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Akiva Mintz, M.D., Ph.D.Wake Forest School of Medicine

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Akiva Mintz, M.D., Ph.D.

Section Head,
Associate Professor,
Substance Addiction& Abuse Ctr
Office of Research

Clinical Interests

Noninvasive Imaging, Nuclear Medicine Oncologic Imaging, PET/CT, Molecular Imaging

Contact Information

Department: 336-716-2011

Email: amintz@wakehealth.edu

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Education & Training

  • B.A., CUNY Brooklyn College, 1997
  • Ph.D., Penn State University College of Medicine, 2002
  • M.D., Penn State University College of Medicine, 2004
  • Internship, Medicine, Lehigh Valley Hosp Ctr, 2005
  • Fellowship, Nuclear Medicine, University of Pennsylvania, 2008
  • Residency, Nuclear Medicine, Hosp Of The Univ Penn, 2008

Board Certifications

  • American Board of Preventive Medicine, Clinical Informatics
  • American Board of Nuclear Medicine, Nuclear Medicine

Memberships

  • Society of Neuro-Oncology
  • Soc Of Nuclear Medicine
  • Radiological Soc of North Amer

NPI Number

  • 1245389956
Akiva Mintz, M.D., Ph.D.

Doctor Rating

No Rating Available
Why No Ratings?

Akiva Mintz, M.D., Ph.D.

Section Head, Radiology
Associate Professor, Radiology
Substance Addiction& Abuse Ctr
Office of Research

Research Interests

Radiopharmaceuticals; Positron-Emission Tomography; Neoplasms; Tomography, X-Ray Computed; Brain Neoplasms
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Contact Information

Academic: 336-716-4857 | Department: 336-716-2011

Email: amintz@wakehealth.edu

Recent Publications

Novel peripherally derived neural-like stem cells as therapeutic carriers for treating glioblastomas. Birbrair A, Sattiraju A, Zhu D, Zulato G, Batista I, Nguyen VT, Messi ML, Solingapuram Sai KK, Marini FC, Delbono O, Mintz A.. Stem Cells Transl Med. 2017;6(2):471-481.

In vivo evaluation of [18F]FECIMBI-36, an agonist 5-HT2A/2C receptor PET radioligand in nonhuman primate. Prabhakaran J, Solingapuram Sai KK, Zanderigo F, Rubin-Falcone H, Jorgensen MJ, Kaplan JR, Tooke KI, Mintz A, Mann JJ, Kumar JS.. Bioorg Med Chem Lett. 2017;27(1):21-23.

Radiolabeling and initial biological evaluation of [18F]KBM-1 for imaging RAR-alpha receptors in neuroblastoma. Solingapuram Sai KK, Das BC, Sattiraju A, Almaguel FG, Craft S, Mintz A.. Bioorg Med Chem Lett. 2017;27(6):1425-1427.

Association between midlife vascular risk factors and estimated brain amyloid deposition. Gottesman RF, Schneider AL, Zhou Y, Coresh J, Green E, Gupta N, Knopman DS, Mintz A, Rahmim A, Sharrett AR, Wagenknecht LE, Wong DF, Mosley TH.. JAMA. 2017;317(14):1443-1450.

Peptide-based PET imaging of the tumor restricted IL13RA2 biomarker. Sai KK, Sattiraju A, Almaguel FG, Xuan A, Rideout S, Krishnaswamy RS, Zhang J, Herpai DM, Debinski W, Mintz A.. Oncotarget. 2017;():.

Enhancing tissue permeability with MRI guided preclinical focused ultrasound system in rabbit muscle: from normal tissue to VX2 tumor. Sun Y, Xiong X, Pandya D, Jung Y, Mintz A, Hayasaka S, Wadas TJ, Li KCP.. J Control Release. 2017;256():1-8.

How plastic are pericytes?. Birbrair A, Borges IDT, Gilson Sena IF, Almeida GG, da Silva Meirelles L, Goncalves R, Mintz A, Delbono O.. Stem Cells Dev. 2017;():.

Pericytes are heterogeneous in their origin within the same tissue. Dias Moura Prazeres PH, Sena IFG, Borges IDT, de Azevedo PO, Andreotti JP, de Paiva AE, de Almeida VM, de Paula Guerra DA, Pinheiro Dos Santos GS, Mintz A, Delbono O, Birbrair A.. Dev Biol. 2017;427(1):6-11.

Metabolic PET imaging in oncology. Sai KKS, Zachar Z, Bingham PM, Mintz A.. AJR Am J Roentgenol. 2017;():.

Radiosynthesis and evaluation of IGF1R PET ligand [11C]GSK1838705A. Solingapuram Sai KK, Prabhakaran J, Sattiraju A, Mann JJ, Mintz A, Kumar JSD.. Bioorg Med Chem Lett. 2017;27(13):2895-2897.

Phosphatidylserine-targeted nanotheranostics for brain tumor imaging and therapeutic potential. Wang L, Habib AA, Mintz A, Li KC, Zhao D.. Mol Imaging. 2017;16():1-10.

