Profile

Michael Thomas Munley, Ph.D.Wake Forest School of Medicine

Michael Thomas Munley, Ph.D.

Professor,

Contact Information

Academic: 336-713-6538 | Department: 336-713-3600

Email: mmunley@wakehealth.edu

Education & Training

  • B.S.E., Duke University, 1988
  • Ph.D., Duke University, 1993

Memberships

  • N Am Hyperthermia Group
  • Phi Eta Sigma
  • Sigma Xi - Research Society
  • Am Assn Of Physicists In Med
  • Am Board Of Radiology
  • Am Coll Of Medical Physics
  • Am Soc Of Ther Rad & Oncology
Michael Thomas Munley, Ph.D.

Michael Thomas Munley, Ph.D.

Professor, Radiation Oncology
Biomedical Engineering

Research Interests

Radiosurgery; Lung Neoplasms; Neoplasms, Radiation-Induced; Magnetic Resonance Imaging; Brain Neoplasms
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Contact Information

Academic: 336-713-6538 | Department: 336-713-3600

Email: mmunley@wakehealth.edu

Recent Publications

Early dose-dependent cortical thinning of the femoral neck in anal cancer patients treated with pelvic radiation therapy. Okoukoni C, Randolph DM, McTyre ER, Kwok A, Weaver AA, Blackstock AW, Munley MT, Willey JS.. Bone. 2017;94():84-89.

Image guided radiation therapy may result in improved local control in locally advanced lung cancer patients. Kilburn JM, Soike MH, Lucas JT, Ayala-Peacock D, Blackstock W, Isom S, Kearns WT, Hinson WH, Miller AA, Petty WJ, Munley MT, Urbanic JJ.. Pract Radiat Oncol. 2016;6(3):e73-e80.

Emerging indications for fractionated gamma knife radiosurgery. McTyre E, Helis CA, Farris M, Wilkins L, Sloan D, Hinson WH, Bourland JD, Dezarn WA, Munley MT, Watabe K, Xing F, Laxton AW, Tatter SB, Chan MD.. Neurosurgery. 2016;():.

A model for preemptive maintenance of medical linear accelerators-predictive maintenance. Able CM, Baydush AH, Nguyen C, Gersh J, Ndlovu A, Rebo I, Booth J, Perez M, Sintay B, Munley MT.. Radiat Oncol. 2016;11(1):36.

Is a clinical target volume (CTV) necessary in the treatment of lung cancer in the modern era combining 4-D imaging and image-guided radiotherapy (IGRT)?. Kilburn JM, Lucas JT, Soike MH, Ayala-Peacock DN, Blackstock AW, Hinson WH, Munley MT, Petty WJ, Urbanic JJ.. Cureus. 2016;8(1):e466.

A cortical thickness and radiation dose mapping approach identifies early thinning of ribs after stereotactic body radiation therapy. Okoukoni C, Lynch SK, McTyre ER, Randolph DM, Weaver AA, Blackstock AW, Lally BE, Munley MT, Willey JS.. Radiother Oncol. 2016;119(3):449-453.

Repeat stereotactic radiosurgery as salvage therapy for locally recurrent brain metastases previously treated with radiosurgery. McKay WH, McTyre ER, Okoukoni C, Alphonse-Sullivan NK, Ruiz J, Munley MT, Qasem S, Lo HW, Xing F, Laxton AW, Tatter SB, Watabe K, Chan MD.. J Neurosurg. 2016;():.

Spaceflight-relevant challenges of radiation and/or reduced weight bearing cause arthritic responses in knee articular cartilage. Willey JS, Kwok AT, Moore JE, Payne V, Lindburg CA, Balk SA, Olson J, Black PJ, Walb MC, Yammani RR, Munley MT.. Radiat Res. 2016;186(4):333-344.

A reproducible radiation delivery method for unanesthetized rodents during periods of hind limb unloading. Walb MC, Black PJ, Payne VS, Munley MT, Willey JS.. Life Sci Space Res (Amst). 2015;6():10-14.

Factors that determine local control with gamma knife radiosurgery: the role of primary histology. Black PJ, Page BR, Lucas JT Jr, Hughes RT, Laxton AW, Tatter SB, Munley MT, Chan MD.. J Radiosurg SBRT. 2015;3(4):281-286.

Thoracic SBRT induces early deterioration of cortical bone in ribs [abstract]. Okoukoni C, Lynch S, Weaver A, Blackstock AW, Lally BE, Munley MT, Willey J.. Int J Radiat Oncol Biol Phys. 2015;93(3 Suppl):S83.

