Profile

Clinical Specialties
Acute and Chronic Leukemia, Cancer Cell Biology
Education & Training
  BSUniversity of Hawaii-Manoa1980
  PhDMassachusetts Institute of Technology1987
FellowshipHoward Hughes Medical Institute1993
Research Interests
cancer/oncogenesis , infectious diseases , molecular biology/molecular me
Recent Publications
Murphy AM, Besmer DM, Moerdyk-Schauwecker M, Moestl N, Ornelles DA, Mukherjee P, Grdzelishvili VZ. Vesicular stomatitis virus as an oncolytic agent against pancreatic ductal adenocarcinoma. J Virol. 2012; 86(6):3073-3087.

Honkaniemi E, Talekar G, Huang W, Bogdanovic G, Forestier E, von Doblen U, Engvall M, Ornelles DA, Gooding LR, Gustafsson B. Adenovirus DNA in Guthrie cards from children who develop acute lymphoblastic leukaemia (ALL). Br J Cancer. 2010; 102(5):796-798.

Zhang Y, Huang W, Ornelles DA, Gooding LR. Modeling adenovirus latency in human lymphocyte cell lines. J Virol. 2010; 84(17):8799-8810.

Garnett CT, Talekar G, Mahr JA, Huang W, Zhang Y, Ornelles DA, Gooding LR. Latent species C adenoviruses in human tonsil tissues. J Virol. 2009; 83(6):2417-2428.

Thomas MA, Broughton RS, Goodrum FD, Ornelles DA. E4orf1 limits the oncolytic potential of the E1B-55K deletion mutant adenovirus. J Virol. 2009; 83(6):2406-2416.



Marshall LJ, Moore AC, Ohki M, Kitabayashi I, Patterson D, Ornelles DA. RUNX1 permits E4orf6-directed nuclear localization of the adenovirus E1B-55K protein and associates with centers of viral DNA and RNA synthesis. J Virol. 2008; 82(13):6395-6408.

Henry CJ, Ornelles DA, Mitchell LM, Brzoza-Lewis KL, Hiltbold EM. IL-12 produced by dendritic cells augments CD8+ T cell activation through the production of the chemokines CCL1 and CCL17. J Immunol. 2008; 181(12):8576-8584.

Hart LS, Ornelles D, Koumenis C. The adenoviral E4orf6 protein induces atypical apoptosis in response to DNA damage. J Biol Chem. 2007; 282(9):6061-6067.

Gustafsson B, Huang W, Bogdanovic G, Gauffin F, Nordgren A, Talekar G, Ornelles DA, Gooding LR. Adenovirus DNA is detected at increased frequency in Guthrie cards from children who develop acute lymphoblastic leukaemia. Br J Cancer. 2007; 97(7):992-994.
All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Last Updated 5/17/2012
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