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Akiva Mintz, M.D., Ph.D.Wake Forest School of Medicine

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Akiva Mintz, M.D., Ph.D.

Section Head,
Associate Professor,
Office of Research

Clinical Interests

Noninvasive Imaging, Nuclear Medicine Oncologic Imaging, PET/CT, Molecular Imaging

Contact Information

Department: 336-716-2011

Email: amintz@wakehealth.edu

Insurance Accepted »

Education & Training

  • B.A., CUNY Brooklyn College, 1997
  • Ph.D., Penn State University College of Medicine, 2002
  • M.D., Penn State University College of Medicine, 2004
  • Internship, Medicine, Lehigh Valley Hosp Ctr, 2005
  • Fellowship, Nuclear Medicine, University of Pennsylvania, 2008
  • Residency, Nuclear Medicine, Hosp Of The Univ Penn, 2008

Board Certifications

  • American Board of Nuclear Medicine, Nuclear Medicine

Memberships

  • Society of Neuro-Oncology
  • Soc Of Nuclear Medicine
  • Radiological Soc of North Amer

NPI Number

  • 1245389956
Akiva Mintz, M.D., Ph.D.

Doctor Rating

No Rating Available
Why No Ratings?

Akiva Mintz, M.D., Ph.D.

Section Head, Radiology
Associate Professor, Radiology
Office of Research

Research Interests

Neoplasms; Brain Neoplasms; Radiopharmaceuticals; Xenograft Model Antitumor Assays; Interleukin-13
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Contact Information

Academic: 336-716-4857 | Department: 336-716-2011

Email: amintz@wakehealth.edu

Recent Publications

Approach to central nervous system imaging. Mintz A. In: Bennett P, Oza UD, eds. Diagnostic imaging: nuclear medicine. 2nd ed. Philadelphia (PA): Elsevier;2016: 2: 24-25.

CSF leak evaluation. Mintz A, Vasamsetty T. In: Bennett P, Oza UD, eds. Diagnostic imaging: nuclear medicine. 2nd ed. Philadelphia (PA): Elsevier;2016: 2: 26-29.

CSF shunt patency. Mintz A, Vasamsetty T. In: Bennett P, Oza UD, eds. Diagnostic imaging: nuclear medicine. 2nd ed. Philadelphia (PA): Elsevier;2016: 2: 30-33.

Alzheimer disease. Mintz A, Neth BJ. In: Bennett P, Oza UD, eds. Diagnostic imaging: nuclear medicine. 2nd ed. Philadelphia (PA): Elsevier;2016: 2: 38-43.

Frontotemporal dementia. Mintz A, Neth BJ. In: Bennett P, Oza UD, eds. Diagnostic imaging: nuclear medicine. 2nd ed. Philadelphia (PA): Elsevier;2016: 2: 44-47.

Lewy body disease. Mintz A, Neth BJ. In: Bennett P, Oza UD, eds. Diagnostic imaging: nuclear medicine. 2nd ed. Philadelphia (PA): Elsevier;2016: 2: 48-51.

Multi-infarct dementia. Mintz A, Neth BJ, Whitlow CT. In: Bennett P, Oza UD, eds. Diagnostic imaging: nuclear medicine. 2nd ed. Philadelphia (PA): Elsevier;2016: 2: 52-53.

Brain abscess and encephalitis. Mintz A, Bennett P. In: Bennett P, Oza UD, eds. Diagnostic imaging: nuclear medicine. 2nd ed. Philadelphia (PA): Elsevier;2016: 2: 54-55.

Parkinson disease. Mintz A. In: Bennett P, Oza UD, eds. Diagnostic imaging: nuclear medicine. 2nd ed. Philadelphia (PA): Elsevier;2016: 2: 56-59.

Brain death. Mintz A, Vasamsetty T. In: Bennett P, Oza UD, eds. Diagnostic imaging: nuclear medicine. 2nd ed. Philadelphia (PA): Elsevier;2016: 2: 60-63.

Cerebrovascular ischemia. Mintz A, Segovis C. In: Bennett P, Oza UD, eds. Diagnostic imaging: nuclear medicine. 2nd ed. Philadelphia (PA): Elsevier;2016: 2: 64-65.

. Bennett P, Oza UD, Trout AT, Mintz A, eds.. In: Diagnostic imaging: nuclear medicine. 2nd ed. Philadelphia (PA): Elsevier;2016: .

Preliminary therapy evaluation of (225)Ac-DOTA-c(RGDyK) demonstrates that cerenkov radiation derived from (225)Ac daughter decay can be detected by optical imaging for in vivo tumor visualization. Pandya DN, Hantgan R, Budzevich MM, Kock ND, Morse DL, Batista I, Mintz A, Li KC, Wadas TJ.. Theranostics. 2016;6(5):698-709.

