Profile

Ann Marie Peiffer, Ph.D.Wake Forest School of Medicine

Ann Marie Peiffer, Ph.D.

Assistant Professor,

Contact Information

Academic: 336-713-6535 | Department: 336-713-3600

Email: apeiffer@wakehealth.edu

Education & Training

  • B.A., Cornell College, 1999
  • M.S., University of Connecticut, 2002
  • Ph.D., University of Connecticut, 2004
Ann Marie Peiffer, Ph.D.

Ann Marie Peiffer, Ph.D.

Assistant Professor, Radiation Oncology
Social Sciences & Health Policy

Research Interests

Auditory Perception; Brain; Radiotherapy; Diffusion Tensor Imaging; Dose Fractionation
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Contact Information

Academic: 336-713-6535 | Department: 336-713-3600

Email: apeiffer@wakehealth.edu

Recent Publications

Donepezil for irradiated brain tumor survivors: a phase III randomized placebo-controlled clinical trial. Rapp SR, Case LD, Peiffer A, Naughton MM [sic] [Naughton MJ], Chan MD, Stieber VW, Moore DF Jr, Falchuk SC, Piephoff JV, Edenfield WJ, Giguere JK, Loghin ME, Shaw EG.. J Clin Oncol. 2015;33(15):1653-1659.

Pathology of fractionated whole-brain irradiation in rhesus monkeys (Macaca mulatta). Hanbury DB, Robbins ME [deceased], Bourland JD, Wheeler KT, Peiffer AM, Mitchell EL, Daunais JB, Deadwyler SA, Cline JM.. Radiat Res. 2015;183(3):367-374.

The peroxisomal proliferator-activated receptor (PPAR) alpha agonist, fenofibrate, prevents fractionated whole-brain irradiation-induced cognitive impairment. Greene-Schloesser D, Payne V, Peiffer AM, Hsu FC, Riddle DR, Zhao W, Chan MD, Metheny-Barlow L, Robbins ME [deceased].. Radiat Res. 2014;181(1):33-44.

Limited margins using modern radiotherapy techniques does not increase marginal failure rate of glioblastoma. Paulsson AK, McMullen KP, Peiffer AM, Hinson WH, Kearns WT, Johnson AJ, Lesser GJ, Ellis TL, Tatter SB, Debinski W, Shaw EG, Chan MD.. Am J Clin Oncol. 2014;37(2):177-181.

A nomogram for predicting distant brain failure in patients treated with gamma knife stereotactic radiosurgery without whole brain radiotherapy. Ayala-Peacock DN, Peiffer AM, Lucas JT, Isom S, Kuremsky JG, Urbanic JJ, Bourland JD, Laxton AW, Tatter SB, Shaw EG, Chan MD.. Neuro Oncol. 2014;16(9):1283-1288.

Taste and smell disturbances after brain irradiation: a dose-volume histogram analysis of a prospective observational study. Leyrer CM, Chan MD, Peiffer AM, Horne E, Harmon M, Carter AF, Hinson WH, Mirlohi S, Duncan SE, Dietrich AM, Lesser GJ.. Pract Radiat Oncol. 2014;4(2):130-135.

Comparison of clinical outcomes and genomic characteristics of single focus and multifocal glioblastoma. Paulsson AK, Holmes JA, Peiffer AM, Miller LD, Liu W, Xu J, Hinson WH, Lesser GJ, Laxton AW, Tatter SB, Debinski W, Chan MD.. J Neurooncol. 2014;119(2):429-435.

Does delay of start of radiation affect clinical outcomes of glioblastoma [abstract]. Randolph DM, Peiffer AM, Paulsson AK, Hinson W, Laxton AW, Tatter SB, Debinski W, Chan MD.. Int J Radiat Oncol Biol Phys. 2014;90(Suppl 1):S295.

Incidence of mild cognitive impairment in irradiated brain tumor survivors [abstract]. Shaw E, McKee N, Case D, Lawrence J, Lesser G, Naughton M, Peiffer A, Loghin M, Giguere J, Stieber V, Rapp S.. Int J Radiat Oncol Biol Phys. 2014;90(Suppl 1):S162-S163.

