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Michael A. Nader, Ph.D.Wake Forest School of Medicine

Michael A. Nader, Ph.D.


Contact Information

Academic: 336-713-7172 | Department: 336-713-1520


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Education & Training

  • B.S., Wayne State University, 1982
  • Ph.D., University of Minnesota, 1985
  • Fellowship, Uniformed Services University, 1987


  • Am Coll of Neuropsychopharm
  • Am Soc for Pharm & Exper Ther
  • Behavioral Pharmacology Societ
  • Coll on Probs of Drug Dependen
Michael A. Nader, Ph.D.

Michael A. Nader, Ph.D.

Professor, Physiology & Pharmacology
Comprehensive Cancer Center

Research Interests

Cocaine; Cocaine-Related Disorders; Reinforcement (Psychology); Dopamine Uptake Inhibitors; Self Administration
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Contact Information

Academic: 336-713-7172 | Department: 336-713-1520


Media Medical Expert »

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Recent Publications

Chronic delta9-THC in rhesus monkeys: effects on cognitive performance and dopamine D2/D3 receptor availability. John WS, Martin TJ, Solingapuram Sai KK, Nader SH, Gage HD, Mintz A, Nader MA.. J Pharmacol Exp Ther. 2018;364(2):300-310.

Labyrinthitis ossificans in a cynomolgus macaque (Macaca fascicularis). Balamayooran G, Atkins HM, Whitlow CT, Aycock ST, Nader MA, Cline JM, Caudell DL.. Comp Med. 2018;():.

Social status in monkeys: effects of social confrontation on brain function and cocaine self-administration. Gould RW, Czoty PW, Porrino LJ, Nader MA.. Neuropsychopharmacology. 2017;42(5):1093-1102.

Behavioral determinants of cannabinoid self-administration in Old World monkeys. John WS, Martin TJ, Nader MA.. Neuropsychopharmacology. 2017;42(7):1522-1530.

Effects of social reorganization on dopamine D2/D3 receptor availability and cocaine self-administration in male cynomolgus monkeys. Czoty PW, Gould RW, Gage HD, Nader MA.. Psychopharmacology (Berl). 2017;234(18):2673-2682.

Effects of alpha-2 norepinephrine receptor agonists on cocaine self-administration in monhuman primate models [abstract]. Czoty PW, Coller M, Odom J, Epperly P, John WS, Nader SH, Nader MA.. FASEB J. 2017;31(Suppl 1):987.6.

Methamphetamine self-administration history may increase the reinforcing effects of cannabinoid receptor agonists in rhesus monkeys [abstract]. Minkiewicz M, John WS, Nader M.. FASEB J. 2017;31(Suppl 1):811.4.

Effects of daily oral phendimetrazine on cocaine-food choice in rhesus monkeys [abstract]. Stowe TA, Nader M, Czoty P.. FASEB J. 2017;31(Suppl 1):987.1.

Yawning elicited by intravenous ethanol in rhesus monkeys with experience self-administering cocaine and ethanol: involvement of dopamine D3 receptors. Czoty PW, John WS, Newman AH, Nader MA.. Alcohol. 2017;69():1-5.

Functional consequences of cocaine expectation: findings in a non-human primate model of cocaine self-administration. Porrino LJ, Beveridge TJ, Smith HR, Nader MA.. Addict Biol. 2016;21(3):519-529.

Effects of abstinence from chronic cocaine self-administration on nonhuman primate dorsal and ventral noradrenergic bundle terminal field structures. Smith HR, Beveridge TJ, Nader MA, Porrino LJ.. Brain Struct Funct. 2016;221(5):2703-2715.

Evaluation of the reinforcing effect of quetiapine, alone and in combination with cocaine, in rhesus monkeys. Brutcher RE, Nader SH, Nader MA.. J Pharmacol Exp Ther. 2016;356(2):244-250.

Preclinical laboratory assessments of predictors of social rank in female cynomolgus monkeys. Kromrey SA, Czoty PW, Nader SH, Register TC, Nader MA.. Am J Primatol. 2016;78(4):402-417.

Multi-atlas library for eliminating normalization failures in non-human primates. Maldjian JA, Shively CA, Nader MA, Friedman DP, Whitlow CT.. Neuroinformatics. 2016;14(2):183-190.

