Profile

Paul J. Laurienti, M.D., Ph.D.

Paul J. Laurienti, M.D., Ph.D.

Professor, Radiology
Center for Biomolecular Imaging
Sticht Center on Aging
Center for Diabetes Research
Center for Integrative Medicine
Translational Science Institute

Contact Information

Academic: 336-716-3261 | Department: 336-760-1286

Email: plaurien@wakehealth.edu

Education & Training

  • M.D., University of Texas Medical School-Galveston , 1999
  • Ph.D., University of Texas Medical School-Galveston , 1995
  • B.S., University of Houston , 1991
  • Residency, Radiology, North Carolina Baptist Hospital, 1999
  • Fellowship, University of Texas Medical School-Galveston, 1995
  • Fellowship, WFU School of Medicine, 2000

Memberships

  • Sigma Xi Society
  • Soc Of Neuroscience
  • Western Nc Chpt Soc For Neuros
Paul J. Laurienti, M.D., Ph.D.

Paul J. Laurienti, M.D., Ph.D.

Professor, Radiology Center for Biomolecular Imaging
Sticht Center on Aging
Center for Diabetes Research
Center for Integrative Medicine
Translational Science Institute

Research Interests

aging, computer science, engineering/bioengineering, information sciences, mental disorders/psychiatry/ps, model development, neurosciences/behavior, radiology/imaging, substance abuse

Contact Information

Academic: 336-716-3261 | Department: 336-760-1286

Email: plaurien@wakehealth.edu

Recent Publications

Joyce KE, Hayasaka S, Laurienti PJ. The human functional brain network demonstrates structural and dynamical resilience to targeted attack. PLoS Comput Biol. 2013;9(1):e1002885.


Li XX, Long XJ, Laurienti P, Wyatt C. Registration of images with varying topology using embedded maps. IEEE Trans Med Imaging. 2012;31(3):749-765.


Rejeski WJ, Burdette J, Burns M, Morgan AR, Hayasaka S, Norris J, Williamson DA, Laurienti PJ. Power of food moderates food craving, perceived control, and brain networks following a short-term post-absorptive state in older adults. Appetite. 2012;58(3):806-813.

Laurienti PJ. Commentary: from neuron to brain: relating neurophysiological principles of multisensory integration to the human brain In: Stein BE, ed. The new handbook of multisensory processing. Cambridge (MA): MIT Press;2012: 171-178.

Paolini B, Burdette JH, Laurienti PJ, Morgan AR, Williamson DA, Rejeski WJ. Coping with brief periods of food restriction: mindfulness matters. Front Aging Neurosci. 2012;4():article 13.

Joyce KE, Laurienti PJ, Hayasaka S. Complexity in a brain-inspired agent-based model. Neural Netw. 2012;33():275-290.

Telesford QK, Davenport AT, Kraft RA, Laurienti PJ, Daunais JB. Dynamic changes in the brain due to acute ethanol exposure in non-human primate brain networks [abstract]. Alcohol Clin Exp Res. 2012;36(Suppl 1):268A.

Joyce KE, Hayaska S, Laurienti PJ. A genetic algorithm for controlling an agent-based model of the functional human brain. Biomed Sci Instrum. 2012;48():210-217.

Moussa MN, Steen MR, Laurienti PJ, Hayasaka S. Consistency of network modules in resting-state FMRI connectome data. PLoS One. 2012;7(8):e44428.

Wilkins RW, Hodges DA, Laurienti PJ, Steen MR, Burdette JH. Network science: a new method for investigating the complexity of musical experiences in the brain. Leonardo. 2012;45(3):282-283.

Presley TD, Morgan AR, Bechtold E, Clodfelter W, Dove RW, Jennings JM, Kraft RA, King SB, Laurienti PJ, Rejeski WJ, Burdette JH, Kim-Shapiro DB, Miller GD. Acute effect of a high nitrate diet on brain perfusion in older adults. Nitric Oxide. 2011;24(1):34-42.

Simpson SL, Hayasaka S, Laurienti PJ. Exponential random graph modeling for complex brain networks. PLoS ONE. 2011;6(5):e20039.

Hayasaka S, Hugenschmidt CE, Laurienti PJ. A network of genes, genetic disorders, and brain areas. PLoS ONE. 2011;6(6):e20907.

Hanlon CA, Wesley MJ, Stapleton JR, Laurienti PJ, Porrino LJ. The association between frontal-striatal connectivity and sensorimotor control in cocaine users. Drug Alcohol Depend. 2011;115(3):240-243.

Peiffer AM, Hugenschmidt CE, Laurienti PJ. Ethics in 15 min per week. Sci Eng Ethics. 2011;17(2):289-297.

