Profile

Sang Jin Lee, Ph.D.Wake Forest School of Medicine

Sang Jin Lee, Ph.D.

Associate Professor,

Contact Information

Academic: 336-713-7288 | Department: 336-716-2011

Email: sjlee@wakehealth.edu

Additional Languages

Korean

Education & Training

  • B.S., Korea-Hannam University, 1998
  • M.S., Korea-Hannam University, 2000
  • Ph.D., Korea-Hanyang University, 2003
  • Fellowship, Childrens Hospital Of Boston, 2003
  • Fellowship, WFU School of Medicine, 2006
Sang Jin Lee, Ph.D.

Sang Jin Lee, Ph.D.

Associate Professor, Institute for Regenerative Medicine

Research Interests

atherosclerosis/thrombosis, engineering/bioengineering, radiology imaging/nuclear medi, surgery/trauma/burns/trauma, vascular diseases

Contact Information

Academic: 336-713-7288 | Department: 336-716-2011

Email: sjlee@wakehealth.edu

Recent Publications

Ahn H, Ju YM, Takahashi H, Williams DF, Yoo JJ, Lee SJ, Okano T, Atala A. Engineered small diameter vascular grafts by combining cell sheet engineering and electrospinning technology. Acta Biomater. 2015;16():14-22.

Atala AJ, Yoo JJ, Grace L, Lim G, Lee SJ, inventors; Wake Forest University Health Sciences, assignee. Production of tissue engineered digits and limbs. United States patent US 9,039,782. 2015 May 26. 2015;():.

Merceron TK, Burt M, Seol YJ, Kang HW, Lee SJ, Yoo JJ, Atala A. A 3D bioprinted complex structure for engineering the muscle-tendon unit. Biofabrication. 2015;7(3):035003.

Park JH, Hong JM, Ju YM, Jung JW, Kang HW, Lee SJ, Yoo JJ, Kim SW, Kim SH, Cho DW. A novel tissue-engineered trachea with a mechanical behavior similar to native trachea. Biomaterials. 2015;62():106-115.

Chandra P, Lee SJ. Synthetic extracellular microenvironment for modulating stem cell behaviors. Biomark Insights. 2015;10(Suppl 1):105-116.

Lee SJ, Yoo JJ, Atala A. Recent applications of polymeric biomaterials and stem cells in tissue engineering and regenerative medicine. Polymer [Korea]. 2014;38(2):113-128.

Kang H-W, Kengla C, Lee SJ, Yoo JJ, Atala A. 3-D organ printing technologies for tissue engineering applications In: Narayan R, ed. Rapid prototyping of biomaterials: principles and applications. Oxford: Woodhead publishing;2014: 236-253.

Kim J, Andersson KE, Jackson JD, Lee SJ, Atala A, Yoo JJ. Downregulation of metabolic activity increases cell survival under hypoxic conditions: potential applications for tissue engineering. Tissue Eng Part A. 2014;20(15-16):2265-2272.

Niu G, Sapoznik E, Lu P, Criswell T, Mohs AM, Wang G, Lee SJ, Xu Y, Soker S. Fluorescent imaging of endothelial cells in bioengineered blood vessels: the impact of crosslinking of the scaffold. J Tissue Eng Regen Med. 2014;():.

Ju YM, Atala A, Yoo JJ, Lee SJ. In situ regeneration of skeletal muscle tissue through host cell recruitment. Acta Biomater. 2014;10(10):4332-4339.

Melgarejo Y, Garcia J, Gutierrez C, Lee SJ, Yoo J, Atala A, Ibarra C, Velasquillo C. Development of elastic cartilage using a 3D bioprinted ear shape structure, potential for ear reconstruction [abstract]. J Tissue Eng Regen Med. 2014;8(Suppl 1):462-463.

Seol YJ, Kang HW, Lee SJ, Atala A, Yoo JJ. Bioprinting technology and its applications. Eur J Cardiothorac Surg. 2014;46(3):342-348.

Jackson JR, Ko IK, Lee SJ, Atala A, Yoo J. Formation of neuromuscular junction for accelerated recovery of muscle function [abstract]. J Am Coll Surg. 2014;219(3 Suppl):S139-S140.

Jeong C, Chung HY, Lim HJ, Lee JW, Choi KY, Yang JD, Cho BC, Lim JO, Yoo JJ, Lee SJ, Atala AJ. Applicability and safety of in vitro skin expansion using a skin bioreactor: a clinical trial. Arch Plast Surg. 2014;41(6):661-667.

Ahn H, Ju Y, Takahashi H, Okano T, Yoo JJ, Atala A, Lee S. Tissue-engineered vascular grafts by combining cell sheet and electrospun scaffold [abstract]. Tissue Eng Part A. 2014;20(Suppl 1):S94.