ACRIN 6684: assessment of tumor hypoxia in newly diagnosed glioblastoma using 18F-FMISO PET and MRI. Gerstner E, Zhang Z, Fink J, Muzi M, Hanna L, Greco E, Prah M, Schmainda K, Mintz A, Kostakoglu L, Eikman EA, Ellingson BM, Ratai EM, Sorensen AG, Barboriak D, Mankoff DA.. Clin Cancer Res. 2016;22(20):5079-5086.

Novel peripherally derived neural-like stem cells as therapeutic carriers for treating glioblastomas. Birbrair A, Sattiraju A, Zhu D, Zulato G, Batista I, Nguyen VT, Messi ML, Solingapuram Sai KK, Marini FC, Delbono O, Mintz A.. Stem Cells Transl Med. 2016;():.

Pericytes at the intersection between tissue regeneration and pathology. Birbrair A, Zhang T, Wang ZM, Messi ML, Mintz A, Delbono O.. Clin Sci (Lond). 2015;128(2):81-93.

Pseudoaneurysm of a pancreas allograft artery detected by 99mTc red blood cell SPECT/CT. Tamam M, Mintz A.. Clin Nucl Med. 2015;40(4):e241-e244.

ACRIN 6684: assessment of tumor hypoxia in newly diagnosed GBM using FMISO PET and MRI [abstract]. Gerstner ER, Zhang Z, Fink JR, Muzi M, Hanna L, Greco E, Mintz A, Kostakoglu L, Eikman EA, Prah M, Schmainda KM, Sorensen GA, Barboriak D, Mankoff DA.. J Clin Oncol. 2015;33(15 Suppl):2024.

Remote spatiotemporally controlled and biologically selective permeabilization of blood-brain barrier. Xiong X, Sun Y, Sattiraju A, Jung Y, Mintz A, Hayasaka S, Li KC.. J Control Release. 2015;217():113-120.

Permeabilizing the blood-brain-barrier with alpha-particle therapy [abstract]. Sattiraju A, Xiong XB, Pandya D, Sun Y, Jung Y, Wadas T, Li K, Mintz A.. J Nucl Med. 2015;56(3 Suppl 3):1230.

Improved automated radiosynthesis of [(11)C]PBR28. Sai KKS, Gage D, Nader M, Mach RH, Mintz A.. Sci Pharm. 2015;83(3):413-427.

Type-2 pericytes participate in normal and tumoral angiogenesis. Birbrair A, Zhang T, Wang ZM, Messi ML, Olson JD, Mintz A, Delbono O.. Am J Physiol Cell Physiol. 2014;307(1):C25-C38.

Molecular targeted alpha-particle therapy for oncologic applications. Wadas TJ, Pandya DN, Solingapuram Sai KK, Mintz A.. AJR Am J Roentgenol. 2014;203(2):253-260.

Pericytes: multitasking cells in the regeneration of injured, diseased, and aged skeletal muscle. Birbrair A, Zhang T, Wang ZM, Messi ML, Mintz A, Delbono O.. Front Aging Neurosci. 2014;6():245.

Type-1 pericytes accumulate after tissue injury and produce collagen in an organ-dependent manner. Birbrair A, Zhang T, Files DC, Mannava S, Smith T, Wang ZM, Messi ML, Mintz A, Delbono O.. Stem Cell Res Ther. 2014;5(6):122.

Therapeutic potential of a newly discovered neural like stem cell [abstract]. Sattiraju A, Birbrair A, Zhu D, Batista I, Delbono O, Mintz A.. Neuro Oncol. 2014;16(Suppl 5):v203.

Skeletal muscle neural progenitor cells exhibit properties of NG2-glia. Birbrair A, Zhang T, Wang ZM, Messi ML, Enikolopov GN, Mintz A, Delbono O.. Exp Cell Res. 2013;319(1):45-63.

Skeletal muscle pericyte subtypes differ in their differentiation potential. Birbrair A, Zhang T, Wang Z-M, Messi ML, Enikolopov GN, Mintz A, Delbono O.. Stem Cell Res. 2013;10(1):67-84.

PET/CT illustration of metastatic breast cancer to the left mandibular foramen. Kota G, Gupta P, Mintz A.. Clin Nucl Med. 2013;38(5):385-386.

The potential of 11C-acetate PET for monitoring the fatty acid synthesis pathway in tumors. Deford-Watts LM, Mintz A, Kridel SJ.. Curr Pharm Biotechnol. 2013;14(3):300-312.

Role of pericytes in skeletal muscle regeneration and fat accumulation. Birbrair A, Zhang T, Wang ZM, Messi ML, Enikolopov GN, Mintz A, Delbono O.. Stem Cells Dev. 2013;22(16):2298-2314.

