Profile

Mary F. Lyles, M.D.Wake Forest Baptist Health

Doctor Rating

4.9 out of 5

83 Ratings
12 Comments

Mary F. Lyles, M.D.

Associate Professor,

Clinical Specialties

Obesity Treatment, Body Composition, Geriatrics, Osteoporosis, Geriatric Medicine and Assessment

Contact Information

New Patient Appointments: 336-716-WAKE
Returning Patient Appointments: 336-713-8250
Department: 336-713-8570

Insurance Accepted »

Education & Training

  • B.A., Saint Louis University , 1971
  • M.D., University of Mississippi School of Medicine , 1975
  • Internship, Internal Medicine, Misericordia Hosp Med Ctr, 1976
  • Residency, Internal Medicine, Misericordia Hosp Med Ctr, 1978
  • Fellowship, SUNY-Stony Brook, 1985

Board Certifications

  • American Board of Internal Medicine, Internal Medicine, Internal Medicine - Geriatric Medicine
  • American Board of Internal Medicine, Internal Medicine, Internal Medicine - Internal Medicine

Memberships

  • Soc Of General Internal Medici
  • Am Coll of Physicians Fellow
  • Am Geriatrics Society

NPI Number

  • 1861477804
Mary F. Lyles, M.D.

Doctor Rating

4.9 out of 5

83 Ratings
12 Comments

Mary F. Lyles, M.D.

Associate Professor, Gerontology and Geriatric Medicine
Sticht Center on Aging

Contact Information

Academic: 336-713-8116 | Department: 336-713-8570

Recent Publications


Henderson R, Leng I, Chmelo E, Brinkley TE, Lyles MF, Marsh AP, Nicklas BJ. Comparison of aerobic versus resistance training for improving gait speed in older adults [abstract]. J Am Geriatr Soc. 2014;62(Suppl 1):S154.

Kitzman DW, Nicklas B, Kraus WE, Lyles MF, Eggebeen J, Morgan TM, Haykowsky M. Skeletal muscle abnormalities and exercise intolerance in older patients with heart failure and preserved ejection fraction. Am J Physiol Heart Circ Physiol. 2014;306(9):H1364-1370.

Beavers DP, Beavers KM, Loeser RF, Walton NR, Lyles MF, Nicklas BJ, Shapses SA, Newman JJ, Messier SP. The independent and combined effects of intensive weight loss and exercise training on bone mineral density in overweight and obese older adults with osteoarthritis. Osteoarthritis Cartilage. 2014;22(6):726-733.

You T, Wang X, Murphy KM, Lyles MF, Demons JL, Yang R, Gong DW, Nicklas BJ. Regional adipose tissue hormone/cytokine production before and after weight loss in abdominally obese women. Obesity (Silver Spring). 2014;22(7):1679-1684.

Gordon MM, Chmelo E, Crotts C, Lyles M, Brinkley T, Newman J, Rejeski WJ, Nicklas B. Aerobic exercise training and self-reported fatigue in older, obese adults [abstract]. Med Sci Sports Exerc. 2014;46(5):224.

Mihalko SL, Beavers D, Miller G, Lyles M, Commander S, Carpenter M, Cook L, Messier S. Predictors of attendance to intensive diet and exercise interventions among older overweight and obese adults with knee osteoarthritis: results from the intensive diet and exercise for arthritis (IDEA) Trial [abstract]. Ann Behav Med. 2014;47(Suppl 1):S120.

Beavers DP, Beavers KM, Lyles MF, Nicklas BJ. Cardiometabolic risk after weight loss and subsequent weight regain in overweight and obese postmenopausal women. J Gerontol A Biol Sci Med Sci. 2013;68(6):691-698.

Marsh AP, Shea MK, Vance Locke RM, Miller ME, Isom S, Miller GD, Nicklas BJ, Lyles MF, Carr JJ, Kritchevsky SB. Resistance training and pioglitazone lead to improvements in muscle power during voluntary weight loss in older adults. J Gerontol A Biol Sci Med Sci. 2013;68(7):828-836.

Messier SP, Mihalko SL, Beavers DP, Nicklas BJ, Devita P, Carr JJ, Hunter DJ, Williamson JD, Bennell KL, Guermazi A, Lyles M, Loeser RF. Strength Training for Arthritis Trial (START): design and rationale. BMC Musculoskelet Disord. 2013;14():208.

Atkinson HH, Lambros A, Davis BR, Lawlor JS, Lovato J, Sink KM, Demons JL, Lyles MF, Watkins FS, Callahan KE, Williamson JD. Teaching medical student geriatrics competencies in 1 week: an efficient model to teach and document selected competencies using clinical and community resources. J Am Geriatr Soc. 2013;61(7):1182-1187.

