Francis X. O'Brien, M.D.Wake Forest Baptist Health

Doctor Rating

4.9 out of 5

346 Ratings

Francis X. O'Brien, M.D.

Assistant Professor,

Clinical Locations

University Internal Medicine - Country Club

Clinical Interests

General Internal Medicine

Contact Information

New Patient Appointments: 336-716-WAKE
Returning Patient Appointments: 336-716-3787
Department: 336-716-3787

Insurance Accepted »

Education & Training

  • B.S., Yale University, 1981
  • M.D., Temple University School of Medicine, 1985
  • Residency, Internal Medicine, Cooper Med Ctr, 1988

Board Certifications

  • American Board of Internal Medicine, Internal Medicine


  • Am Medical Assn
  • Forsyth County Medical Society
  • Forsyth-Davie-Stokes Medical S
  • North Carolina Medical Society

NPI Number

  • 1558348441
Francis X. O'Brien, M.D.

Doctor Rating

4.9 out of 5

346 Ratings

Francis X. O'Brien, M.D.

Assistant Professor, General Internal Medicine

Contact Information

Academic: 336-716-3787 | Department: 336-716-3787

Recent Publications

Upadhya B, Ntim W, Brandon Stacey R, Henderson R, Leedy D, O'Brien FX, Knovich MA. Prolongation of QTc intervals and risk of death among patients with sickle cell disease. Eur J Haematol. 2013;91(2):170-178.

Upadhya B, Ntim W, Dworkin J, Leedy D, O'Brien FX, Connor R, Cruz JM. Prolongation of QTc intervals and risk of sudden death among patients with sickle cell diseases [abstract]. Blood. 2007;110(11 Pt 1):667A.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Assistant Professor, General Internal Medicine

Clinical Interests

General Internal Medicine
Francis X. O'Brien, M.D.

Francis X. O'Brien, M.D.

Assistant Professor, General Internal Medicine

Doctor Rating

4.9 out of 5

Francis X. O'Brien, M.D.346 Ratings


Doctor Ratings

The overall Patient Rating score is the average of responses to the nine questions listed below. The questions are from the Press Ganey Patient Satisfaction Survey. Responses are measured on a 1 to 5 scale, where 1 represents "very poor" and 5 represents "very good."
Press Ganey Patient Satisfaction Survey

CP concern for questions/worries
CP efforts to include in decisions
CP explanations of prob/condition
CP spoke using clear language
Friendliness/courtesy of CP
Likelihood of recommending CP
Patients' confidence in CP
Time CP spent with patient
Wait time at clinic

Patient Comments

Comments are taken from the Care Provider section of the Press Ganey Patient Satisfaction Survey. Comments are posted exactly as they are written. Comments are added weekly. To protect patient privacy and confidentiality, patient names are not included.


Always excellent


In my 50+ years of seeing different types physicians in different places, I have found Dr. Francis O'Brien to be the best. He is concerned about my wellbeing, explains all topics in a way I can understand, treats me with extreme courtesy while being very professional. If all the physicians all as caring as Dr. O'Brien, the world will be healthier and happier!




Fran Obrien is the best in my opinion and he runs the same office.


Dr. Obrien has always been very attentive to my needs.


Dr. O'Brien is the very best. I often tell my friends about how communicative he is... he always takes the time needed during an office visit. He often calls at the end of the day to check on his patients. He replies to emails speedily. He is always available - and that is unusual - and I appreciate it.


Excellent, caring physician who is always thorough in his history taking and physical exam, as well as with providing detailed explanations regarding diagnosis and treatment.


I think that I made a very good choice on healthcare provider.


diagnosed with human metapneumovirus which led to pneumonia. everyone in the office was very caring and helpful.


*Dr. O'Brien is the best!!!


Very satisfied.


Dr. Obrien is an excellent physician and a wonderful person


Excellent physician


All my experiences with *Dr. O'Brien have been excellent!


Very happy with Dr. O'Brien. Very professional and helpful with any and all questions I have.


Dr O'Brien is genuinely caring and concerned. He has helped me tremendously over the past few years.


