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Research

Mariana Murea, M.D.

Assistant Professor, Nephrology

Clinical Specialties

End-stage Renal Disease, Kidney Disease (Chronic), Acute Kidney Injury

Contact Information

New Patient Appointments: 336-716-WAKE
Returning Patient Appointments: 336-716-2406
Department: 336-716-4650

Education & Training

M.D., Carol Davila University of Medicine & Pharmacy , 1998
Internship, "Ion Cantacuzino" Hospital, 2000
Residency, Internal Medicine, University Hospital of Bucharest, 2001
Residency, Danbury Hospital - Affil of Yale Univ Med School and New York Medical College, 2004
Fellowship, Nephrology, Albert Einstein College of Medicine, 2009

Board Certifications

American Board of Internal Medicine, Internal Medicine
American Board of Internal Medicine, Internal Medicine, Nephrology

Memberships

Nat'L Kidney Foundation
Am Soc Of Nephrology

Additional Languages

Romanian

NPI Number

1396792321

Mariana Murea, M.D.

Assistant Professor, Nephrology

Contact Information

Academic: 336-716-2406 | Department: 336-716-4650

Recent Publications

Freedman BI, Murea M. Target organ damage in African American hypertension: role of APOL1. Curr Hypertens Rep. 2012;14(1):21-28.

Murea M, Ma L, Freedman BI. Genetic and environmental factors associated with type 2 diabetes and diabetic vascular complications. Rev Diabet Stud. 2012;9(1):6-22.

Murea M. Advanced kidney failure and hyperuricemia. Adv Chronic Kidney Dis. 2012;19(6):419-424.

Murea M, Moran T, Russell GB, Shihabi ZK, Byers JR, Andries L, Bleyer AJ, Freedman BI. Glycated albumin, not hemoglobin A1c, predicts cardiovascular hospitalization and length of stay in diabetic patients on dialysis. Am J Nephrol. 2012;36(5):488-496.

Freedman BI, Langefeld CD, Turner J, Nunez M, High KP, Spainhour M, Hicks PJ, Bowden DW, Reeves-Daniel AM, Murea M, Rocco MV, Divers J. Association of APOL1 variants with mild kidney disease in the first-degree relatives of African American patients with non-diabetic end-stage renal disease. Kidney Int. 2012;82(7):805-811.

Murea M, Register TC, Divers J, Bowden DW, Carr JJ, Hightower CR, Xu J, Smith SC, Hruska KA, Langefeld CD, Freedman BI. Relationships between serum MCP-1 and subclinical kidney disease: African American-Diabetes Heart Study. BMC Nephrol. 2012;13(1):148.

Murea M, Russell GB, Bleyer AJ, Freedman BI. Glycated albumin (GA), not hemoglobin A1c (HbA1c), predicts cardiovascular hospitalizations and length of stay (LOS) in dialysis patients with diabetes [abstract]. J Am Soc Nephrol. 2012;23():751A.

Chen Z, Freedman BI, Graham WD, Ross NA, Pollak MR, Ross MD, Murea M, Ma L, Antinozzi PA. Dose-dependent expression of ApoL1 protein sensitizes cell death pathways [abstract]. J Am Soc Nephrol. 2012;23():136A.

Freedman BI, Murea M, Rocco MV, Ma L, Bowden DW, Ornelles DA, Kleiboeker S, Langefeld CD, Turner J, Divers J. JC polyoma virus interacts with apolipoprotein L1 genetic risk in African Americans with non-diabetic nephropathy [abstract]. J Am Soc Nephrol. 2012;23():178A.

Freedman BI, Bowden DW, Murea M. Protein kinase C-beta gene variants and type 2 diabetes-associated kidney failure: what can we learn from gene association studies in diabetic nephropathy? [commentary]. Am J Kidney Dis. 2011;57(2):194-197.

Reeves-Daniel AM, DePalma JA, Bleyer AJ, Rocco MV, Murea M, Adams PL, Langefeld CD, Bowden DW, Hicks PJ, Stratta RJ, Lin J-J, Kiger DF, Gautreaux MD, Divers J, Freedman BI. The APOL1 gene and allograft survival after kidney transplantation. Am J Transplant. 2011;11(5):1025-1030.

