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Stephen Peters, M.D., Ph.D.Wake Forest School of Medicine

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Education & Training

  • B.A., Yale University , 1971
  • Ph.D., University of Pennsylvania School of Medicine , 1976
  • M.D., University of Pennsylvania School of Medicine , 1978
  • Internship, Internal Medicine, Johns Hopkins Hosp, 1980
  • Fellowship, Allergy, Johns Hopkins University Schoo, 1982

Memberships

  • Am Assn Of Immunologists
  • Sigma Xi Society
  • Soc for Leukocyte Biology
  • Am Coll Of Physicians
  • Am Federation Of Clinical Rese
  • American Thoracic Society
  • Am Academy Of Allergy & Immuno

NPI Number

  • 1598740656
Stephen Peters, M.D., Ph.D.

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Why No Ratings?

Stephen Peters, M.D., Ph.D.

Associate Director, Center for Genomics and Personalized Medicine Research
Acting Section Chief, Pulmonary, Critical Care, Allergy, and Immunologic Medicine
Professor, Pulmonary, Critical Care, Allergy, and Immunologic Medicine
Center for Genomics and Personalized Medicine Research
Pediatrics
Translational Science Institute

Research Interests

immunology/allergy/inflammatio

Contact Information

Academic: 336-713-7500 | Department: 336-716-2011

Recent Publications

Peters SP, Dykewicz MS. Anticholinergic therapies In: Adkinson NF Jr, Bochner BS, Burks AW, Busse WW, Holgate ST, Lemanske RF, O'Hehir RE, Middleton E Jr, eds. Middleton's allergy: principles and practice. 8th ed. Philadelphia: Elsevier/Saunders;2014: 1552-1566.

Duan QL, Lasky-Su J, Himes BE, Qiu W, Litonjua AA, Damask A, Lazarus R, Klanderman B, Irvin CG, Peters SP, Hanrahan JP, Lima JJ, Martinez FD, Mauger D, Chinchilli VM, Soto-Quiros M, Avila L, Celedon JC, Lange C, Weiss ST, Tantisira KG. A genome-wide association study of bronchodilator response in asthmatics. Pharmacogenomics J. 2014;14(1):41-47.

Ortega VE, Hawkins GA, Moore WC, Hastie AT, Ampleford EJ, Busse WW, Castro M, Chardon D,Erzurum SC, Israel E, Montealegre F, Wezel SE, Peters SP, Meyers DA, Bleecker ER. Effect of rare variants in ADRB2 on risk of severe exacerbations and symptom control during longacting beta agonist treatment in a multiethnic asthma population: a genetic study. Lancet Respir Med. 2014;2(3):204-213.

Park HW, Dahlin A, Tse S, Duan QL, Schuemann B, Martinez FD, Peters SP, Szefler SJ, Lima JJ, Kubo M, Tamari M, Tantisira KG. Genetic predictors associated with improvement of asthma symptoms in response to inhaled corticosteroids. J Allergy Clin Immunol. 2014;133(3):664-669.

Castro M, King TS, Kunselman SJ, Cabana MD, Denlinger L, Holguin F, Kazani SD, Moore WC, Moy J, Sorkness CA, Avila P, Bacharier LB, Bleecker E, Boushey HA, Chmiel J, Fitzpatrick AM, Gentile D, Hundal M, Israel E, Kraft M, Krishnan JA,. Effect of vitamin D3 on asthma treatment failures in adults with symptomatic asthma and lower vitamin D levels: the VIDA randomized clinical trial. JAMA. 2014;311(20):2083-2091.

Wu AC, Himes BE, Lasky-Su J, Litonjua A, Peters SP, Lima J, Kubo M, Tamari M, Nakamura Y, Qiu W, Weiss ST, Tantisira K. Inhaled corticosteroid treatment modulates ZNF432 gene variant's effect on bronchodilator response in asthmatics. J Allergy Clin Immunol. 2014;133(3):723-728.

O'Neal WK, Anderson W, Basta PV, Carretta EE, Doerschuk CM, Barr RG, Bleecker ER, Christenson SA, Curtis JL, Han MK, Hansel NN, Kanner RE, Kleerup EC, Martinez FJ, Miller BE, Peters SP, Rennard SI, Scholand MB, Tal-Singer R,. Comparison of serum, EDTA plasma and P100 plasma for luminex-based biomarker multiplex assays in patients with chronic obstructive pulmonary disease in the SPIROMICS study. J Transl Med. 2014;12():9.

Moore WC, Hastie AT, Li X, Li H, Busse WW, Jarjour NN, Wenzel SE, Peters SP, Meyers DA, Bleecker ER. Sputum neutrophil counts are associated with more severe asthma phenotypes using cluster analysis. J Allergy Clin Immunol. 2014;133(6):1557-1563.

Peters SP. COPD and irreversible airflow obstruction In: Lockey RF, Ledford DK, eds. Asthma: comorbidities, coexisting conditions, and differential diagnosis. Oxford: Oxford University Press;2014: 80-91.

Hawkins G, Robinson MB, Bleecker ER, Meyers DA, Peters SP. RNAseq analysis of gene expression in human airway smooth muscle cells: comparison of classical IL6 signaling and IL6 trans-signaling [abstract]. Am J Respir Crit Care Med. 2014;189():A6384.

Hawkins G, Robinson MB, Moore WC, Hastie AT, Peters SP, Meyers DA, Bleecker ER, Berry M. Serum soluble IL6 receptor levels are elevated in subjects with COPD and are associated with the IL6R coding variation Asp358Ala [abstract]. Am J Respir Crit Care Med. 2014;189():A4288.

Ortega VE, Moore WC, Hawkins G, Ampleford EJ, Busse WW, Castro M, Erzurum SC, Israel E, Wenzel SE, Peters SP, Bleecker ER, Meyers DA. African ancestry is associated with lower baseline lung function, misclassification of disease severity, and healthcare utilization in African Americans with severe asthma [abstract]. Am J Respir Crit Care Med. 2014;189():A6366.

Coverstone AM, Zheng J, Bacharier LB, Fitzpatrick AM, Teague WG, Meyers DA, Peters SP, Li X, Li H, Wenzel SE, Aujla S, Gaston BM, Bleecker ER, Moore WC, Castro M. Predictors of response to bronchodilators in children with severe asthma [abstract]. Am J Respir Crit Care Med. 2014;189():A3839.