Genomic predictors of infield and marginal failure for glioblastoma treated with concurrent radiation therapy and temozolomide: a step towards personalized radiation fields? [abstract]. Holmes JA, Paulsson A, Peiffer AM, Miller LD, Xu J, Hinson WH, Lesser GJ, Tatter SB, Debinski W, Chan MD.. Int J Radiat Oncol Biol Phys. 2014;90(Suppl 1):S291-S292.

Radiation-induced cognitive impairment and altered diffusion tensor imaging in a juvenile rat model of cranial radiotherapy. Peiffer AM, Creer RM, Linville C, Olson J, Kulkarni P, Brown JA, Riddle DR, Robbins ME [deceased], Brunso-Bechtold JE [sic] [Brunso-Bechtold JK].. Int J Radiat Biol. 2014;90(9):799-806.

Neuroanatomical target theory as a predictive model for radiation-induced cognitive decline. Peiffer AM, Leyrer CM, Greene-Schloesser DM, Shing E, Kearns WT, Hinson WH, Tatter SB, Ip EH, Rapp SR, Robbins ME [deceased], Shaw EG, Chan MD.. Neurology. 2013;80(8):747-753.

Impact of radiosurgical management of geriatric patients with brain metastases: clinical and quality of life outcomes [abstract]. Randolph D, Peiffer AM, Klepin H, Ayala-Peacock DN, Lester SC, Laxton AW, Tatter SB, Shaw EG, Chan MD.. Int J Radiat Oncol Biol Phys. 2013;87(2 Suppl):S609.

Changes in FDG-PET uptake during a delayed match to samplememory task [abstract]. Linville C, Mintz A, Hampson R, Deadwyler S, Peiffer A.. Neuro Oncol. 2013;15(Suppl 3):95.

Normal tissue complication probability (Ntcp) model of radiation-induced mood disruption [abstract]. Peiffer AM, Burke A, Leyer CM, Shing E, Kearns WT, Hinson WH, Case D, Rapp SR, Shaw EG, Chan MD.. Neuro Oncol. 2013;15(Suppl 3):230.

Phase III randomized, double-blind, placebo-controlled trial of donepezil in irradiated brain tumor survivors [abstract]. Rapp SR, Case D, Peiffer A, Naughton MJ, Stieber VW, Bayer GK, Bilodeau PA, Moore DF, Falchuk SC, Needles BM , Piephoff J, Edenfield WJ, Giguere JK, Erickson N, Loghin ME, Shaw EG.. J Clin Oncol. 2013;31(15 Suppl):2006.

RCR curriculum for graduate students at Wake Forest: still evolving after 5 years [abstract]. Eldridge JC, Lack AK, Peiffer AM, Tytell M.. In: Abstracts of the Quest for Research Excellence 2012 Meeting; 2012 Mar 15-16; Washington (DC). 2012;():82.

Imaging radiation-induced normal tissue injury. Robbins ME, Brunso-Bechtold JK, Peiffer AM, Tsien CI, Bailey JE, Marks LB.. Radiat Res. 2012;177(4):449-466.

The effects of dietary caffeine use and abstention on blood oxygen level-dependent activation and cerebral blood flow. Addicott MA, Peiffer AM, Laurienti PJ.. J Caffeine Res. 2012;2(1):15-22.

Radiation-induced brain injury: a review. Greene-Schloesser D, Robbins ME, Peiffer AM, Shaw EG, Wheeler KT, Chan MD.. Front Oncol. 2012;2():73.

Clinical outcomes of brain metastases treated with Gamma Knife radiosurgery with 3.0T versus 1.5T MRI-based treatment planning: have we finally optimised detection of occult brain metastases?. Loganathan AG, Chan MD, Alphonse N, Peiffer AM, Johnson AJ, McMullen KP, Urbanic JJ, Saconn PA, Bourland JD, Munley MT, Shaw EG, Tatter SB, Ellis TL [deceased].. J Med Imaging Radiat Oncol. 2012;56(5):554-560.

