Francis X. O'Brien, M.D.Wake Forest Baptist Health

Doctor Rating

4.9 out of 5

337 Ratings

Francis X. O'Brien, M.D.

Assistant Professor,

Clinical Locations

University Internal Medicine - Country Club

Clinical Interests

General Internal Medicine

Contact Information

New Patient Appointments: 336-716-WAKE
Returning Patient Appointments: 336-716-3787
Department: 336-716-3787

Insurance Accepted »

Education & Training

  • B.S., Yale University, 1981
  • M.D., Temple University School of Medicine, 1985
  • Residency, Internal Medicine, Cooper Med Ctr, 1988

Board Certifications

  • American Board of Internal Medicine, Internal Medicine


  • North Carolina Medical Society
  • Am Medical Assn
  • Forsyth County Medical Society
  • Forsyth-Davie-Stokes Medical S

NPI Number

  • 1558348441
Francis X. O'Brien, M.D.

Doctor Rating

4.9 out of 5

337 Ratings

Francis X. O'Brien, M.D.

Assistant Professor, General Internal Medicine

Contact Information

Academic: 336-716-3787 | Department: 336-716-3787

Recent Publications

Prolongation of QTc intervals and risk of death among patients with sickle cell disease. Upadhya B, Ntim W, Brandon Stacey R, Henderson R, Leedy D, O'Brien FX, Knovich MA.. Eur J Haematol. 2013;91(2):170-178.

Prolongation of QTc intervals and risk of sudden death among patients with sickle cell diseases [abstract]. Upadhya B, Ntim W, Dworkin J, Leedy D, O'Brien FX, Connor R, Cruz JM.. Blood. 2007;110(11 Pt 1):667A.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Assistant Professor, General Internal Medicine

Clinical Interests

General Internal Medicine
Francis X. O'Brien, M.D.

Francis X. O'Brien, M.D.

Assistant Professor, General Internal Medicine

Doctor Rating

4.9 out of 5

Francis X. O'Brien, M.D.337 Ratings


Doctor Ratings

The overall Patient Rating score is the average of responses to the nine questions listed below. The questions are from the Press Ganey Patient Satisfaction Survey. Responses are measured on a 1 to 5 scale, where 1 represents "very poor" and 5 represents "very good."
Press Ganey Patient Satisfaction Survey

CP concern for questions/worries
CP efforts to include in decisions
CP explanations of prob/condition
CP spoke using clear language
Friendliness/courtesy of CP
Likelihood of recommending CP
Patients' confidence in CP
Time CP spent with patient
Wait time at clinic

Patient Comments

Comments are taken from the Care Provider section of the Press Ganey Patient Satisfaction Survey. Comments are posted exactly as they are written. Comments are added weekly. To protect patient privacy and confidentiality, patient names are not included.


He's been my PCP for over 15 years and I hope to continue under his care for years to come!!!


*Dr. O'Brien is the best. He is caring, knowledgeable, takes time to check record, be sure of info. I trust him.


Best doctor you could have for general health.


I live in Greensboro, NC and I believe Wake Forest is the very best in both Winston Salem & Greensboro. I in the past in GREENSBORO - had doctors to give me incorrect information about DEATTACHED RETINA - left eye almost lost my eye. #9. I have seen him every year for 15 yrs.


Dr. O'Brien is an excellent physician.


Dr. O'Brien is an excellent doctor. He is courteous, friendly, thorough and attentive to all my medical needs. He always provides me with updated information regarding my health and medications. He is a consummate professional and I would highly recommend him to anyone who is in need of a primary care physician.


Dr. O'Brien is an exceptional primary care physician. He goes out of his way to help and show his concern.


Sincerely believe I have best working relationship with *Dr. O'Brien of any doctor I have ever dealt with. He listens and works to help solve any problems, not just prescribe a pill or brush it aside. I trust him implicitly with my health care, that he will correctly guide me to living and maintain good health, life stay as I grow older.


Dr. O'Brien is the best doctor in the US. I trust him completely with my physical/mental care.


great doctor


I have been to a lot of drs. in my lifetime, *Dr. O'Brien was more concerned with my health than any dr. I have ever visited.


