Skeletal muscle mitochondrial content, oxidative capacity, and Mfn2 expression are reduced in older patients with heart failure and preserved ejection fraction and are related to exercise intolerance. Molina AJ, Bharadwaj MS, Van Horn C, Nicklas BJ, Lyles MF, Eggebeen J, Haykowsky MJ, Brubaker PH, Kitzman DW.. JACC Heart Fail. 2016;4(8):636-645.
Respirometric profiling of muscle mitochondria and blood cells are associated with differences in gait speed among community-dwelling older adults. Tyrrell DJ, Bharadwaj MS, Van Horn CG, Kritchevsky SB, Nicklas BJ, Molina AJ.. J Gerontol A Biol Sci Med Sci. 2015;70(11):1394-1399.
Sequential actions of SIRT1-RELB-SIRT3 coordinate nuclear-mitochondrial communication during immunometabolic adaptation to acute inflammation and sepsis. Liu TF, Vachharajani V, Millet P, Bharadwaj MS, Molina AJ, McCall CE.. J Biol Chem. 2015;290(1):396-408.
Energy metabolism in a matched model of radiation resistance for head and neck squamous cell cancer. Mims J, Bansal N, Bharadwaj MS, Chen X, Molina AJ, Tsang AW, Furdui CM.. Radiat Res. 2015;183(3):291-304.
Preparation and respirometric assessment of mitochondria isolated from skeletal muscle tissue obtained by percutaneous needle biopsy [video article]. Bharadwaj MS, Tyrrell DJ, Lyles MF, Demons JL, Rogers GW, Molina AJ.. J Vis Exp. 2015;(96):e52350.
Blood-cell bioenergetics are associated with physical function and inflammation in overweight/obese older adults. Tyrrell DJ, Bharadwaj MS, Van Horn CG, Marsh AP, Nicklas BJ, Molina AJ.. Exp Gerontol. 2015;70():84-91.
Relationships between mitochondrial content and bioenergetics with obesity, body composition and fat distribution in healthy older adults. Bharadwaj MS, Tyrrell DJ, Leng I, Demons JL, Lyles MF, Carr JJ, Nicklas BJ, Molina AJ.. BMC Obes. 2015;2():40.
Mitochondrial bioenergetics, inflammation, and physical ability in older adults [abstract]. Molina AJ, Tyrrell DJ, Bharadwaj MS, Van Horn CG, Marsh A, Nicklas B.. Gerontologist. 2015;55(Suppl 2):733.
Relationships between blood bioenergetic capacity and fat loss after diet and exercise intervention [abstract]. Tyrrell DJ, Bharadwaj MS, Van Horn CG, Nicklas B, Molina AJ.. Gerontologist. 2015;55(Suppl 2):163.
Examination of bioenergetic function in the inner mitochondrial membrane peptidase 2-like (Immp2l) mutant mice. Bharadwaj MS, Zhou Y, Molina AJ, Criswell T, Lu B.. Redox Biol. 2014;2():1008-1015.
Bactericidal antibiotics induce mitochondrial dysfunction and oxidative damage in mammalian cells. Kalghatgi S, Spina CS, Costello JC, Liesa M, Morones-Ramirez JR, Slomovic S, Molina A, Shirihai OS, Collins JJ.. Sci Transl Med. 2013;5(192):192ra85.
Obesity is accompanied by increased basal mitochondrial respiration in older adults [abstract]. Bharadwaj MS, Nicklas B, Molina AJ.. Gerontologist. 2013;53(Suppl 1):273.
Long term culture leads to mitochondrial fusion and altered metabolism in pre-senescent fibroblasts [abstract]. Van Horn CG, Bharadwaj MS, Strober JW, Molina AJ.. Gerontologist. 2013;53(Suppl 1):276.
Role of mitofusin 2 in the renal stress response. Gall JM, Wang Z, Liesa M, Molina A, Havasi A, Schwartz JH, Shirihai O, Borkan SC, Bonegio RGB.. PLoS ONE. 2012;7(1):e31074.
A faster, high resolution, mtPA-GFP-based mitochondrial fusion assay acquiring kinetic data of multiple cells in parallel using confocal microscopy. Lovy A, Molina AJ, Cerqueira FM, Trudeau K, Shirihai OS.. J Vis Exp. 2012;65():e3991.
High glucose induces mitochondrial morphology and metabolic changes in retinal pericytes. Trudeau K, Molina AJA, Roy S.. Invest Ophthalmol Vis Sci. 2011;52(12):8657-8664.
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