James Lester Pirkle Jr, M.D.Wake Forest Baptist Health

Doctor Rating

4.8 out of 5

100 Ratings

James Lester Pirkle Jr, M.D.

Assistant Professor,

Clinical Interests

Nephrology, Peritoneal Dialysis, Kidney Disease, Clinical Nephrology

Contact Information

Returning Patient Appointments: 336-716-1486
Department: 336-716-4650

Insurance Accepted »

Education & Training

  • B.S., Georgia Institute of Technology, 1999
  • M.D., University of Alabama-Birmingham, 2003
  • Internship, Medicine, NC Baptist Hospital, 2004
  • Residency, Medicine, NC Baptist Hospital, 2006
  • Fellowship, Nephrology, Vanderbilt Univ Medical School, 2009

Board Certifications

  • American Board of Internal Medicine, Internal Medicine
  • American Board of Internal Medicine, Nephrology

NPI Number

  • 1760411425
James Lester Pirkle Jr, M.D.

Doctor Rating

4.8 out of 5

100 Ratings

James Lester Pirkle Jr, M.D.

Assistant Professor, Nephrology

Contact Information

Academic: 336-716-1486 | Department: 336-716-4650

Recent Publications

Incidence of hypoglycemia in patients with low GFR treated with insulin and dextrose for hyperkalemia [abstract]. Pierce D, Pirkle J.. Am J Kidney Dis. 2015;65(4):A68.

Incidence of hypoglycemia in patients with low eGFR treated with insulin and dextrose for hyperkalemia. Pierce DA, Russell G, Pirkle JL Jr.. Ann Pharmacother. 2015;49(12):1322-1326.

Hemoglobin stability and patient compliance with darbepoetin alfa in peritoneal dialysis patients after the implementation of the prospective payment system. Pirkle JL Jr, Paoli CJ, Russell G, Petersen J, Burkart J.. Clin Ther. 2014;36(11):1665-1674.

Lactobacillus species can cause a false-positive test for hematuria on dipstick urinalysis [letter]. Pirkle JL, Palavecino EL, Freedman BI.. Am J Med. 2013;126(1):e3-e4.

Hypertension and chronic kidney disease: controversies in pathogenesis and treatment. Pirkle JL, Freedman BI.. Minerva Urol Nefrol. 2013;65(1):37-50.

Anemia management using darbepoetin alfa among peritoneal dialysis (PD) patients at Wake Forest Outpatient Dialysis (WFOPD) [abstract]. Pirkle J, Paoli CJ, Russell G, Petersen J, Burkart J.. Am J Kidney Dis. 2013;61(4):A76.

Immune complex disease with a lupus-like pattern of deposition in an antinuclear antibody-negative patient. Pirkle JL, Freedman BI, Fogo AB.. Am J Kidney Dis. 2013;62(1):159-164.

Cryptococcal meningitis in two patients with idiopathic CD4 lymphocytopenia [abstract]. Stribling WK, Pirkle J, Lichstein PR.. J Gen Intern Med. 2007;22(Suppl 1):240.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Assistant Professor, Nephrology

Clinical Interests

Nephrology, Peritoneal Dialysis, Kidney Disease, Clinical Nephrology
James Lester Pirkle Jr, M.D.

James Lester Pirkle Jr, M.D.

Assistant Professor, Nephrology

Doctor Rating

4.8 out of 5

James Lester Pirkle Jr, M.D.100 Ratings


Doctor Ratings

The overall Patient Rating score is the average of responses to the nine questions listed below. The questions are from the Press Ganey Patient Satisfaction Survey. Responses are measured on a 1 to 5 scale, where 1 represents "very poor" and 5 represents "very good."
Press Ganey Patient Satisfaction Survey

CP concern for questions/worries
CP efforts to include in decisions
CP explanations of prob/condition
CP spoke using clear language
Friendliness/courtesy of CP
Likelihood of recommending CP
Patients' confidence in CP
Time CP spent with patient
Wait time at clinic

Patient Comments

Comments are taken from the Care Provider section of the Press Ganey Patient Satisfaction Survey. Comments are posted exactly as they are written. Comments are added weekly. To protect patient privacy and confidentiality, patient names are not included.


Dr Pirkle is the best nephrologist I ever worked with. He is extremely knowledgeable, highly intelligent, and sincerely cares for my health and well-being. Despite his busy schedule, he was able to "squeeze me in" within just a couple of days when I contacted him with an urgent question. I frequently receive his replies after 10pm and before 7am. I have recommended him to several of my friends and will continue to do so. I consider myself extremely lucky to have him as my doctor.


Dr. Pirkle's care and handling of my case was excellent.


Dr Pirkle is exceptionally knowledgeable, compassionate and caring. He goes well beyond and above what I would normally expect from any provider. Over the two years I worked with him, I received multiple communications from him over weekends and in late evenings. Any time I called on him, he was there for me. I can never thank him enough and feel myself very blessed to be his patient.


Pickle is the best.


Always friendly from initial visit. I'm impressed with his vast knowledge.


Excellent doctor -


Very agreeable in effort to provide VA in my health progress.


Very good experience always.


Outstanding provider - apologized for delay.


*Dr. Pirkle is THE BEST-


I really like Dr. Pirkle. He is the best doctor I have ever had. I don't ever feel rushed. He answers all my questions. He is an excellent doctor.


We love Dr Pirkle.!!!!


Great experience with *Dr. Pirkle.


Best Doctor I've ever had in my whole life !!


Exceptional care - attentive and follow up wonderful.


very careing. makes you feel that you and your feelings matter


Physician/doctor is appropriately empathetic and respectful.


Dr Pirkle is the BEST! So professional, pleasant and smart! Amazing asset to Baptist and to his patients!


Literally never let Dr. Pirkle leave. He is the best there is.


One of the most thorough and concerned providers we've ever seen.


*Dr. Pirkle was very sensitive & concerned about Mom & her situation. He was gracious & _____ in explaining this end of life situation -


*Dr. Pirkle is a very smart, helpful, trustworthy great dr.


I am always comfortable with *Dr. Pirkie. He seems genuinely interested in the best care possible for me and if he was not available, I would change my appt. till he was available.


Very passionate Dr.

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