Research Interests
cancer/oncogenesis
,
drugs/therapeutic agents pharm
Recent Publications
Kota G, Gupta P, Wilson J, Lesser G, Mintz A.
Metastatic intracranial hemangiopericytoma: the role of octreotide and PET imaging in diagnosis, pre-treatment and follow-up evaluation [abstract]. J Nucl Med.
2011;
52(Suppl 1):abstr 1065.
Batchelor T, Grossman S, Brem S, Lesser G, Voloschin A, Nabors LB, Mikkelsen T, Desideri S, Supko J, Peereboom D.
Feasibility and phase I/II trial of tandutinib in patients with recurrent glioblastoma [abstract]. Neuro Oncol.
2011;
13(Suppl 3):89.
Cole VR, Kennedy LD, Lesser G.
Risk factors and treatment for post-dural puncture headache in oncology patients [abstract]. Neuro Oncol.
2011;
13(Suppl 3):94.
Paulsson AK, Chan MD, Peiffer AM, Hinson WH, Kearns WT, Lesser GJ, Ellis TL, Tatter SB, Shaw EG, McMullen KP.
Decreased CTV margin size does not affect patterns of failure for glioblastoma treated with concurrent radiotherapy and temozolomide [abstract]. Int J Radiat Oncol Biol Phys.
2011;
81(2 Suppl):S183.
Attia A, Case LD, D'Agostino R Jr, Lesser GJ, McMullen K, Naughton MJ, Rapp SR, Rosdhal R, Shaw EG.
Phase II study of ginkgo biloba in irradiated brain tumor survivors: effects on quality of life (QOL), mood, and cognitive function [abstract]. J Clin Oncol.
2010;
28(Suppl):e12523.
Case LD, Naughton MJ, Lesser GJ, Rapp SR, Vitolins M, Sheidler VR, Enevold GL, Shaw EG.
Recruitment and retention in the Wake Forest University CCOP Research Base [abstract]. J Clin Oncol.
2010;
28(Suppl):e19543.
Naughton MJ, Case LD, Meyers CA, Loghin ME, Shaw EG, Saphner TJ, Sleckman BG, Giguere JK, Lesser GJ, Rapp SR.
Quality of life (QOL) and cognitive performance among irradiated brain cancer patients [abstract]. J Clin Oncol.
2010;
28(Suppl 7):abstr 9131.
Lesser GJ, Case LD, Stark N, Williford SK, Giguere JK, Garino A, Naughton MJ, Vitolins M, Lively M, Shaw EG.
A randomized double-blind placebo-controlled study of oral coenzyme Q10 to relieve self-reported cancer-treatment-related fatigue in newly diagnosed breast cancer patients [abstract]. J Clin Oncol.
2010;
28(15 Suppl):9006.
Grossman SA, Ye X, Lesser GJ, Sloan AE, Carson C, Piantadosi S.
Iatrogenic immunosuppression in patients with high-grade gliomas treated with radiation and temozolomide: a NABTT CNS Consortium study [abstract]. J Clin Oncol.
2010;
28(15 Suppl):2013.
Vitolins M, Lesser GJ, Case LD, Williford SK, Giguere JK, Garino A, Naughton MJ, Lively M, Melin SA, Shaw EG.
Self-reported compliance compared to biomarker levels of vitamin E in breast cancer patients participating in a CoQ10 clinical trial [abstract]. J Clin Oncol.
2010;
28(15 Suppl):e19524.
Nabors LB, Fink K, Reardon DA, Lesser GJ, Trusheim J, Raval SN, Hicking C, Picard M, Mikkelsen T.
Cilengitide in patients with newly diagnosed glioblastoma multiforme and unmethylated MGMT gene promoter: protocol of a multicenter, randomized, open-label, controlled phase II study [abstract]. J Clin Oncol.
2010;
28(15 Suppl):TPS151.
High KP, Case LD, Siegel RD, Metzner-Sidurski J, Krauss JC, Chinnasami B, Sanders GH, Rousey S, Lesser GJ, Shaw EG.
A phase III randomized, double-blind, placebo controlled trial of North American (NA) ginseng (Panax quinquefolium) extract (CVT-E002) in patients with chronic lymphocytic leukemia: effect on respiratory infection and antibiotic use [abstract]. J Clin Oncol.
2010;
28(15 Suppl):6578.
Peereboom DM, Supko JG, Carson KA, Batchelor T, Phuphanich S, Lesser G, Mikkelson T, Fisher J, Desideri S, He X, et al.
