Giselle C. Melendez ZapataWake Forest School of Medicine

Giselle C. Melendez Zapata


Clinical Interests

Cardiac Disease, Cardiovascular Disease Preventions and Genetics

Contact Information

Academic: 336-713-7086 | Department: 336-716-6674

Additional Languages


Education & Training

  • B.A., Venezuela, 1995
  • M.D., Central Univ Faculty of Medicine-Venezuela, 2003
  • Fellowship, Cell Biology, University of South Carolina M, 2011


  • Am Heart Association
  • Am Physiological Society
Giselle C. Melendez Zapata

Giselle C. Melendez Zapata

Instructor, Cardiology
Comprehensive Cancer Center
Center for Comparative Medicine Research
Pathology-Comparative Medicine

Research Interests

cardiac function

Contact Information

Academic: 336-713-7086 | Department: 336-716-6674

Recent Publications

Levick SP, Melendez GC. Targeting substance P and relaxin [letter]. Int J Cardiol. 2016;204():154-155.

Melendez GC, Register TC, Appt SE, Clarkson TB, Franke AA, Kaplan JR. Beneficial effects of soy supplementation on postmenopausal atherosclerosis are dependent on pretreatment stage of plaque progression. Menopause. 2015;22(3):289-296.

Melendez GC, Manteufel EJ, Dehlin HM, Register TC, Levick SP. Non-human primate and rat cardiac fibroblasts show similar extracellular matrix-related and cellular adhesion gene responses to substance P. Heart Lung Circ. 2015;24(4):395-403.

Jordan JH, Vasu S, Morgan T, D'Agostino R, Melendez GC, Hall M, Hamilton C, Arai A, Liu S, Liu C-Y, Lima J, Bluemke D, Hundley W. Myocardial extracellular volume is elevated in cancer survivors treated with anthracycline-based chemotherapy compared to cancer-free peers and newly diagnosed and untreated cancer patients: a single-center observational study of the. J Am Coll Cardiol. 2015;65(10 Suppl):A1081.

Vera T, D'Agostino RB Jr, Jordan JH, Whitlock MC, Melendez GC, Lamar ZS, Porosnicu M, Bonkovsky HL, Poole LB, Hundley WG. Relation of pre-anthracycline serum bilirubin levels to left ventricular ejection fraction after chemotherapy. Am J Cardiol. 2015;116(11):1752-1755.

Clarkson TB, Melendez GC, Appt SE. Timing hypothesis for postmenopausal hormone therapy: its origin, current status, and future. Menopause. 2013;20(3):342-353.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Instructor, Cardiology

Clinical Interests

Cardiac Disease, Cardiovascular Disease Preventions and Genetics

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