Profile

Sang Jin Lee, Ph.D.

Sang Jin Lee, Ph.D.

Assistant Professor, Institute for Regenerative Medicine
Center for Biomolecular Imaging

Contact Information

Academic: 336-713-7288 | Department: 336-716-2011

Email: sjlee@wakehealth.edu

Additional Languages

Korean

Education & Training

  • Ph.D., , 2003
  • B.S., , 1998
  • M.S., , 2000
  • Fellowship, Childrens Hospital Of Boston, 2003
  • Fellowship, WFU School of Medicine, 2006
Sang Jin Lee, Ph.D.

Sang Jin Lee, Ph.D.

Assistant Professor, Institute for Regenerative Medicine Center for Biomolecular Imaging

Research Interests

biotechnology, cell growth, differentiation,d, engineering/bioengineering, surgery/trauma/burns/trauma, transplantation, vascular diseases

Contact Information

Academic: 336-713-7288 | Department: 336-716-2011

Email: sjlee@wakehealth.edu

Recent Publications

Hwang CM, Ay B, Kaplan DL, Rubin JP, Marra KG, Atala A, Yoo JJ, Lee SJ. Assessments of injectable alginate particle-embedded fibrin hydrogels for soft tissue reconstruction. Biomed Mater. 2013;8(1):014105.





Owens EA, Hyun H, Kim SH, Lee JH, Park G, Ashitate Y, Choi J, Hong GH, Alyabyev S, Lee SJ, Khang G, Henary M, Choi HS. Highly charged cyanine fluorophores for trafficking scaffold degradation. Biomed Mater. 2013;8(1):014109.

Kim SH, Lee JH, Hyun H, Ashitate Y, Park G, Robichaud K, Lunsford E, Lee SJ, Khang G, Choi HS. Near-infrared fluorescence imaging for noninvasive trafficking of scaffold degradation. Sci Rep. 2013;3():1198.

Ko IK, Ju YM, Chen T, Atala A, Yoo JJ, Lee SJ. Combined systemic and local delivery of stem cell inducing/recruiting factors for in situ tissue regeneration. FASEB J. 2012;26(1):158-168.

Jordan JE, Williams JK, Lee S-J, Raghavan D, Atala A, Yoo JJ. Bioengineered self-seeding heart valves. J Thorac Cardiovasc Surg. 2012;143(1):201-208.

Joo S, Ko IK, Atala A, Yoo JJ, Lee SJ. Amniotic fluid-derived stem cells in regenerative medicine research. Arch Pharm Res. 2012;35(2):271-280.

Rodrigues MT, Lee B-K, Lee SJ, Gomes ME, Reis RL, Atala A, Yoo JJ. The effect of differentiation stage of amniotic fluid stem cells on bone regeneration. Biomaterials. 2012;33(26):6069-6078.




Hwang CM, Atala A, Yoo J, Jackson J, Lee SJ. A porous injectable hydrogel system for soft tissue regeneration [abstract]. J Tissue Eng Regen Med. 2012;6(Suppl 1):158.

Joo S, Helms A, Sivanandane S, Jackson JD, Soker S, Lee SJ, Atala A, Opara E, Yoo JJ. Development of ovarian follicle-like structures [abstract]. J Tissue Eng Regen Med. 2012;6(Suppl 1):131.

Kim J, Hwang A, Khouri R, Andersson K-E, Lee SJ, Jackson J, Atala A, Yoo J. Down-regulation of cellular metabolism improves cell survival under hypoxic conditions [abstract]. J Tissue Eng Regen Med. 2012;6(Suppl 1):275.

Kim SH, Lee SJ, Lee JH, Hyun H, Ashitate Y, Frangioni JV, Khang G, Choi HS. Real-time imaging quantification of scaffold degradation using invisible near-infrared fluorescence [abstract]. J Tissue Eng Regen Med. 2012;6(Suppl 1):317.

Ko IK, Ju YM, DeLeon J, Atala A, Yoo JJ, Lee SJ. Combined systemic and local delivery of stem cell recruitment for in situ tissue regeneration [abstract]. J Tissue Eng Regen Med. 2012;6(Suppl 1):116.

Lee BK, Ju YM, Cho JG, Jackson JD, Lee SJ, Atala A, Yoo JJ. End-to-side neurorrhaphy using an electrospun PCL/collagen nerve conduit for complex peripheral motor nerve regeneration. Biomaterials. 2012;33(35):9027-9036.

