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James Lester Pirkle Jr, M.D.Wake Forest Baptist Health

Doctor Rating

4.9 out of 5

86 Ratings

James Lester Pirkle Jr, M.D.

Assistant Professor,

Clinical Interests

Peritoneal Dialysis, Hemodialysis

Contact Information

Returning Patient Appointments: 336-716-4650
Department: 336-716-4650

Insurance Accepted »

Education & Training

  • B.S., Georgia Institute of Technology, 1999
  • M.D., University of Alabama-Birmingham, 2003
  • Internship, Medicine, NC Baptist Hospital, 2004
  • Residency, Medicine, NC Baptist Hospital, 2006
  • Fellowship, Nephrology, Vanderbilt Univ Medical School, 2009

Board Certifications

  • American Board of Internal Medicine, Internal Medicine
  • American Board of Internal Medicine, Nephrology

NPI Number

  • 1760411425
James Lester Pirkle Jr, M.D.

Doctor Rating

4.9 out of 5

86 Ratings

James Lester Pirkle Jr, M.D.

Assistant Professor, Nephrology

Contact Information

Academic: 336-716-4650 | Department: 336-716-4650

Recent Publications

Effects of weight-based ultrafiltration rate limits on intradialytic hypotension in hemodialysis. Pirkle JL Jr, Comeau ME, Langefeld CD, Russell GB, Balderston SS, Freedman BI, Burkart JM.. Hemodial Int. 2018;22(2):270-278.

An unexpected case of scurvy in a peritoneal dialysis patient. El Khoury R, Warren M, Ali S, Pirkle JL Jr.. Case Rep Nephrol Dial. 2017;7(3):172-177.

Incidence of hypoglycemia in patients with low GFR treated with insulin and dextrose for hyperkalemia [abstract]. Pierce D, Pirkle J.. Am J Kidney Dis. 2015;65(4):A68.

Incidence of hypoglycemia in patients with low eGFR treated with insulin and dextrose for hyperkalemia. Pierce DA, Russell G, Pirkle JL Jr.. Ann Pharmacother. 2015;49(12):1322-1326.

Hemoglobin stability and patient compliance with darbepoetin alfa in peritoneal dialysis patients after the implementation of the prospective payment system. Pirkle JL Jr, Paoli CJ, Russell G, Petersen J, Burkart J.. Clin Ther. 2014;36(11):1665-1674.

Lactobacillus species can cause a false-positive test for hematuria on dipstick urinalysis [letter]. Pirkle JL, Palavecino EL, Freedman BI.. Am J Med. 2013;126(1):e3-e4.

Hypertension and chronic kidney disease: controversies in pathogenesis and treatment. Pirkle JL, Freedman BI.. Minerva Urol Nefrol. 2013;65(1):37-50.

Anemia management using darbepoetin alfa among peritoneal dialysis (PD) patients at Wake Forest Outpatient Dialysis (WFOPD) [abstract]. Pirkle J, Paoli CJ, Russell G, Petersen J, Burkart J.. Am J Kidney Dis. 2013;61(4):A76.

Immune complex disease with a lupus-like pattern of deposition in an antinuclear antibody-negative patient. Pirkle JL, Freedman BI, Fogo AB.. Am J Kidney Dis. 2013;62(1):159-164.

Cryptococcal meningitis in two patients with idiopathic CD4 lymphocytopenia [abstract]. Stribling WK, Pirkle J, Lichstein PR.. J Gen Intern Med. 2007;22(Suppl 1):240.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Assistant Professor, Nephrology

Clinical Interests

Peritoneal Dialysis, Hemodialysis
James Lester Pirkle Jr, M.D.

James Lester Pirkle Jr, M.D.

Assistant Professor, Nephrology

Doctor Rating

4.9 out of 5

James Lester Pirkle Jr, M.D.86 Ratings


Doctor Ratings

The overall Patient Rating score is the average of responses to the nine questions listed below. The questions are from the Press Ganey Patient Satisfaction Survey. Responses are measured on a 1 to 5 scale, where 1 represents "very poor" and 5 represents "very good."
Press Ganey Patient Satisfaction Survey

CP concern for questions/worries
CP efforts to include in decisions
CP explanations of prob/condition
CP spoke using clear language
Friendliness/courtesy of CP
Likelihood of recommending CP
Patients' confidence in CP
Time CP spent with patient
Wait time at clinic

Patient Comments

Comments are taken from the Care Provider section of the Press Ganey Patient Satisfaction Survey. Comments are posted exactly as they are written. Comments are added weekly. To protect patient privacy and confidentiality, patient names are not included.


excellent condition


love dr pirkle and staff


Dr Pirkle is a knowledgeable, caring, and very helpful provider. I consider myself lucky to be working with him and have been recommending him to other people with renal problems.


Dr. Pirkle is great!!


Dr Pirkle does a great job helping me manage my health. We discuss "game plans" for getting things done and have dialogue as to the best or recommended treatment regimens for me.


Dr. Prikle is very professional and shows concern about his patients. He is easy to talk to.


Excellent in every respect. I am very lucky to have someone of his caliber looking after these aspects of my health. His overall knowledge is very useful to me as I have several issues I am dealing with that are interacting.


excellent, caring physician.


I have lived several places and have had many doctors, but Dr. Pirkle is the best care provider I have ever experienced by far. He is my kidney specialist, but I wished I could see him as my primary care provider as well. He listens to the patient and then give diagnosis/advice. Great attitude and great knowledge. Dr. Pirkle is the best!


Very good man.


You couldn't ask for a better physician than Dr. Pirkle. He is excellent, extremely bright and always focused directly on the concerns of the patient.


*Dr. Pirkle is exemplary in my opinion -


*Dr. Pirkle is one of the best.

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