John Owen, M.D., Professor Internal Medicine-Hematology and Oncology

John Owen, M.D.

Professor, Hematology & Oncology
Pathology

Clinical Specialties

Hematology and Blood Coagulation

Contact Information

New Patient Appointments: 336-716-WAKE
Returning Patient Appointments: 336-713-5440
Department: 336-716-4464

Email: jowen@wakehealth.edu

Insurance Accepted »

Education & Training

M.D., Mcmaster University Faculty Medicine-Canada , 1974
B.S.M., Mcmaster University Faculty Medicine-Canada , 1972
Residency, Internal Medicine, University Toronto Med-Canada, 1978
Fellowship,
Fellowship, Columbia U Affil Hosps, 1979

Memberships

Am Federation Of Clinical Rese
Am Gastrointestinal Endoscopy
Am Soc Of Hematology
Aha - Thrombosis Council
Fibrinogen Subcom.Int'Lthrombo
Harvey Society

NPI Number

1366427411

John Owen, M.D.

Professor, Hematology & Oncology Pathology

Contact Information

Academic: 336-716-6777 | Department: 336-716-4464

Email: jowen@wakehealth.edu

Recent Publications

Knovich MA, Farland A, Owen J. Long-term management of acquired thrombotic thrombocytopenic purpura using serial plasma ADAMTS13 measurements. Eur J Haematol. 2012;88(6):518-525.

Shepard GC, Lawson HL, Hawkins GA, Owen J. BsaXI/RFLP analysis of initial or selectively reamplified PCR product is unreliable in detecting the V617F mutation in JAK2. Int J Lab Hematol. 2011;33(3):267-271.

Burke AR, Singh RN, Carroll DL, Owen JD, Kock ND, D'Agostino R Jr, Torti FM, Torti SV. Determinants of the thrombogenic potential of multiwalled carbon nanotubes. Biomaterials. 2011;32(26):5970-5978.

Sane DC, Streer NP, Owen J. Myocardial necrosis in patients with thrombotic thrombocytopenic purpura: pathophysiology and rationale for specific therapy. Eur J Haematol. 2009;82(2):83-92.

Wilhelm AJ, Zabalawi M, Grayson JM, Weant AE, Major AS, Owen J, Bharadwaj M, Walzem R, Thomas MJ, Sorci-Thomas MG, et al. Apolipoprotein A-I and its role in lymphocyte cholesterol homeostasis and autoimmunity. Arterioscler Thromb Vasc Biol. 2009;29(6):843-849.

Wajih N, Owen J, Wallin R. Enhanced functional recombinant factor VII production by HEK 293 cells stably transfected with VKORC1 where the gamma-carboxylase inhibitor calumenin is stably suppressed by shRNA transfection. Thromb Res. 2008;122(3):405-410.

Knovich MA, Lawson HL, Burke MH, McCoy TP, Owen J. Rapid quantitative assay of ADAMTS13 activity on an automated coagulation analyzer: clinical applications and comparison with immunoblot method. Am J Hematol. 2008;83(8):654-656.

Wahla AS, Ruiz J, Noureddine N, Upadhya B, Sane DC, Owen J. Myocardial infarction in thrombotic thrombocytopenic purpura: a single-center experience and literature review. Eur J Haematol. 2008;81(4):311-316.

Sane DC, Owen J. Link between ADAMTS-13 and troponin levels? [letter]. Crit Care Med. 2008;36(10):2959-2960.

Bharadwaj MS, Zabalawi M, Owen JS, Thomas MJ, Zannis VI, Duka A, Sorci-Thomas MG. ApoA-I FIN partially prevents cholesterol deposition and inflammation in skin and lymph nodes of diet-fed LDLr-/-, ApoA-I-/- mice [abstract]. Arterioscler Thromb Vasc Biol. 2007;27(6):e-124.

Huff JD, Keung Y-K, Thakuri M, Beaty MW, Hurd DD, Owen J, Molnar I. Copper deficiency causes reversible myelodysplasia. Am J Hematol. 2007;82(7):625-630.

Zhang L, Lawson HL, Harish VC, Huff JD, Knovich MA, Owen J. Creation of a recombinant peptide substrate for fluorescence resonance energy transfer-based protease assays. Anal Biochem. 2006;358(2):298-300.

Harish VC, Zhang L, Huff JD, Lawson H, Owen J. Isolated antiplasmin deficiency presenting as a spontaneous bleeding disorder in a 63-year-old man. Blood Coagul Fibrinolysis. 2006;17(8):673-675.

Guinto ER, Grafos N, Owen J, Lawson HL, Greenfield RS. A rapid sensitive assay for measuring ADAMTS13 activity in plasma utilizing a novel recombinant Alexa488-vWF86 (Q1599\P1611C) FRET substrate [abstract]. Blood. 2006;108(11 Pt 2):88b.

Wallin R, Wajih N, Owen J. Enhanced synthesis of functional recombinant factors IX and VII by BHK cells engineered to overexpress VKORC1 combined with siRNA silencing of the gamma-carboxylation inhibitor calumenin [abstract]. Blood. 2006;108(11 Pt 1):485a.