Dr O'Brien is my primary care physcian - my "quarterback" for the Wake Forest medical team. He is an excellent physician and an excellent team leader. He smoothly coordinates the services of other doctors and testing facilities at Wake. He communicates and interprets my test results in a remarkably short period of time. I feel like I am in good hands with Doctor O'Brien


I think very highly of Dr O'Brien and would definitely reccommend him


I almost never give all 5s, but Dr. O'Brien is the best!


Dr. O'Brien is is very caring and an extraordinary provider.


The best.


Very good.


They don't come any better than Dr. O'Brien!


I feel fortunate to have *Dr. O'Brien as my health care provider.


he's amazing as a doctor and a person


Dr. O'Brien is very thorough and a caring physician.


I have been a patient of Dr. OBrien for approx 10 years. He has always been concerned about my health and well being. He helped me quit smoking. He has always been helpful with any problem that I might have.


Very good.


Always treated well. Always listed to.


I have all the confidence in world for *Dr. O'Brien.


Dr. O'Brien is a thoughtful listener and responds to all my questions. He mentions things I might have forgotten to bring up and this is very helpful.


Physician was very thorough.


Excellent Doctor!


Dr. Obrien is always thorough and friendly. I feel like he truly cares and pays attention. thank you.


Dr. Obrien is a very compassionate doctor. I could not ask for a better doctor.


Always excellent


In my 50+ years of seeing different types physicians in different places, I have found Dr. Francis O'Brien to be the best. He is concerned about my wellbeing, explains all topics in a way I can understand, treats me with extreme courtesy while being very professional. If all the physicians all as caring as Dr. O'Brien, the world will be healthier and happier!




Fran Obrien is the best in my opinion and he runs the same office.


Dr. Obrien has always been very attentive to my needs.


Dr. O'Brien is the very best. I often tell my friends about how communicative he is... he always takes the time needed during an office visit. He often calls at the end of the day to check on his patients. He replies to emails speedily. He is always available - and that is unusual - and I appreciate it.


Excellent, caring physician who is always thorough in his history taking and physical exam, as well as with providing detailed explanations regarding diagnosis and treatment.


I think that I made a very good choice on healthcare provider.


diagnosed with human metapneumovirus which led to pneumonia. everyone in the office was very caring and helpful.


*Dr. O'Brien is the best!!!


Very satisfied.


Dr. Obrien is an excellent physician and a wonderful person


Excellent physician


All my experiences with *Dr. O'Brien have been excellent!


Very happy with Dr. O'Brien. Very professional and helpful with any and all questions I have.


Dr O'Brien is genuinely caring and concerned. He has helped me tremendously over the past few years.


Always the very best!!!


Dr. O'Brien has been my doctor for years and I trust him completely. He is very thorough, kind, and is concerned with both my physical and mental health. I would never go to another primary care physician as long as Dr. O'Brien is practicing medicine. He is the very best.


This was my first visit to Dr. O'Brien and consisted of an annual physical. Dr. O'Brien spent almost an hour going over my general health and the list of "concerns" I brought with me.


Expressed multiple concerns. Not all were addressed.


I gave "very good" ratings after careful thought. I don't take surveys lightly.


*Dr. O'Brien is an excellent physician.


In my working career, I moved quite often so I was treated by numerous doctors over a 40 year period. Of all the doctors I have seen in those years, Dr. O'Brien is head and shoulders above them all. He is, simply put, the best doctor on the planet!


Excellent Physician


Dr O is caring considerate and a great doc....


So far so good.


Dr. O'Brien is an excellent provider. He is very thorough. He listens to the patient and carefully reads the patient chart as well as review it with the patient. He is courtesy and caring and expresses genuine interest in his patients. His bed side manner is one of the best I've encountered throughout my life. He's an asset to Wake Forest, his patients and to all who know him. We need more providers like Dr. O'Brien.


I always recommend my provider to my family and friends


Excellent experience


Dr. O'Brien is a top-notch physician, caring and capable. I appreciate the personal attention he gives.


Anyone would be fortunate to have this care provider.


Dr O'Brien is a marvelous and caring physician. He cares for me and I know many of his other patients who respect his ability as I do. He is like a son to me. Most professional but caring. Wise but kind.I love his manner and would recommend him to anyone. He is a delight to know and I am happy he cares for me so well!!!!

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