Always the very best!!!


Dr. O'Brien has been my doctor for years and I trust him completely. He is very thorough, kind, and is concerned with both my physical and mental health. I would never go to another primary care physician as long as Dr. O'Brien is practicing medicine. He is the very best.


This was my first visit to Dr. O'Brien and consisted of an annual physical. Dr. O'Brien spent almost an hour going over my general health and the list of "concerns" I brought with me.


Expressed multiple concerns. Not all were addressed.


I gave "very good" ratings after careful thought. I don't take surveys lightly.


*Dr. O'Brien is an excellent physician.


In my working career, I moved quite often so I was treated by numerous doctors over a 40 year period. Of all the doctors I have seen in those years, Dr. O'Brien is head and shoulders above them all. He is, simply put, the best doctor on the planet!


Excellent Physician


Dr O is caring considerate and a great doc....


So far so good.


Dr. O'Brien is an excellent provider. He is very thorough. He listens to the patient and carefully reads the patient chart as well as review it with the patient. He is courtesy and caring and expresses genuine interest in his patients. His bed side manner is one of the best I've encountered throughout my life. He's an asset to Wake Forest, his patients and to all who know him. We need more providers like Dr. O'Brien.


I always recommend my provider to my family and friends


Excellent experience


Dr. O'Brien is a top-notch physician, caring and capable. I appreciate the personal attention he gives.


Anyone would be fortunate to have this care provider.


Dr O'Brien is a marvelous and caring physician. He cares for me and I know many of his other patients who respect his ability as I do. He is like a son to me. Most professional but caring. Wise but kind.I love his manner and would recommend him to anyone. He is a delight to know and I am happy he cares for me so well!!!!


Dr Obrien is one of the best


In all respects, very good.


One of your best PCP's


Very good.


dr. obrien is one of the best doctors I've had.


love him


No bad experiences.


Dr. O'Brien provides excellent care; he is very thorough and thoughtful and is a very caring individual.


Dr. O'Brien is a very caring physician. He provides excellent and compassionate care for me.


Keenly intelligent doctor, caring, concerned & good sense of humor!


I have never had as much confidence in my personal physician as I do in Dr. O'Brien


Dr. O'Brien is the best most thorough doctor ever. I trust him with my life!


*Dr. O'Brien also sees my mother, husband AND son. He is a wonderful dr.! VERY RESPECTFUL.


Have recommended this dr. to my brother/sister-in-law. Both patients of his now.


The care provided was *Dr. O'Brien & I didn't had any bad experience. He is a very good dr., & I could tell he is with great concern for his patients.


Dr. O'Brien is an excellent physician. He is courteous, friendly, thorough and always willing to listen and discuss any medical questions or concerns I may have. I would highly recommend him to any friend or family member. Wake Health is fortunate to have Dr. O'Brien on their staff.


Dr. O'Brien is thoughtful, professional, and compassionate; shares his knowledge, communicates well. He is a great physician.


Dr O'Brien is a great doctor and a professional in every sense. He has been proactive in addressing my needs.


Dr Obrien is the best doctor, I've had, and very understanding.


Dr. O'Brien is an excellent, caring physician. He takes time to listen to any problems and then solves them if possible.


Dr. O'Brien is an ideal doctor in that he is knowledge and caring.




Dr. O'Brien has been my primary care provider for many years. Before seeing him, I had been to many physicians. I struggled with an undiagnosed medical condition. Dr. O'Brien took over my health care and diagnosed my problem. I am very pleased with the excellent care I receive and the improvement of my health since seeing Dr. O'Brien.


Dr. O'Brien seems to be a person who cares about his patients. He does not mince words when instructing you about ways to live a healthier life (he never fails to let me know that I need to quit smoking and the risks that I'm taking in doing so). I like that in a doctor.


Dr. O'Brien is an excellent physician. He listens to his patients and spends as much time with them as they require.


Dr. O'Brien seems to really CARE about my health and explains things in easy to understand terms. He is the best doctor I've had in my 80 years of going to a doctor!


*Dr. O'Brien is excellent!

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