Animal models for addiction medicine: from vulnerable phenotypes to addicted individuals. Nader MA.. Prog Brain Res. 2016;224():3-24.

Attenuation of cocaine self-administration by chronic oral phendimetrazine in rhesus monkeys. Czoty PW, Blough BE, Fennell TR, Snyder RW, Nader MA.. Neuroscience. 2016;324():367-376.

Neural correlates of exposure to cocaine cues in rhesus monkeys: modulation by the dopamine transporter. Porrino LJ, Miller MD, Smith HR, Nader SH, Nader MA.. Biol Psychiatry. 2016;80(9):702-710.

Dietary modification of physiological responses to chronic psychosocial stress: implications for the obesity epidemic. Shively CA, Fimmel A, Jones S, Nader M. In: Shively CA, Wilson ME, eds. Social inequalities in health in nonhuman primates: the biology of the gradient. Switzerland: Springer;2016: 159-178.

Time to connect: bringing social context into addiction neuroscience. Heilig M, Epstein DH, Nader MA, Shaham Y.. Nat Rev Neurosci. 2016;17(9):592-599.

A novel orvinol analog, BU08028, as a safe opioid analgesic without abuse liability in primates. Ding H, Czoty PW, Kiguchi N, Cami-Kobeci G, Sukhtankar DD, Nader MA, Husbands SM, Ko MC.. Proc Natl Acad Sci U S A. 2016;113(37):E5511-5518.

Effects of ethanol on cocaine self-administration in monkeys responding under a second-order schedule of reinforcement. John WS, Nader MA.. Drug Alcohol Depend. 2016;170():112-119.

Effects of quetiapine treatment on cocaine self-administration and behavioral indices of sleep in adult rhesus monkeys. Brutcher RE, Nader MA.. Psychopharmacology (Berl). 2015;232(2):411-420.

Effects of buspirone and the dopamine D3 receptor compound PG619 on cocaine and methamphetamine self-administration in rhesus monkeys using a food-drug choice paradigm. John WS, Banala AK, Newman AH, Nader MA.. Psychopharmacology (Berl). 2015;232(7):1279-1289.

Effects of oral and intravenous administration of buspirone on food-cocaine choice in socially housed male cynomolgus monkeys. Czoty PW, Nader MA.. Neuropsychopharmacology. 2015;40(5):1072-1083.

Differential effects of the dopamine D3 receptor antagonist PG01037 on cocaine and methamphetamine self-administration in rhesus monkeys. John WS, Newman AH, Nader MA.. Neuropharmacology. 2015;92():34-43.

Effects of prior cocaine self-administration on cognitive performance in female cynomolgus monkeys. Kromrey SA, Gould RW, Nader MA, Czoty PW.. Psychopharmacology (Berl). 2015;232(11):2007-2016.

Identifying medication targets for psychostimulant addiction: unraveling the dopamine D3 receptor hypothesis. Keck TM, John WS, Czoty PW, Nader MA, Newman AH.. J Med Chem. 2015;58(14):5361-5380.

Relationship between estradiol and progesterone concentrations and cognitive performance in normally cycling female cynomolgus monkeys. Kromrey SA, Czoty PW, Nader MA.. Horm Behav. 2015;72():12-19.

Improved automated radiosynthesis of [(11)C]PBR28. Sai KKS, Gage D, Nader M, Mach RH, Mintz A.. Sci Pharm. 2015;83(3):413-427.

Ethanol/cocaine interactions: abuse-related and unconditioned behaviors in rhesus monkeys [abstract]. Czoty P, John W, Nader M, Newman A, Epperly P.. Neuropsychopharmacology. 2015;40(Suppl 1):S441-S442.

Environmental modulation of drug taking: nonhuman primate models of cocaine abuse and PET neuroimaging. Nader MA, Banks ML.. Neuropharmacology. 2014;76(Pt B):510-517.

Effects of repeated treatment with the dopamine D2/D3 receptor partial agonist aripiprazole on striatal D2/D3 receptor availability in monkeys. Czoty PW, Gage HD, Garg PK, Garg S, Nader MA.. Psychopharmacology (Berl). 2014;231(3):613-619.