Acute cortical bone thinning in the femoral head after pelvic radiation therapy [abstract]. Randolph DM II, Okoukoni C, Isom S, Munley MT, Lally BE, Blackstock AW, Willey J.. Int J Radiat Oncol Biol Phys. 2015;93(3 Suppl):E491-E492.

Local control and toxicity outcomes in brainstem metastases treated with single fraction radiosurgery: is there a volume threshold for toxicity?. Kilburn JM, Ellis TL [deceased], Lovato JF, Urbanic JJ, Bourland JD, Munley MT, Deguzman AF, McMullen KP, Shaw EG, Tatter SB, Chan MD.. J Neurooncol. 2014;117(1):167-174.

Single-institution retrospective series of gamma knife radiosurgery in the treatment of multiple sclerosis-related trigeminal neuralgia: factors that predict efficacy. Weller M, Marshall K, Lovato JF, Bourland JD, deGuzman AF, Munley MT, Shaw EG, Tatter SB, Chan MD.. Stereotact Funct Neurosurg. 2014;92(1):53-58.

Management of mediastinal relapse after treatment with stereotactic body radiotherapy or accelerated hypofractionated radiotherapy for stage I/II non-small-cell lung cancer. Kilburn JM, Lester SC, Lucas JT Jr, Soike MH, Blackstock AW, Kearns WT, Hinson WH, Miller AA, Petty WJ, Munley MT, Urbanic JJ.. J Thorac Oncol. 2014;9(4):572-576.

Thoracic re-irradiation using stereotactic body radiotherapy (SBRT) techniques as first or second course of treatment. Kilburn JM, Kuremsky JG, Blackstock AW, Munley MT, Kearns WT, Hinson WH, Lovato JF, Miller AA, Petty WJ, Urbanic JJ.. Radiother Oncol. 2014;110(3):505-510.

A model for pre-emptive maintenance of medical linear accelerators: predictive maintenance [abstract]. Able CM, Baydush AH, Nguyen C, Gersh J, Ndlovu A, Booth J, Perez M, Sintay BJ, Munley MT.. Int J Radiat Oncol Biol Phys. 2014;90(Suppl 1):S738.

Which lung tumors shrink during fractionated radiation and how does this influence outcome?: Appropriately selecting tumor and treatment characteristics for adaptive radiation therapy protocols [abstract]. Kilburn JM, Lucas JT, Soike MH, Ayala-Peacock D, Kuremsy JG, Blackstock A, Hinson WH, Miller AA, Petty WJ, Munley MT, Urbanic JJ.. Int J Radiat Oncol Biol Phys. 2014;90(Suppl 1):S641-S642.

An evaluation of toxicity using accumulated total dose based on EQD2 for thoracic reirradiation incorporating at least 1 course of SBRT [abstract]. Lester SC, Kilburn JM, Lucas JT, Soike MH, Blackstock AW, Hinson WH, Miller AA, Petty WJ, Munley MT, Urbanic JJ.. Int J Radiat Oncol Biol Phys. 2014;90(Suppl 1):S640-S641.

Impact of breathing 100% oxygen on radiation-induced cognitive impairment. Wheeler KT, Payne V, D'Agostino RB Jr, Walb MC, Munley MT, Metheny-Barlow LJ, Robbins ME [deceased].. Radiat Res. 2014;182(5):580-585.

Total-body irradiation produces late degenerative joint damage in rats. Hutchinson ID, Olson J, Lindburg CA, Payne V, Collins B, Smith TL, Munley MT, Wheeler KT, Willey JS.. Int J Radiat Biol. 2014;90(9):821-830.

The role of alveolar epithelium in radiation-induced lung injury. Almeida C, Nagarajan D, Tian J, Leal SW, Wheeler K, Munley M, Blackstock W, Zhao W.. PLoS One. 2013;8(1):e53628.

Chemoprevention by N-acetylcysteine of low-dose CT-induced murine lung tumorigenesis. Miller MS, Moore JE, Walb MC, Kock ND, Attia A, Isom S, McBride JE, Munley MT.. Carcinogenesis. 2013;34(2):319-324.

An introduction to molecular imaging in radiation oncology:aA report by the AAPM Working Group on Molecular Imaging in Radiation Oncology (WGMIR). Munley MT, Kagadis GC, McGee KP, Kirov AS, Jang S, Mutic S, Jeraj R, Xing L, Bourland JD.. Med Phys. 2013;40(10):101501.

Stereotactic body radiation therapy (SBRT) and image guided accelerated hypofractionated radiation therapy (IGAHRT) for the treatment of oligometastatic cancers [abstract]. Ayala-Peacock DN, Blackstock AW, Kearns WT, Hinson WH, Munley MT, Miller AA, Petty WJ, Urbanic JJ.. Int J Radiat Oncol Biol Phys. 2013;87(2 Suppl):S567-S568.