Approach to central nervous system imaging. Mintz A. In: Bennett P, Oza UD, eds. Diagnostic imaging: nuclear medicine. 2nd ed. Philadelphia (PA): Elsevier;2016: 2: 24-25.

CSF leak evaluation. Mintz A, Vasamsetty T. In: Bennett P, Oza UD, eds. Diagnostic imaging: nuclear medicine. 2nd ed. Philadelphia (PA): Elsevier;2016: 2: 26-29.

CSF shunt patency. Mintz A, Vasamsetty T. In: Bennett P, Oza UD, eds. Diagnostic imaging: nuclear medicine. 2nd ed. Philadelphia (PA): Elsevier;2016: 2: 30-33.

Alzheimer disease. Mintz A, Neth BJ. In: Bennett P, Oza UD, eds. Diagnostic imaging: nuclear medicine. 2nd ed. Philadelphia (PA): Elsevier;2016: 2: 38-43.

Frontotemporal dementia. Mintz A, Neth BJ. In: Bennett P, Oza UD, eds. Diagnostic imaging: nuclear medicine. 2nd ed. Philadelphia (PA): Elsevier;2016: 2: 44-47.

Lewy body disease. Mintz A, Neth BJ. In: Bennett P, Oza UD, eds. Diagnostic imaging: nuclear medicine. 2nd ed. Philadelphia (PA): Elsevier;2016: 2: 48-51.

Multi-infarct dementia. Mintz A, Neth BJ, Whitlow CT. In: Bennett P, Oza UD, eds. Diagnostic imaging: nuclear medicine. 2nd ed. Philadelphia (PA): Elsevier;2016: 2: 52-53.

Brain abscess and encephalitis. Mintz A, Bennett P. In: Bennett P, Oza UD, eds. Diagnostic imaging: nuclear medicine. 2nd ed. Philadelphia (PA): Elsevier;2016: 2: 54-55.

Parkinson disease. Mintz A. In: Bennett P, Oza UD, eds. Diagnostic imaging: nuclear medicine. 2nd ed. Philadelphia (PA): Elsevier;2016: 2: 56-59.

Brain death. Mintz A, Vasamsetty T. In: Bennett P, Oza UD, eds. Diagnostic imaging: nuclear medicine. 2nd ed. Philadelphia (PA): Elsevier;2016: 2: 60-63.

Cerebrovascular ischemia. Mintz A, Segovis C. In: Bennett P, Oza UD, eds. Diagnostic imaging: nuclear medicine. 2nd ed. Philadelphia (PA): Elsevier;2016: 2: 64-65.

. Bennett P, Oza UD, Trout AT, Mintz A, eds.. In: Diagnostic imaging: nuclear medicine. 2nd ed. Philadelphia (PA): Elsevier;2016: .

Preliminary therapy evaluation of (225)Ac-DOTA-c(RGDyK) demonstrates that cerenkov radiation derived from (225)Ac daughter decay can be detected by optical imaging for in vivo tumor visualization. Pandya DN, Hantgan R, Budzevich MM, Kock ND, Morse DL, Batista I, Mintz A, Li KC, Wadas TJ.. Theranostics. 2016;6(5):698-709.

ACRIN 6684: assessment of tumor hypoxia in newly diagnosed glioblastoma using 18F-FMISO PET and MRI. Gerstner E, Zhang Z, Fink J, Muzi M, Hanna L, Greco E, Prah M, Schmainda K, Mintz A, Kostakoglu L, Eikman EA, Ellingson BM, Ratai EM, Sorensen AG, Barboriak D, Mankoff DA.. Clin Cancer Res. 2016;22(20):5079-5086.

Regulation of brachyury by fibroblast growth factor receptor 1 in lung cancer. Hu Y, Feng X, Mintz A, Jeffrey Petty W, Hsu W.. Oncotarget. 2016;7(52):87124-35.

Liposome-protamine-DNA nanoparticle-mediated delivery of short hairpin RNA targeting brachyury inhibits chordoma cell growth. Hu YP, Singh R, Deng ZY, Mintz A, Hsu W.. J Biomed Nanotechnol. 2016;12(10):1952-1961.

Targeted liposomes with gadolinium are more sensitive and more specific for tumor detection than magnevist [abstract]. Liu X, Madhankumar AB, Miller P, Webb B, Mintz A, Yang Q, Connor J.. Neuro Oncol. 2016;18(Suppl 6):50.

Pericytes at the intersection between tissue regeneration and pathology. Birbrair A, Zhang T, Wang ZM, Messi ML, Mintz A, Delbono O.. Clin Sci (Lond). 2015;128(2):81-93.

Pseudoaneurysm of a pancreas allograft artery detected by 99mTc red blood cell SPECT/CT. Tamam M, Mintz A.. Clin Nucl Med. 2015;40(4):e241-e244.

ACRIN 6684: assessment of tumor hypoxia in newly diagnosed GBM using FMISO PET and MRI [abstract]. Gerstner ER, Zhang Z, Fink JR, Muzi M, Hanna L, Greco E, Mintz A, Kostakoglu L, Eikman EA, Prah M, Schmainda KM, Sorensen GA, Barboriak D, Mankoff DA.. J Clin Oncol. 2015;33(15 Suppl):2024.