Denlinger LC, Manthei DM, Seibold MA, Ahn K, Bleecker E, Boushey HA, Calhoun WJ, Castro M, Chinchili VM, Fahy JV, Hawkins GA, Icitovic N, Israel E, Jarjour NN, King T, Kraft M, Lazarus SC, Lehman E, Martin RJ, Meyers DA,. P2X7-regulated protection from exacerbations and loss of control is independent of asthma maintenance therapy. Am J Respir Crit Care Med. 2013;187(1):28-33.

Holguin F, Comhair SA, Hazen SL, Powers RW, Khatri SS, Bleecker ER, Busse WW, Calhoun WJ, Castro M, Fitzpatrick AM, Gaston B, Israel E, Jarjour NN, Moore WC, Peters SP, Teague WG, Chung KF, Erzurum SC, Wenzel SE. An association between L-arginine/asymmetric dimethyl arginine balance, obesity, and the age of asthma onset phenotype. Am J Respir Crit Care Med. 2013;187(2):153-159.

Duan QL, Du R, Lasky-Su J, Klanderman BJ, Partch AB, Peters SP, Irvin CG, Hanrahan JP, Lima JJ, Blake KV, Liggett SB, Litonjua AA, Tantisira KG. A polymorphism in the thyroid hormone receptor gene is associated with bronchodilator response in asthmatics. Pharmacogenomics J. 2013;13(2):130-136.

Himes BE, Sheppard K, Berndt A, Leme AS, Myers RA, Gignoux CR, Levin AM, Gauderman WJ, Yang JJ, Mathias RA, Romieu I, Torgerson DG, Roth LA, Huntsman S, Eng C, Klanderman B, Ziniti J, Senter-Sylvia J, Szefler SJ, Lemanske RF Jr,. Integration of mouse and human genome-wide association data identifies KCNIP4 as an asthma gene. PLoS One. 2013;8(2):e56179.

Peters SP, Benninger M, Hankin CS, Wang ZH, Bronstone A, Buck P, Lepore MS. Incidence of oral candidiasis among patients with asthma receiving fluticasone propionate/salmeterol dry powder inhaler versus beclomethasone dipropionate hydrofluoroakane: large-scale retrospective claims analysis [abstract]. J Allergy Clin Immunol. 2013;131(2 Suppl):AB2.

Romeo J, Hastie AT, Foster S, Moore W, Peters SP, Bleecker ER, Dykewicz MS. LIGHT is associated with increased cellular infiltrate and levels of TH1 cytokines as well as well as [sic] reduced lung function in human asthma [abstract]. J Allergy Clin Immunol. 2013;131(2 Suppl):AB203.

Mougey EB, Chen C, Tantisira KG, Blake KV, Peters SP, Wise RA, Weiss ST, Lima JJ. Pharmacogenetics of asthma controller treatment. Pharmacogenomics J. 2013;13(3):242-250.

McGeachie MJ, Stahl EA, Himes BE, Pendergrass SA, Lima JJ, Irvin CG, Peters SP, Ritchie MD, Plenge RM, Tantisira KG. Polygenic heritability estimates in pharmacogenetics: focus on asthma and related phenotypes. Pharmacogenet Genomics. 2013;23(6):324-328.

Hastie AT, Moore WC, Li H, Rector BM, Ortega VE, Pascual RM, Peters SP, Meyers DA, Bleecker ER. Biomarker surrogates do not accurately predict sputum eosinophil and neutrophil percentages in asthmatic subjects. J Allergy Clin Immunol. 2013;132(1):72-80.

Li X, Hawkins GA, Ampleford EJ, Moore WC, Li H, Hastie AT, Howard TD, Boushey HA, Busse WW, Calhoun WJ, Castro M, Erzurum SC, Israel E, Lemanske RF Jr, Szefler SJ, Wasserman SI, Wenzel SE, Peters SP, Meyers DA, Bleecker ER. Genome-wide association study identifies TH1 pathway genes associated with lung function in asthmatic patients. J Allergy Clin Immunol. 2013;132(2):313-320.

McGeachie MJ, Wu AC, Chang HH, Lima JJ, Peters SP, Tantisira KG. Predicting inhaled corticosteroid response in asthma with two associated SNPs. Pharmacogenomics J. 2013;13(4):306-311.

Peters SP, Bleecker ER, Kunselman SJ, Icitovic N, Moore WC, Pascual R, Ameredes BT, Boushey HA, Calhoun WJ, Castro M, Cherniack RM, Craig T, Denlinger LC, Engle LL, Dimango EA, Israel E, Kraft M, Lazarus SC, Lemanske RF Jr,. Predictors of response to tiotropium versus salmeterol in asthmatic adults. J Allergy Clin Immunol. 2013;132(5):1068-1074.


Peters SP. When the chief complaint is (or should be) dyspnea in adults. J Allergy Clin Immunol Pract. 2013;1(2):129-136.

Slager RE, Moore WC, Peters SP, Busse WW, Erzurum SC, Wenzel SE, Barnes KC, Mathias RA, Bamshad MJ, Nickerson D, Meyers DA, Bleecker ER. Exome sequencing identifies genes for asthma severity in African-Americans [abstract]. Am J Respir Crit Care Med. 2013;187():A2396.

Hastie AT, Rector B, Moore WC, Li H, Peters SP, Meyers DA, Bleecker ER. Serum and sputum interleukin-33 (IL-33) levels show no association with serum total IgE, positive skin test number, exhaled nitric oxide, or increasing severity of atopic asthma [abstract]. Am J Respir Crit Care Med. 2013;187():A1008.

Ortega VE, Slager RE, Hawkins G, Moore WC, Busse WW, Erzurum SC, Wenzel SE, Barnes KC, Mathias RA, Bamshad MJ, Nickerson D, Peters SP, Meyers DA, Bleecker ER. Exome sequencing of beta2-adrenergic receptor pathway genes reveals rare variants associated with asthma severity In African Americans [abstract]. Am J Respir Crit Care Med. 2013;187():A2129.