Somatostatin receptor molecular imaging for metastatic intracranial hemangiopericytoma. Kota G, Gupta P, Lesser GJ, Wilson JA, Mintz A.. Clin Nucl Med. 2013;38(12):984-987.

Type-1 pericytes participate in fibrous tissue deposition in aged skeletal muscle. Birbrair A, Zhang T, Wang ZM, Messi ML, Mintz A, Delbono O.. Am J Physiol Cell Physiol. 2013;305(11):C1098-1113.

Changes in FDG-PET uptake during a delayed match to samplememory task [abstract]. Linville C, Mintz A, Hampson R, Deadwyler S, Peiffer A.. Neuro Oncol. 2013;15(Suppl 3):95.

Therapeutic efficacy of an optimized quadruply mutated IL13-based bacterial cytotoxin in an orthotopic murine glioma model [abstract]. Nguyen V, Zhu D, Conyers JM, Debinski W, Mintz A.. Cancer Res. 2013;73(8 Suppl 1):A2150.

Evolution of a ureteric stone from the renal pelvis to the ureter on skeletal scintigraphy with CT correlation. Gupta P, Kota G, Mintz A.. Clin Nucl Med. 2012;37(2):188-189.

EphrinA1 is released in three forms from cancer cells by matrix metalloproteases. Beauchamp A, Lively MO, Mintz A, Gibo D, Wykosky J, Debinski W.. Mol Cell Biol. 2012;32(16):3253-3264.

A novel ligand delivery system to non-invasively visualize and therapeutically exploit the IL13R alpha2 tumor-restricted biomarker. Nguyen V, Conyers JM, Zhu D, Gibo DM, Hantgan RR, Larson SM, Debinski W, Mintz A.. Neuro Oncol. 2012;14(10):1239-1253.

Metastatic intracranial hemangiopericytoma: the role of octreotide and PET imaging in diagnosis, pre-treatment and follow-up evaluation [abstract]. Kota G, Gupta P, Wilson J, Lesser G, Mintz A.. J Nucl Med. 2011;52(Suppl 1):abstr 1065.

Unilateral diffusely increased muscle uptake of F-18 FDG in a patient with hemiparesis due to stroke. Gupta P, Kota G, Alavi A, Mintz A.. Clin Nucl Med. 2011;36(12):1140-1141.

IL-13R alpha2-targeted therapy escapees: biologic and therapeutic implications. Nguyen V, Conyers JM, Zhu D, Gibo DM, Dorsey JF, Debinski W, Mintz A.. Transl Oncol. 2011;4(6):390-400.

Pretargeting the masses: a means of improving and mainstreaming targeted molecular delivery? [commentary]. Nguyen V, Conyers JM, Mintz A.. Cancer Biol Ther. 2010;10(8):775-779.

Targeting angiogenesis in an age of personalized medicine [commentary]. Kota GK, Gupta P, Conyers JM, Mintz A.. Cancer Biol Ther. 2010;10(9):874-877.

Phase II study of monthly pasireotide LAR (Som230C) for recurrent or progressive meningioma [abstract]. Hammond SN, Norden AD, Drappatz J, Phuphanich S, Reardon D, Wong ET, Plotkin SR, Lesser G, Mintz A, Raizer JJ, et al.. Neuro Oncol. 2010;12(Suppl 4):71.

Combinatorial targeting of EphA2 and IL-13Ralpha2 GBM-restricted biomarkers [abstract]. Nguyen V, Murphy LT, Beauchamp AS, Hollingsworth CK, Debinski W, Mintz A.. Neuro Oncol. 2010;12(Suppl 4):97.

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and paclitaxel have cooperative in vivo effects against glioblastoma multiforme cells. Dorsey JF, Mintz A, Tian X, Dowling ML, Plastaras JP, Dicker DT, Kao GD, El-Deiry WS.. Mol Cancer Ther. 2009;8(12):3285-3295.

New frontiers in biomarker-targeted molecular imaging [commentary]. Nguyen V, Mintz A.. Cancer Biol Ther. 2009;8(23):2235-2238.

Protein- and DNA-based active immunotherapy targeting interleukin-13 receptor alpha2. Mintz A, Gibo DM, MadhanKumar AB, Cladel NM, Christensen ND, Debinski W.. Cancer Biother Radiopharm. 2008;23(5):581-589.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Associate Professor, Radiology

Clinical Interests

Noninvasive Imaging, Nuclear Medicine Oncologic Imaging, PET/CT, Molecular Imaging
Akiva Mintz, M.D., Ph.D.

Akiva Mintz, M.D., Ph.D.

Section Head, Radiology
Associate Professor, Radiology
Office of Research

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