Research Interests
aging
,
arthritis
,
hormones/cytokines/signalling
,
molecular biology/molecular me
Recent Publications
Houston DK, Davis C, Legault C, Hausman DB, Nicklas BJ, Loeser RF, Kritchevsky SB, Messier SP.
Serum 25-hydroxyvitamin D and physical function in older adults with knee osteoarthritis [abstract]. FASEB J.
2011;
25(Meeting Abstracts):abstr 97.6.
Loeser RF, Erickson EA, Long DA [sic] [Long DL].
Rac1 and NADPH oxidase regulate NF kappa B activity and MMP-13 expression in chondrocytes in response to integrin activation [abstract]. Arthritis Rheum.
2011;
63(10 Suppl):S702.
Messier SP, Nicklas BJ, Legault C, Mihalko S, Miller GD, DeVita P, Lyles M, Hunter DJ, Eckstein F, Williamson JD, Carr JJ, Loeser RF.
The Intensive Diet and Exercise for Arthritis Trial: 18-month clinical outcomes [abstract]. Arthritis Rheum.
2011;
63(10 Suppl):S281.
Loeser RF, Olex A, Chou J, McNulty MA, Carlson CS, Callahan M, Ferguson C, Fetrow JS.
The effects of age on disease severity and gene expression in the destabilized medial meniscus (DMM) model of OA in mice [abstract]. In: Transactions of the 56th Annual Meeting of the Orthopaedic Research Society; 2010 Mar 6-9; New Orleans (LA).
2010;
():Abstr 345.
Olex A, Loeser R, Chou J, Callahan M, Ferguson C, Fetrow JS.
Microarray analysis reveals age-related differences in gene expression during the development of osteoarthritis in mice [abstract]. Genome Biol.
2010;
11(Suppl 1):P29.
Loeser R, Fetrow J, Chou J, Nicklas B, Kritchevsky SB.
Using gene microarrays to discover skeletal muscle mechanisms underlying clinical responses to diet and exercise interventions [abstract]. Gerontologist.
2010;
50(Suppl 1):80.
Loeser RF Jr, Delbono O.
Aging of the muscles and joints. In: Halter JB, Ouslander JG, Tinetti ME, Studenski S, High KP, Asthana S, Hazzard WR, Wollard NF, eds. Hazzard's geriatric medicine and gerontology. 6th ed.
New York: McGraw Hill Medical;
2009:
1355-1368.
Messier SP, Legault C, Mihalko S, Miller GD, Loeser RF, DeVita P, Lyles M, Eckstein F, Williamson JD, Nicklas BJ, et al.
The Intensive Diet and Exercise for Arthritis (IDEA) trial: design and rationale. BMC Musculoskelet Disord.
2009;
10():article 93.
Loeser RF, McNulty MA, TReuting PM, Carlson CS.
Reduction in articular cartilage lesions in older adult mice overexpressing catalase targeted to mitochondria [abstract]. Osteoarthritis Cartilage.
2009;
17(Suppl 1):S27.
Loeser RF, Yin W.
Reactive oxygen species contribute to IGF-I resistance in osteoarthritic chondrocytes through inhibition of the IRS-I-PI3 kinase-Akt signaling pathway [abstract]. Arthritis Rheum.
2009;
60(Suppl 10):1911.
Loeser RF, Yin W.
Reactive oxygen species inhibit IGF-I induction of chondrocyte porteoglycan synthesis through differential regulation of PI-3 kinase-AKT and MEK-ERK MAPK signaling pathways [abstract]. Osteoarthritis Cartilage.
2009;
17(Suppl 1):S36-S37.
Atif U, Philip A, Aponte J, Woldu EM, Brady S, Kraus VB, Jordan JM, Doherty M, Wilson AG, Loeser R, et al.
Absence of association of asporin polymorphisms and osteoarthritis susceptibility in US Caucasians. Osteoarthritis Cartilage.
2008;
16(10):1174-1177.
Anderson AS, Loeser R, Carr J, Claudine L [sic] [Legault C], Nicklas B, Stephen M [sic] [Messier S].
Quadriceps muscle quality correlates with physical performance in obese and overweight adults with knee osteoarthritis: preliminary data from the IDEA study [abstract]. Arthritis Rheum.
2008;
58(12):3992.
Kraus VB, Jordan JM, Doherty M, Wilson AG, Moskowitz R, Hochberg M, Loeser R, Hooper M, Renner JB, Crane MM, et al.
The genetics of generalized osteoarthitis (GOGO) study: study design and evaluation of osteoarthritis phenotypes. Osteoarthritis Cartilage.
2007;
15(2):120-127.
Carnagey KM, Miller GD, Nicklas BJ, Loeser RF.
Inflammatory biomarkers and physical function in older obese adults with knee osteoarthritis following intensive weight loss therapy [abstract]. FASEB J.
2007;
21(6):A1072.
Ramsay O, Loeser R, Nicklas B, Legault C, Messier S.
Physical function status is related to body fat mass, but not lean mass, in older adults with knee osteoarthritis [abstract]. Arthritis Rheum.
2007;
56(12):4262.
Loeser RF, Yammani R, Erickson E, King B, Poole L.
Chondrocyte MMP-13 expression in response to alpha 5 beta 1 integrin stimulation requires protein sulfenic acids as signaling intermediates [abstract]. Arthritis Rheum.
2006;
54(9 Suppl):S318.
All Publications
For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.
For a list of earlier publications, visit the Carpenter Library Publication Search.