Bowers B, Hastie AT, Rector B, Moore WC, Meyers DA, Peters SP, Bleecker ER. Insulin like growth factor binding protein 2 (IGFBP2) is associated with increased sputum cellular infiltrate, increased sputum cytokine levels, and reduced lung function for human subjects with asthma [abstract]. Am J Respir Crit Care Med. 2013;187(Meeting Abstracts):A2397.

Li X, Moore WC, Ampleford EJ, Li H, Hawkins G, Hastie AT, Boushey HA, Busse WW, Castro M, Erzurum SC, Israel E, Lemanske RF, Szefler SJ, Wasserman SI, Wenzel SE, Peters SP, Meyers DA, Bleecker ER. Phenotypic/genetic characteristics of atopic/non-atopic early/late onset asthma [abstract]. Am J Respir Crit Care Med. 2013;187(Meeting Abstracts):A2395.

Ortega VE, Miller SM, Slager RE, Hawkins G, Moore WC, Busse WW, Erzurum SC, Wenzel SE, Barnes KC, Mathias RA, Bamshad MJ, Nickerson D, Peters SP, Bleecker ER, Meyers DA. Whole exome sequencing analysis reveals rare genetic variants associated with response to beta2- adrenergic receptor agonists in African American asthmatics [abstract]. Am J Respir Crit Care Med. 2013;187(Meeting Abstracts):A2122.

Moore WC, Smith R, Krings J, Li X, Li H, Peters SP, Wenzel SE, Meyers DA, Bleecker ER. Elderly subjects with asthma are less responsive to albuterol and ipratropium bromide when compared to younger subjects, but have similar responses to the two drugs [abstract]. Am J Respir Crit Care Med. 2013;187(Meeting Abstracts):A4215.

Hartman JM, Hastie A, Moore WC, Rector B, Peters SP, Bleecker ER, Dykewicz MS. Thioredoxin is positively associated with eosinophils in induced sputum from patients with asthma [abstract]. J Allergy Clin Immunol. 2012;129(2 Suppl):AB209.

Jarjour NN, Erzurum SC, Bleecker ER, Calhoun WJ, Castro M, Comhair SAA, Chung KF, Curran-Everett D, Dweik RA, Fain SB, Fitzpatrick AM, Gaston BM, Israel E, Hastie A, Hoffman EA, Holguin F, Levy BD, Meyers DA, Moore WC, Peters SP,. Severe asthma: lessons learned from the National Heart, Lung, and Blood Institute Severe Asthma Research Program. Am J Respir Crit Care Med. 2012;185(4):356-362.

Tepper RS, Wise RS, Covar R, Irvin CG, Kercsmar CM, Kraft M, Liu MC, O'Connor GT, Peters SP, Sorkness R, Togias A. Asthma outcomes: pulmonary physiology. J Allergy Clin Immunol. 2012;129(3 Suppl):S65-S87.

Hartman JM, Caldwell JW, Pascual RM, Peters SP. Asthma treatment In: Adelman DC, Casale TB, Corren J, eds. Manual of allergy and immunology. 5th ed. Philadelphia: Wolters Kluwer Health/Lippincott Williams & Wilkins;2012: 150-172.

Ortega VE, Hawkins G, Moore WC, Sadeghnejad A, Busse WW, Erzurum SC, Wenzel SE, Peters SP, Meyers DA, Bleecker ER. Characterization of rare variants in the Adam33 gene in asthma cases from two ethnic groups [abstract]. Am J Respir Crit Care Med. 2012;185(Meeting Abstracts):A5609.

Bellinger C, Pascual R, Krings J, Smith R, Burmudez R, Peters SP, Bleecker ER, Moore WC. Similar decrements in FEV1 and FVC in not severe and severe asthma subjects following investigative bronchoscopy [abstract]. Am J Respir Crit Care Med. 2012;185(Meeting Abstracts):A4178.

Slager RE, Moore WC, Peters SP, Busse WW, Erzurum SC, Wenzel SE, Meyers DA, Bleecker ER. Rare TH1 and TH2 pathway genetic variants contribute to severe allergic asthma [abstract]. Am J Respir Crit Care Med. 2012;185(Meeting Abstracts):A2509.

Hawkins G, Li X, Slager R, Moore WC, Peters SP, Bleecker ER, Meyers DA. Exome sequencing of asthma candidate genes in chromosome 2q11-12 and 2q33 [abstract]. Am J Respir Crit Care Med. 2012;185(Meeting Abstracts):A4904.

Moore WC, Hastie AT, Li H, Li X, Busse WW, Wenzel SE, Peters SP, Meyers DA, Bleecker ER. The addition of sputum inflammatory cell counts to the SARP cluster analysis results in similar clinical asthma phenotypes with biologic heterogeneity [abstract]. Am J Respir Crit Care Med. 2012;185(Meeting Abstracts):A3625.

Ortega VE, Hawkins G, Hastie AT, Moore WC, Sadeghnejad A, Busse WW, Erzurum SC, Wenzel SE, Peters SP, Meyers DA, Bleecker ER. Effects of rare beta2-adrenergic receptor gene variants and long-acting beta agonists on healthcare utilization and corticosteroid use in two multi-ethnic asthma populations [abstract]. Am J Respir Crit Care Med. 2012;185(Meeting Abstracts):A2514.

Hastie AT, Moore WC, Li H, Rector BM, Pascual RM, Peters SP, Meyers DA, Bleecker ER. Blood eosinophils, exhaled nitric oxide, and IGE do not accurately predict sputum eosinophils [abstract]. Am J Respir Crit Care Med. 2012;185(Meeting Abstracts):A3926.

Szefler SJ, Chinchilli VM, Israel E, Denlinger LC, Lemanske RF Jr, Calhoun W, Peters SP. Key observations from the NHLBI Asthma Clinical Research Network. Thorax. 2012;67(5):450-455.

Hawkins GA, Robinson MB, Hastie AT, Li X, Li H, Moore WC, Howard TD, Busse WW, Erzurum SC, Wenzel SE, Peters SP, Meyers DA, Bleecker ER. The IL6R variation Asp358 Ala is a potential modifier of lung function in subjects with asthma. J Allergy Clin Immunol. 2012;130(2):510-515.

Slager RE, Otulana BA, Hawkins GA, Yen YP, Peters SP, Wenzel SE, Meyers DA, Bleecker ER. IL-4 receptor polymorphisms predict reduction in asthma exacerbations during response to an anti-IL-4 receptor alpha antagonist. J Allergy Clin Immunol. 2012;130(2):516-522.

