T. Michael D O'Shea, M.D.Wake Forest School of Medicine

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T. Michael D O'Shea, M.D.

Vice Chair,

Clinical Interests

Neonatology, Epidemiology

Contact Information

New Patient Appointments: 336-716-WAKE
Returning Patient Appointments: 336-716-4663
Department: 336-716-4663


Insurance Accepted »

Education & Training

  • B.A., University of North Carolina-Chapel Hill, 1974
  • M.D., University of North Carolina School of Medicine, 1980
  • M.P.H., University of North Carolina School of Public Hlth, 1990
  • Internship, Pediatrics, North Carolina Mem Hosp, 1981
  • Residency, Neonata/Perinatal Medicine, North Carolina Mem Hosp, 1984
  • Fellowship, Duke University Hospital, 1986

Board Certifications

  • American Board of Internal Medicine, Internal Medicine
  • American Board of Pediatrics, Pediatrics
  • American Board of Pediatrics, Pediatrics, Neonata/Perinatal Medicine


  • Am Academy Of Pediatrics
  • Soc Of Pediatric Research
  • Soc for Perinat & Ped Epid Res
  • Am Pediatric Society
  • Am Acad Of Cer Palsy & Dev Med

NPI Number

  • 1356325351
T. Michael D O'Shea, M.D.

Doctor Rating

No Rating Available
Why No Ratings?

T. Michael D O'Shea, M.D.

Vice Chair, Pediatrics
Professor, Pediatrics
Hypertension and Vascular Research Center
Epidemiology & Prevention
Social Sciences & Health Policy

Research Interests

cognition/learning, critical/intensive care medici, drugs/therapeutic agents pharm, epidemiology, genomics and proteomics, growth & development, hormones/cytokines/signalling, maternal & child health, neurosciences/behavior

Contact Information

Academic: 336-716-6097 | Department: 336-716-4663


Recent Publications

Downey LC, O'Shea TM, Allred EN, Kuban K, McElrath TF, Warner DD, Ware J, Hecht JL, Onderdonk A, Leviton A. Antenatal and early postnatal antecedents of parent-reported attention problems at 2 years of age. J Pediatr. 2015;166(1):20-25.

Kuban KC, O'Shea TM, Allred EN, Fichorova RN, Heeren T, Paneth N, Hirtz D, Dammann O, Leviton A. The breadth and type of systemic inflammation and the risk of adverse neurological outcomes in extremely low gestation newborns. Pediatr Neurol. 2015;52(1):42-48.

Stefanescu BM, Frewan N, Slaughter JC, O'Shea TM. Volume guarantee pressure support ventilation in extremely preterm infants and neurodevelopmental outcome at 18 months. J Perinatol. 2015;35(6):419-423.

Korzeniewski SJ, Allred E, Logan JW, Fichorova RN, Engelke S, Kuban KC, O'Shea TM, Paneth N, Holm M, Dammann O, Leviton A. Elevated endogenous erythropoietin concentrations are associated with increased risk of brain damage in extremely preterm neonates. PLoS One. 2015;10(3):e0115083.

Washburn LK, Nixon PA, Russell GB, Snively BM, O'Shea TM. Preterm birth is associated with higher uric acid levels in adolescents. J Pediatr. 2015;167(1):76-80.

van der Burg JW, Allred EN, Kuban K, O'Shea TM, Dammann O, Leviton A. Maternal obesity and development of the preterm newborn at 2 years. Acta Paediatrica. 2015;():.

Cotten CM, Goldstein RF, McDonald SA, Goldberg RN, Salhab WA, Carlo WA, Tyson JE, Finer NN, Walsh MC, Ehrenkranz RA, Laptook AR, Guillet R, Schibler K, Van Meurs KP, Poindexter BB, Stoll BJ, O'Shea TM, Duara S, Das A, Higgins RD, Shankaran S. Apolipoprotein E genotype and outcome in infants with hypoxic-ischemic encephalopathy. Pediatr Res. 2014;75(3):424-430.

O'Shea TM, Joseph RM, Kuban KC, Allred EN, Ware J, Coster T, Fichorova RN, Dammann O, Leviton A. Elevated blood levels of inflammation-related proteins are associated with an attention problem at age 24 mo in extremely preterm infants. Pediatr Res. 2014;75(6):781-787.