Regionally-specific alterations in myelin proteins in nonhuman primate white matter following prolonged cocaine self-administration. Smith HR, Beveridge TJ, Nader MA, Porrino LJ.. Drug Alcohol Depend. 2014;137():143-147.

Further characterization of quinpirole-elicited yawning as a model of dopamine D3 receptor activation in male and female monkeys. Martelle SE, Nader SH, Czoty PW, John WS, Duke AN, Garg PK, Garg S, Newman AH, Nader MA.. J Pharmacol Exp Ther. 2014;350(2):205-211.

Functional consequences of cocaine re-exposure after discontinuation of cocaine availability. Beveridge TJ, Smith HR, Nader SH, Nader MA, Porrino LJ.. Neuropharmacology. 2014;85():528-537.

PET studies in nonhuman primate models of cocaine abuse: translational research related to vulnerability and neuroadaptations. Gould RW, Duke AN, Nader MA.. Neuropharmacology. 2014;84():138-151.

Why primate models matter. Phillips KA, Bales KL, Capitanio JP, Conley A, Czoty PW, 't Hart BA, Hopkins WD, Hu SL, Miller LA, Nader MA, Nathanielsz PW, Rogers J, Shively CA, Voytko ML.. Am J Primatol. 2014;76(9):801-827.

William L. Woolverton: a case history in unraveling the behavioral pharmacology of stimulants. Nader MA, Balster RL, Henningfield JE.. Neuropharmacology. 2014;87():4-8.

Cognitive performance and homecage activity in female cynomolgus monkeys: relationship to social rank and cocaine reinforcement [abstract]. Kromrey S, Czoty P, Rowe M, Nader M.. FASEB J. 2014;28(1 Suppl):848.1.

Effects of selective dopamine D3 receptor compounds in nonhuman primate models of cocaine and methamphetamine abuse [abstract]. John W, Green H, Newman A, Nader M.. FASEB J. 2014;28(1 Suppl):661.8.

Effects of nicotinic acetylcholine receptor agonists on cognition in rhesus monkeys with a chronic cocaine self-administration history. Gould RW, Garg PK, Garg S, Nader MA.. Neuropharmacology. 2013;64(1):479-488.

Effects of dopamine D2/D3 receptor ligands on food-cocaine choice in socially housed male cynomolgus monkeys. Czoty PW, Nader MA.. J Pharmacol Exp Ther. 2013;344(2):329-338.

The relationship between cocaine self-administration and actigraphy-based measures of sleep in adult rhesus monkeys. Brutcher RE, Nader MA.. Psychopharmacology (Berl). 2013;229(2):267-274.

Examining the relationship between cocaine and sleep in a monkey model of drug abuse [abstract]. Brutcher R, Nader M.. FASEB J. 2013;27():659.2.

Effects of chronic methylphenidate on cocaine self-administration under a progressive-ratio schedule of reinforcement in rhesus monkeys. Czoty PW, Martelle SE, Gould RW, Nader MA.. J Pharmacol Exp Ther. 2013;345(3):374-382.

The role of dopamine D3 receptors in the discriminative stimulus effects of quinpirole, cocaine, and methamphetamine in rhesus monkeys [abstract]. Duke AN, Green HL, Newman AH, Nader MA.. FASEB J. 2013;27():659.4.

Further characterization of varenicline (VAR) and mecamylamine (MEC) and effects on self-administration (SA) of cocaine (COC) and nicotine (NIC) [abstract]. Kromrey SA, Nader S, Nader M.. FASEB J. 2013;27():1098.9.

The relative reinforcing strength of methamphetamine and D-amphetamine in monkeys self-administering cocaine. Lile JA, Charnigo RJ, Nader MA.. Behav Pharmacol. 2013;24(5-6):482-485.

Effects of chronic methylphenidate in adolescence on later methylphenidate self-administration in rhesus monkeys. Martelle SE, Porrino LJ, Nader MA.. Behav Pharmacol. 2013;24(5-6):478-481.

Obituary: William L. Woolverton [obituary]. Balster RL, Nader MA, Freeman KB.. Psychopharmacology (Berl). 2013;229(2):379-381.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

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