Francis X. O'Brien, M.D.Wake Forest Baptist Health

Doctor Rating

4.8 out of 5

245 Ratings

Francis X. O'Brien, M.D.

Assistant Professor,

Clinical Locations

University Internal Medicine - Country Club

Clinical Specialties

General Internal Medicine

Contact Information

New Patient Appointments: 336-716-WAKE
Returning Patient Appointments: 336-716-3787
Department: 336-716-6157

Insurance Accepted »

Education & Training

  • B.S., Yale University , 1981
  • M.D., Temple University School of Medicine , 1985
  • Residency, Internal Medicine, Cooper Med Ctr, 1988

Board Certifications

  • American Board of Internal Medicine, Internal Medicine - Internal Medicine


  • North Carolina Medical Society
  • Am Medical Assn
  • Forsyth County Medical Society
  • Forsyth-Davie-Stokes Medical S

NPI Number

  • 1558348441
Francis X. O'Brien, M.D.

Doctor Rating

4.8 out of 5

245 Ratings

Francis X. O'Brien, M.D.

Assistant Professor, General Internal Medicine

Contact Information

Academic: 336-716-3787 | Department: 336-716-6157

Recent Publications

Upadhya B, Ntim W, Brandon Stacey R, Henderson R, Leedy D, O'Brien FX, Knovich MA. Prolongation of QTc intervals and risk of death among patients with sickle cell disease. Eur J Haematol. 2013;91(2):170-178.

Upadhya B, Ntim W, Dworkin J, Leedy D, O'Brien FX, Connor R, Cruz JM. Prolongation of QTc intervals and risk of sudden death among patients with sickle cell diseases [abstract]. Blood. 2007;110(11 Pt 1):667A.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Assistant Professor, General Internal Medicine

Clinical Specialties

General Internal Medicine
Francis X. O'Brien, M.D.

Francis X. O'Brien, M.D.

Assistant Professor, General Internal Medicine

Doctor Rating

4.8 out of 5

Francis X. O'Brien, M.D.245 Ratings

Doctor Ratings

The overall Patient Rating score is the average of responses to the nine questions listed below. The questions are from the Press Ganey Patient Satisfaction Survey. Responses are measured on a 1 to 5 scale, where 1 represents "very poor" and 5 represents "very good."
Press Ganey Patient Satisfaction Survey

CP concern for questions/worries
CP efforts to include in decisions
CP explanations of prob/condition
CP spoke using clear language
Friendliness/courtesy of CP
Likelihood of recommending CP
Patients' confidence in CP
Time CP spent with patient
Wait time at clinic

Patient Comments

Comments are taken from the Care Provider section of the Press Ganey Patient Satisfaction Survey. Comments are posted exactly as they are written. Comments are added weekly. To protect patient privacy and confidentiality, patient names are not included.


*Dr. O'Brien does the most extensive exam of any doctor I have ever been to.


My care provider is excellent in all ways


My physician is always courteous and easy to talk with. My confidence is him is reflected in the time I have kept him as my primary care physician (I see at least 6 other physicians at WFUP).


Care was given immediately.


Dr. O'Brien is an excellent, caring physician.


I have recommended Dr O'Brien to others


provider is the best!!


This doctor is not my regular doctor. But if I ever wanted a new doctor or one to fill in again , I would most assuredly choose this one (Dr. O Brien). He was unbelievable.. I and my husband truly appreciate his attention and concern.


I have never had a more through physician!


*Dr. O'Brien is also my oldest son's doctor, and husband's until his death.


Dr. O'Brien has gone out of his way to show his concern for my health. He has called me at night (between appointments) to check on my health.


I have been going to Dr. O'Brien's office for years and I've always been treated well. I would recommend anyone to have Dr. O'Brien as their doctor.


Dr. O'Brien is the best Dr. I have seen in my 75 years. He is a very caring Dr., he goes the extra mile in ways such as calling to pass on results of tests, checking to see if your condition has improved after he had treated me for sickness.


This provider has always been a great caring professional.


Dr. O'Brien does a great job in asking and answering questions regarding my health. He is thorough and always easy to talk to. I would highly recommend him.


Dr. OBrien is fabulous


Although I have had good doctors in the past, Dr. O'Brien is by far the best. He is wonderful. I recommend him to anyone I hear is looking for a doctor.




dr. O'Brien is one of the most perceptive, well prepared physicians I've ever met. he has sorted some incredibly complex issues for my wife. He, by virtue of his extraordinary effort, close supervision, and thoroughly care of my wife's multiple illnesses has directly saved her life on three occasions.


Excellant, knowledgable, thorough, caring physician.


All my visit was with Dr. O'Brien except blood pressure--so all is good


He is the BEST


I have already recommended Dr. O'Brien to another person


*Dr. Francis O'Brien is an outstanding DOCTOR.

Quick Reference

Request an Appointment
New Patients


Existing patients may contact the clinic directly.
Find a Doctor Ways to Give
USNWR 2013-2014Magnet Hospital RecognitionConsumer Choice2014 Best DoctorsJoint Commission Report

Disclaimer: The information on this website is for general informational purposes only and SHOULD NOT be relied upon as a substitute for sound professional medical advice, evaluation or care from your physician or other qualified health care provider.