gerontol A Biol Sci Med Sci. 2015;70(3):319-324.

Sensory and motor peripheral nerve function and longitudinal changes in quadriceps strength. Ward RE, Boudreau RM, Caserotti P, Harris TB, Zivkovic S, Goodpaster BH, Satterfield S, Kritchevsky S, Schwartz AV, Vinik AI, Cauley JA, Newman AB, Strotmeyer ES.. J Gerontol A Biol Sci Med Sci. 2015;70(4):464-470.

A long-term intensive lifestyle intervention and physical function: The look AHEAD Movement and Memory study. Houston DK, Leng X, Bray GA, Hergenroeder AL, Hill JO, Jakicic JM, Johnson KC, Neiberg RH, Marsh AP, Rejeski WJ, Kritchevsky SB.. Obesity (Silver Spring). 2015;23(1):77-84.

Association of hearing impairment with declines in physical functioning and the risk of disability in older adults. Chen DS, Betz J, Yaffe K, Ayonayon HN, Kritchevsky S, Martin KR, Harris TB, Purchase-Helzner E, Satterfield S, Xue QL, Pratt S, Simonsick EM, Lin FR.. J Gerontol A Biol Sci Med Sci. 2015;70(5):654-661.

The association between vitamin K status and knee osteoarthritis features in older adults: the Health, Aging and Body Composition Study. Shea MK, Kritchevsky SB, Hsu FC, Nevitt M, Booth SL, Kwoh CK, McAlindon TE, Vermeer C, Drummen N, Harris TB, Womack C, Loeser RF.. Osteoarthritis Cartilage. 2015;23(3):370-378.

Declines in inflammation predict greater white matter microstructure in older adults. Bettcher BM, Yaffe K, Boudreau RM, Neuhaus J, Aizenstein H, Ding J, Kritchevsky SB, Launer LJ, Liu Y, Satterfield S, Rosano C.. Neurobiol Aging. 2015;36(2):948-954.

Dietary sodium content, mortality, and risk for cardiovascular events in older adults: the Health, Aging, and Body Composition (Health ABC) study. Kalogeropoulos AP, Georgiopoulou VV, Murphy RA, Newman AB, Bauer DC, Harris TB, Yang Z, Applegate WB, Kritchevsky SB.. JAMA Intern Med. 2015;175(3):410-419.

Statins and brain integrity in older adults: secondary analysis of the Health ABC study. Nadkarni NK, Perera S, Hanlon JT, Lopez O, Newman AB, Aizenstein H, Elam M, Harris TB, Kritchevsky S, Yaffe K, Rosano C.. Alzheimers Dement. 2015;11(10):1202-1211.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Stephen Kritchevsky, Ph.D.

Stephen Kritchevsky, Ph.D.

Deputy Director, Translational Science Institute
Director, Sticht Center on Aging
Professor, Gerontology and Geriatric Medicine
Center on Diabetes, Obesity, and Metabolism
Ctr for Vaccines at Extremes

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