Predictive factors for distant brain failure after primary radiosurgical management of brain metastases [abstract]. Ayala-Peacock D, Peiffer AM, Ellis TL [deceased], Tatter SB, Urbanic JJ, Bourland JD, Shaw EG, Chan MC.. Int J Radiat Oncol Biol Phys. 2012;84(3 Suppl):S296.

Radiation-induced taste and smell toxicity: a dose-volume histogram analysis of a prospective observational study [abstract]. Leyrer M, Chan MD, Peiffer AM, Horne E, Harmon M, Carter AF, Hinson WH, Duncan SE, Dietrich AM, Lesser GJ.. Int J Radiat Oncol Biol Phys. 2012;84(3 Suppl):S302.

Exploring late effects of brain irradiation with a delayed match to sample paradigm [abstract]. Linville C, Hampson R, Deadwyler S, Peiffer A.. Neuro Oncol. 2012;14(Suppl 6):62.

Comparison of clinical outcomes for single focus and multifocal glioblastoma [abstract]. Paulsson A, Peiffer AM, McMullen KP, Hinson WH, Lesser GJ, Ellis TL [deceased], Tatter SB, Shaw EG, Chan MD.. Int J Radiat Oncol Biol Phys. 2012;84(3 Suppl):S274.

Magnetic resonance imaging associates with differences in neurocognitive performance for cancer survivors complaining of cognitive deficits following brain irradiation [abstract]. Peiffer AM, Case D, Shaw EG, Rapp S.. Neuro Oncol. 2012;14(Suppl 6):63.

Ethics in 15 min per week. Peiffer AM, Hugenschmidt CE, Laurienti PJ.. Sci Eng Ethics. 2011;17(2):289-297.

Normal tissue complication modeling of the brain: dose-volume histogram analysis of neurocognitive outcomes of two CCOP trials [abstract]. Leyrer CM, Peiffer AM, Greene-Schloesser DM, Kearns WT, Hinson WH, Tatter SB, Rapp SR, Robbins ME, Shaw EG, Chan MD.. Int J Radiat Oncol Biol Phys. 2011;81(2 Suppl):S184-S185.

Clinical outcomes of brain metastases treated with gamma knife radiosurgery with 3.0 T vs. 1.5 T MRI-based treatment planning [abstract]. Loganathan AG, Chan MD, Alphonse N, Peiffer AM, Johnson A, McMullen KP, Urbanic JJ, Saconn PA, Bourland JD, Munley MT, Shaw EG, Tatter SB, Ellis TL.. Neuro Oncol. 2011;13(Suppl 3):129.

Decreased CTV margin size does not affect patterns of failure for glioblastoma treated with concurrent radiotherapy and temozolomide [abstract]. Paulsson AK, Chan MD, Peiffer AM, Hinson WH, Kearns WT, Lesser GJ, Ellis TL, Tatter SB, Shaw EG, McMullen KP.. Int J Radiat Oncol Biol Phys. 2011;81(2 Suppl):S183.

Normal tissue complication modeling of the brain: dose-volume histogram analysis of neurocognitive outcomes of two CCOP trials [abstract]. Peiffer AM, Leyrer CM, Greene-Schloesser D, Kearns WT, Hinson WH, Tatter SB, Rapp SR, Robbins ME, Shaw EG, Chan MD.. Neuro Oncol. 2011;13(Suppl 3):73.

Multisensory integration and aging. Mozolic JL, Hugenschmidt CE, Peiffer AM, Laurienti PJ. In: Murray MM, Wallace MT, eds. The neural basis of multisensory processes. Boca Raton (FL): CRC Press;2011: 381-395.

Applying capacity analyses to psychophysical evaluation of multisensory interactions. Hugenschmidt CE, Hayasaka S, Peiffer AM, Laurienti PJ.. Inf Fusion. 2010;11(1 Special Issue):12-20.

Developing a problem-based learning (PBL) curriculum for professionalism and scientific integrity training for biomedical graduate students. Jones NL, Peiffer AM, Lambros A, Guthold M, Johnson AD, Tytell M, Ronca AE, Eldridge JC.. J Med Ethics. 2010;36(10):614-619.

