Profile

Nilamadhab Mishra, M.D.Wake Forest School of Medicine

Nilamadhab Mishra, M.D.

Associate Professor,


Clinical Interests

Rheumatoid Arthritis, Sjogren's Syndrome, Systemic Lupus Erythematosus

Contact Information

Academic: 336-716-4209 | Department: 336-716-4209

Education & Training

  • B.Sc., Free Standing Institute-India, 1983
  • M.B.,B.S., M.K.C.G. Medical College, Berhampur, Orissa, 1989
  • Fellowship, Delhi University College Medic, 1996
  • Fellowship, WFU School of Medicine, 2001

NPI Number

  • 1104801232
Nilamadhab Mishra, M.D.

Nilamadhab Mishra, M.D.

Associate Professor, Rheumatology and Immunology
Comprehensive Cancer Center
Physiology & Pharmacology

Research Interests

immunology/allergy/inflammatio

Contact Information

Academic: 336-716-4209 | Department: 336-716-4209

Recent Publications

Cao Q, Rong S, Repa JJ, Clair RS, Parks JS, Mishra N. Histone deacetylase 9 represses cholesterol efflux and alternatively activated macrophages in atherosclerosis development. Arterioscler Thromb Vasc Biol. 2014;34(9):1871-1879.

Sridharan R, Gonzales-Cope M, Chronis C, Bonora G, McKee R, Huang C, Patel S, Lopez D, Mishra N, Pellegrini M, Carey M, Garcia BA, Plath K. Proteomic and genomic approaches reveal critical functions of H3K9 methylation and heterochromatin protein-1 gamma in reprogramming to pluripotency. Nat Cell Biol. 2013;15(7):872-882.

Rong S, Cao Q, Liu M, Seo J, Jia L, Boudyguina E, Gebre AK, Colvin PL, Smith TL, Murphy RC, Mishra N, Parks JS. Macrophage 12/15 lipoxygenase expression increases plasma and hepatic lipid levels and exacerbates atherosclerosis. J Lipid Res. 2012;53(4):686-695.

Reilly CM, Regna N, Mishra N. HDAC inhibition in lupus models. Mol Med. 2011;17(5-6):417-425.

Yan K, Cao Q, Reilly CM, Young NL, Garcia BA, Mishra N. Histone deacetylase 9 deficiency protects against effector T cell-mediated systemic autoimmunity. J Biol Chem. 2011;286(33):28833-43.

Burger KL, Davis AL, Isom S, Mishra N, Seals DF. The podosome marker protein Tks5 regulates macrophage invasive behavior. Cytoskeleton (Hoboken). 2011;68(12):694-711.

Hodges SJ, Yoo JJ, Mishra N, Atala A. The effect of epigenetic therapy on congenital neurogenic bladders--a pilot study. Urology. 2010;75(4):868-872.

Vachharajani V, Wang SW, Mishra N, El Gazzar M, Yoza B, McCall C. Curcumin modulates leukocyte and platelet adhesion in murine sepsis. Microcirculation. 2010;17(6):407-416.

Kalin Y, Qiang C, Reilly CM, Cann JA, Rhonda BD, Olson EN, Garcia B, Mishra NA. An epigenetic switch involving chromatin modifier HDAC9 in T cells links to lupus pathogenesis in MRL/Ipr mice [abstract]. J Dermatol. 2010;37(Suppl 1):35.

Mehta J, Genin A, Brunner M, Scalzi LV, Mishra N, Beukelman T, Cron RQ. Prolonged expression of CD154 on CD4 T cells from pediatric lupus patients correlates with increased CD154 transcription, increased nuclear factor of activated T cell activity, and glomerulonephritis. Arthritis Rheum. 2010;62(8):2499-2509.

Furie R, Stohl W, Ginzler EM, Becker M, Mishra N, Chatham W, Merrill JT, Weinstein A, McCune WJ, Zhong J, et al. Biologic activity and safety of belimumab, a neutralizing anti-B-lymphocyte stimulator (BLyS) monoclonal antibody: a phase I trial in patients with systemic lupus erythematosus. Arthritis Res Ther. 2009;10(5):art. R109.