Multiple courses of thoracic radiation therapy (XRT) using stereotactic body radiation therapy (SBRT) as the first or second course of treatment for tumors outside the original high-dose region [abstract]. Kilburn JM, Lester SC, Lucas JT, Blackstock AW, Kearns WT, Hinson WH, Munley MT, Miller AA, Petty WJ, Urbanic JJ.. Int J Radiat Oncol Biol Phys. 2013;87(2 Suppl):S36.

Salvage radiation for mediastinal relapse after treatment with accelerated hypofractionated radiation therapy (AHRT) or stereotactic body radiation therapy (SBRT) for stage I/II NSCLC [abstract]. Lester SC, Kilburn JM, Lucas JT, Munley MT, Blackstock AW, Kearns WT, Hinson WH, Miller AA, Petty WJ, Urbanic JJ.. Int J Radiat Oncol Biol Phys. 2013;87(2 Suppl):S543-S544.

Predictive variables for the successful treatment of trigeminal neuralgia with gamma knife radiosurgery. Marshall K, Chan MD, McCoy TP, Aubuchon AC, Bourland JD, McMullen KP, deGuzman AF, Munley MT, Shaw EG, Tatter SB, Ellis TL.. Neurosurgery. 2012;70(3):566-573.

Gamma knife stereotactic radiosurgery as salvage therapy after failure of whole-brain radiotherapy in patients with small-cell lung cancer. Harris S, Chan MD, Lovato JF, Ellis TL, Tatter SB, Bourland JD, Munley MT, deGuzman AF, Shaw EG, Urbanic JJ, McMullen KP.. Int J Radiat Oncol Biol Phys. 2012;83(1):e53-e59.

Patterns of failure after treatment of atypical meningioma with gamma knife radiosurgery. Attia A, Chan MD, Mott RT, Russell GB, Seif D, Bourland JD, Deguzman AF, Ellis TL, McMullen KP, Munley MT, Tatter SB, Shaw EG.. J Neurooncol. 2012;108(1):179-185.

A technique for murine irradiation in a controlled gas environment. Walb MC, Moore JE, Attia A, Wheeler KT, Miller MS, Munley MT.. Biomed Sci Instrum. 2012;48():470-477.

A gated-7T MRI technique for tracking lung tumor development and progression in mice after exposure to low doses of ionizing radiation. Olson JD, Walb MC, Moore JE, Attia A, Sawyer HL, McBride JE, Wheeler KT, Miller MS, Munley MT.. Radiat Res. 2012;178(4):321-327.

Retrospective analysis of imaging techniques for treatment planning and monitoring of obliteration for gamma knife treatment of cerebral arteriovenous malformation. Amponsah K, Ellis TL [deceased], Chan MD, Lovato JF, Bourland JD, deGuzman AF, Ekstrand KE, Munley MT, McMullen KP, Shaw EG, Tatter SB.. Neurosurgery. 2012;71(4):893-900.

Gamma knife radiosurgery in the treatment of tumor-related facial pain. Squire SE, Chan MD, Furr RM, Lowell DA, Tatter SB, Ellis TL [deceased], Bourland JD, Deguzman AF, Munley MT, Ekstrand KE, Shaw EG, McMullen KP.. Stereotact Funct Neurosurg. 2012;90(3):145-150.

Clinical outcomes of brain metastases treated with Gamma Knife radiosurgery with 3.0T versus 1.5T MRI-based treatment planning: have we finally optimised detection of occult brain metastases?. Loganathan AG, Chan MD, Alphonse N, Peiffer AM, Johnson AJ, McMullen KP, Urbanic JJ, Saconn PA, Bourland JD, Munley MT, Shaw EG, Tatter SB, Ellis TL [deceased].. J Med Imaging Radiat Oncol. 2012;56(5):554-560.

Cavity-directed radiosurgery as adjuvant therapy after resection of a brain metastasis. Jensen CA, Chan MD, McCoy TP, Bourland JD, deGuzman AF, Ellis TL, Ekstrand KE, McMullen KP, Munley MT, Shaw EG, Urbanic JJ, Tatter SB.. J Neurosurg. 2011;114(6):1585-1591.

Repeat gamma knife radiosurgery for trigeminal neuralgia. Aubuchon AC, Chan MD, Lovato JF, Balamucki CJ, Ellis TL, Tatter SB, McMullen KP, Munley MT, Deguzman AF, Ekstrand KE, Bourland JD, Shaw EG.. Int J Radiat Oncol Biol Phys. 2011;81(4):1059-1065.

