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Research

Nilamadhab Mishra, M.D.

Associate Professor, Rheumatology and Immunology
Comprehensive Cancer Center
Physiology & Pharmacology

Clinical Specialties

Systemic Lupus Erythematosus, Sjogren's Syndrome, Rheumatoid Arthritis

Contact Information

New Patient Appointments: 336-716-WAKE
Returning Patient Appointments: 336-716-4209
Department: 336-716-4209

Insurance Accepted »

Education & Training

M.B.,B.S., M.K.C.G. Medical College, Berhampur, Orissa , 1989
B.Sc., Free Standing Institute-India , 1983
Fellowship, Delhi University College Medical Sciences-India, 1996
Fellowship, WFU School of Medicine, 2001

NPI Number

1104801232

Nilamadhab Mishra, M.D.

Associate Professor, Rheumatology and Immunology Comprehensive Cancer Center
Physiology & Pharmacology

Research Interests

arthritis, immunology/allergy/inflammatio, minority health issues, women's health issues

Contact Information

Academic: 336-716-6573 | Department: 336-716-4209

Recent Publications

Rong S, Cao Q, Liu M, Seo J, Jia L, Boudyguina E, Gebre AK, Colvin PL, Smith TL, Murphy RC, Mishra N, Parks JS. Macrophage 12/15 lipoxygenase expression increases plasma and hepatic lipid levels and exacerbates atherosclerosis. J Lipid Res. 2012;53(4):686-695.

Reilly CM, Regna N, Mishra N. HDAC inhibition in lupus models. Mol Med. 2011;17(5-6):417-425.

Yan K, Cao Q, Reilly CM, Young NL, Garcia BA, Mishra N. Histone deacetylase 9 deficiency protects against effector T cell-mediated systemic autoimmunity. J Biol Chem. 2011;286(33):28833-43.

Burger KL, Davis AL, Isom S, Mishra N, Seals DF. The podosome marker protein Tks5 regulates macrophage invasive behavior. Cytoskeleton (Hoboken). 2011;68(12):694-711.

Hodges SJ, Yoo JJ, Mishra N, Atala A. The effect of epigenetic therapy on congenital neurogenic bladders--a pilot study. Urology. 2010;75(4):868-872.

Vachharajani V, Wang SW, Mishra N, El Gazzar M, Yoza B, McCall C. Curcumin modulates leukocyte and platelet adhesion in murine sepsis. Microcirculation. 2010;17(6):407-416.

Kalin Y, Qiang C, Reilly CM, Cann JA, Rhonda BD, Olson EN, Garcia B, Mishra NA. An epigenetic switch involving chromatin modifier HDAC9 in T cells links to lupus pathogenesis in MRL/Ipr mice [abstract]. J Dermatol. 2010;37(Suppl 1):35.

Mehta J, Genin A, Brunner M, Scalzi LV, Mishra N, Beukelman T, Cron RQ. Prolonged expression of CD154 on CD4 T cells from pediatric lupus patients correlates with increased CD154 transcription, increased nuclear factor of activated T cell activity, and glomerulonephritis. Arthritis Rheum. 2010;62(8):2499-2509.

Furie R, Stohl W, Ginzler EM, Becker M, Mishra N, Chatham W, Merrill JT, Weinstein A, McCune WJ, Zhong J, et al. Biologic activity and safety of belimumab, a neutralizing anti-B-lymphocyte stimulator (BLyS) monoclonal antibody: a phase I trial in patients with systemic lupus erythematosus. Arthritis Res Ther. 2009;10(5):art. R109.

Burger KL, Mishra N, Seals D. Tks5 and macrophage podosome formation [abstract]. Clin Exp Metastasis. 2009;26(7):869.

Mishra N, Hammer G, inventors; Wake Forest University Health Sciences, assignee. Method of treating immune diseases. United States patent US 7,557,141. 2009 July 7. 2009;():.

Lu X, Kovalev GI, Chang H, Kallin E, Knudsen G, Xia L, Mishra N, Ruiz P, Li E, Su L, Zhang Y. Inactivation of NuRD component Mta2 causes abnormal T cell activation and lupus-like autoimmune disease in mice. J Biol Chem. 2008;283(20):13825-33.

Zhu X, Lee J-Y, Timmins JM, Brown JM, Boudyguina E, Mulya A, Gebre AK, Willingham MC, Mishra N, Parks JS, et al. Increased cellular free cholesterol in macrophage-specific Abca1 knock-out mice enhances pro-inflammatory response of macrophages. J Biol Chem. 2008;283(34):22930-41.

Sodhi R, Mishra N. Selective toll-like receptor agonist combinations synergistically trigger inflammatory mediators in macrophages, which can be inhibited by histone deacetylase inhibition [abstract]. Arthritis Rheum. 2008;58(9 Suppl):S185.

Reilly CM, Thomas M, Gogal R Jr, Olgun S, Santo A, Sodhi R, Samy ET, Peng SL, Gilkeson GS, Mishra N. The histone deacetylase inhibitor trichostatin A upregulates regulatory T cells and modulates autoimmunity in NZB/W F1 mice. J Autoimmun. 2008;31(2):123-130.

Garcia BA, Hake SB, Diaz RL, Kauer M, Morris SA, Recht J, Shabanowitz J, Mishra N, Strahl BD, Allis CD, Hunt DF. Organismal differences in post-translational modifications in histones H3 and H4. J Biol Chem. 2007;282(10):7641-7655.

Kammer GD, Mishra N, inventors; Wake Forest University Health Sciences, assignee. Method of treating autoimmune disease. United States patent US 7,271,198. 2007 Sept 18. 2007;():.

Atwood T, Carter C, Zhu JM, Mishra N. Monitoring neuropsychiatric symptoms in Mrl/lpr lupus mouse model with proton magnetic resonance spectroscope [abstract]. Arthritis Rheum. 2006;54(9):S622.

Mishra N, Keiger K, Labourier E. MicroRNA signature in human lupus [abstract]. Arthritis Rheum. 2006;54(9 Suppl):S753.

Mishra N, Keiger K, Labourier E. Microrna, innate immunity and lupus [abstract]. Arthritis Rheum. 2006;54(9 Suppl):S39.

Mishra N, Parks J, Rankin C, Clair R. Histone deacetylase inhibitors decrease macrophage foam cell formation and stabilize atherosclerotic plaques by multiple mechanisms [abstract]. Arthritis Rheum. 2006;54(9 Suppl):S580.

Snowhite I, Mishra N. Histone hypermethylation is an indicator of epigenetic plasticity in activated B lymphocytes [abstract]. Arthritis Rheum. 2006;54(9 Suppl):S41.

Snowhite I, Mishra N. Histone hypermethylation is an indicator of epigenetic plasticity in activated B lymphocytes [abstract]. Arthritis Rheum. 2006;54(9 Suppl):S69.