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Linda C. McPhail, Ph.D.

Linda C. McPhail, Ph.D.

Associate Dean,
Professor, Biochemistry
Women's Health Center of Excellence for Research, Leadership, Education
Comprehensive Cancer Center
Translational Science Institute
Infectious Diseases
Molecular Medicine
Translational Science Institute
Contact Information
Office:
336-716-2621
Email: lmcphail@wakehealth.edu
Education & Training
  BS Methodist College 1970
  MS Wake Forest University 1973
  PhD Wake Forest University 1976
Fellowship Natl Jewish Hosp/Res Ctr 1980
Memberships
American Association for the Advancement of Science
Society for Leukocyte Biology
American Society for Biochemistry and Molecular Biology
American Society for Cell Biology
Linda C. McPhail, Ph.D.

Linda C. McPhail, Ph.D.

Associate Dean,
Professor, Biochemistry
Women's Health Center of Excellence for Research, Leadership, Education
Comprehensive Cancer Center
Translational Science Institute
Infectious Diseases
Molecular Medicine
Translational Science Institute
Contact Information
Office:
336-716-2621
Email: lmcphail@wakehealth.edu
Recent Publications
Mishra M, Byrd MS, Sergeant S, Azad AK, Parsek MR, McPhail L, Schlesinger LS, Wozniak DJ. Pseudomonas aeruginosa Psl polysaccharide reduces neutrophil phagocytosis and the oxidative response by limiting complement-mediated opsonization. Cell Microbiol. 2012; 14(1):95-106.

Davis NY, McPhail LC, Horita DA. Backbone 1H, 15N, and 13C resonance assignments for the NOXO1 beta PX domain. Biomol NMR Assign. 2011; 5(2):139-141.

Lewis EM, Sergeant S, Ledford B, Stull N, Dinauer MC, McPhail LC. Phosphorylation of p22phox on threonine 147 enhances NADPH oxidase activity by promoting p47phox binding. J Biol Chem. 2010; 285(5):2959-2967.

McPhail LC. Effect of splice-site mutations in X-linked chronic granulomatous disease [reply to letter]. Clin Immunol. 2009; 130(2):234.

Chial HJ, Wu R, Ustach CV, McPhail LC, Mobley WC, Chen YQ. Membrane targeting by APPL1 and APPL2: dynamic scaffolds that oligomerize and bind phosphoinositides. Traffic. 2008; 9(2):215-229.

Lewis EM, Singla M, Sergeant S, Koty PP, McPhail LC. X-linked chronic granulomatous disease secondary to skewed X chromosome inactivation in a female with a novel CYBB mutation and late presentation. Clin Immunol. 2008; 129(2):372-380.

Shen K, Sergeant S, Hantgan RR, McPhail LC, Horita DA. Mutations in the PX-SH3A linker of p47phox decouple PI(3,4)P2 binding from NADPH oxidase activation. Biochemistry. 2008; 47(34):8855-8865.

Lehman N, Ledford B, Di Fulvio M, Frondorf K, McPhail LC, Gomez-Cambronero J. Phospholipase D2-derived phosphatidic acid binds to and activates ribosomal p70 S6 kinase independently of mTOR. FASEB J. 2007; 21(4):1075-1087.

Taylor RM, Lord CI, Riesselman MH, Gripentrog JM, Leto TL, McPhail LC, Berdichevsky Y, Pick E, Jesaitis AJ. Characterization of surface structure and p47phox SH3 domain-mediated conformational changes for human neutrophil flavocytochrome b. Biochemistry. 2007; 46(49):14291-304.

Sergeant S, McPhail LC. Measurement of phospholipid metabolism in intact neutrophils. Methods Mol Biol. 2007; 412():69-83.
All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

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Last Updated 3/13/2012
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