Marina Nunez, M.D., Ph.D.Wake Forest Baptist Health

Doctor Rating

4.6 out of 5

55 Ratings

Marina Nunez, M.D., Ph.D.

Associate Professor,

Clinical Interests

Infectious Diseases, Hepatitis B, Hepatitis C

Contact Information

New Patient Appointments: 336-716-WAKE
Returning Patient Appointments: 336-716-2700
Department: 336-716-2700

Insurance Accepted »

Additional Languages


Education & Training

  • M.D., Univ Navarra Faculty of Medicine-Spain, 1988
  • Ph.D., Univ Navarra Faculty of Medicine-Spain, 1996
  • Residency, Internal Medicine, Univ Navarra Faculty of Medici, 1994
  • Fellowship, Infectious Disease, WFU School of Medicine, 1998

Board Certifications

  • American Board of Internal Medicine, Infectious Disease
  • American Board of Internal Medicine, Internal Medicine

NPI Number

  • 1700815479
Marina Nunez, M.D., Ph.D.

Doctor Rating

4.6 out of 5

55 Ratings

Marina Nunez, M.D., Ph.D.

Associate Professor, Infectious Diseases

Research Interests

infectious diseases, minority health issues

Contact Information

Academic: 336-716-4512 | Department: 336-716-2700

Recent Publications

Huang AJ, Nunez M. Outcomes in HIV-HBV-coinfected patients in the tenofovir era are greatly affected by immune suppression. J Int Assoc Provid AIDS Care. 2015;14(4):360-368.

Gomes Martins de Moura Tomich L, Nunez M, Mendes-Correa MC. Drug-induced liver injury in hospitalized HIV patients: high incidence and association with drugs for tuberculosis. Ann Hepatol. 2015;14(6):888-894.

Shores NJ, Mendes-Correa MC, Maida I, Turner J, High KP, Babudieri S, Nunez M. Hepatic peroxisome proliferator-activated receptor gamma and alpha-mRNA expression in HCV-infected adults is decreased by HIV co-infection and is also affected by ethnicity. Clinics (Sao Paulo). 2015;70(12):790-796.

Kikuchi L, Citti CC, Chen TY, Platt HL, Kaplan DE, Vetura-Cots M, Jain MK, Vispo E, Daruich J, Nunez M, Barreiro P, Minguez B, Aytaman A, Rimland D, Brau N. Sorafenib therapy in HIV-infected patients with hepatocellular carcinoma (HCC) [abstract]. Hepatology. 2015;62(Suppl 1):430A.

Barbour S, Bachmann L, Nunez M. Transient hepatitis B surface antigenemia after hepatitis B virus vaccine in an HIV-infected patient [letter]. AIDS Res Hum Retroviruses. 2013;29(4):639-640.

Nunez M, Mendes-Correa MC. Viral hepatitis and HIV: update and management. Antivir Ther. 2013;18(3 Pt B):451-458.

Oppenheimer AP, Johnson J, Nunez M. Outcome of HCV genotype 1 treatment in HIV-coinfected patients with chronic kidney disease. J Int Assoc Provid AIDS Care. 2013;12(1):55-57.

Price H, Dunn D, Pillay D, Bani-Sadr F, de Vries-Sluijs T, Jain MK, Kuzushita N, Mauss S, Nunez M, Nuesch R, Peters M, Reiberger T, Stephan C, Tan L, Gilson R. Suppression of HBV by tenofovir in HBV/HIV coinfected patients: a systematic review and meta-analysis. PLoS One. 2013;8(7):e68152.

Divers J, Nunez M, High KP, Murea M, Rocco MV, Ma L, Bowden DW, Hicks PJ, Spainhour M, Ornelles DA, Kleiboeker SB, Duncan K, Langefeld CD, Turner J, Freedman BI. JC polyoma virus interacts with APOL1 in African Americans with nondiabetic nephropathy. Kidney Int. 2013;84(6):1207-1213.

Nguyen V, Nunez M. Poor correlation between ALT normalization and virological response to hepatitis C treatment [abstract]. Am J Gastroenterol. 2013;108(Suppl 1):S149.

Rockstroh JK, Nelson M, Soriano V, Arasteh K, Guardiola JM, Bhagani S, Mallolas J, Tural C, Puoti M, Ingliz P, Battegay M, Jain MK, Nunez M, Marks KM, Kort JJ, Stern JO, Vinisko R, Manero M, Dieterich DT. STARTVerso 4 Phase III trial of faldaprevir plus peg interferon alfa-2a and ribavirin (PR) in patients with HIV and HCV genotype 1 coinfection: end of treatment response [abstract]. Hepatology. 2013;58(Suppl 1):741A-742A.