Burt MA, Merceron T, Lee SJ, Jackson JD, Yoo JJ, Atala A. Bioprinting technology for repair of a musculotendinous defect in the gastrocnemius-achilles junction of nude rats [abstract]. Tissue Eng Part A. 2014;20(Suppl 1):S134.

He T, Lee S, King MW. Integrated multistructural scaffold for interfacial tissue engineering [abstract]. Tissue Eng Part A. 2014;20(Suppl 1):S106.

Ju Y, Ahn H, Kim C, Lee J, Yoo JJ, Atala A, Lee S. A cellularized electrospun vascular scaffold for blood vessel regeneration [abstract]. Tissue Eng Part A. 2014;20(Suppl 1):S36.

Ju Y, Shapiro L, Ko I, Yoo JJ, Atala A, Lee S. Host stem cell recruitment for in situ muscle tissue regeneration [abstract]. Tissue Eng Part A. 2014;20(Suppl 1):S97.

Kengla C, Seol Y, Kim H, Kang H, Lee S, Yoo JJ, Atala A. Biofabrication of tissue constructs for craniomaxillofacial reconstruction [abstract]. Tissue Eng Part A. 2014;20(Suppl 1):S33.

Kim J, Seol Y, Ko I, Kang H, Lee S, Atala A, Yoo JJ. 3-D bioprinting of skeletal muscle constructs for reconstruction [abstract]. Tissue Eng Part A. 2014;20(Suppl 1):S98.

Kim N, Kim S, Yoo JJ, Atala A, Lee S. Combined delivery of small RNAs for in situ muscle regeneration [abstract]. Tissue Eng Part A. 2014;20(Suppl 1):S32-S33.

Merceron T, Lee J, Kengla C, Kang H, Kim H, Lee S, Yoo JJ, Atala A. 3-D bioprinting for muscle-tendon unit regeneration [abstract]. Tissue Eng Part A. 2014;20(Suppl 1):S97.

Ryu S, Mondal A, Gutierrez S, Marco J, Ju Y, Lee S, Atala A, Yoo J, Jackson J. Characterization of thymus scaffolds for engineering thymus tissue [abstract]. Tissue Eng Part A. 2014;20(Suppl 1):S83.

Skardal A, Mead I, Devarasetty M, Kang H, Shupe T, Lee S, Jackson JD, Bishop CE, Yoo JJ, Soker S, Atala A. Integration of 3-D organoid bioprinting and microfluidic device technology for functional primary cell-based liver-on-a-chip operation [abstract]. Tissue Eng Part A. 2014;20(Suppl 1):S43.

Hwang CM, Ay B, Kaplan DL, Rubin JP, Marra KG, Atala A, Yoo JJ, Lee SJ. Assessments of injectable alginate particle-embedded fibrin hydrogels for soft tissue reconstruction. Biomed Mater. 2013;8(1):014105.

Kim J, Jeong SY, Ju YM, Yoo JJ, Smith TL, Khang G, Lee SJ, Atala A. In vitro osteogenic differentiation of human amniotic fluid-derived stem cells on a poly(lactide-co-glycolide) (PLGA)-bladder submucosa matrix (BSM) composite scaffold for bone tissue engineering. Biomed Mater. 2013;8(1):014107.

Lee SJ, Atala A. Scaffold technologies for controlling cell behavior in tissue engineering [editorial]. Biomed Mater. 2013;8(1):010201.

Xu W, Atala A, Yoo JJ, Lee SJ. Controllable dual protein delivery through electrospun fibrous scaffolds with different hydrophilicities. Biomed Mater. 2013;8(1):014104.

Ko IK, Lee BK, Lee SJ, Andersson KE, Atala A, Yoo JJ. The effect of in vitro formation of acetylcholine receptor (AChR) clusters in engineered muscle fibers on subsequent innervation of constructs in vivo. Biomaterials. 2013;34(13):3246-3255.

Owens EA, Hyun H, Kim SH, Lee JH, Park G, Ashitate Y, Choi J, Hong GH, Alyabyev S, Lee SJ, Khang G, Henary M, Choi HS. Highly charged cyanine fluorophores for trafficking scaffold degradation. Biomed Mater. 2013;8(1):014109.

Kim SH, Lee JH, Hyun H, Ashitate Y, Park G, Robichaud K, Lunsford E, Lee SJ, Khang G, Choi HS. Near-infrared fluorescence imaging for noninvasive trafficking of scaffold degradation. Sci Rep. 2013;3():1198.