Niu G, Sapoznik E, Criswell T, Lee SJ, Soker S. Genipin cross-linked poly(epsilon-caprolactone)/collagen scaffolds for vascular graft applications [abstract]. J Tissue Eng Regen Med. 2012;6(Suppl 1):144-145.

Arenas JE, Ahn H, Hill TK, Young JM, Chang H, Yoo J, Lee SJ. Dual seeded polycaprolactone (PCL)/collagen electrospun vascular scaffold for engineering small diameter blood vessel and clinical translation [abstract]. J Am Coll Surg. 2012;215(3 Suppl):S139-S140.

Lee B, JU YM, Cho J, Lee SJ, Jackson JD, Yoo JJ, Atala A. Use of a neighboring uninjured nerve for restoration of tissue function [abstract]. J Am Coll Surg. 2012;215(3 Suppl):S145.

Rodrigues MT, Lee SJ, Gomes ME, Reis RL, Atala A, Yoo JJ. Amniotic fluid-derived stem cells as a cell source for bone tissue engineering. Tissue Eng Part A. 2012;18(23-24):2518-2527.

Ladd MR, Lee SJ, Stitzel JD, Atala A, Yoo JJ. Co-electrospun dual scaffolding system with potential for muscle-tendon junction tissue engineering. Biomaterials. 2011;32(6):1549-1559.

Komura M, Kim J, Atala A, Yoo JJ, Lee SJ. The digit: engineering of phalanges and small joints In: Atala A, Lanza R, Thomson JA, Nerem R, eds. Principles of regenerative medicine. 2nd ed. San Diego (CA): Academic Press;2011: 1091-1103.

Lee SJ, Broda C, Atala A, Yoo JJ. Engineered cartilage covered ear implants for auricular cartilage reconstruction. Biomacromolecules. 2011;12(2):306-313.

Kang T-Y, Kang H-W, Hwang CM, Lee SJ, Park J, Yoo JJ, Cho D-W. The realistic prediction of oxygen transport in a tissue-engineered scaffold by introducing time-varying effective diffusion coefficients. Acta Biomater. 2011;7(9):3345-3353.

Rodrigues MT, Lee BK, Shiner T, Lee SJ, Atala A, Yoo J, Gomes ME, Reis RL. The effect of the differentiation stage of amniotic fluid stem cells seeded onto biodegradable scaffolds in the regeneration of non-union defects [abstract]. Int J Artif Organs. 2011;34(8):611-612.

Lim GJ, Lee SJ, Atala A. Cell-based drug delivery In: Atala A, Lanza R, Thomson JA, Nerem RM, eds. Foundations of regenerative medicine: clinical and therapeutic applications. Boston (MA): Academic Press/Elsevier;2010: 518-530.

Ju YM, Choi JS, Atala A, Yoo JJ, Lee SJ. Bilayered scaffold for engineering cellularized blood vessels. Biomaterials. 2010;31(15):4313-4321.

Ju YM, Choi JS, Aboushwareb T, Atala A, Yoo J, Lee SJ. Bilayered vascular scaffolds for engineering cellularized small diameter blood vessels [abstract]. J Am Coll Surg. 2010;211(3 Suppl):S144-S145.

Tillman BW, Yazdani SK, Lee SJ, Geary RL, Atala A, Yoo JJ. The in vivo stability of electrospun polycaprolactone-collagen scaffolds in vascular reconstruction. Biomaterials. 2009;30(4):583-588.

Jung SH, Kim SH, Yang JC, Hong HH, Kim HL, Kim W, Son Y, Lee SJ, van Dyke M, Yoo JJ, et al. [Effect of keratin/PLGA scaffold on the articular cartilage tissue engineering: in vivo test] [Korean]. Tissue Eng Regen Med. 2009;6(1-3):192-198.

Oh AY, Kim SH, Kim CM, Jung SH, Jeon NR, Hong HH, Lee SJ, van Dyke M, Yoo JJ, Lee DW, et al. [The effect of keratin/PLGA scaffold on neural differentiation of rat BMSCs] [Korean]. Tissue Eng Regen Med. 2009;6(1-3):112-118.

Ladd MR, Lee SJ, Atala A, Yoo JJ. Bioreactor maintained living skin matrix. Tissue Eng Part A. 2009;15(4):861-868.

Oh AY, Kim SH, Kim YT, Jeon NR, Yang JC, Lee SJ, Yoo JJ, van Dyke M, Shin HS, Rhee JM, et al. [A study on proliferation and phenotypical stability of Schwann cell on keratin/PLGA film] [Korean]. Polymer [Korea]. 2009;33(2):118-123.