Shankaran S, Lin A, Maller-Kesselman J, Zhang H, O'Shea TM, Bada HS, Kaiser JR, Lifton RP, Bauer CR, Ment LR. Maternal race, demography, and health care disparities impact risk for intraventricular hemorrhage in preterm neonates. J Pediatr. 2014;164(5):1005-1011.

Washburn LK, Brosnihan KB, Chappell MC, Diz DI, Gwathmey TM, Nixon PA, Russell GB, Snively BM, O'Shea TM. The renin-angiotensin-aldosterone system in adolescent offspring born prematurely to mothers with preeclampsia. J Renin Angiotensin Aldosterone Syst. 2014;():.

Stevens TP, Finer NN, Carlo WA, Szilagyi PG, Phelps DL, Walsh MC, Gantz MG, Laptook AR, Yoder BA, Faix RG, Newman JE, Das A, Do BT, Schibler K, Rich W, Newman NS, Ehrenkranz RA, Peralta-Carcelen M, Vohr BR, Wilson-Costello DE, Yolton K,. Respiratory outcomes of the surfactant positive pressure and oximetry randomized trial (SUPPORT). J Pediatr. 2014;165(2):240-249.e4.

Yang Q, Ayers K, Chen Y, O'Shea TM. Early enteral fat supplementation improves protein absorption in premature infants with an enterostomy. Neonatology. 2014;106(1):10-16.

Yang Q, Ayers K, Welch CD, O'Shea TM. Randomized controlled trial of early enteral fat supplement and fish oil to promote intestinal adaptation in premature infants with an enterostomy. J Pediatr. 2014;165(2):274-279.e1.

Allred EN, Capone A Jr, Fraioli A, Dammann O, Droste P, Duker J, Gise R, Kuban K, Leviton A, O'Shea TM, Paneth N, Petersen R, Trese M, Stoessel K, Vanderveen D, Wallace DK, Weaver G. Retinopathy of prematurity and brain damage in the very preterm newborn. J AAPOS. 2014;18(3):241-247.

Woods CR, Davis DW, Duncan SD, Myers JA, O'Shea TM. Variation in classification of live birth with newborn period death versus fetal death at the local level may impact reported infant mortality rate. BMC Pediatr. 2014;14():108.

Phadke A, Msall ME, Droste P, Allred EN, O'Shea TM, Kuban K, Dammann O, Leviton A. Impaired visual fixation at the age of 2 years in children born before the twenty-eighth week of gestation. Antecedents and correlates in the multicenter ELGAN study. Pediatr Neurol. 2014;51(1):36-42.

Watkins S, Jonsson-Funk M, Brookhart MA, Rosenberg SA, O'Shea TM, Daniels J. Preschool motor skills following physical and occupational therapy services among non-disabled very low birth weight children. Matern Child Health J. 2014;18(4):821-828.

Holditch-Davis D, White-Traut RC, Levy JA, O'Shea TM, Geraldo V, David RJ. Maternally administered interventions for preterm infants in the NICU: effects on maternal psychological distress and mother-infant relationship. Infant Behav Dev. 2014;37(4):695-710.

Korzeniewski SJ, Soto-Rivera CL, Fichorova RN, Allred EN, Kuban KC, O'Shea TM, Paneth N, Agus M, Dammann O, Leviton A. Are preterm newborns who have relative hyperthyrotropinemia at increased risk of brain damage?. J Pediatr Endocrinol Metab. 2014;27(11-12):1077-1088.

Kuban KC, O'Shea TM, Allred EN, Paneth N, Hirtz D, Fichorova RN, Leviton A. Systemic inflammation and cerebral palsy risk in extremely preterm infants. J Child Neurol. 2014;29(12):1692-1698.

Leviton A, Fichorova RN, O'Shea TM, Kuban K, Paneth N, Dammann O, Allred EN. Two-hit model of brain damage in the very preterm newborn: small for gestational age and postnatal systemic inflammation. Pediatr Res. 2013;73(3):362-370.

Bose CL, Laughon MM, Allred EN, O'Shea TM, Van Marter LJ, Ehrenkranz RA, Fichorova RN, Leviton A. Systemic inflammation associated with mechanical ventilation among extremely preterm infants. Cytokine. 2013;61(1):315-322.