Messier SP, Mihalko SL, Legault C, Miller GD, Nicklas BJ, DeVita P, Beavers DP, Hunter DJ, Lyles MF, Eckstein F, Williamson JD, Carr JJ, Guermazi A, Loeser RF. Effects of intensive diet and exercise on knee joint loads, inflammation, and clinical outcomes among overweight and obese adults with knee osteoarthritis: the IDEA randomized clinical trial. JAMA. 2013;310(12):1263-1273.

Brinkley TE, Gordon MM, Chmelo EA, Jefferson M, Lyles MF, Hundley WG, Gregory HW, Nicklas BJ. Aortic stiffness predicts blood pressure responses to exercise in obese older adults [abstract]. Med Sci Sports Exerc. 2013;45(5 Suppl 1):11.

Chmelo E, Gordon M, Crotts C, Lyles MF, Brinkley T, Blocker J, Nicklas BJ. Does 400 meter walk time predict Vo(2) peak in obese, older adults? [abstract]. Med Sci Sports Exerc. 2013;45(5 Suppl 1):573.

Jefferson ME, Gordon MM, Chmelo EA, Lyles MF, Nicklas BJ, Brinkley TE. Heart rate recovery is associated with central adiposity in obese older adults [abstract]. Med Sci Sports Exerc. 2013;45(5 Suppl 1):11.

Sorensen JA, Crotts C, Chmelo E, Lyles MF, Marsh AP, Nicklas BJ. Is gait speed associated with strength, power, and lower extremity function in older, overweight and obese men and women? [abstract]. Med Sci Sports Exerc. 2013;45(5 Suppl 1):644.

You TJ, Wang XW, Yang RZ, Gong D, Lyles M, Nicklas B. Effects of weight loss on subcutaneous adipose tissue hormone/cytokine production: depot comparisons [abstract]. Med Sci Sports Exerc. 2013;45(5 Suppl 1):418-419.

Wang X, You T, Lyles MF, Murphy KM, Nicklas BJ. Addiction of aerobic exercise to caloric restriction increases adiponectin circulating concentrations and release from abdominal and gluteal adipose tissue in obese/overweight postmenopausal women [abstract]. In: Obesityweek 2013 November 11-16; Atlanta (GA). 2013;():S76.

Lyles MF, Demons JL, Murphy KM, Nicklas BJ. Skeletal muscle sampling in elderly research participants with chronic disease [abstract]. J Am Geriatr Soc. 2012;60(Suppl 4):S197.

Messier SP, DeVita P, Nicklas BJ, Beavers D, Mihalko S, Miller GD, Lyles M, Hunter DJ, Eckstein F, Legault C, Williamson JD, Carr JJ, Loeser RF. The Intensive Diet and Exercise for Arthritis Trial (IDEA): effects on knee joint loading and inflammation [abstract]. Osteoarthritis Cartilage. 2012;20(Suppl 1):S28.

Walker FO, Lyles MF, Li Z. Sheet fitting palsy. J Clin Neuromuscul Dis. 2012;14(1):48-50.

Hunter DJ, Beavers D, Eckstein F, Guermazi A, Loeser RF, Nicklas BJ, Mihalko S, Miller GD, Lyles M, DeVita P, Legault C, Carr JJ, Williamson JD, Messier SP. The Intensive Diet and Exercise for Arthritis Trial (IDEA): 18-month radiographic and MRI outcomes [abstract]. Arthritis Rheum. 2012;64(10 Suppl):S1070.

Walton NR, Loeser RF, Beavers D, Nicklas BJ, Lyles M, Messier SP. The effects of intensive diet and exercise on bone density in older adults with knee osteoarthritis: the Intensive Diet and Exercise for Arthritis (IDEA) trial [abstract]. Arthritis Rheum. 2012;64(10 Suppl):S1070-71.

Beavers KM, Beavers DP, Lyles MF, Nicklas B. Body composition and cardiometabolic risk factor changes with intentional weight loss and subsequent weight regain [abstract]. Gerontologist. 2012;52(Suppl 1):701.

Shea MK, Nicklas BJ, Marsh AP, Houston DK, Miller GD, Isom S, Miller ME, Carr JJ, Lyles MF, Kritchevsky SB, et al. The effect of pioglitazone and resistance training on body composition in older men and women undergoing hypocaloric weight loss. Obesity (Silver Spring). 2011;19(8):1636-1646.

Beavers KM, Lyles MF, Davis CC, Wang X, Beavers DP, Nicklas BJ. Is lost lean mass from intentional weight loss recovered during weight regain in postmenopausal women?. Am J Clin Nutr. 2011;94(3):767-774.