A phase I/II trial and pharmacokinetic study of ixabepilone in adult patients with recurrent high-grade gliomas. J Neurooncol.
2010;
100(2):261-268.
Hammond SN, Norden AD, Drappatz J, Phuphanich S, Reardon D, Wong ET, Plotkin SR, Lesser G, Mintz A, Raizer JJ, et al.
Phase II study of monthly pasireotide LAR (Som230C) for recurrent or progressive meningioma [abstract]. Neuro Oncol.
2010;
12(71 Suppl 4):71.
Renfrow J, De Troye A, Chan M, Tatter S, Ellis T, McMullen K, Johnson A, Mott R, Lesser GJ.
Initial clinical experience with bendamustine in patients with recurrent primary central nervous system lymphoma (R-PCNSL) [abstract]. Neuro Oncol.
2010;
12(Suppl 4):56.
Norden AD, Lesser G, Hammond SN, Drappatz J, Fadul CE, Batchelor TT, Quant EC, Beroukhim R, Ciampa A, Doherty L, et al.
Phase II study of dose-intense temozolomide in recurrent glioblastoma [abstract]. Neuro Oncol.
2010;
12(Suppl 4):iv71.
Fiveash J, Nabors LB, Mikkelsen T, Peereboom DM, Lesser GJ, Chowdhary SA, Grossman S, Ye X, Leopold L, Rosenfeld M.
A phase I study of AT-101 plus radiotherapy and temozolomide and AT-101 plus adjuvant temozolomide for patients with newly diagnosed glioblastoma multiforme [abstract]. Neuro Oncol.
2009;
11(5):666.
Lesser GJ, Blackwood R, Harmon M.
Temozolomide-induced semen analysis: changes in men with newly diagnosed or recurrent malignant glioma [abstract]. Neuro Oncol.
2009;
11(5):658.
Ruiz J, Lesser GJ.
Low-grade gliomas. Curr Treat Options Oncol.
2009;
10(3-4):231-242.
Lesser GJ, Carver KA, Newton SJ, Tallant EA, Gallagher PE.
Angiotensin-(1-7), a small molecule inhibitor of glioblastoma growth [abstract]. J Clin Oncol.
2009;
27(15 Suppl):2024.
Fiveash JB, Chowdhary SA, Peereboom D Jr, Mikkelsen T, Nabors LB, Lesser GJ, Rosenfeld MR, Ye X, Grossman SA.
A phase II study of R-(-)-gossypol (AT-101) in recurrent glioblastoma multiforme (GBM) [abstract]. J Clin Oncol.
2009;
27(15 Suppl):2010.
Nabors LB, Mikkelson T, Batchelor T, Lesser G, Rosenfeld M, Ye X, Piantadosi S, Olson J, Brem S, Grossman S.
A randomized phase II trial of EMD 121974 in conjunction with concomitant and adjuvant temozolomide with radiation therapy in patients with newly diagnosed glioblastoma multiforme (GBM) [abstract]. J Clin Oncol.
2009;
27(15 Suppl):2001.
Rosenfeld MR, Chamberlain M, Grossman SA, Peereboom DM, Lesser GJ, Batchelor TT, Desideri S, Salazar AM, Ye X.
A phase II study of chemoradiation followed by adjuvant temozolomide and poly-ICLC in patients with newly diagnosed glioblastoma: 12- and 18- month survival data [abstract]. J Clin Oncol.
2009;
27(15 Suppl):2002.
Supko JG, Grossman SA, Peereboom DM, Chowdhary S, Lesser GJ, Nabors LB, Mikkelson T, Desideri S, Batchelor TT.
Feasibility and phase I trial of tandutinib in patients with recurrent glioblastoma [abstract]. J Clin Oncol.
2009;
27(15 Suppl):2039.
Monjazeb AM, Bourland JD, Case LD, Ellis TL, Lesser GJ, McMullen KP, Munley M, Tatter SB, Shaw EG.
A phase I dose escalation study of IMRT field-in-field boost for newly diagnosed glioblastoma multiforme (GBM) [abstract]. Int J Radiat Oncol Biol Phys.
2008;
72(1 Suppl 1):S227.
Lesser G, Carver K, Newton S, Tallant EA, Gallagher P.
Angiotensin-(1-7) inhibits the growth of human glioblastoma xenografts in nude mice [abstract]. Neuro Oncol.
2008;
10(5):792.