O'Shea TM, Shah B, Allred EN, Fichorova RN, Kuban KC, Dammann O, Leviton A. Inflammation-initiating illnesses, inflammation-related proteins, and cognitive impairment in extremely preterm infants. Brain Behav Immun. 2013;29():104-112.

Morris BH, Tyson JE, Stevenson DK, Oh W, Phelps DL, O'Shea TM, McDavid GE, Van Meurs KP, Vohr BR, Grisby C, Yao Q, Kandefer S, Wallace D, Higgins RD. Efficacy of phototherapy devices and outcomes among extremely low birth weight infants: multi-center observational study. J Perinatol. 2013;33(2):126-133.

Washburn L, Nixon P, Russell G, Snively BM, O'Shea TM. Adiposity in adolescent offspring born prematurely to mothers with preeclampsia. J Pediatr. 2013;162(5):912-917.

Logan JW, Westra SJ, Allred EN, O'Shea TM, Kuban K, Paneth N, Leviton A. Antecedents of perinatal cerebral white matter damage with and without intraventricular hemorrhage in very preterm newborns. Pediatr Neurol. 2013;49(2):88-96.

Yang Q, Ayers K, Chen Y, Helderman J, Welch CD, O'Shea TM. Early enteral fat supplement and fish oil increases fat absorption in the premature infant with an enterostomy. J Pediatr. 2013;163(2):429-434.

Stefanescu BM, Hetu C, Slaughter JC, O'Shea TM, Shetty AK. A pilot study of Biotene OralBalance gel for oral care in mechanically ventilated preterm neonates. Contemp Clin Trials. 2013;35(2):33-39.

Welch C, Helderman J, Williamson E, O'Shea TM. Brain wave maturation and neurodevelopmental outcome in extremely low gestational age neonates. J Perinatol. 2013;33():867-871.

O'Shea TM, Downey LC, Kuban KK. Extreme prematurity and attention deficit: epidemiology and prevention. Front Hum Neurosci. 2013;7():578.

Nixon PA, Washburn LK, O'Shea TM. Antenatal steroid exposure and pulmonary outcomes in adolescents born with very low birth weight. J Perinatol. 2013;33(10):806-810.

Watkins S, Jonsson-Funk M, Brookhart MA, Rosenberg SA, O'Shea TM, Daniels J. An empirical comparison of tree-based methods for propensity score estimation. Health Serv Res. 2013;48(5):1798-1817.

Nageswaran S, Golden SL, Easterling D, O'Shea TM, Hansen WB, Ip EH. Factors associated with collaboration among agencies serving children with complex chronic conditions. Matern Child Health J. 2013;17(9):1533-1540.

Boyd LA, Msall ME, O'Shea TM, Allred EN, Hounshell G, Leviton A. Social-emotional delays at 2 years in extremely low gestational age survivors: correlates of impaired orientation/engagement and emotional regulation. Early Hum Dev. 2013;89(12):925-930.

D'Angio CT, Murray TE, Li L, Heyne RJ, O'Shea TM, Schelonka RL, Shankaran S, Duara S, Goldberg RN, Stoll BJ, Stevenson DK, Vohr BR, Phelps DL, Carlo WA, Pichichero ME, Das A, Higgins RD. Immunogenicity of Haemophilus influenzae type b protein conjugate vaccines in very low birth weight infants [letter]. Pediatr Infect Dis J. 2013;32(12):1400-1402.

Fairchild KD, Schelonka RL, Kaufman DA, Carlo WA, Kattwinkel J, Porcelli PJ, Navarrete CT, Bancalari E, Aschner JL, Walker MW, Perez JA, Palmer C, Lake DE, O'Shea TM, Moorman JR. Septicemia mortality reduction in neonates in a heart rate characteristics monitoring trial. Pediatr Res. 2013;74(5):570-575.

