Profile

Mark O. Lively, Ph.D.

Mark O. Lively, Ph.D.

Professor, Biochemistry
Translational Science Institute
Institute for Regenerative Medicine
Translational Science Institute
Contact Information
Office:
336-716-2969
Email: mlively@wakehealth.edu
Education & Training
  BS Georgia Institute of Technology 1975
  PhD Georgia Institute of Technology 1978
Fellowship Georgia Institute of Technology 1979
  University of Washington 1982
Memberships
Protein Society
American Society of Biochem & Molecular Biology
American Society of Mass Spectrometry
Association of Biomolecular Resource Facilities
Mark O. Lively, Ph.D.

Mark O. Lively, Ph.D.

Professor, Biochemistry
Translational Science Institute
Institute for Regenerative Medicine
Translational Science Institute
Contact Information
Office:
336-716-2969
Email: mlively@wakehealth.edu
Research Interests
cancer/oncogenesis , genomics and proteomics
Recent Publications
Govan JM, Lively MO, Deiters A. Photochemical control of DNA decoy function enables precise regulation of nuclear factor kappaB activity. J Am Chem Soc. 2011; 133(33):13176-82.

Ahmad S, Simmons T, Varagic J, Moniwa N, Chappell MC, Lively M, Ferrario CM. Localization and metabolism of angiotensin-(1-12) in human atrial tissue [abstract]. Hypertension. 2011; 58(5):e50.

Lesser GJ, Case LD, Stark N, Williford SK, Giguere JK, Garino A, Naughton MJ, Vitolins M, Lively M, Shaw EG. A randomized double-blind placebo-controlled study of oral coenzyme Q10 to relieve self-reported cancer-treatment-related fatigue in newly diagnosed breast cancer patients [abstract]. J Clin Oncol. 2010; 28(15 Suppl):9006.

Vitolins M, Lesser GJ, Case LD, Williford SK, Giguere JK, Garino A, Naughton MJ, Lively M, Melin SA, Shaw EG. Self-reported compliance compared to biomarker levels of vitamin E in breast cancer patients participating in a CoQ10 clinical trial [abstract]. J Clin Oncol. 2010; 28(15 Suppl):e19524.

Byerley LO, Lee SH, Culberson C, Clemens M, Lively MO. Evidence for a novel serum factor distinct from zinc alpha-2 glycoprotein that promotes body fat loss early in the development of cachexia. Nutr Cancer. 2010; 62(4):484-494.

Young DD, Lively MO, Deiters A. Activation and deactivation of DNAzyme and antisense function with light for the photochemical regulation of gene expression in mammalian cells. J Am Chem Soc. 2010; 132(17):6183-6193.

Mizel SB, Graff AH, Sriranganathan N, Ervin S, Lees CJ, Lively MO, Hantgan RR, Thomas MJ, Wood J, Bell B. Flagellin-F1-V fusion protein is an effective plague vaccine in mice and two species of nonhuman primates. Clin Vaccine Immunol. 2009; 16(1):21-28.

Bates DJP, Lively MO, Gorczynski MJ, King SB, Townsend AJ, Morrow CS. Noncatalytic interactions between glutathione S-transferases and nitroalkene fatty acids modulate nitroalkene-mediated activation of peroxisomal proliferator-activated receptor gamma. Biochemistry. 2009; 48(19):4159-4169.

Reading BJ, Hiramatsu N, Sawaguchi S, Matsubara T, Hara A, Lively MO, Sullivan CV. Conserved and variant molecular and functional features of multiple egg yolk precursor proteins (vitellogenins) in white perch (Morone americana) and other teleosts. Mar Biotechnol (NY). 2009; 11(2):169-187.

Young DD, Govan JM, Lively MO, Deiters A. Photochemical regulation of restriction endonuclease activity. Chembiochem. 2009; 10(10):1612-1616.

Young DD, Edwards WF, Lusic H, Lively MO, Deiters A. Light-triggered polymerase chain reaction. Chem Commun. 2008; 4():462-464.

Coffman LG, Brown JC, Johnson DA, Parthasarathy N, D'Agostino RB Jr, Lively MO, Hua X, Willingham MC, Torti FM, Torti SV, et al. Cleavage of high-molecular-weight kininogen by elastase and tryptase is inhibited by ferritin. Am J Physiol Lung Cell Mol Physiol. 2008; 294(3):L505-L515.

Lusic H, Lively MO, Deiters A. Light-activated deoxyguanosine: photochemical regulation of peroxidase activity. Mol Biosyst. 2008; 4(6):508-511.

Young DD, Lusic H, Lively MO, Yoder JA, Deiters A. Gene silencing in mammalian cells with light-activated antisense agents. Chembiochem. 2008; 9(18):2937-2940.

Ekici OD, Karla A, Paetzel M, Lively MO, Pei D, Dalbey RE. Altered-3 substrate specificity of Escherichia coli signal peptidase 1 mutants as revealed by screening a combinatorial peptide library. J Biol Chem. 2007; 282(1):417-425.

Lin Z, Johnson LC, Weissbach H, Brot N, Lively MO, Lowther WT. Free methionine-(R)-sulfoxide reductase from Escherichia coli reveals a new GAF domain function. Proc Natl Acad Sci U S A. 2007; 104(23):9597-9602.

Lusic H, Young DD, Lively MO, Deiters A. Photochemical DNA activation. Org Lett. 2007; 9(10):1903-1906.

Newbern J, Taylor A, Robinson M, Lively MO, Milligan CE. c-Jun N-terminal kinase signaling regulates events associated with both health and degeneration in motoneurons. Neuroscience. 2007; 147(3):680-692.

Patel VB, Spencer CH, Young TA, Lively MO, Cunningham CC. Effects of 4-hydroxynonenal on mitochondrial 3-hydroxy-3-methylglutaryl (HMG-CoA) synthase. Free Radic Biol Med. 2007; 43(11):1499-1507.

Ho M, Onda M, Wang Q-c, Hassan R, Pastan I, Lively MO. Mesothelin is shed from tumor cells [letter]. Cancer Epidemiol Biomarkers Prev. 2006; 15(9):1751.

Levi N, Hantgan RR, Lively MO, Carroll DL, Prasad GL. C60-Fullerenes: detection of intracellular photoluminescence and lack of cytotoxic effects. J Nanobiotechnol. 2006; 4():article 14.
All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Back To Top
Last Updated 3/28/2012
Quick Reference
Request an Appointment
New Patients
336-716-WAKE
888-716-WAKE
Existing patients may contact the clinic directly.
Locate Faculty

e.g., "allergy," "diabetes"

US News Best Hospital AwardANCC Magnet Association AwardBest Doctors 2011-2012 AwardConsumer Choice #1 Award 2011-2102US News Best Medical Schools 2011 Award

Disclaimer: The information on this website is for general informational purposes only and SHOULD NOT be relied upon as a substitute for sound professional medical advice, evaluation or care from your physician or other qualified health care provider.