Whited BM, Hofmann MC, Lu P, Xu Y, Rylander CG, Wang G, Sapoznik E, Criswell T, Lee SJ, Soker S, Rylander MN. Dynamic, nondestructive imaging of a bioengineered vascular graft endothelium. PLoS One. 2013;8(4):e61275.

Zhao W, Ju YM, Christ G, Atala A, Yoo JJ, Lee SJ. Diaphragmatic muscle reconstruction with an aligned electrospun poly(epsilon-caprolactone)/collagen hybrid scaffold. Biomaterials. 2013;34(33):8235-8240.

Ko IK, Lee SJ, Atala A, Yoo JJ. In situ tissue regeneration through host stem cell recruitment. Exp Mol Med. 2013;45():e57.

Goncalves AI, Rodrigues MT, Lee SJ, Atala A, Yoo JJ, Reis RL, Gomes ME. Understanding the role of growth factors in modulating stem cell tenogenesis. PLoS One. 2013;8(12):e83734.

Ko IK, Ju YM, Chen T, Atala A, Yoo JJ, Lee SJ. Combined systemic and local delivery of stem cell inducing/recruiting factors for in situ tissue regeneration. FASEB J. 2012;26(1):158-168.

Jordan JE, Williams JK, Lee S-J, Raghavan D, Atala A, Yoo JJ. Bioengineered self-seeding heart valves. J Thorac Cardiovasc Surg. 2012;143(1):201-208.

Joo S, Ko IK, Atala A, Yoo JJ, Lee SJ. Amniotic fluid-derived stem cells in regenerative medicine research. Arch Pharm Res. 2012;35(2):271-280.

Rodrigues MT, Lee B-K, Lee SJ, Gomes ME, Reis RL, Atala A, Yoo JJ. The effect of differentiation stage of amniotic fluid stem cells on bone regeneration. Biomaterials. 2012;33(26):6069-6078.

Lee J, Yoo JJ, Atala A, Lee SJ. Controlled heparin conjugation on electrospun poly(epsilon-caprolactone)/gelatin fibers for morphology-dependent protein delivery and enhanced cellular affinity. Acta Biomater. 2012;8(7):2549-2558.

Rodrigues MT, Lee SJ, Gomes ME, Reis RL, Atala A, Yoo JJ. Bilayered constructs aimed at osteochondral strategies: the influence of medium supplements in the osteogenic and chondrogenic differentiation of amniotic fluid-derived stem cells. Acta Biomater. 2012;8(7):2795-2806.

Lee J, Yoo JJ, Atala A, Lee SJ. The effect of controlled release of PDGF-BB from heparin-conjugated electrospun PCL/gelatin scaffolds on cellular bioactivity and infiltration. Biomaterials. 2012;33(28):6709-6720.

Hwang CM, Atala A, Yoo J, Jackson J, Lee SJ. A porous injectable hydrogel system for soft tissue regeneration [abstract]. J Tissue Eng Regen Med. 2012;6(Suppl 1):158.

Joo S, Helms A, Sivanandane S, Jackson JD, Soker S, Lee SJ, Atala A, Opara E, Yoo JJ. Development of ovarian follicle-like structures [abstract]. J Tissue Eng Regen Med. 2012;6(Suppl 1):131.

Kim J, Hwang A, Khouri R, Andersson K-E, Lee SJ, Jackson J, Atala A, Yoo J. Down-regulation of cellular metabolism improves cell survival under hypoxic conditions [abstract]. J Tissue Eng Regen Med. 2012;6(Suppl 1):275.

Kim SH, Lee SJ, Lee JH, Hyun H, Ashitate Y, Frangioni JV, Khang G, Choi HS. Real-time imaging quantification of scaffold degradation using invisible near-infrared fluorescence [abstract]. J Tissue Eng Regen Med. 2012;6(Suppl 1):317.

Ko IK, Ju YM, DeLeon J, Atala A, Yoo JJ, Lee SJ. Combined systemic and local delivery of stem cell recruitment for in situ tissue regeneration [abstract]. J Tissue Eng Regen Med. 2012;6(Suppl 1):116.

Lee BK, Ju YM, Cho JG, Jackson JD, Lee SJ, Atala A, Yoo JJ. End-to-side neurorrhaphy using an electrospun PCL/collagen nerve conduit for complex peripheral motor nerve regeneration. Biomaterials. 2012;33(35):9027-9036.

Niu G, Sapoznik E, Criswell T, Lee SJ, Soker S. Genipin cross-linked poly(epsilon-caprolactone)/collagen scaffolds for vascular graft applications [abstract]. J Tissue Eng Regen Med. 2012;6(Suppl 1):144-145.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Sang Jin Lee, Ph.D.

Sang Jin Lee, Ph.D.

Associate Professor, Institute for Regenerative Medicine

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