Profile

Michael J. Morykwas, Ph.D.Wake Forest School of Medicine

Michael J. Morykwas, Ph.D.

Professor,

Contact Information

Academic: 336-716-5848 | Department: 336-716-4171

Email: mmorykwa@wakehealth.edu

Education & Training

  • B.S., University of Detroit-Mercy , 1981
  • M.S., University of Michigan/Ann Arbor , 1983
  • Ph.D., University of Michigan/Ann Arbor , 1988

Memberships

  • New York Academy Of Sciences
  • Am Assn Of Advancement Of Scie
  • Plastic Surgery Research Counc
  • Wound Healing Society
  • Am Burn Assn
  • Am Chemical Society
  • Am Cleft Palate-Craniofacial A
  • Am Soc Of Materials Internatio
  • Am Soc Of Plastic & Reconst.Su
Michael J. Morykwas, Ph.D.

Michael J. Morykwas, Ph.D.

Professor, Plastic & Reconstructive Surgery
Institute for Regenerative Medicine

Research Interests

biotechnology, engineering/bioengineering

Contact Information

Academic: 336-716-5848 | Department: 336-716-4171

Email: mmorykwa@wakehealth.edu

Recent Publications


Jordan JE, Mays JJ, Shelton JE, Bryant AK, Lane MR, Morykwas MJ, Argenta LC. Mechanical tissue resuscitation protects against myocardial ischemia-reperfusion injury. J Card Surg. 2014;29(1):116-123.

McGee MP, Morykwas M, Campbell D, Hoge K, Argenta L. Interstitial-matrix edema in burns: mechanistic insights from subatmospheric pressure treatment in vivo. Wound Repair Regen. 2014;22(1):96-102.

Zheng ZL, Morykwas M, Campbell D, McGee M, Hollingsworth C, Adams F, Mays J, Tatter S, Argenta L. Mechanical tissue resuscitation at the site of traumatic brain injuries reduces the volume of injury and hemorrhage in a swine model. Neurosurgery. 2014;():.

Webb LX, Argenta LC, Morykwas MJ, inventors; Wake Forest University Health Sciences, assignee. External fixation assembly and method of use. Monaco patent MC 2,094,179. 2014 Aug 1 (patent also held in Luxembourg, Italy, Ireland, France, Switzerland, Australia, Spain, and EPO). 2014;():.

McGee MP, Morykwas M, Hoge K, Campbell D, Argenta L. Interstitial-matrix' fluid-fluxes in vivo: subatmospheric pressure reverses hydration-potential in heat-denatured dermis [abstract]. Biophys J. 2013;104(2 Suppl 1):336A.

Argenta LO, Morykwas MJ, Webb LX, inventors; Wake Forest University Health Sciences, assignee. Apparatus and method for wound treatment employing periodic sub-atmospheric pressure. United States patent US 8,377,016. 2013 Feb 19. 2013;():.

Jordan JE, Pereira BD, Morykwas MJ, Lane MR, Mays JI, Colmer G, Hollingsworth C, Argenta LC. Mechanical Tissue Resuscitation (MTR) activates the RISK pathway and widens the therapeutic window for treating acute myocardial infarction [abstract]. FASEB J. 2013;27():1130.4.

Johnston ME, Zheng Z, Maldjian JA, Whitlow CT, Morykwas MJ, Jung Y. Cerebral blood flow quantification in swine using pseudo-continuous arterial spin labeling. J Magn Reson Imaging. 2013;38(5):1111-1118.

McGee MP, Morykwas M, Wang R, Jordan J, Argenta L. Interstitial matrix flow-regulation: myocardial fibroblasts respond to colloidosmotic pressure [abstract]. Circ Res. 2013;113(4 Suppl):A061.

Argenta LC, Zheng Z, Bryant A, Tatter SB, Morykwas MJ. A new method for modulating traumatic brain injury with mechanical tissue resuscitation. Neurosurgery. 2012;70(5):1281-1295.

McGee MP, Morykwas M, Shelton J, Argenta L. Collagen unfolding accelerates water influx, determining hydration in the interstitial matrix. Biophys J. 2012;103(10):2157-2166.

Wagner WD, Argenta LC, Morykwas MJ, Levi-Polyachenko N. Production of a biodegradable electrospun biomaterial with tensile strength and elasticity [abstract]. FASEB J. 2012;26(Meeting Abstracts Suppl):905.2.

McGee MP, Morykwas M, Jordan J, Argenta L. Ischemia-reperfusion injury decreases myocardial hydration potential without changing flow resistance in the interstitial matrix [abstract]. Circ Res. 2012;111(4 Suppl):235.

Morykwas MJ, Argenta LC, inventors; Wake Forest University Health Sciences, assignee. Apparatus and method for wound treatment employing periodic sub-atmospheric pressure. Israel patent IL 199,715. 2012 Nov 1. 2012;():.

Argenta LC, Carroll DL, Levi NH, Liu J, Morykwas MJ, Tatter S, Wagner WD, inventors; Wake Forest University Health Sciences and Wake Forest University, assignees. Device and method for treating central nervous system pathology. United States patent 8,267,960. 2012 Sept 8. 2012;():.

