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Nicole Hope Levi, Ph.D.Wake Forest School of Medicine

Nicole Hope Levi, Ph.D.

Associate Professor,

Clinical Interests

Emergence-based Drug Delivery, Wound Healing Problems, Breast Cancer

Contact Information

Academic: 336-713-8052 | Department: 336-716-4171


Education & Training

  • M.S., Clemson University, 2002
  • Ph.D., WFU Sch of Med/Va Tech Biomedical Engineering & Sc, 2007


  • Biomedical Engineering Society
Nicole Hope Levi, Ph.D.

Nicole Hope Levi, Ph.D.

Associate Professor, Plastic & Reconstructive Surgery

Research Interests

Nanotubes, Carbon; Phototherapy; Polymers; Cell Movement; Hyperthermia, Induced
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Contact Information

Academic: 336-713-8052 | Department: 336-716-4171


Recent Publications

Introduction to the special issue on thermal therapy and infectious diseases [editorial]. Chopra R, Levi-Polyachenko N, Smeltzer MS.. Int J Hyperthermia. 2018;34(2):133-134.

Progress on utilizing hyperthermia for mitigating bacterial infections. Ibelli T, Templeton S, Levi-Polyachenko N.. Int J Hypertens. 2018;34(2):144-156.

Low band gap conjugated polymeric compositions and appications thereof. Carroll DL, Levi-Polyachenko NH, MacNeill C, Graham E, inventors; Wake Forest University Health Sciences, assignee.. Australia patent AU. 2017 Mar 23. 2017;():.

Small-scale pressure sensors. Carroll DL, Coldren F, Levi-Polyachenko NH, Webb LX, Werner BC, Smith TL, Wagner WD, inventors; Wake Forest University Health Sciences, assignee.. United States patent US 9,671,301. 2017 Jun 6. 2017;():.

Structural and mechanical characterization of bioresorbable, elastomeric nanocomposites from poly(glycerol sebacate)/nanohydroxyapatite for tissue transport applications. Rosenbalm TN, Teruel M, Day CS, Donati GL, Morykwas M, Argenta L, Kuthirummal N, Levi-Polyachenko N.. J Biomed Mater Res B Appl Biomater. 2016;104(7):1366-1373.

Multi-walled nanotubes for cellular reprogramming of cancer. Wailes EM, Levi-Polyachenko NH.. Nanomedicine. 2016;12(4):955-963.

Shaping PEDOT nanoparticles for use in 3D tissue phantoms. Wailes EM, MacNeill CM, McCabe E, Levi-Polyachenko NH.. J Appl Polym Sci. 2016;133(18):43378.

Multi-walled carbon nanotubes inhibit breast cancer cell migration. Graham EG, Wailes EM, Levi-Polyachenko NH.. J Biomed Nanotechnol. 2016;12(2):308-319.

Chitosan wound dressing with hexagonal silver nanoparticles for hyperthermia and enhanced delivery of small molecules. Levi-Polyachenko N, Jacob R, Day C, Kuthirummal N.. Colloids Surf B Biointerfaces. 2016;142():315-324.

Ultrafast optical nonlinearity and photoacoustic studies on chitosan-boron nitride nanotube composite films. Kuthirummal N, Philip R, Mohan A, Jenks C, Levi-Polyachenko N.. Opt Commun. 2016;371():47-50.

Dual wavelength stimulation of polymeric nanoparticles for photothermal therapy. Kelkar SS, McCabe-Lankford E, Albright R, Harrington P, Levi-Polyachenko NH.. Lasers Surg Med. 2016;48(9):893-902.

Development and characterization of elastic nanocomposites for craniofacial contraction osteogenesis. Levi-Polyachenko N, Rosenbalm T, Kuthirummal N, Shelton J, Hardin W, Teruel M, Hobley E, Wang R, Day C, Narayanan V, David L, Wagner WD.. J Biomed Mater Res B Appl Biomater. 2015;103(2):407-416.

Novel nanofiber-based material for endovascular scaffolds. Wang R, Levi-Polyanchenko N, Morykwas M, Argenta L, Wagner WD.. J Biomed Mater Res A. 2015;103(3):1150-1158.

Soft template synthesis of donor-acceptor conjugated polymer nanoparticles: structural effects, stability, and photothermal studies. MacNeill CM, Graham EG, Levi-Polyachenko NH.. J Polym Sci A1. 2014;52(11):1622-1632.

Differential response of MCF7, MDA-MB-231, and MCF 10A cells to hyperthermia, silver nanoparticles and silver nanoparticle-induced photothermal therapy. Thompson EA, Graham E, MacNeill CM, Young M, Donati G, Wailes EM, Jones BT, Levi-Polyachenko NH.. Int J Hyperthermia. 2014;30(5):312-323.

Eradicating group A streptococcus bacteria and biofilms using functionalised multi-wall carbon nanotubes. Levi-Polyachenko N, Young C, MacNeill C, Braden A, Argenta L, Reid S.. Int J Hyperthermia. 2014;30(7):490-501.