Differential effects of radiation and age on diffusion tensor imaging in rats. Peiffer AM, Shi L, Olson J, Brunso-Bechtold JK.. Brain Res. 2010;1351():23-31.

Problem-based learning for professionalism and scientific integrity training of biomedical graduate students: process evaluation. Jones NL, Peiffer AM, Lambros A, Eldridge JC.. J Med Ethics. 2010;36(10):620-626.

Aging and the interaction of sensory cortical function and structure. Peiffer AM, Hugenschmidt CE, Maldjian JA, Casavona R, Srikanth R, Hayasaka S, Burdette JH, Kraft RA, Laurienti PJ.. Hum Brain Mapp. 2009;30(1):228-240.

Methodological considerations for the quantification of self-reported caffeine use. Addicott MA, Yang LL, Peiffer AM, Laurienti PJ.. Psychopharmacology (Berl). 2009;203(3):571-578.

The effect of daily caffeine use on cerebral blood flow: how much caffeine can we tolerate?. Addicott MA, Yang LL, Peiffer AM, Burnett LR, Burdette JH, Chen MY, Hayasaka S, Kraft RA, Maldjian JA, Laurienti PJ.. Hum Brain Mapp. 2009;30(10):3102-3114.

Preservation of crossmodal selective attention in healthy aging. Hugenschmidt CE, Peiffer AM, McCoy TP, Hayasaka S, Laurienti PJ.. Exp Brain Res. 2009;198(2-3):273-285.

Do structural MRI analyses show evidence for cognitive reserve in the healthy aging brain? [abstract]. Peiffer AM, Hugenschmidt CE, Mozolic J, Laurienti PJ.. Gerontologist. 2009;49(Suppl 2):306.

Teaching bioethics and professional conduct through problem-based learning. Jones N, Tytell M, Eldridge JC, Johnson D, Peiffer A, Lambros A. In: Proceedings of the 31st Annual Association for Biology Laboratory Education Conference, vol 31; 2009 June 9-13; Newark (DE). ;2009: 134-161.

Modality-specific selective attention attenuates multisensory integration. Mozolic JL, Hugenschmidt CE, Peiffer AM, Laurienti PJ.. Exp Brain Res. 2008;184(1):39-52.

Relating imaging indices of white matter integrity and volume in healthy older adults. Hugenschmidt CE, Peiffer AM, Kraft RA, Casanova R, Deibler AR, Burdette JH, Maldjian JA, Laurienti PJ.. Cereb Cortex. 2008;18(2):433-442.

Resurrecting Brinley plots for a novel use: meta-analyses of functional brain imaging data in older adults. Peiffer AM, Maldjian JA, Laurienti PJ.. Int J Biomed Imaging. 2008;2008():.

Use of a modified prepulse inhibition paradigm to assess complex auditory discrimination in rodents. Fitch RH, Threlkeld SW, McClure MM, Peiffer AM.. Brain Res Bull. 2008;76(1-2):1-7.

Scientific integrity and professionalism instruction using problem-based learning [abstract]. Peiffer AM, Tytell M, Eldridge JC, Jones NL.. Soc Neurosci Abstr. 2008;2008(Neuroscience Meeting Planner):.

Cross-modal deactivations during modality-specific selective attention. Mozolic JL, Joyner D, Hugenschmidt CE, Peiffer AM, Kraft RA, Maldjian JA, Laurienti PJ.. BMC Neurol. 2008;8():article 35.

Fostering a culture of responsible lab conduct [letter]. Peiffer AM, Laurienti PJ, Hugenschmidt CE.. Science. 2008;322(5905):1186.

Age-related multisensory enhancement in a simple audiovisual detection task. Peiffer AM, Mozolic JL, Hugenschmidt CE, Laurienti PJ.. Neuroreport. 2007;18(10):1077-1081.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Assistant Professor, Radiation Oncology

Ann Marie Peiffer, Ph.D.

Ann Marie Peiffer, Ph.D.

Assistant Professor, Radiation Oncology
Social Sciences & Health Policy

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