Liu Y, Bharadwaj S, Lee SJ, Atala A, Zhang Y. Optimization of a natural collagen scaffold to aid cell-matrix penetration for urologic tissue engineering. Biomaterials. 2009;30(23-24):3865-3873.

Jeon NR, Jo EH, Park HJ, Choi JS, Lee SJ, Van Dyke M, Lee JJ, Lee D, Rhee JM, Khang G. Effects of keratin/PLGA scaffolds on proliferation and phenotype of olafactory ensheathing cells. Tissue Eng Regen Med. 2009;6(4-11 Special Issue):819-824.

Ladd MR, Aboushwareb TA, Lee SJ, Atala A, Yoo J. Integrated scaffolding system for the engineering of muscle-tendon junction [abstract]. J Am Coll Surg. 2009;209(3 Suppl):S62.

Tillman BW, Aboushwareb TA, Yazdani SK, Lee SJ, Geary RL, Atala A, Yoo JJ. Electrospun vascular scaffolds as a bypass graft: a feasibility study in vivo [abstract]. J Am Coll Surg. 2009;209(3 Suppl):S140.

Lee SJ, Harrison B, Czerw R, Yoo JJ, Atala A, Lim JO. Regulated heparin release using novel quantum dots for potential application to vascular graft engineering. J Macromol Sci, Pure Appl Chem. 2009;46(12):1191-1198.

Lim GJ, Lee SJ, Atala A. Cell-based drug delivery In: Atala A, Lanza R, Thomson JA, Nerem RM, eds. Principles of regenerative medicine. Boston (MA): Academic Press;2008: 954-966.

Lee SJ, Oh SH, Liu J, Soker S, Atala A, Yoo JJ. The use of thermal treatments to enhance the mechanical properties of electrospun poly (epsilon-caprolactone) scaffolds. Biomaterials. 2008;29(10):1422-1430.


Lee SJ, Liu J, Oh SH, Soker S, Atala A, Yoo JJ. Development of a composite vascular scaffolding system that withstands physiological vascular conditions. Biomaterials. 2008;29(19):2891-2898.

Lee SJ, Lee JW, Lim G, Atala A, Yoo JJ. Composite scaffolds for bone tissue regeneration [abstract]. Tissue Eng Part A. 2008;14(5):714.

Lee SJ, Van Dyke M, Atala A, Yoo JJ. Host cell mobilization for in situ tissue regeneration. Rejuvenation Res. 2008;11(4):747-756.

Oh AY, Kim SH, Lee SJ, Yoo JJ, Van Dyke M, Rhee JM, Khang G. [Preparation and characterization of PLGA scaffold impregnated keratin for tissue engineering application] [Korean]. Polymer [Korea]. 2008;32(5):403-408.

Hong HH, Kim SH, Oh AY, Jeon NR, Jung SH, Lee SJ, Van Dyke M, Yoo JJ, Son Y, Rhee JM, et al. [Effect of keratin/PLGA hybrid scaffold for chondrogenesis: in vitro test] [Korean]. Tissue Eng Regen Med. 2008;5(4-6):861-868.

Oh AY, Kim SH, Jung SH, Hong HH, Jeon NR, Lee SJ, Van Dyke M, Yoo JJ, Rhee JM, Khang G. [Effect of keratin/PLGA scaffold on proliferation and phenotype of Schwann cell] [Korean]. Tissue Eng Regen Med. 2008;5(4-6):855-860.

Harrison BS, Eberli D, Lee SJ, Atala A, Yoo JJ. Oxygen producing biomaterials for tissue regeneration. Biomaterials. 2007;28(31):4628-4634.

Harrison BS, Eberli D, Lee SJ, Oh SH, Ward C, Atala A, Yoo JJ. Oxygen generating scaffolds for tissue regeneration [abstract]. Tissue Eng. 2007;13(7):1740.

Lee SJ, Van Dyke M, Atala A, Yoo JJ. Stem/progenitor cell mobilization for tissue regeneration [abstract]. Tissue Eng. 2007;13(7):1757.

Lee SJ, Yoo JJ, Lim GJ, Atala A, Stitzel J. In vitro evaluation of electrospun nanofiber scaffolds for vascular graft application. J Biomed Mater Res A. 2007;83(4):999-1008.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Assistant Professor, Institute for Regenerative Medicine

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