Himes BE, Jiang X, Hu R, Wu AC, Lasky-Su JA, Klanderman BJ, Ziniti J, Senter-Sylvia J, Lima JJ, Irvin CG, Peters SP, Meyers DA, Bleecker ER, Kubo M, Tamari M, Nakamura Y, Szefler SJ, Lemanske RF Jr, Zeiger RS, Strunk RC, Martinez FD,. Genome-wide association analysis in asthma subjects identifies SPATS2L as a novel bronchodilator response gene. PLoS Genet. 2012;8(7):e1002824.

Calhoun WJ, Ameredes BT, King TS, Icitovic N, Bleecker ER, Castro M, Cherniack RM, Chinchilli VM, Craig T, Denlinger L, DiMango EA, Engle LL, Fahy JV, Grant JA, Israel E, Jarjour N, Kazani SD, Kraft M, Kunselman SJ, Lazarus SC, Lemanske RF,. Comparison of physician-, biomarker-, and symptom-based strategies for adjustment of inhaled corticosteroid therapy in adults with asthma: the BASALT randomized controlled trial. JAMA. 2012;308(10):987-997.

Lasky-Su J, Himes BE, Raby BA, Klanderman BJ, Sylvia JS, Lange C, Melen E, Martinez FD, Israel E, Gauderman J, Gilliland F, Sleiman P, Hakonarson H, Celedon JC, Soto-Quiros M, Avila L, Lima JJ, Irvin CG, Peters SP, Boushey H, Chinchilli VM, et al. HLA-DQ strikes again: genome-wide association study further confirms HLA-DQ in the diagnosis of asthma among adults. Clin Exp Allergy. 2012;42(12):1724-1733.

Busse WW, Peters SP, Fenton MJ, Mitchell H, Bleecker ER, Castro M, Wenzel S, Erzurum SC, Fitzpatrick AM, Moore WC, et al. Vaccination of patients with mild and severe asthma with a 2009 pandemic H1N1 influenza virus vaccine. J Allergy Clin Immunol. 2011;127(1):130-137.

Peters SP, Icitovic N, Chinchilli VM. Tiotropium step-up therapy in asthma [reply to letter]. N Engl J Med. 2011;364(6):578-579.

Duan QL, Gaume BR, Hawkins GA, Himes BE, Bleecker ER, Klanderman B, Irvin CG, Peters SP, Meyers DA, Hanrahan JP, et al. Regulatory haplotypes in ARG1 are associated with altered bronchodilator response. Am J Respir Crit Care Med. 2011;183(4):449-454.

Fitzpatrick AM, Teague WG, Meyers DA, Peters SP, Li X, Li H, Wenzel SE, Aujla S, Bleecker ER, Moore WC, et al. Heterogeneity of severe asthma in childhood: confirmation by cluster analysis of children in the National Institutes of Health/National Heart, Lung, and Blood Institute Severe Asthma Research Program. J Allergy Clin Immunol. 2011;127(2):382-389.

Huang YJ, Nelson CE, Brodie EL, DeSantis TZ, Baek MS, Liu J, Woyke T, Allgaier M, Bristow J, Peters SP, et al. Airway microbiota and bronchial hyperresponsiveness in patients with suboptimally controlled asthma. J Allergy Clin Immunol. 2011;127(2):372-381.

Liu L, Teague WG, Erzurum S, Fitzpatrick A, Mantri S, Dweik RA, Bleecker ER, Meyers D, Moore W, Peters SP, et al. Determinants of exhaled breath condensate pH in a large population with asthma. Chest. 2011;139(2):328-336.

Ortega VE, Hastie A, Sadeghnejad A, Moore W, Hawkins GA, Peters SP, Busse WW, Calhoun WJ, Meyers DA, Bleecker ER, et al. Rare beta2-adrenergic receptor gene polymorphisms in asthma cases and controls from the Severe Asthma Research Program [abstract]. Am J Respir Crit Care Med. 2011;183(Meeting Abstracts):A1357.


Holguin F, Bleecker ER, Busse WW, Calhoun WJ, Castro M, Erzurum SC, Fitzpatrick AM, Gaston B, Moore WC, Peters SP, et al. Obesity and asthma: an association modified by age of asthma onset. J Allergy Clin Immunol. 2011;127(6):1486-1493.

Li X, Howard TD, Moore WC, Ampleford EJ, Li H, Busse WW, Peters SP, Hawkins GA, Bleecker ER, Meyers DA, et al. Importance of hedgehog interacting protein and other lung function genes in asthma. J Allergy Clin Immunol. 2011;127(6):1457-1465.

Comhair SAA, Gaston BM, Ricci KS, Hammel J, Dweik RA, Meyers D, Ampleford EJ, Bleecker ER, Moore W, Peters SP, et al. Detrimental effects of environmental tobacco smoke in relation to asthma severity. PLoS ONE. 2011;6(5):e18574.

Slager RE, Li H, Moore W, Hawkins G, Peters SP, Busse WW, Chung K, Erzurum SC, Meyers DA, Bleecker ER, et al. Predictive model of severe atopic asthma phenotypes using interleukin 4/13 pathway polymorphisms [abstract]. Am J Respir Crit Care Med. 2011;183():A1332.

Peters SP. Rebuttal from Dr Peters [editorial]. Chest. 2011;139(6):1277-1278.

Moore WC, Evans MD, Bleecker ER, Busse WW, Calhoun WJ, Castro M, Chung KF, Erzurum SC, Pascual RM, Peters SP, et al. Safety of investigative bronchoscopy in the Severe Asthma Research Program. J Allergy Clin Immunol. 2011;128(2):328-336.

Hirota T, Takahashi A, Kubo M, Tsunoda T, Tomita K, Doi S, Fujita K, Miyatake A, Enomoto T, Peters SP, et al. Genome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population. Nat Genet. 2011;43(9):893-896.

Tantisira KG, Lasky-Su J, Harada M, Murphy A, Litonjua AA, Himes BE, Lange C, Lazarus R, Sylvia J, Peters SP, et al. Genomewide association between GLCCI1 and response to glucocorticoid therapy in asthma. N Engl J Med. 2011;365(13):1173-1183.