Burger KL, Mishra N, Seals D. Tks5 and macrophage podosome formation [abstract]. Clin Exp Metastasis. 2009;26(7):869.

Mishra N, Hammer G, inventors; Wake Forest University Health Sciences, assignee. Method of treating immune diseases. United States patent US 7,557,141. 2009 July 7. 2009;():.

Lu X, Kovalev GI, Chang H, Kallin E, Knudsen G, Xia L, Mishra N, Ruiz P, Li E, Su L, Zhang Y. Inactivation of NuRD component Mta2 causes abnormal T cell activation and lupus-like autoimmune disease in mice. J Biol Chem. 2008;283(20):13825-33.

Zhu X, Lee J-Y, Timmins JM, Brown JM, Boudyguina E, Mulya A, Gebre AK, Willingham MC, Mishra N, Parks JS, et al. Increased cellular free cholesterol in macrophage-specific Abca1 knock-out mice enhances pro-inflammatory response of macrophages. J Biol Chem. 2008;283(34):22930-41.

Sodhi R, Mishra N. Selective toll-like receptor agonist combinations synergistically trigger inflammatory mediators in macrophages, which can be inhibited by histone deacetylase inhibition [abstract]. Arthritis Rheum. 2008;58(9 Suppl):S185.

Reilly CM, Thomas M, Gogal R Jr, Olgun S, Santo A, Sodhi R, Samy ET, Peng SL, Gilkeson GS, Mishra N. The histone deacetylase inhibitor trichostatin A upregulates regulatory T cells and modulates autoimmunity in NZB/W F1 mice. J Autoimmun. 2008;31(2):123-130.

Garcia BA, Hake SB, Diaz RL, Kauer M, Morris SA, Recht J, Shabanowitz J, Mishra N, Strahl BD, Allis CD, Hunt DF. Organismal differences in post-translational modifications in histones H3 and H4. J Biol Chem. 2007;282(10):7641-7655.

Kammer GD, Mishra N, inventors; Wake Forest University Health Sciences, assignee. Method of treating autoimmune disease. United States patent US 7,271,198. 2007 Sept 18. 2007;():.

Atwood T, Carter C, Zhu JM, Mishra N. Monitoring neuropsychiatric symptoms in Mrl/lpr lupus mouse model with proton magnetic resonance spectroscope [abstract]. Arthritis Rheum. 2006;54(9):S622.

Mishra N, Keiger K, Labourier E. MicroRNA signature in human lupus [abstract]. Arthritis Rheum. 2006;54(9 Suppl):S753.

Mishra N, Keiger K, Labourier E. Microrna, innate immunity and lupus [abstract]. Arthritis Rheum. 2006;54(9 Suppl):S39.

Mishra N, Parks J, Rankin C, Clair R. Histone deacetylase inhibitors decrease macrophage foam cell formation and stabilize atherosclerotic plaques by multiple mechanisms [abstract]. Arthritis Rheum. 2006;54(9 Suppl):S580.

Snowhite I, Mishra N. Histone hypermethylation is an indicator of epigenetic plasticity in activated B lymphocytes [abstract]. Arthritis Rheum. 2006;54(9 Suppl):S41.

Snowhite I, Mishra N. Histone hypermethylation is an indicator of epigenetic plasticity in activated B lymphocytes [abstract]. Arthritis Rheum. 2006;54(9 Suppl):S69.

Sodhi R, Mishra N. Selective toll-like receptor agonist combinations synergistically trigger inflammatory mediators in macrophages, which can be inhibited by histone deacetylase inhibition [abstract]. Arthritis Rheum. 2006;54(9 Suppl):S43.

Sodhi R, Mishra N. Selective toll-like receptor agonist combinations synergistically trigger inflammatory mediators in macrophages, which can be inhibited by histone deacetylase inhibition [abstract]. Arthritis Rheum. 2006;54(9 Suppl):S635.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Associate Professor, Rheumatology and Immunology

Clinical Interests

Rheumatoid Arthritis, Sjogren's Syndrome, Systemic Lupus Erythematosus

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