Leviton A, Allred EN, Dammann O, Engelke S, Fichorova RN, Hirtz D, Kuban KC, Ment LR, O'shea TM, Paneth N, Shah B, Schreiber MD. Systemic inflammation, intraventricular hemorrhage, and white matter injury. J Child Neurol. 2013;28(12):1637-1645.

van der Burg JW, Allred EN, McElrath TF, Fichorova RN, Kuban K, O'Shea TM, Dammann O, Leviton A. Is maternal obesity associated with sustained inflammation in extremely low gestational age newborns?. Early Hum Dev. 2013;89(12):949-955.

Phelps DL, Ward RM, Williams RL, Watterberg KL, Laptook AR, Wrage LA, Nolen TL, Fennell TR, Ehrenkranz RA, Poindexter BB, Michael Cotten C, Hallman MK, Frantz ID III, Faix RG, Zaterka-Baxter KM, Das A, Bethany Ball M, Michael O'Shea T,. Pharmacokinetics and safety of a single intravenous dose of myo-inositol in preterm infants of 23-29 wk. Pediatr Res. 2013;74(6):721-729.

Helderman JB, O'Shea TM, Kuban KCK, Allred EN, Hecht JL, Dammann O, Paneth N, McElrath TF, Onderdonk A, Leviton A. Antenatal antecedents of cognitive impairment at 24 months in extremely low gestational age newborns. Pediatrics. 2012;129(3):494-502.

O'Shea TM, Allred EN, Kuban KCK, Hirtz D, Specter B, Durfee S, Paneth N, Leviton A. Intraventricular hemorrhage and developmental outcomes at 24 months of age in extremely preterm infants. J Child Neurol. 2012;27(1):22-29.

O'Shea TM, Allred EN, Kuban KCK,Dammann O, Paneth N, Fichorova R, Hirtz D, Leviton A. Elevated concentrations of inflammation-related proteins in postnatal blood predict severe developmental delay at 2 years of age in extremely preterm infants. J Pediatr. 2012;160(3):395-401.

Leviton A, O'Shea TM, Bednarek FJ, Allred EN, Fichorova RN, Dammann O. Systemic responses of preterm newborns with presumed or documented bacteraemia. Acta Paediatrica. 2012;101(4):355-359.

Nageswaran S, Ip EH, Golden SL, O'Shea TM, Easterling D. Inter-agency collaboration in the care of children with complex chronic conditions. Acad Pediatr. 2012;12(3):189-197.

Kesar TM, Sawaki L, Burdette JH, Cabrera MN, Kolaski K, Smith BP, O'Shea TM, Koman LA, Wittenberg GF. Motor cortical functional geometry in cerebral palsy and its relationship to disability. Clin Neurophysiol. 2012;123(7):1383-1390.

Greenberg RG, Benjamin DK Jr, Gantz MG, Cotten CM, Stoll BJ, Walsh MC, Sanchez PJ, Shankaran S, Das A, Higgins RD, Miller NA, Auten KJ, Walsh TJ, Laptook AR, Carlo WA, Kennedy KA, Finer NN, Duara S, Schibler K, Ehrenkranz RA, Van Meurs KP,. Empiric antifungal therapy and outcomes in extremely low birth weight infants with invasive candidiasis. J Pediatr. 2012;161(2):264-269.

Streimish IG, Ehrenkranz RA, Allred EN, O'Shea TM, Kuban KC, Paneth N, Leviton A. Birth weight- and fetal weight-growth restriction: impact on neurodevelopment. Early Hum Dev. 2012;88(9):765-771.

O'Shea TM, Helderman JB. Diagnosis, epidemiology and prevention of cerebral palsy. US Obstet Gynecol. 2012;7(1):48-52.

Tyler CP, Paneth N, Allred EN, Hirtz D, Kuban K, McElrath T, O'Shea TM, Miller C, Leviton A. Brain damage in preterm newborns and maternal medication: the ELGAN Study. Am J Obstet Gynecol. 2012;207(3):192.e1-9.

Tyson JE, Pedroza C, Langer J, Green C, Morris B, Stevenson D, Van Meurs KP, Oh W, Phelps D, O'Shea M [sic] [O'Shea TM], McDavid GE, Grisby C, Higgins R. Does aggressive phototherapy increase mortality while decreasing profound impairment among the smallest and sickest newborns?. J Perinatol. 2012;32(9):677-684.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Professor, Pediatrics

Clinical Interests

Neonatology, Epidemiology

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