Pascual RM, Peters SP. Asthma. Med Clin North Am. 2011;95(6):1115-1124.

Drummond MB, Peters SP, Castro M, Holbrook JT, Irvin CG, Smith LJ, Wise RA, Sugar EA. Risk factors for montelukast treatment failure in step-down therapy for controlled asthma. J Asthma. 2011;48(10):1051-1057.

Lang JE, Hossain J, Dixon AE, Shade D, Wise RA, Peters SP, Lima JJ. Does age impact the obese asthma phenotype? Longitudinal asthma control, airway function, and airflow perception among mild persistent asthmatics. Chest. 2011;140(6):1524-1533.

Wechsler ME, Castro M, Lehman E, Chinchilli VM, Sutherland ER, Denlinger L, Lazarus SC, Peters SP, Israel E, Bleecker E, et al. Impact of race on asthma treatment failures in the asthma clinical research network. Am J Respir Crit Care Med. 2011;184(11):1247-1253.

Hawkins GA, Robinson MB, Moore W, Hastie A, Pascual RM, Peters SP, Meyers DA, Bleecker ER. Correlation of serum IL6 with lung function and phenotypic asthma clusters: data from the Severe Asthma Research Program (SARP) [abstract]. Am J Respir Crit Care Med. 2011;183(Meeting Abstracts):A6169.

Hatzis CE, Hastie A, Moore W, Rector B, Sousa A, Knowles R, Peters SP, Meyers DA, Bleecker ER. BAL cell lysate IL1b synthesis and processing correlates with blood eosinophil levels in subjects with asthma [abstract]. Am J Respir Crit Care Med. 2011;183(Meeting Abstracts):A4453.

Holguin F, Moore W, Peters SP, Wenzel SE. Obesity and asthma, an association modified by age of asthma onset [abstract]. Am J Respir Crit Care Med. 2011;183(Meeting Abstracts):A2662.

Li X, Howard TD, Zheng SL, Haselkorn T, Peters SP, Meyers DA, Bleecker ER. Genome-wide association study of asthma identifies RAD50-IL13 and HLA-DR/DQ regions. J Allergy Clin Immunol. 2010;125(2):328-335.

Moore WC, Meyers DA, Wenzel SE, Teague WG, Li H, Li X, D'Agostino R Jr, Castro M, Peters SP, Bleecker ER, et al. Identification of asthma phenotypes using cluster analysis in the Severe Asthma Research Program. Am J Respir Crit Care Med. 2010;181(4):315-323.

Hastie AT, Moore WC, Meyers DA, Vestal PL, Li H, Peters SP, Bleecker ER. Analyses of asthma severity phenotypes and inflammatory proteins in subjects stratified by sputum granulocytes. J Allergy Clin Immunol. 2010;125(5):1028-1036.

Dweik RA, Sorkness RL, Wenzel S, Hammel J, Curran-Everett D, Comhair SAA, Bleecker E, Busse W, Moore W, Peters S, et al. Use of exhaled nitric oxide measurement to identify a reactive, at-risk phenotype among patients with asthma. Am J Respir Crit Care Med. 2010;181(10):1033-1041.

O'Connor RD, Bleecker ER, Long A, Tashkin D, Peters S, Klingman D, Gutierrez B. Subacute lack of asthma control and acute asthma exacerbation history as predictors of subsequent acute asthma exacerbations: evidence from managed care data. J Asthma. 2010;47(4):422-428.

Hawkins GA, Moore WC, Robinson MB, Peters SP, Meyers D, Bleecker ER. IL6R polymorphisms predict measures of lung function in caucasian asthmatics: data from the Severe Asthma Research Program (SARP) [abstract]. Am J Respir Crit Care Med. 2010;181(1 Meeting Abstracts):A1298.

Slager RE, Pascual RM, Moore WC, Hawkins GA, Peters SP, Meyers D, Bleecker ER. GATA3 polymorphisms are predictors of steroid use and atopic asthma in the Severe Asthma Research Program [abstract]. Am J Respir Crit Care Med. 2010;181(1 Meeting Abstracts):A1301.

Ortega VE, Hawkins GA, Montealegre F, Chardon D, Sadeghnejad A, Moore WC, Peters SP, Meyers D, Bleecker ER. Rare beta2 adrenergic receptor gene polymorphisms in asthma cases and controls from different ethnic groups [abstract]. Am J Respir Crit Care Med. 2010;181(1 Meeting Abstracts):A1316.

Peters SP. Special considerations in adults for diagnoses that may coexist with or masquerade as asthma. Ann Allergy Asthma Immunol. 2010;104(6):455-460.

Haselkorn T, Chen H, Miller DP, Fish JE, Peters SP, Weiss ST, Jones CA. Asthma control and activity limitations: insights from the Real-world Evaluation of Asthma Control and Treatment (REACT) study. Ann Allergy Asthma Immunol. 2010;104(6):471-477.

Oppenheimer JJ, Peters SP. Is the maintenance and reliever approach the answer?. Ann Allergy Asthma Immunol. 2010;104(2):112-117.

Li X, Howard TD, Ampleford EJ, Peters SP, Bleecker ER, Meyers DA. Genome-wide association study of asthma severity using proportional odds model identifies TMEM154 [abstract]. Am J Respir Crit Care Med. 2010;181(1 Meeting Abstracts):A3728.

Hastie AT, Albon D, Moore WC, Krings J, Smith RV, Meyers DA, Peters SP, Bleecker ER. Inflammatory protein microarray analysis of sputum from obese subjects with asthma compared with nonobese subjects with asthma [abstract]. Am J Respir Crit Care Med. 2010;181(1 Meeting Abstracts):A6801.

Pascual RM, Moore WC, Peters SP, Li H, Wenzel SE, Meyers DA, Weiss ST, Litonjua AA, Bleecker ER. Serum vitamin D levels are inversely correlated with FEV1 and FVC in asthma [abstract]. Am J Respir Crit Care Med. 2010;181(1 Meeting Abstracts):A6800.

Ortega VE, Peters SP. Beta-2 adrenergic agonists: focus on safety and benefits versus risks. Curr Opin Pharmacol. 2010;10(3):246-253.

Loza MJ, Foster S, Bleecker ER, Peters SP, Penn RB. Asthma and gender impact accumulation of T cell subtypes. Respir Res. 2010;11():art. 103.

