Sean David Reid, Ph.D., Assistant Professor Microbiology and Immunology

Sean David Reid, Ph.D.

Associate Professor, Microbiology & Immunology

Contact Information

Academic: 336-716-9529 | Department: 336-716-2011

Email: sreid@wakehealth.edu

Education & Training

Ph.D., Penn State University , 2000
B.S., Bucknell University , 1994
Fellowship, National Institutes Hlth, 2003

Sean David Reid, Ph.D.

Associate Professor, Microbiology & Immunology

Research Interests

biotechnology, engineering/bioengineering, infectious diseases, medical technology/devices

Contact Information

Academic: 336-716-9529 | Department: 336-716-2011

Email: sreid@wakehealth.edu

Recent Publications

Roberts AL, Connolly KL, Kirse DJ, Evans AK, Poehling KA, Peters TR, Reid SD. Detection of group A Streptococcus in tonsils from pediatric patients reveals high rate of asymptomatic streptococcal carriage. BMC Pediatr. 2012;12():3.

Burch TM, Stanger B, Mizuguchi A, Zurakowski D, Reid SD. Is alcohol-based hand disinfection equivalent to surgical scrub before placing a central venous catheter?. Anesth Analg. 2012;114(3):622-625.

Holder RC, Kirse DJ, Evans AK, Peters TR, Poehling KA, Swords WE, Reid SD. One third of middle ear effusions from children undergoing tympanostomy tube placement had multiple bacterial pathogens. BMC Pediatr. 2012;12():87.

Briggs CM, Holder RC, Reid SD, Parks GD. Activation of human macrophages by bacterial components relieves the restriction on replication of an interferon-inducing parainfluenza virus 5 (PIV5) P/V mutant. Microbes Infect. 2011;13(4):359-368.

Connolly KL, Roberts AL, Holder RC, Reid SD. Dispersal of group A streptococcal biofilms by the cysteine protease SpeB leads to increased disease severity in a murine model. PLoS ONE. 2011;6(4):e18984.

Connolly KL, Braden AK, Holder RC, Reid SD. Srv mediated dispersal of streptococcal biofilms through SpeB is observed in CovRS+ strains. PLoS ONE. 2011;6(12):e28640.

Oliver-Kozup HA, Elliott M, Bachert BA, Martin KH, Reid SD, Schwegler-Berry DE, Green BJ, Lukomski S. The streptococcal collagen-like protein-1 (Scl1) is a significant determinant for biofilm formation by group A Streptococcus. BMC Microbiol. 2011;11():262.

Gwathmey TM, Pendergrass KD, Reid SD, Rose JC, Diz DI, Chappell MC. Angiotensin-(1-7)-angiotensin-converting enzyme 2 attenuates reactive oxygen species formation to angiotensin II within the cell nucleus. Hypertension. 2010;55(1):166-171.

Arimilli S, Sharma SK, Yammani R, Reid SD, Parks GD, Alexander-Miller MA. Pivotal advance: nonfunctional lung effectors exhibit decreased calcium mobilization associated with reduced expression of ORAI1. J Leukoc Biol. 2010;87(6):977-988.

Roberts AL, Connolly KL, Doern CD, Holder RC, Reid SD. Loss of the group A Streptococcus regulator Srv decreases biofilm formation in vivo in an otitis media model of infection. Infect Immun. 2010;78(11):4800-4808.

Parsonage D, Newton GL, Holder RC, Wallace BD, Paige C, Hamilton CJ, Dos Santos PC, Redinbo MR, Reid SD, Claiborne A. Characterization of the N-acetyl-alpha-D-glucosaminyl l-malate synthase and deacetylase functions for bacillithiol biosynthesis in Bacillus anthracis. Biochemistry. 2010;49(38):8398-8414.

Roberts AL, Holder RC, Reid SD. Allelic replacement of the streptococcal cysteine protease SpeB in a delta srv mutant background restores biofilm formation. BMC Res Notes. 2010;3():art. 281.

Doern CD, Roberts AL, Hong W, Nelson J, Lukomski S, Swords WE, Reid SD. Biofilm formation by group A Streptococcus: a role for the streptococcal regulator of virulence (Srv) and streptococcal cysteine protease (SpeB). Microbiology. 2009;155(Pt 1):46-52.

Reid SD, Hong W, Dew KE, Winn DR, Pang B, Watt J, Glover DT, Hollingshead SK, Swords WE. Streptococcus pneumoniae forms surface-attached communities in the middle ear of experimentally infected chinchillas. J Infect Dis. 2009;199(6):786-794.

Gwathmey TM, Pendergrass KD, Shaltout HA, Reid SD, Rose JC, Diz DI, Chappell MC. Steroid-induced fetal programming differentially alters nuclear angiotensin II receptor expression and function [abstract]. Hypertension. 2009;54(4):e42.

Doern CD, Holder RC, Reid SD. Point mutations within the streptococcal regulator of virulence (Srv) alter protein-DNA interactions and Srv function. Microbiology. 2008;154(Pt 7):1998-2007.

Gwathmey TM, Pendergrass KD, Reid SD, Rose JC, Chappell MC. Evidence that the ACE2-angiotensin-(1-7) pathway counterbalances angiotensin II-induced formation of reactive oxygen species in renal nuclei [abstract]. Hypertension. 2008;52(4):e124-e125.

Reid SD, Chaussee MS, Doern CD, Chaussee MA, Montgomery AG, Sturdevant DE, Musser JM. Inactivation of the group A Streptococcus regulator srv results in chromosome wide reduction of transcript levels, and changes in extracellular levels of Sic and SpeB. FEMS Immunol Med Microbiol. 2006;48(2):283-292.