Remote spatiotemporally controlled and biologically selective permeabilization of blood-brain barrier. Xiong X, Sun Y, Sattiraju A, Jung Y, Mintz A, Hayasaka S, Li KC.. J Control Release. 2015;217():113-120.

Permeabilizing the blood-brain-barrier with alpha-particle therapy [abstract]. Sattiraju A, Xiong XB, Pandya D, Sun Y, Jung Y, Wadas T, Li K, Mintz A.. J Nucl Med. 2015;56(3 Suppl 3):1230.

Improved automated radiosynthesis of [(11)C]PBR28. Sai KKS, Gage D, Nader M, Mach RH, Mintz A.. Sci Pharm. 2015;83(3):413-427.

Type-2 pericytes participate in normal and tumoral angiogenesis. Birbrair A, Zhang T, Wang ZM, Messi ML, Olson JD, Mintz A, Delbono O.. Am J Physiol Cell Physiol. 2014;307(1):C25-C38.

Molecular targeted alpha-particle therapy for oncologic applications. Wadas TJ, Pandya DN, Solingapuram Sai KK, Mintz A.. AJR Am J Roentgenol. 2014;203(2):253-260.

Pericytes: multitasking cells in the regeneration of injured, diseased, and aged skeletal muscle. Birbrair A, Zhang T, Wang ZM, Messi ML, Mintz A, Delbono O.. Front Aging Neurosci. 2014;6():245.

Type-1 pericytes accumulate after tissue injury and produce collagen in an organ-dependent manner. Birbrair A, Zhang T, Files DC, Mannava S, Smith T, Wang ZM, Messi ML, Mintz A, Delbono O.. Stem Cell Res Ther. 2014;5(6):122.

Therapeutic potential of a newly discovered neural like stem cell [abstract]. Sattiraju A, Birbrair A, Zhu D, Batista I, Delbono O, Mintz A.. Neuro Oncol. 2014;16(Suppl 5):v203.

Skeletal muscle neural progenitor cells exhibit properties of NG2-glia. Birbrair A, Zhang T, Wang ZM, Messi ML, Enikolopov GN, Mintz A, Delbono O.. Exp Cell Res. 2013;319(1):45-63.

Skeletal muscle pericyte subtypes differ in their differentiation potential. Birbrair A, Zhang T, Wang Z-M, Messi ML, Enikolopov GN, Mintz A, Delbono O.. Stem Cell Res. 2013;10(1):67-84.

PET/CT illustration of metastatic breast cancer to the left mandibular foramen. Kota G, Gupta P, Mintz A.. Clin Nucl Med. 2013;38(5):385-386.

The potential of 11C-acetate PET for monitoring the fatty acid synthesis pathway in tumors. Deford-Watts LM, Mintz A, Kridel SJ.. Curr Pharm Biotechnol. 2013;14(3):300-312.

Role of pericytes in skeletal muscle regeneration and fat accumulation. Birbrair A, Zhang T, Wang ZM, Messi ML, Enikolopov GN, Mintz A, Delbono O.. Stem Cells Dev. 2013;22(16):2298-2314.

Somatostatin receptor molecular imaging for metastatic intracranial hemangiopericytoma. Kota G, Gupta P, Lesser GJ, Wilson JA, Mintz A.. Clin Nucl Med. 2013;38(12):984-987.

Type-1 pericytes participate in fibrous tissue deposition in aged skeletal muscle. Birbrair A, Zhang T, Wang ZM, Messi ML, Mintz A, Delbono O.. Am J Physiol Cell Physiol. 2013;305(11):C1098-1113.

Changes in FDG-PET uptake during a delayed match to samplememory task [abstract]. Linville C, Mintz A, Hampson R, Deadwyler S, Peiffer A.. Neuro Oncol. 2013;15(Suppl 3):95.

Therapeutic efficacy of an optimized quadruply mutated IL13-based bacterial cytotoxin in an orthotopic murine glioma model [abstract]. Nguyen V, Zhu D, Conyers JM, Debinski W, Mintz A.. Cancer Res. 2013;73(8 Suppl 1):A2150.

Evolution of a ureteric stone from the renal pelvis to the ureter on skeletal scintigraphy with CT correlation. Gupta P, Kota G, Mintz A.. Clin Nucl Med. 2012;37(2):188-189.

EphrinA1 is released in three forms from cancer cells by matrix metalloproteases. Beauchamp A, Lively MO, Mintz A, Gibo D, Wykosky J, Debinski W.. Mol Cell Biol. 2012;32(16):3253-3264.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Associate Professor, Radiology

Clinical Interests

Noninvasive Imaging, Nuclear Medicine Oncologic Imaging, PET/CT, Molecular Imaging
Akiva Mintz, M.D., Ph.D.

Akiva Mintz, M.D., Ph.D.

Section Head, Radiology
Associate Professor, Radiology
Substance Addiction& Abuse Ctr
Office of Research

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