MWNTs inhibit breast cancer migration [abstract]. Wailes E, Levi-Polyachendo N.. FASEB J. 2014;28(1 Suppl):1048.5.

Low band gap donor-acceptor conjugated polymer nanoparticles and their NIR-mediated thermal ablation of cancer cells. MacNeill CM, Coffin RC, Carroll DL, Levi-Polyachenko NH.. Macromol Biosci. 2013;13(1):28-34.

Quantifying folic acid-functionalized multi-walled carbon nanotubes bound to colorectal cancer cells for improved photothermal ablation. Graham EG, MacNeill CM, Levi-Polyachenko NH.. J Nanopart Res. 2013;15(5):1649.

A comparative study of the photothermal efficiency of electrically conducting poly(3,4-ethylenedioxythiophene)-based nanomaterials with cancer cells. MacNeill CM, Wailes EM, Levi-Polyachenko NH.. J Nanosci Nanotechnol. 2013;13(6):3784-3791.

Heart valve substitute fabricated from silk protein, collagen, and poly-glycerol sebacate has enhanced endothelial cell growth and reduced thrombogenicity [abstract]. Wagner WD, Wang R, Levi-Polyachenko N.. FASEB J. 2013;27():527.4.

Compositions and methods for treating cancer. Carroll DL, Stewart JH IV, Levi-Polyachenko NH, inventors; Wake Forest University Health Sciences, assignee.. United States patent US 8,501,233. 2013 Aug 6. 2013;():.

Production of a biodegradable electrospun biomaterial with tensile strength and elasticity [abstract]. Wagner WD, Argenta LC, Morykwas MJ, Levi-Polyachenko N.. FASEB J. 2012;26(Meeting Abstracts Suppl):905.2.

Device and method for treating central nervous system pathology. Argenta LC, Carroll DL, Levi NH, Liu J, Morykwas MJ, Tatter S, Wagner WD, inventors; Wake Forest University Health Sciences and Wake Forest University, assignees.. United States patent 8,267,960. 2012 Sept 8. 2012;():.

Nanoparticles in natural aquatic systems and cellular toxicity [abstract]. Ringwood AH, McCarthy M, Levi-Polyachenko N, Carroll DL.. Comp Biochem Physiol A Mol Integr Physiol. 2010;157(1 Suppl):S53.

Encapsulated Staphylococcus aureus strains vary in adhesiveness assessed by atomic force microscopy. Coldren FM, Palavecino EL, Levi-Polyachenko NH, Wagner WD, Smith TL, Smith BP, Webb LX, Carroll DL.. J Biomed Mater Res A. 2009;89(2):402-410.

Swelling and pressure-volume relationships in the dermis measured by osmotic-stress technique. McGee MP, Morykwas M, Levi-Polyachenko N, Argenta L.. Am J Physiol Regul Integr Comp Physiol. 2009;296(6):R1907-1913.

Rapid photothermal intracellular drug delivery using multiwalled carbon nanotubes. Levi-Polyachenko NH, Merkel EJ, Jones BT, Carroll DL, Stewart JH.. Mol Pharm. 2009;6(4):1092-1099.

Fullerene exposures with oysters: embryonic, adult, and cellular responses. Ringwood AH, Levi-Polyachenko N, Carroll DL.. Environ Sci Technol. 2009;43(18):7136-7141.

Long-term survival following a single treatment of kidney tumors with multiwalled carbon nanotubes and near-infrared radiation. Burke A, Singh R, Kraft RA, Levi-Polyachenko N, Hatcher HC, D'Agostino R Jr, Kock ND, Carroll DL, Akman S, Torti FM, Torti SV, et al.. Proc Natl Acad Sci U S A. 2009;106(31):12897-902.

Applications of carbon-based nanomaterials for drug delivery in oncology. Levi-Polyachenko NH, Carroll DL, Stewart JH IV. In: Cataldo F, Da Ros T, eds. Medicinal chemistry and pharmacological potential of fullerenes and carbon nanotubes. Berlin: Springer;2008: 223-266.

The essential role of the mitochondria and reactive oxygen species in cisplatin-mediated enhancement of Fas ligand-induced apoptosis in malignant pleural mesothelioma. Stewart JH IV, Tran T-L, Levi N, Tsai WS, Schrump DS, Nguyen DM.. J Surg Res. 2007;141(1):120-131.

C60-Fullerenes: detection of intracellular photoluminescence and lack of cytotoxic effects. Levi N, Hantgan RR, Lively MO, Carroll DL, Prasad GL.. J Nanobiotechnol. 2006;4():article 14.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Associate Professor, Plastic & Reconstructive Surgery

Clinical Interests

Emergence-based Drug Delivery, Wound Healing Problems, Breast Cancer
Nicole Hope Levi, Ph.D.

Nicole Hope Levi, Ph.D.

Associate Professor, Plastic & Reconstructive Surgery

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