Bhatti SK, Hastie AT, Moore WC, Peters SP, Dykewicz MS, Bleecker ER. Increased numbers of macrophages and neutrophils are associated with decreased interleukin-33 (IL-33) levels in asthmatic sputum [abstract]. J Allergy Clin Immunol. 2010;125(2 Suppl 1):AB109.

Hawkins GA, Robinson MB, Moore WC, Hastie AT, Peters SP, Meyers DA, Bleecker ER. Serum levels of soluble IL6R are genetically regulated and correlate with lung function in asthmatics: Severe Asthma Research Program (SARP) [abstract]. J Allergy Clin Immunol. 2010;125(2 Suppl 1):AB357.

Peters SP, Kunselman SJ, Icitovic N, Moore WC, Pascual R, Ameredes BT, Boushey HA, Calhoun WJ, Meyers DA, Bleecker ER, et al. Tiotropium bromide step-up therapy for adults with uncontrolled asthma. N Engl J Med. 2010;363(18):1715-1726.

Sutherland ER, King TS, Icitovic N, Ameredes BT, Bleecker E, Boushey HA, Calhoun WJ, Castro M, cherniack RM, Peters SP, et al. A trial of clarithromycin for the treatment of suboptimally controlled asthma. J Allergy Clin Immunol. 2010;126(4):747-753.

Hastie AT, Moore WC, Meyers DA, Vestal PL, Krings JO, Smith RA, Li H, Peters SP, Bleecker ER. Inflammatory protein analyses of sputum from human subjects with severe or nonsevere asthma [abstract]. Am J Respir Crit Care Med. 2009;179(Online Abstr Issue):A3925.

Breit JS, Hastie AT, Vestal PL, Moore WC, Peters SP, Bleecker ER. Stem cell factor and cKit from asthmatic and normal subjects' epithelial cells and fibroblasts in response to inflammatory mediators [abstract]. Am J Respir Crit Care Med. 2009;179(Online Abstr Issue):A5444.

Pascual RM, Peters SP. Management of chronic asthma: in adults In: Barnes P, Drazen J, Rennard S, Thomson N, eds. Asthma and COPD: basic mechanisms and clinical management. 2nd ed. Boston (MA): Elsevier/Academic Press;2009: 763-774.

Laber DM, Hastie AT, Peters SP, Bleecker ER. Quantitative skin testing in asthmatic subjects enrolled in the Severe Asthma Research Program [abstract]. J Allergy Clin Immunol. 2009;123(3):730.

Hawkins GA, Lazarus R, Smith RS, Tantisira KG, Meyers DA, Peters SP, Weiss ST, Bleecker ER. The glucocorticoid receptor heterocomplex gene STIP1 is associated with improved lung function in asthmatic subjects treated with inhaled corticosteroids. J Allergy Clin Immunol. 2009;123(6):1376-1383.

Jones CA, Bender BG, Haselkorn T, Fish JE, Mink DR, Peters SP, Weiss ST. Predicting asthma control using patient attitudes toward medical care: the REACT Score. Ann Allergy Asthma Immunol. 2009;102(5):385-392.

Peters S. Hydrofluoroalkane mandate in effect January 1, 2009: switch from chlorofluorocarbon- to hydrofluoroalkane-propelled inhalers requires active transition. Clin Cornerstone. 2009;9(3):50-53.

Pascual RM, Peters SP. The irreversible component of persistent asthma. J Allergy Clin Immunol. 2009;124(5):883-890.

Peters SP. Reporting and evaluating genetic association studies [commentary]. Respir Res. 2009;10():art. 109.

Wechsler ME, Kunselman SJ, Chinchilli VM, Bleecker E, Boushey HA, Calhoun WJ, Ameredes BT, Castro M, Craig TJ, Peters SP, et al. Effect of beta2-adrenergic receptor polymorphism on response to longacting beta2 agonist in asthma (LARGE trial): a genotype-stratified, randomised, placebo-controlled, crossover trial. Lancet. 2009;374(9703):1754-1764.

Moore WC, Meyers DA, Li H, D'Agostino R, Peters SP, Bleecker ER. Identification of asthma phenotypes using cluster analysis in the Severe Asthma Research Program [abstract]. Am J Respir Crit Care Med. 2009;179(1 Meeting Abstracts):A2522.

Crowley MB, Moore WC, Smith RV, Meyers DA, Peters SP, Bleeker ER [sic] [Bleecker ER]. The effect of specific air pollutants on FEV1 variability in the Severe Asthma Research Program [abstract]. Am J Respir Crit Care Med. 2009;179(1 Meeting Abstracts):A1291.

Moore WC, Meyers DA, Li H, Peters SP, Bleecker ER. The importance of the 3rd controller medication in the Severe Asthma Research Program [abstract]. Am J Respir Crit Care Med. 2009;179(1 Meeting Abstracts):A2806.

Pascual RM, Slager RE, Li H, Hawkins GA, Peters SP, Moore WC, Meyers DA, Bleecker ER. GATA3 polymorphisms are associated with baseline and maximal post-bronchodilator FEV1 in Severe Asthma Research Program (SARP) asthmatics [abstract]. Am J Respir Crit Care Med. 2009;179(1 Meeting Abstracts):A2449.

Watkins R, Laber D, Peters SP. Chronic obstructive pulmonary disease (COPD) and asthma: similiarites and differences [Web site resource]. World Allergy Organization. 2009;():.

Sorkness RL, Bleecker ER, Busse WW, Calhoun WJ, Castro M, Chung KF, Curran-Everett D, Erzurum SC, Moore WC, Peters SP, et al. Lung function in adults with stable but severe asthma: air trapping and incomplete reversal of obstruction with bronchodilation. J Appl Physiol. 2008;104(2):394-403.

Haselkorn T, Jones CA, Chen H, Rhoa M, Miller DP, Peters SP, Weiss ST. Relationship between asthma control and activity limitation: insights from the REACT study [abstract]. J Allergy Clin Immunol. 2008;121(2 Suppl 1):S160.

Loza MJ, Foster S, Peters SP, Penn RB. Interactive effects of steroids and beta-agonists on accumulation of type 2 T cells. J Allergy Clin Immunol. 2008;121(3):750-755.