Miller G, Tennille P, Morgan A, Rejeski WJ, King SB, Jennings J, Kraft R, Laurienti P, Burdette J, Kim-Shapiro D. Acute effect of a high nitrate diet on brain perfusion in older adults [abstract]. Nitric Oxide. 2011;24(Suppl):S28.

Mozolic JL, Long AB, Morgan AR, Rawley-Payne M, Laurienti PJ. A cognitive training intervention improves modality-specific attention in a randomized controlled trial of healthy older adults. Neurobiol Aging. 2011;32(4):655-668.

Laurienti PJ, Joyce KE, Telesford QK, Burdette JH, Hayasaka S. Universal fractal scaling of self-organized networks. Physica A. 2011;390(20):3608-3613.

Steen M, Hayasaka S, Joyce K, Laurienti P. Assessing the consistency of community structure in complex networks. Phys Rev E Stat Nonlin Soft Matter Phys. 2011;84(1 Pt 2):016111.

Moussa MN, Vechlekar CD, Burdette JH, Steen MR, Hugenschmidt CE, Laurienti PJ. Changes in cognitive state alter human functional brain networks. Front Hum Neurosci. 2011;5():article 83.

Telesford QK, Simpson SL, Burdette JH, Hayasaka S, Laurienti PJ. The brain as a complex system: using network science as a tool for understanding the brain. Brain Connect. 2011;1(4):295-308.

Telesford QK, Wyatt CL, Kraft RA, Friedman DP, Laurienti PJ, Daunais JB. The effects of acute and chronic ethanol exposure in nonhuman primate brain networks [abstract]. Alcohol Clin Exp Res. 2011;35(6 Suppl):126A.

Mozolic JL, Hugenschmidt CE, Peiffer AM, Laurienti PJ. Multisensory integration and aging In: Murray MM, Wallace MT, eds. The neural basis of multisensory processes. Boca Raton (FL): CRC Press;2011: 381-395.

Steen M, Hayasaka S, Lobanov O, Laurienti P, Coghill R. Individual differences in brain networks during pain processing: a method for assessing modularity [abstract]. In: Human Brain Mapping 17th Annual Meeting Abstracts; 2011 June 26-30; Quebec City (Canada). 2011;():774.

Telesford QK, Joyce KE, Hayasaka S, Burdette JH, Laurienti PJ. The ubiquity of small-world networks. Brain Connect. 2011;1(5):367-375.

Hugenschmidt CE, Hayasaka S, Peiffer AM, Laurienti PJ. Applying capacity analyses to psychophysical evaluation of multisensory interactions. Inf Fusion. 2010;11(1 Special Issue):12-20.


Mozolic JL, Hayasaka S, Laurienti PJ. A cognitive training intervention increases resting cerebral blood flow in healthy older adults. Front Hum Neurosci. 2010;4():article 16.

Burdette JH, Laurienti PJ, Espeland MA, Morgan A, Telesford Q, Vechlekar CD, Hayasaka S, Jennings JM, Katula JA, Kraft RA, Rejeski WJ. Using network science to evaluate exercise-associated brain changes in older adults. Front Aging Neurosci. 2010;2():article 23.

Stein BE, Burr D, Constantinidis C, Laurienti PJ, Meredith MA, Perrault TJ Jr, Ramachandran R, Roder B, Rowland BA, Stanford TR, et al. Semantic confusion regarding the development of multisensory integration: a practical solution. Eur J Neurosci. 2010;31(10):1713-1720.

Joyce KE, Laurienti PJ, Burdette JH, Hayasaka S. A new measure of centrality for brain networks. PLoS ONE. 2010;5(8):e12200.

Telesford QK, Morgan AR, Hayasaka S, Simpson SL, Barret W, Kraft RA, Mozolic JL, Laurienti PJ. Reproducibility of graph metrics in fMRI networks. Front Neuroinform. 2010;4():117.

Presley TD, Morgan A, Bechtold E, Clodfelter W, Dove RW, Jennings JM, Kraft RA, King SB, Laurenti PJ[sic] [Laurienti PJ], Rejeski WJ, Burdette JH, Kim-Shapiro DB, Miller GD. Acute effect of a high nitrate diet on brain perfusion in older adults [abstract]. Free Radic Biol Med. 2010;49(Suppl 1):S119-S120.

Peiffer AM, Hugenschmidt CE, Maldjian JA, Casavona R, Srikanth R, Hayasaka S, Burdette JH, Kraft RA, Laurienti PJ. Aging and the interaction of sensory cortical function and structure. Hum Brain Mapp. 2009;30(1):228-240.

Maldjian JA, Baer AH, Kraft RA, Laurienti PJ, Burdette JH. Fully automated processing of fMRI data in SPM: from MRI scanner to PACS. Neuroinformatics. 2009;7(1):57-72.

Hugenschmidt CE, Mozolic JL, Laurienti PJ. Suppression of multisensory integration by modality-specific attention in aging. Neuroreport. 2009;20(4):349-353.