Jain MK, Kikuchi LO, Minguez B, Ventura M, Vispo E, Chen TY, Badshah MB, Page EE, Taylor LE, Marks KM, Nunez M, Hernandez MD, Jalali Z, Palys E, Qazi N, Harris M, Fox RK, Aytaman A, Aberg J, Brau N. MESIAH score, BCLC, and other staging models as predictors of survival of hepatocellular carcinoma in HIV-infected patients [abstract]. Hepatology. 2013;58(Suppl 1):1248A-49A.

Jones M, Nunez M. Liver toxicity of antiretroviral drugs. Semin Liver Dis. 2012;32(2):167-176.

Freedman BI, Langefeld CD, Turner J, Nunez M, High KP, Spainhour M, Hicks PJ, Bowden DW, Reeves-Daniel AM, Murea M, Rocco MV, Divers J. Association of APOL1 variants with mild kidney disease in the first-degree relatives of African American patients with non-diabetic end-stage renal disease. Kidney Int. 2012;82(7):805-811.

Lamar ZS, Nunez M. Higher risk of severe drug-induced liver injury among Hispanic HIV-infected patients after initiation of highly active antiretroviral therapy. J Int Assoc Physicians AIDS Care (Chic Ill). 2011;10(3):183-186.

Connoy A, Turner J, Nunez M. Levels of serum markers of liver inflammation and fibrosis in patients with chronic hepatitis C virus infection according to HIV status and antiretroviral use. AIDS Res Hum Retroviruses. 2011;27(7):719-725.

Jones M, Nunez M. HIV and hepatitis C co-infection: the role of HAART in HIV/hepatitis C virus management. Curr Opin HIV AIDS. 2011;6(6):546-552.

Shores N, Mendes-Correa MC, Maida I, Turner J, Uip DE, High K, Nunez M. Hepatic PPAR gamma expression is further impaired in HCV-infected subjects with HIV-co-infection [abstract]. Hepatology. 2011;54(Suppl 1):1331A.

Nunez M, Saran AM, Freedman BI. Gene-gene and gene-environment interactions in HIV-associated nephropathy: a focus on the MYH9 nephropathy susceptibility gene. Adv Chronic Kidney Dis. 2010;17(1):44-51.

Shores NJ, Maida I, Perez-Saleme L, Nunez M. Virological rather than host factors are associated with transaminase levels among HIV/HCV-coinfected patients. J Int Assoc Physicians AIDS Care (Chic Ill). 2010;9(1):15-19.

Nunez M. Routine hepatitis B virus DNA testing in human immunodeficiency virus-infected patients with positive hepatitis B core antibody but negative hepatitis B surface antigen is not justified by current evidence [letter]. Hepatology. 2010;51(3):1087-1088.

Brau N, Kikuchi L, Nunez M, Barreiro P, Nelson M, Bini EJ, Kristen M, Fox R, Sherman M, Puoti M. Improved survival of hepatocellular carcinoma (HCC) in HIV-infected patients with undetectalbe HIV RNA [abstract]. J Hepatol. 2010;52(Suppl 1):S219.

Kikuchi L, Nunez M, Barreiro P, Nelson M, Vispo ME, Page E, Puoti M, Fox R, Sherman M, Carrilho F, et al. Impact of screening for hepatocellular carcinoma (HCC) in HIV/HCV-coinfected patients on staging, therapy and survival [abstract]. J Hepatol. 2010;52(Suppl 1):S412.

Nunez M. Clinical syndromes and consequences of antiretroviral-related hepatotoxicity. Hepatology. 2010;52(3):1143-1155.

Mendes-Correa M, Nunez M. Management of HIV and hepatitis virus coinfection. Expert Opin Pharmacother. 2010;11(15):2497-2516.

Kaplan DE, Daruich J, Jalali Z, Rafiullah, Nunez M, Vogel M, Vispo E, Barreiro P, Rockstroh JK, Mauss S, et al. Age and hepatocellular carcinoma in HIV-infected patients [abstract]. Hepatology. 2010;52(4 Suppl):1174-5A.

Lee T, Nunez M. Longer duration of HBV-active antiretroviral therapy is linked to favorable virological outcome in HIV-HBV co-infected patients. HIV Clin Trials. 2009;10(3):153-159.

Townsend D, Troya J, Maida I, Perez-Saleme L, Satta G, Wilkin A, Barreiro P, Pegram PS, Soriano V, Nunez M, et al. First HAART in HIV-infected patients with high viral load: value of HIV RNA levels at 12 weeks to predict virologic outcome. J Int Assoc Physicians AIDS Care (Chic Ill). 2009;8(5):314-317.