Messier SP, Nicklas BJ, Legault C, Mihalko S, Miller GD, DeVita P, Lyles M, Hunter DJ, Eckstein F, Williamson JD, Carr JJ, Loeser RF. The Intensive Diet and Exercise for Arthritis Trial: 18-month clinical outcomes [abstract]. Arthritis Rheum. 2011;63(10 Suppl):S281.

Wang XW, You TJ, Yang RZ, Lyles MF, Demons J, Gong DW, Nicklas BJ. Muscle strength is associated with adipose tissue gene expression of inflammatory adipokines in postmenopausal women [research letter]. Age Ageing. 2010;39(5):656-659.

Welmerink DB, Longstreth WT Jr, Lyles MF, Fitzpatrick AL. Cognition and the risk of hospitalization for serious falls in the elderly: results from the Cardiovascular Health Study. J Gerontol A Biol Sci Med Sci. 2010;65(11):1242-1249.

Lyles MF, Murphy K, Nicklas B, Hafer-Macko C, Ryan A. Feasibility, efficacy and safety of skeletal muscle acquisition in frail elderly with comorbidities [abstract]. Gerontologist. 2010;50(Suppl 1):80.

Easter L, Nicklas BJ, Lyles MF, Gordon M. Optimizing Weight for Life in Seniors: a unique clinic to improve physical function and mobility in the elderly through weight management [abstract]. J Am Diet Assoc. 2010;110(9 Suppl 2):A-14.

Nicklas BJ, Wang X, You T, Lyles MF, Demons J, Easter L, Berry MJ, Lenchik L, Carr JJ. Effect of exercise intensity on abdominal fat loss during calorie restriction in overweight and obese postmenopausal women: a randomized, controlled trial. Am J Clin Nutr. 2009;89(4):1043-1052.

Lyles MF, Wang X, Demons J, Nicklas B. Functional consequences of weight regain 12 months after a successful weight loss intervention [abstract]. J Am Geriatr Soc. 2009;57(Suppl 1):S160.

Messier SP, Legault C, Mihalko S, Miller GD, Loeser RF, DeVita P, Lyles M, Eckstein F, Williamson JD, Nicklas BJ, et al. The Intensive Diet and Exercise for Arthritis (IDEA) trial: design and rationale. BMC Musculoskelet Disord. 2009;10():article 93.

Kritchevsky SB, Nicklas B, Denise H [sic] [Houston D], Melanie B [sic] [Bopp M], Anthony MP [sic] [Marsh AP], Gary MD [sic] [Miller GD], Lyles MF, Michael ME [sic] [Miller ME], Carr J. Evaluating strategies to optimize the body composition of older adults during voluntary weight loss [abstract]. J Am Geriatr Soc. 2008;56(4 Suppl 1):S162.

Lyles MF, Wang X, Demons JL, Nicklas BJ. Functional consequences of weight regain: changes 6 months after a successful weight loss intervention [abstract]. J Am Geriatr Soc. 2008;56(4 Suppl):S20.

Wang X, Lyles MF, You T, Berry MJ, Rejeski WJ, Nicklas BJ. Weight regain is related to decreases in physical activity during weight loss. Med Sci Sports Exerc. 2008;40(10):1781-1788.

Gordon MM, Czerwinski MJ, Bopp G, Easter L, Miller GD, Lyles MF, Houston DK, Nicklas BJ, Kritchevsky SB. Effects of dietary protein on the composition of weight loss in post-menopausal women. J Nutr Health Aging. 2008;12(8):505-509.

Nicklas BJ, Leng I, Delbono O, Kitzman DW, Marsh AP, Hundley WG, Lyles MF, O'Rourke KS, Annex BH, Kraus WE. Relationship of physical function to vastus lateralis capillary density and metabolic enzyme activity in elderly men and women. Aging Clin Exp Res. 2008;20(4):302-309.

Lyles M, Wang X, Nicklas B. Changes in weight and body composition 12 months following completion of a weight loss intervention [abstract]. Obesity (Silver Spring). 2008;16(Suppl 1):S207.

Nicklas BJ, Wang XW, You TJ, Lyles MF, Demons J. Effect of aerobic exercise intensity on loss of visceral fat and metabolic risk factors in women [abstract]. Diabetes. 2008;57(Suppl 1):A93.

Kritchevsky SB, Nicklas BJ, Lyles MF, Marsh AP, Miller GD, Miller ME, Leng X. Effect of PPAR gamma use during a hypocaloric diet for weight loss on reductions in total and visceral fat in older men and women [abstract]. Diabetes. 2008;57(Suppl 1):A482.

