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Mingxia LiuWake Forest School of Medicine

Mingxia Liu


Contact Information

Academic: 336-716-9221 | Department: 336-713-4259


Education & Training

  • M.B.,B.S., Peking University, 2008
  • Doctor of Philosophy, Wake Forest University, 2013
Mingxia Liu

Mingxia Liu

Instructor, Molecular Medicine
Center on Diabetes, Obesity, and Metabolism
Office of Women in Medicine and Science

Contact Information

Academic: 336-716-9221 | Department: 336-713-4259


Recent Publications

Targeted deletion of adipocyte Abca1 (ATP-binding cassette transporter A1) impairs diet-induced obesity. Cuffe H, Liu M, Key CC, Boudyguina E, Sawyer JK, Weckerle A, Bashore A, Fried SK, Chung S, Parks JS.. Arterioscler Thromb Vasc Biol. 2018;38(4):733-743.

Feeding of tobacco blend or nicotine induced weight loss associated with decreased adipocyte size and increased physical activity in male mice. Liu M, Chuang Key CC, Weckerle A, Boudyguina E, Sawyer JK, Gebre AK, Spoo W, Makwana O, Parks JS.. Food Chem Toxicol. 2018;113():287-295.

Hepatocyte ABCA1 deletion impairs liver insulin signaling and lipogenesis. Key CC, Liu M, Kurtz CL, Chung S, Boudyguina E, Dinh TA, Bashore A, Phelan PE, Freedman BI, Osborne TF, Zhu X, Ma L, Sethupathy P, Biddinger SB, Parks JS.. Cell Rep. 2017;19(10):2116-2129.

Hepatic ABCA1 deficiency is associated with delayed apolipoprotein B secretory trafficking and augmented VLDL triglyceride secretion. Liu M, Chung S, Shelness GS, Parks JS.. Biochim Biophys Acta. 2017;1862(10 Pt A):1035-1043.

LRP1 integrates murine macrophage cholesterol homeostasis and inflammatory responses in atherosclerosis. Xian X, Ding Y, Dieckmann M, Zhou L, Plattner F, Liu M, Parks JS, Hammer RE, Boucher P, Tsai S, Herz J.. Elife. 2017;6():e29292.

Apolipoprotein M improves survival in congestive heart failure via enhanced Akt signaling [abstract]. Javaheri A, Shewale S, Frej C, Liu MX, Bedi K, Brandimarto J, Mu AB, Wang T, Chen CY, Ma XC, Zamani P, French B, Margulies KB Cappola TP, Prosser BL, Diwan A, Dahlback B, Parks JS, Rader DJ.. J Card Fail. 2016;22(8 Suppl):S1.

Uncleaved ApoM signal peptide is required for formation of large ApoM/sphingosine 1-phosphate (S1P)-enriched HDL particles. Liu M, Allegood J, Zhu X, Seo J, Gebre AK, Boudyguina E, Cheng D, Chuang CC, Shelness GS, Spiegel S, Parks JS.. J Biol Chem. 2015;290(12):7861-7870.

Hepatic apolipoprotein M (apoM) overexpression stimulates formation of larger apoM/sphingosine 1-phosphate-enriched plasma high density lipoprotein. Liu M, Seo J, Allegood J, Bi X, Zhu X, Boudyguina E, Gebre AK, Avni D, Shah D, Sorci-Thomas MG, Thomas MJ, Shelness GS, Spiegel S, Parks JS.. J Biol Chem. 2014;289(5):2801-2814.

Myeloid cell-specific ATP-binding cassette transporter A1 deletion has minimal impact on atherogenesis in atherogenic diet-fed low-density lipoprotein receptor knockout mice. Bi X, Zhu X, Gao C, Shewale S, Cao Q, Liu M, Boudyguina E, Gebre AK, Wilson MD, Brown AL, Parks JS.. Arterioscler Thromb Vasc Biol. 2014;34(9):1888-1899.

Myeloid cell-specific ABCA1 deletion does not worsen insulin resistance in HF diet-induced or genetically obese mouse models. Zhu X, Chung S, Bi X, Chuang CC, Brown AL, Liu M, Seo J, Cuffe H, Gebre AK, Boudyguina E, Parks JS.. J Lipid Res. 2013;54(10):2708-2717.

Overexpression of apoM in liver stimulates formation of larger, apoM/S1P-enriched plasma HDL [abstract]. Liu MX, Seo JM, Allegood J, Bi X, Zhu XW, Boudyguina E, Gebre AK, Sorci-Thomas M, Thomas MS, Shelness GS, Spiegel S, Parks JS.. Circulation. 2013;128(22 Suppl):A19183.

CGI-58/ABHD5-derived signaling lipids regulates systemic inflammation and insulin action. Lord CC, Betters JL, Ivanova PT, Milne SB, Myers DS. Madenspacher J, Thomas G, Chung S, Liu M, Davis MA, Lee RG, Crooke RM, Graham MJ, Parks JS, Brasaemle DL, Fessler MB, Brown HA, Brown JM.. Diabetes. 2012;61(2):355-363.

Hepatic ABCA1 and VLDL triglyceride production. Liu M, Chung S, Shelness GS, Parks JS.. Biochim Biophys Acta. 2012;1821(5):770-777.

Macrophage 12/15 lipoxygenase expression increases plasma and hepatic lipid levels and exacerbates atherosclerosis. Rong S, Cao Q, Liu M, Seo J, Jia L, Boudyguina E, Gebre AK, Colvin PL, Smith TL, Murphy RC, Mishra N, Parks JS.. J Lipid Res. 2012;53(4):686-695.

Myeloid cell-specific ABCA1 deletion protects mice from bacterial infection. Zhu X, Westcott MM, Bi X, Liu M, Gowdy KM, Seo J, Cao Q, Gebre AK, Fessler MB, Hiltbold EM, Parks JS.. Circ Res. 2012;111(11):1398-1409.

Defective vesicle trafficking is associated with increased VLDL triglyceride secretion in hepatocyte-specific ABCA1 knockout mice [abstract]. Liu M, Chung S, Parks JS.. Arterioscler Thromb Vasc Biol. 2009;29(7):e35.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Instructor, Molecular Medicine

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