McGee MP, Morykwas MJ, Argenta LC. The local pathology of interstitial edema: surface tension increases hydration potential in heat-damaged skin. Wound Repair Regen. 2011;19(3):358-367.

Webb LX, Argenta LC, Morykwas MJ, inventors; Wake Forest University Health Sciences, assignee. External fixation assembly and method of use. United States patent US 7,931,651. 2011 Apr 26. 2011;():.

Liu J, Morykwas MJ, Argenta LC, Wagner WD. Development of a biodegradable foam for use in negative pressure wound therapy. J Biomed Mater Res B Appl Biomater. 2011;98B(2):316-322.

Webb LX, Argenta LC, Morykwas MJ, inventors; Wake Forest University Health Sciences, assignee. Directed tissue growth employing reduced pressure. Sweden patent SE 1,517,660. 2011 Aug 24; (patent also held in Germany, Netherlands, Italy, United Kingdom, Austria, Spain, Ireland, Switzerland, Monaco, France, Greece, European Patent Office, Canada). 2011;():.

Argenta LC, Morykwas MJ, Mays JJ, Thompson EA, Hammon JW, Jordan JE. Reduction of myocardial ischemia-reperfusion injury by mechanical tissue resuscitation using sub-atmospheric pressure. J Card Surg. 2010;25(2):247-252.

Wong SL, Schneider AM, Argenta LC, Morykwas MJ. Loxoscelism and negative pressure wound therapy (vacuum-assisted closure): an experimental study. Int Wound J. 2010;7(6):488-492.

McGee MP, Morykwas M, Argenta L. Fluid transport in the extracellular matrix: kinetic changes induced by metabolic inhibitors [abstract]. Biophys J. 2009;96(3 Suppl 1):626a.

McGee MP, Morykwas M, Levi-Polyachenko N, Argenta L. Swelling and pressure-volume relationships in the dermis measured by osmotic-stress technique. Am J Physiol Regul Integr Comp Physiol. 2009;296(6):R1907-1913.

Wagner WD, Liu J, Morykwas M, Argenta L. Biodegradable polymers useful in wound repair requiring negative pressure wound therapy [abstract]. FASEB J. 2009;23(Meeting Abstracts):469.7.

Liu J, Argenta L, Morykwas M, Carroll D, Wagner W. Production of a nanocomposite for tissue repair application requiring viscoelasticity [abstract]. FASEB J. 2009;23(Meeting Abstracts):468.2.

Jordan JE, Morykwas MJ, Mays JJ, Thompson EA, Argenta LC. Mechanical tissue resuscitation (MTR) reduces myocardial reperfusion injury [abstract]. FASEB J. 2009;23(Meeting Abstracts):793.1.

Wong SL, Defranzo AJ, Morykwas MJ, Argenta LC. Loxoscelism and negative pressure wound therapy (vacuum-assisted closure): a clinical case series. Am Surg. 2009;75(11):1128-1131.

Argenta L, Morykwas M, Zheng Z-l, Wagner W, Tatter S. Controlled negative pressure reduces brain edema and modulates brain metabolites in a brain injury model [abstract]. J Neurotrauma. 2008;25(7):930.

McGee MP, Morykwas M, Argenta L. Coagulation responses during tissue injury and repair: water potential as an independent variable across biological scales [abstract]. In: Abstract Booklet of the 18th Annual Growth Factor and Signal Transduction Symposium: Systems Biology: Integrative, Comparative, and Multi-Scale Modeling; 2008 Sept 18-21; Ames (IA). 2008;():27.

Dedmond BT, Kortesis B, Punger K, Simpson J, Argenta J, Kulp B, Morykwas M, Webb LX. The use of negative-pressure wound therapy (NPWT) in the temporary treatment of soft-tissue injuries associated with high-energy open tibial shaft fractures. J Orthop Trauma. 2007;21(1):11-17.

Sanger C, Argenta A, Morykwas M, Glazier SS, Argenta LC, David LR. Dynamic spring mediated cranioplasty in an experimental model with resorbable foot plates. J Craniofac Surg. 2007;18(1):54-59.

Argenta L, Morykwas M, inventors; Wake Forest University Health Sciences, assignee. Wound treatment employing reduced pressure. United States patent US 7,198,046. 2007 Apr 3. 2007;():.

Argenta L, Morykwas M, inventors; Wake Forest University Health Sciences, assignee. Wound treatment employing reduced pressure. United States patent US 7,216,651. 2007 May 15. 2007;():.

Morykwas MJ, Simpson J, Punger K, Argenta A, Kremers L, Argenta J. Vacuum-assisted closure: state of basic research and physiologic foundation. Plast Reconstr Surg. 2006;117(7 Suppl):121S-126S.

Dedmond BT, Kortesis B, Punger K, Simpson J, Argenta J, Kulp B, Morykwas M, Webb LX. Subatmospheric pressure dressings in the temporary treatment of soft tissue injuries associated with type III open tibial shaft fractures in children. J Pediatr Orthop. 2006;26(6):728-732.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

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