Nunez M, Beltz A, High K. Effect of HIV on levels of serum markers of liver inflammation and fibrosis in hepatitis C virus co-infection [abstract]. Hepatology. 2009;50(4 Suppl):923A-924A.

Maida I, Rios MJ, Perez-Saleme L, Ramos B, Soriano V, Pegram PS, Mura MS, Sanchez-Margalet V, Wilkin A, Nunez M, et al. Profile of patients triply infected with HIV and the hepatitis B and C viruses in the HAART era. AIDS Res Hum Retroviruses. 2008;24(5):679-683.

Yacisin K, Maida I, Rios MJ, Soriano V, Nunez M. Hepatitis C virus coinfection does not affect CD4 restoration in HIV-infected patients after initiation of antiretroviral therapy. AIDS Res Hum Retroviruses. 2008;24(7):935-940.

Shores NJ, Maida I, Soriano V, Nunez M. Sexual transmission is associated with spontaneous HCV clearance in HIV-infected patients. J Hepatol. 2008;49(3):323-328.

Soriano V, Rivas P, Nunez M. Risks and benefits of using antiretroviral therapy in HIV-infected patients with chronic hepatitis B in developing regions [editorial]. Clin Infect Dis. 2008;47(11):1486-1489.

Nunez M. Response to Cicconi et al. 'Is the increased risk of liver enzyme elevation in patients co-infected with HIV and hepatitis virus greater in those taking antiretroviral therapy?' [letter]. AIDS. 2007;21(12):1660.

Nunez M, Miralles C, Berdun MA, Losada E, Aguirrebengoa K, Ocampo A, Arazo P, Cervantes M, De Los Santos I, San Joaquin I, et al. Role of weight-based ribavirin dosing and extended duration of therapy in chronic hepatitis C in HIV-infected patients: the PRESCO Trial. AIDS Res Hum Retroviruses. 2007;23(8):972-982.

Nunez M, Soriano V, Lopez M, Ballesteros C, Cascajero A, Gonzalez-Lahoz J, Benito JM. Coinfection with hepatitis C virus increases lymphocyte apoptosis in HIV-infected patients [editorial]. Clin Infect Dis. 2006;43(9):1209-1212.

Nunez M, Ramos B, Diaz-Pollan B, Camino N, Martin-Carbonero L, Barreriro P, Gonzalez-Lahoz J, Soriano V. Virological outcome of chronic hepatitis B virus infection in HIV-coinfected patients receiving anti-HBV active antiretroviral therapy. AIDS Res Hum Retroviruses. 2006;22(9):842-848.

Maida I, Soriano V, Castellares C, Ramos B, Sotgiu G, Martin-Carbonero L, Barreiro P, Rivas P, Gonzalez-Lahoz J, Nunez M. Liver fibrosis in HIV-infected patients with chronic hepatitis B extensively exposed to antiretroviral therapy with anti-HBV activity. HIV Clin Trials. 2006;7(5):246-250.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Associate Professor, Infectious Diseases

Clinical Interests

Infectious Diseases, Hepatitis B, Hepatitis C
Marina Nunez, M.D., Ph.D.

Marina Nunez, M.D., Ph.D.

Associate Professor, Infectious Diseases

Doctor Rating

4.6 out of 5

Marina Nunez, M.D., Ph.D.55 Ratings


Doctor Ratings

The overall Patient Rating score is the average of responses to the nine questions listed below. The questions are from the Press Ganey Patient Satisfaction Survey. Responses are measured on a 1 to 5 scale, where 1 represents "very poor" and 5 represents "very good."
Press Ganey Patient Satisfaction Survey

CP concern for questions/worries
CP efforts to include in decisions
CP explanations of prob/condition
CP spoke using clear language
Friendliness/courtesy of CP
Likelihood of recommending CP
Patients' confidence in CP
Time CP spent with patient
Wait time at clinic

Patient Comments

Comments are taken from the Care Provider section of the Press Ganey Patient Satisfaction Survey. Comments are posted exactly as they are written. Comments are added weekly. To protect patient privacy and confidentiality, patient names are not included.


Practical provider and very good.


Very good and informative.


I just always feel rushed by doctor. And the last visit, she seemed to be in a hurry I had questions & concerns.


The doctor was very thorough in explaining everything about my condition.


Wonderful doctor and human being! She was more like a friend to me.


My provider seemed predominately interested in gazing @ the computer and ordering tests.

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