Peters SP, Rosenwasser LJ, Vervaet P, O'Brien CD. Cardiac safety of budesonide (BUD)/formoterol (FM) pressurized metered-dose inhaler (pMDI): pooled data from clinical studies of children, adolescents, and adults with asthma [abstract]. J Allergy Clin Immunol. 2008;121(2 Suppl 1):S155.

Rosenwasser LJ, Peters SP, Vervaet P, O'Brien CD. Tolerability of budesonide (BUD)/formoterol (FM) pressurized metered-dose inhaler (pMDI): pooled adverse event (AE) data from clinical studies of children, adolescents, and adults with asthma [abstract]. J Allergy Clin Immunol. 2008;121(2 Suppl 1):S154.

Hawkins GA, Peters SP. Pharmacogenetics of asthma. Methods Mol Biol. 2008;448():359-378.

Pascual RM, Johnson JJ, Peters SP. Asthma: clinical presentation and management In: Fishman AP, Elias JA, Fishman JA, Grippi MA, Senoir RM, Pack AI, eds. Fishman's pulmonary diseases and disorders, vol 1. 4th ed. New York: McGraw Hill Medical;2008: 815-836.

Hite RD, Hastie AT, Seeds MC, Grier BL, Peters SP, Moore WC, Bleecker ER. Surfactant alterations in asthmatics from the Wake Forest Severe Asthma Research Program Center [abstract]. Am J Respir Crit Care Med. 2008;177(Abstr Issue):A100.

Lara A, Khatri SB, Wang Z, Comhair SAA, Xu W, Dweik RA, Bodine M, Bleecker E, Moore W, Peters SP, et al. Alterations of the arginine metabolome in asthma. Am J Respir Crit Care Med. 2008;178(7):673-681.

Litonjua AA, Lasky-Su J, Schneiter K, Tantisira KG, Lazarus R, Klanderman B, Peters SP, Hawkins GA, Meyers DA, Bleecker ER, et al. ARG1 is a novel bronchodilator response gene: screening and replication in four asthma cohorts. Am J Respir Crit Care Med. 2008;178(7):688-694.

Peters SP, Prenner BM, Mezzanotte WS, Martin P, O'Brien CD. Long-term safety and asthma control with budesonide/formoterol versus budesonide pressurized metered-dose inhaler in asthma patients. Allergy Asthma Proc. 2008;29(5):499-516.

Walter MJ, Castro M, Kunselman SJ, Chinchilli VM, Reno M, Ramkumar TP, Avila PC, Boushey HA, Bleecker ER, Peters SP, et al. Predicting worsening asthma control following the common cold. Eur Respir J. 2008;32(6):1548-1554.

Perry CD, Hawkins GA, Hastie AT, Cauthen CG, Diallo A, Li H, Moore WC, Meyers DA, Peters SP, Bleecker ER. Genetic variation in pulmonary and activation-regulated chemokine (PARC/CCL18) in asthma [abstract]. Am J Respir Crit Care Med. 2008;177(Online Abstr Issue):A338.

Cauthen CG, Hastie AT, Wu M, Vestal PL, Moore WC, Krings J, Smith RV, Bleecker ER, Peters SP. Collagen type I fragments associate with cytokines and cell counts in sputum of severe and nonsevere asthmatics [abstract]. Am J Respir Crit Care Med. 2008;177(Online Abstr Issue):A813.

Hastie AT, Vestal PL, Moore WC, Krings J, Smith RV, Peters SP, Bleecker ER. Proteomic microarray analyses of sputum from subjects with asthma compared to subjects with chronic obstructive pulmonary disease (COPD) [abstract]. Am J Respir Crit Care Med. 2008;177(Online Abstr Issue):A960.

Moore WC, Bleecker ER, Curran-Everett D, Erzurum SC, Ameredes BT, Bacharier L, Calhoun WJ, Castro M, Peters SP, Meyers DA, et al. Characterization of the severe asthma phenotype by the National Heart, Lung, and Blood Institute's Severe Asthma Research Program. J Allergy Clin Immunol. 2007;119(2):405-413.

Loza MJ, Peters SP, Foster S, Khan IU, Penn RB. Beta-agonist enhances type 2 T-cell survival and accumulation. J Allergy Clin Immunol. 2007;119(1):235-244.

Moore WC, Peters SP. Update in asthma 2006. Am J Respir Crit Care Med. 2007;175(7):649-654.

Deykin A, Wechsler ME, Boushey HA, Chinchilli VM, Kunselman SJ, Craig TJ, DiMango E, Fahy JV, Kraft M, Peters SP, et al. Combination therapy with a long-acting beta-agonist and a leukotriene antagonist in moderate asthma. Am J Respir Crit Care Med. 2007;175(3):228-234.

Smith RS, Meyers DA, Peters SP, Moore WC, Wenzel SA, Bleecker ER, Hawkins GA. Sequence analysis of HSPA1A and HSPA1B in a multi-ethnic study population. DNA Seq. 2007;18(1):47-53.

Peters SP, Anthonisen N, Castro M, Holbrook JT, Irvin CG, Smith LJ, Wise RA. Randomized comparison of strategies for reducing treatment in mild persistent asthma. N Engl J Med. 2007;356(20):2027-2039.

Peters SP, Jones CA, Haselkorn T, Mink DR, Valacer DJ, Weiss ST. Real-world Evaluation of Asthma Control and Treatment (REACT): findings from a National Web-based survey [abstract]. J Allergy Clin Immunol. 2007;119(1 Suppl):S8.

Surka AE, Hastie AT, Moore WC, Wu M, Krings J, Smith R, Peters SP, Bleecker ER. Corticosteroid effect on brain derived neurotrophic factor (BDNF) in serum and sputum of asthmatics in vivo, and in asthmatic sputum cells and airway fibroblasts in vitro [abstract]. Am J Respir Crit Care Med. 2007;175(Abstr Issue):A56.

O'Brien CD, Peters SP, Prenner BM, Martin P. Long-term safety of budesonide/formoterol pressurized metered-dose inhaler (BUD/FM pMDI) in asthma patients: adverse events and asthma exacerbations [abstract]. Am J Respir Crit Care Med. 2007;175(Abstr Issue):A188.