Lyles MF, Wang X, You T, Lenchik L, Demons JL, Nicklas BJ. Changes in weight and body composition 12 months following completion of a weight loss intervention [abstract]. J Am Geriatr Soc. 2007;55(4 Suppl):S165-S166.

Demons JL, Wang X, Lyles MF, Kritchevsky SB, Nicklas BJ. Effects of weight loss on physical performance in obese postmenopausal women [abstract]. J Am Geriatr Soc. 2007;55(4 Suppl):S164.

Wang X, You T, Lyles M, Demons J, Nicklas BJ. Adipose tissue production of inflammatory mediators is related to aerobic fitness and muscle strength in obese postmenopausal women [abstract]. Med Sci Sports Exerc. 2007;39(5 Suppl):S68.

You T, Wang X, Lyles M, Demons J, Nicklas B. Inflammatory proteins released by abdominal and gluteal subcutaneous adipose tissue: regional differences and relationships with metabolic risk factors [abstract]. Obesity. 2007;15(Suppl 1):A80-A81.

Lyles M, Demons J, Murphy K. Fat biopsy: a safe and acceptable procedure in overweight older women [abstract]. Obesity. 2007;15(Program Abstr Suppl):A188.

Lyles M, Demons J, Marsh A, O'Rourke K, Murphy K. Muscle biopsy in older adults: a safe and acceptable research procedure [abstract]. Obesity. 2007;15(Program Abstr Suppl):A187.

You T, Murphy KM, Lyles MF, Demons JL, Lenchik L, Nicklas BJ. Addition of aerobic exercise to dietary weight loss preferentially reduces abdominal adipocyte size. Int J Obes. 2006;30(8):1211-1216.

Nicklas B, You T, Lyles M, Demons J, Wang X. Weight loss via caloric restriction and aerobic exercise reduces prevalence of metabolic syndrome in older, obese women. Gerontologist. 2006;46(Special Issue 1):550.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Associate Professor, Gerontology and Geriatric Medicine

Clinical Specialties

Obesity Treatment, Body Composition, Geriatrics, Osteoporosis, Geriatric Medicine and Assessment
Mary F. Lyles, M.D.

Mary F. Lyles, M.D.

Associate Professor, Gerontology and Geriatric Medicine
Sticht Center on Aging

Doctor Rating

4.9 out of 5

Mary F. Lyles, M.D.83 Ratings
12 Comments

Doctor Ratings

The overall Patient Rating score is the average of responses to the nine questions listed below. The questions are from the Press Ganey Patient Satisfaction Survey. Responses are measured on a 1 to 5 scale, where 1 represents "very poor" and 5 represents "very good."
Press Ganey Patient Satisfaction Survey

CP concern for questions/worries
4.9
CP efforts to include in decisions
4.9
CP explanations of prob/condition
4.9
CP spoke using clear language
4.9
Friendliness/courtesy of CP
4.9
Likelihood of recommending CP
5
Patients' confidence in CP
4.9
Time CP spent with patient
4.9
Wait time at clinic
4.7



Patient Comments

Comments are taken from the Care Provider section of the Press Ganey Patient Satisfaction Survey. Comments are posted exactly as they are written. Comments are added weekly. To protect patient privacy and confidentiality, patient names are not included.

8/7/2014

Mary Lyles is the IDEAL physician. She spent time this year coming to check on me in the hospital under different physician's care. After this last visit she researched immunization not in the Epic system. I feel like she has my back when another physician fails to do a complete job. It would be wonderful if you recognized her before she retires. She is a wonderful, caring, researching, teaching physician who has made a real difference in my life.

7/28/2014

*Dr. Lyles is a most caring person and I receive wonderful care from her.

7/22/2014

Since I do have a modicum of medical knowledge, Dr. Lyles makes sure to keep me completely informed in all aspects of my care.

6/30/2014

*Dr. Lyles has always been a very efficient, caring physician who treats me and my health problems with respect. She explains everything in detail in a way that I understand fully. I could not ask for a better doctor.

6/21/2014

Always good!

6/13/2014

*Mary Lyles MD is a wonderful doctor - I feel better just talking to her; treats me with respect and complete information - talks to me like an adult.

5/23/2014

She's extraordinary.

5/22/2014

I sing her praises to anyone who will listen. I presented her with an issue of some concern -- a lump in my breast -- and she scheduled an appointment with a surgeon immediately. I saw him within the week.

5/7/2014

No bad experiences.

4/25/2014

MD. #10. Her excellence is WIDELY known.

4/11/2014

*Dr. Lyles explained on MRI that had not been explained by the cardiology attending. Very important!!

3/17/2014

Very satisfactory.

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