Murea M, Lu L, Ma L, Hicks PJ, Divers J, McDonough CW, Langefeld CD, Bowden DW, Freedman BI. Genome-wide association scan for survival on dialysis in African-Americans with type 2 diabetes. Am J Nephrol. 2011;33(6):502-509.

Ma L, Mondal AK, Murea M, Sharma NK, Langberg KA, Das SK, Antinozzi PA, Parks JS, Elbein SC [deceased], Freedman BI, et al. The effect of ACACB cis-variants on gene expression and metabolic traits. PLoS ONE. 2011;6(8):e23860.

Murea M, Register TC, Divers J, Bowden DW, Carr JJ, Hightower RC, Smith SC, Hruska KA, Langefeld CD, Freedman BI. Relationships between serum MCP-1 and subclinical kidney disease: African American-Diabetes Heart Study [abstract]. J Am Soc Nephrol. 2011;22(Abstract Suppl):715A.

Freedman BI, Langefeld CD, Murea M, Ma L, Otvos JD, Turner J, Antinozzi PA, Rocco MV, Parks JS. Apolipoprotein L1 (APOL1) nephropathy risk variants associate with HDL subfraction concentration in African Americans [abstract]. J Am Soc Nephrol. 2011;22(Abstract Suppl):178A.

Bleyer AJ, Murea M. Antimicrobial catheter locks: searching for the ideal solution [editorial]. J Am Soc Nephrol. 2011;22(10):1781-1782.

Freedman BI, Langefeld CD, Murea M, Ma L, Otvos JD, Turner J, Antinozzi PA, Divers J, Hicks PJ, Bowden DW, Rocco MV, Parks JS. Apolipoprotein L1 nephropathy risk variants associate with HDL subfraction concentration in African Americans. Nephrol Dial Transplant. 2011;26(11):3805-3810.

Murea M, Freedman BI. Essential hypertension and risk of nephropathy: a reappraisal. Curr Opin Nephrol Hypertens. 2010;19(3):235-241.

Freedman BI, Edberg JC, Comeau ME, Murea M, Bowden DW, Divers J, Alarcon GS, Brown EE, McGwin G Jr, Langefeld CD, et al. The non-muscle myosin heavy chain 9 gene (MYH9) is not associated with lupus nephritis in African Americans. Am J Nephrol. 2010;32(1):66-72.

Freedman BI, Murea M. Potential effects of MYH9-associated nephropathy on dialysis and kidney transplant outcomes. Semin Dial. 2010;23(3):244-247.

Deshpande P, Chen J, Gofran A, Murea M, Golestaneh L. Meropenem removal in critically ill patients undergoing sustained low-efficiency dialysis (SLED). Nephrol Dial Transplant. 2010;25(8):2632-2636.

Murea M, Freedman BI, Parks JS, Antinozzi PA, Elbein SC [deceased], Ma L. Lipotoxicity in diabetic nephropathy: the potential role of fatty acid oxidation. Clin J Am Soc Nephrol. 2010;5(12):2373-2379.

Murea M, Park J-K, Sharma S, Kato H, Gruenwald A, Niranjan T, Si H, Thomas DB, Pullman JM, Melamed ML, et al. Expression of Notch pathway proteins correlates with albuminuria, glomerulosclerosis, and renal function. Kidney Int. 2010;78(5):514-522.

Antinozzi PA, Barnes BC, Deegan D, Ma L, Freedman BI, Murea M. Digital deconstruction of heterogeneous renal cell preparations with high-content imaging and cell specific biomarkers [abstract]. J Am Soc Nephrol. 2010;21(Suppl):409A.

Murea M, Lu L, Hicks PJ, Bowden DW, Divers J, Langefeld CD, Freedman BI. Genetic variants identified by GWAS suggest intracellular calcium, vascular remodeling, and cardiac repolarization pathways impact dialytic survival in African Americans with diabetes [abstract]. J Am Soc Nephrol. 2010;21(Suppl):730A.