Prenner BM, Peters SP, Martin P, O'Brien CD. Long-term control of asthma symptoms with budesonide/formoterol pressurized metered-dose inhaler (BUD/FM pMDI) versus BUD pMDI [abstract]. Am J Respir Crit Care Med. 2007;175(Abstr Issue):A190.

O'Brien CD, Peters SP, Prenner BM, Martin P. Resource use with budesonide/formoterol pressurized metered-dose inhaler (BUD/FM pMDI) versus BUD pMDI in asthma patients [abstract]. Am J Respir Crit Care Med. 2007;175(Abstr Issue):A190.

Prenner BM, Peters SP, Martin P, O'Brien CD. Safety pharmacodynamics (PD) of budesonide/formoterol (BUD/FM) pMDI in asthma patients [abstract]. Am J Respir Crit Care Med. 2007;175(Abstr Issue):A190.

Peters SP, Prenner BM, Martin P, O'Brien CD. Long-term effects on lung function of budesonide (BUD) and formoterol (FM) in one pressurized metered-dose inhaler (BUD/FM pMDI) and BUD pMDI in patients with asthma [abstract]. Am J Respir Crit Care Med. 2007;175(Abstr Issue):A192.

Peters SP, Prenner BM, Martin P, O'Brien CD. Bronchodilation with budesonide/formoterol pressuized metered-dose inhaler (BUD/FM pMDI) vs BUD pMDI in asthma patients [abstract]. Am J Respir Crit Care Med. 2007;175(Abstr Issue):A193.

Loza MJ, MacDowell A, Foster S, Wang S, Peters SP, Penn RB. Augmentation of bystander accumulation of human type 2 T cells by beta-agonist is reversed by glucocorticoid treatment [abstract]. Am J Respir Crit Care Med. 2007;175(Abstr Issue):A452.

Pascual RM, Seeds MC, Panettieri RA, Peters SP, Penn RB. Interleukin-1beta (IL-1beta)-mediated microsomal prostaglandin E2(PGE2) synthase (mPGES) induction regulates cyclooxygenase-2 (COX-2) and PGE2 production in human airway smooth muscle (HASM) [abstract]. Am J Respir Crit Care Med. 2007;175(Abstr Issue):A663.

Surka AE, McCallister JW, Hastie AT, Moore WC, Vestel [sic] PL [Vestal PL], Krings J, Smith R, Peters SP, Bleecker ER. Levels of tumor necrosis factor alpha (TNFa) and brain derived neurotrophic factor (BDNF) correlate in sputum but not in serum [abstract]. Am J Respir Crit Care Med. 2007;175(Abstr Issue):A681.

McCallister JW, Hastie AT, Moore WC, Vestal PL, Krings JO, Smith RV, Peters SP, Bleecker ER. Lack of correlation between sputum, exhaled breath condensate and serum levels of tumor necrosis factor-alpha (TNFalpha) in asthma [abstract]. Am J Respir Crit Care Med. 2007;175(Abstr Issue):A684.

Jones CA, Haselkorn T, Valacer DJ, Mink DR, Peters SP, Weiss ST. The influence of patient attitudes on asthma control: insights from the REACT Study [abstract]. Am J Respir Crit Care Med. 2007;175(Abstr Issue):A828.

Smith RS, Li H, Ampleford EA, Peters SP, Moore WC, Meyers DA, Bleecker ER, Hawkins GA. Steroid complex immunophilia FKBP4 is associated with severe asthma [abstract]. Am J Respir Crit Care Med. 2007;175(Abstr Issue):A833.


Lazarus SC, Chinchilli VM, Rollings NJ, Boushey HA, Cherniack R, Craig TJ, Deykin A, DiMango E, Fish JE, Peters SP, et al. Smoking affects response to inhaled corticosteriods or leukotriene receptor antagonists in asthma. Am J Respir Crit Care Med. 2007;175(8):783-790.

Martin RJ, Szefler SJ, King TS, Kraft M, Boushey HA, Chinchilli VM, Craig TJ, DiMango EA, Deykin A, Peters SP, et al. The Predicting Response to Inhaled Corticosteroid Efficacy (PRICE) trial. J Allergy Clin Immunol. 2007;119(1):73-80.

Peters SP, Jones CA, Haselkorn T, Mink DR, Valacer DJ, Weiss ST. Real-world evaluation of asthma control and treatment (REACT): findings from a national Web-based survey. J Allergy Clin Immunol. 2007;119(6):1454-1461.

Peters S, McCallister J, Pascual R. Treatment of moderate persistent asthma [topic reveiw]. UpToDate [online]. 2007;(version 15.2):.

Bleecker E, Tashkin D, Peters S, Long A, O'Connor R, Parasuraman B, Boggs R. A 4-year assessment of severe and non-severe asthma in a real-world setting [abstract]. Value Health. 2007;10(3):A111.

Long A, Bleecker E, O'Connor R, Tashkin D, Peters S, Silkoff P, Parasuraman B, Boggs R. A 4-year assessment of sub-acute lack of asthma control in a real-world setting [abstract]. Value Health. 2007;10(3):A112.

Peters SP, Castro M, Holbrook JT. Reducing asthma treatment [reply to letter]. N Engl J Med. 2007;357(5):505-506.


Macdowell AL, Peters SP. Neutrophils in asthma. Curr Allergy Asthma Rep. 2007;7(6):464-468.

Ortega VE, Hawkins GA, Peters SP, Bleecker ER. Pharmacogenetics of the beta2-adrenergic receptor gene. Immunol Allergy Clin North Am. 2007;27(4):665-684.

Peters SP, Ferguson G, Deniz Y, Reisner C. Uncontrolled asthma: a review of the prevalence, disease burden and options for treatment. Respir Med. 2006;100(7):1139-1151.

Hawkins GA, Tantisira K, Meyers DA, Ampleford EJ, Moore WC, Klanderman B, Liggett SB, Peters SP, Weiss ST, Bleecker ER. Sequence, haplotype and association analysis of ADRbeta2 in a multiethnic asthma case-control study. Am J Respir Crit Care Med. 2006;174(10):1101-1109.

Bukstein D, Kraft M, Liu AH, Peters SP. Asthma end points and outcomes: what have we learned?. J Allergy Clin Immunol. 2006;118(4):S1-S15.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Professor, Pulmonary, Critical Care, Allergy, and Immunologic Medicine

Clinical Specialties

Asthma

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