Addicott MA, Yang LL, Peiffer AM, Laurienti PJ. Methodological considerations for the quantification of self-reported caffeine use. Psychopharmacology (Berl). 2009;203(3):571-578.

Stein BE, Rowland B, Laurienti P, Stanford TR. Multisensory convergence and integration In: Squire LR, ed. Encyclopedia of neuroscience, vol 5. Berlin: Elsevier/Academic Press;2009: 1119-1124.


Hugenschmidt CE, Mozolic JL, Tan H, Kraft RA, Laurienti PJ. Age-related increase in cross-sensory noise in resting and steady-state cerebral perfusion. Brain Topogr. 2009;21(3-4):241-251.

Addicott MA, Yang LL, Peiffer AM, Burnett LR, Burdette JH, Chen MY, Hayasaka S, Kraft RA, Maldjian JA, Laurienti PJ. The effect of daily caffeine use on cerebral blood flow: how much caffeine can we tolerate?. Hum Brain Mapp. 2009;30(10):3102-3114.

Hugenschmidt CE, Peiffer AM, McCoy TP, Hayasaka S, Laurienti PJ. Preservation of crossmodal selective attention in healthy aging. Exp Brain Res. 2009;198(2-3):273-285.

Addicott MA, Laurienti PJ. A comparison of the effects of caffeine following abstinence and normal caffeine use. Psychopharmacology (Berl). 2009;207(3):423-431.

Peiffer AM, Hugenschmidt CE, Mozolic J, Laurienti PJ. Do structural MRI analyses show evidence for cognitive reserve in the healthy aging brain? [abstract]. Gerontologist. 2009;49(Suppl 2):306.

Mozolic JL, Hugenschmidt CE, Peiffer AM, Laurienti PJ. Modality-specific selective attention attenuates multisensory integration. Exp Brain Res. 2008;184(1):39-52.

Hugenschmidt CE, Peiffer AM, Kraft RA, Casanova R, Deibler AR, Burdette JH, Maldjian JA, Laurienti PJ. Relating imaging indices of white matter integrity and volume in healthy older adults. Cereb Cortex. 2008;18(2):433-442.

Peiffer AM, Maldjian JA, Laurienti PJ. Resurrecting Brinley plots for a novel use: meta-analyses of functional brain imaging data in older adults. Int J Biomed Imaging. 2008;2008():.

Casanova R, Ryali S, Serences J, Yang L, Kraft R, Laurienti PJ, Maldjian JA. The impact of temporal regularization on estimates of the BOLD hemodynamic response function: a comparative analysis. Neuroimage. 2008;40(4):1606-1618.

Maldjian JA, Laurienti PJ, Burdette JH, Kraft RA. Clinical implementation of spin-tag perfusion magnetic resonance imaging. J Comput Assist Tomogr. 2008;32(3):403-406.

Mozolic JL, Joyner D, Hugenschmidt CE, Peiffer AM, Kraft RA, Maldjian JA, Laurienti PJ. Cross-modal deactivations during modality-specific selective attention. BMC Neurol. 2008;8():article 35.

Peiffer AM, Laurienti PJ, Hugenschmidt CE. Fostering a culture of responsible lab conduct [letter]. Science. 2008;322(5905):1186.

Mozolic J, Morgan A, Laurienti P. Cognitive training impacts brain structure and function of healthy older adults in a randomized controlled trial [abstract]. Gerontologist. 2008;48(Special Issue 3):492.

Casanova R, Srikanth R, Baer A, Laurienti PJ, Burdette JH, Hayasaka S, Flowers L, Wood F, Maldjian JA. Biological parametric mapping: a statistical toolbox for multimodality brain image analysis. Neuroimage. 2007;34(1):137-143.

Peiffer AM, Mozolic JL, Hugenschmidt CE, Laurienti PJ. Age-related multisensory enhancement in a simple audiovisual detection task. Neuroreport. 2007;18(10):1077-1081.

Hayasaka S, Peiffer AM, Hugenschmidt CE, Laurienti PJ. Power and sample size calculation for neuroimaging studies by non-central random field theory. Neuroimage. 2007;37(3):721-730.

Laurienti PJ, Burdette JH, Maldjian JA, Wallace MT. Enhanced multisensory integration in older adults. Neurobiol Aging. 2006;27(8):1155-1163.

Srikanth R, Casanova R, Laurienti PJ, Peiffer AM, Maldjian JA. Estimation of false discovery rates for wavelet-denoised statistical parametric maps. Neuroimage. 2006;33(1):72-84.

Wyatt CL, Laurienti PJ. Nonrigid registration of images with different topologies using embedded maps. Conf Proc IEEE Eng Med Biol Soc. 2006;1():4823-4827.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Professor, Radiology

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