Streiff MB, Grossman SA, Ye X, Kickler TS, Lesser GJ, Batchelor TT, Jani JT, Desideri S.
Elevated factor VIII activity is common in patients with newly diagnosed high-grade gliomas [abstract]. J Clin Oncol.
2008;
26(15 Suppl Pt I):97s.
Batchelor TT, Lesser GJ, Grossman SA.
Rituximab monotherapy for relapsed or refractory primary central nervous system lymphoma [abstract]. J Clin Oncol.
2008;
26(15 Suppl Pt I):99s.
Rosenfeld MR, Chamberlain MC, Grossman SA, Peereboom DM, Lesser GJ, Batchelor TT, Desideri S, Salazar AM, Ye X.
A phase II trial of radiation plus temozolomide followed by adjuvant temozolomide and poly-ICLC in patients with newly diagnosed glioblastoma multiforme (NABTT #0501) [abstract]. J Clin Oncol.
2008;
26(15 Suppl Pt I):102s.
Murray CE, D'Agostino R Jr, Lesser GJ.
Retreatment with a prolonged temozolomide (TMZ) dosing schedule in patients (pts) with recurrent malignant gliomas (MG) [abstract]. J Clin Oncol.
2008;
26(15 Suppl Pt I):108s.
Lesser GJ, Case D, Ottery F, McQuellon R, Choksi JK, Sanders G, Rosdhal R, Shaw EG.
A phase III randomized study comparing the effects of oxandrolone (Ox) and megestrol acetate (Meg) on lean body mass (LBM), weight (wt) and quality of life (QOL) in patients with solid tumors and weight loss receiving chemotherapy [abstract]. J Clin Oncol.
2008;
26(15 Suppl Pt I):505s.
Grossman SA, Desideri S, Ye X, Szajna K, Chamberlain M, Lesser G.
Iatrogenic immunosuppression in patients with newly diagnosed high-grade gliomas [abstract]. J Clin Oncol.
2007;
25(18 Suppl Pt I):78s.
Lesser GJ, Stieber V, Case D, Enevold G, Rosdhal R, Tatter S, Ellis T, McMullen K, Shaw E.
A phase II trial of thalidomide (Thal) and procarbazine (Pro) in adults with recurrent or progressive malignant gliomas (MG) [abstract]. J Clin Oncol.
2007;
25(18 Suppl Pt I):91s.
Phuphanich S, Chamberlain M, Mikkelsen T, Ye X, Grossman SA, Batchelor T, Lesser G, Fisher JD, Desideri S.
A phase I study of SDX-102 for the treatment of patients with MTAP-deficient recurrent malignant gliomas [abstract]. J Clin Oncol.
2007;
25(18 Suppl Pt I):90s.
Grossman S, Desideri S, Piantadosi S, Lesser G, Chamberlain M, Ye XB.
Treatment-induced immunosuppression in newly diagnosed high-grade gliomas: a NABTT CNS consortium study [abstract]. Neuro Oncol.
2007;
9(4):521.
Voelzke WR, Graves JT, Hemphill MB, Gibo DM, Debinski W, Petty WJ, Lesser G.
Pre-clinical evaluation of erlotinib and 13-cis-retinoic acid for the treatment of malignant gliomas [abstract]. Neuro Oncol.
2007;
9(4):492.
Butler JM Jr, Case LD, Frizzell B, Lesser G, McMullen K, McQuellon R, Naughton M, Rapp S, Stieber V, Shaw EG, et al.
A phase III, double-blind, placebo-controlled prospective randomized clinical trial of d-threo-methylphenidate HCl in brain tumor patients receiving radiation therapy. Int J Radiat Oncol Biol Phys.
2007;
69(5):1496-1501.
Phuphanich S, Supko J, Carson KA, Grossman SA, Nabors LB, Mikkelsen T, Lesser G, Rosenfeld M, Desideri S, Olson J.
Phase I trial of bortezomib in adults with recurrent malignant glioma [abstract]. J Clin Oncol.
2006;
24(18 Suppl Pt I):74s.
Phuphanich S, Supko J, Carson KA, Grossman SA, Nabors LB, Mikkelsen T, Lesser G, Rosenfeld M, Desideri S, Olson J.
A phase I evaluation of the safety of bortezomib with biologic proteosome 20S activity correlation and the effects of anticonvulsants in adults with recurrent malignant glioma [abstract]. Neuro Oncol.
2006;
8(4):449.
All Publications
For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.
For a list of earlier publications, visit the Carpenter Library Publication Search.