Toxicity of gamma knife radiosurgery in the treatment of intracranial tumors in patients with collagen vascular diseases or multiple sclerosis. Lowell D, Tatter SB, Bourland JD, DeGuzman AF, Ekstrand KE, Ellis TL, Lovato JF, McMullen KP, Munley MT, Shaw EG, Urbanic JJ, Chan MD.. Int J Radiat Oncol Biol Phys. 2011;81(4):e519-e524.

Outcomes for gamma knife radiosurgery for brainstem metastases [abstract]. Kilburn JM, Ellis TL, Urbanic JJ, Bourland JD, Munley MT, deGuzman AF, McMullen KP, Shaw EG, Tatter SB, Chan MD.. Int J Radiat Oncol Biol Phys. 2011;81(2 Suppl):S302.

Clinical outcomes of brain metastases treated with gamma knife radiosurgery with 3.0 T vs. 1.5 T MRI-based treatment planning [abstract]. Loganathan AG, Chan MD, Alphonse N, Peiffer AM, Johnson A, McMullen KP, Urbanic JJ, Saconn PA, Bourland JD, Munley MT, Shaw EG, Tatter SB, Ellis TL.. Neuro Oncol. 2011;13(Suppl 3):129.

Cancer-prone mice expressing the Ki-rasG12C gene show increased lung carcinogenesis after CT screening exposures. Munley MT, Moore JE, Walb MC, Isom SP, Olson JD, Zora JG, Kock ND, Wheeler KT, Miller MS.. Radiat Res. 2011;176(6):842-848.

Initial investigation using statistical process control for quality control of accelerator beam steering. Able CM, Hampton CJ, Baydush AH, Munley MT.. Radiat Oncol. 2011;6():180.

Low-dose CT irradiation increases lung tumorigenesis in a Ki-ras driven mouse model: results from a pilot study [abstract]. Miller MS, Moore JE, Olson J, Kock ND, Zora JG, Wheeler K, Munley MT.. J Thorac Oncol. 2010;5(6 Suppl 3):S230.

Use of 3.0-T MRI for stereotactic radiosurgery planning for treatment of brain metastases: a single-institution retrospective review. Saconn PA, Shaw EG, Chan MD, Squire SE, Johnson AJ, McMullen KP, Tatter SB, Ellis TL, Lovato J, Bourland JD, Ekstrand KE, DeGuzman AF, Munley MT.. Int J Radiat Oncol Biol Phys. 2010;78(4):1142-1146.

Analysis of toxicity in patients with collagen vascular diseases or multiple sclerosis treated with gamma knife radiosurgery for intracranial tumors [abstract]. Lowell DA, Shaw EG, Bourland JD, de Guzman AF, Ekstrand KE, Ellis TL, McMullen KP, Munley MT, Tatter SB, Chan MD.. Int J Radiat Oncol Biol Phys. 2010;78(3 Suppl):S269-S270.

Improved volumetric imaging in tomosynthesis using combined multiaxial sweeps. Gersh JA, Wiant DB, Best RC, Bennett MC, Munley MT, King JD, McKee MM, Baydush AH.. J Appl Clin Med Phys. 2010;11(4):181-195.

Increased lung tumorigenesis following low dose CT radiation [abstract]. Munley M, Moore J, Olson J, Isom S, Walb M, Zora JG, Kock N, Wheeler K, Miller M.. In: Abstracts of the 56th Annual Meeting of the Radiation Research Society; 2010 Sept 25-29; Maui (HI). 2010;():137.

Relationship between radiosurgery conformity indices and acoustic neuroma tumor volume. Lawrence MV, Rossi P, Powell D, Ekstrand KE, deGuzman AF, Munley MT, Ellis TL, Tatter SB, Stieber VW, McMullen KP, Shaw EG, Bourland JD. In: McDermott MW, ed. Radiosurgery. New York: Karger;2010: 95-99.

Clinical experience with radiation therapy in the management of neurofibromatosis-associated central nervous system tumors. Wentworth S, Pinn M, Bourland JD, DeGuzman AF, Ekstrand K, Ellis TL, Glazier SS, McMullen KP, Munley M, Stieber VW, Tatter SB, Shaw EG.. Int J Radiat Oncol Biol Phys. 2009;73(1):208-213.

Dorsal root entry zone dose predicts efficacy and toxicity for patients receiving a second radiosurgical treatment for recurrent trigeminal neuralgia [abstract]. Aubuchon AC, Chan M, Lovano J, McMullen K, Ellis T, Tatter S, Bourland J, Deguzman A, Munley M, Shaw E.. Int J Radiat Oncol Biol Phys. 2009;75(3 Suppl 1):S240.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Professor, Radiation Oncology

Michael Thomas Munley, Ph.D.

Michael Thomas Munley, Ph.D.

Professor, Radiation Oncology
Biomedical Engineering

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