Profile

Education & Training
  BScThames Polytechnic - London1976
  PhDThames Polytechnic - London1980
Memberships
American Association of Advancement of Science
American Association of Cancer Research
Radiation Research Society
Society for Neuroscience
Society for Free Radical Biology and Medicine
Radiological Society of North Amer
American Society of Therapeutic Rad & Onc
Research Interests
arthritis , cancer/oncogenesis , molecular biology/molecular me , neurosciences/behavior , osteoporosis , radiology/imaging
Recent Publications
Robbins ME, Bourland JD, Cline JM, Wheeler KT, Deadwyler SA. A model for assessing cognitive impairment after fractionated whole-brain irradiation in nonhuman primates. Radiat Res. 2011; 175(4):519-525.


Shi L, Olson J, D'Agostino R Jr, Linville C, Nicolle MM, Robbins ME, Wheeler KT, Brunso-Bechtold JK. Aging masks detection of radiation-induced brain injury. Brain Res. 2011; 1385():307-316.


Gilliam-Davis S, Gallagher PE, Payne VS, Kasper SO, Tommasi EN, Westwood BM, Robbins ME, Chappell MC, Diz DI. Long-term systemic angiotensin II type 1 receptor blockade regulates mRNA expression of dorsomedial medulla renin-angiotensin system components. Physiol Genomics. 2011; 43(13):829-835.


Yoshizumi T, Brady SL, Robbins ME, Bourland JD. Specific issues in small animal dosimetry and irradiator calibration. Int J Radiat Biol. 2011; 87(10):1001-1010.


Leyrer CM, Peiffer AM, Greene-Schloesser DM, Kearns WT, Hinson WH, Tatter SB, Rapp SR, Robbins ME, Shaw EG, Chan MD. Normal tissue complication modeling of the brain: dose-volume histogram analysis of neurocognitive outcomes of two CCOP trials [abstract]. Int J Radiat Oncol Biol Phys. 2011; 81(2 Suppl):S184-S185.


Peiffer AM, Leyrer CM, Greene-Schloesser D, Kearns WT, Hinson WH, Tatter SB, Rapp SR, Robbins ME, Shaw EG, Chan MD. Normal tissue complication modeling of the brain: dose-volume histogram analysis of neurocognitive outcomes of two CCOP trials [abstract]. Neuro Oncol. 2011; 13(Suppl 3):73.




Ramanan S, Zhao W, Riddle DR, Robbins ME. Role of PPARs in radiation-induced brain injury. PPAR Res. 2010; 2010():art.234975.


Conner KR, Payne VS, Forbes ME, Robbins ME, Riddle DR. Effects of the AT1 receptor antagonist L-158,809 on microglia and neurogenesis after fractionated whole-brain irradiation. Radiat Res. 2010; 173(1):49-61.


Garcia-Espinosa MA, Shaltout HA, Olson J, Westwood BM, Robbins ME, Link K, Diz DI. Proton magnetic resonance spectroscopy detection of neurotransmitters in dorsomedial medulla correlate with spontaneous baroreceptor reflex function. Hypertension. 2010; 55(2 Pt 2):487-493.


Willey JS, Livingston EW, Robbins ME, Bourland JD, Tirado-Lee L, Smith-Sielicki H, Bateman TA. Risedronate prevents early radiation-induced osteoporosis in mice at multiple skeletal locations. Bone. 2010; 46(1):101-111.


Williams JP, Brown SL, Georges GE, Hauer-Jensen M, Hill RP, Huser AK, Kirsch DG, MacVittie TJ, Mason KA, Robbins ME, et al. Animal models for medical countermeasures to radiation exposure. Radiat Res. 2010; 173(4):557-578.


Robbins ME, Zhao W, Garcia-Espinosa MA Diz DI. Renin-angiotensin system blockers and modulation of radiation-induced brain injury. Curr Drug Targets. 2010; 11(11):1413-1422.


Robbins MEC, Linard C, Panigrahy D. PPARs and anticancer therapies [editorial]. PPAR Res. 2010; 2010():536415.


Creer R, Payne V, Molina D, Shi L, Oppenheim RW, Robbins M, Brunso-Bechtold J. Reduction in hippocampal neuron number in a pediatric model of fractionated whole brain irradiation [abstract]. Soc Neurosci Abstr. 2010; 2010(Neuroscience Meeting Planner):.


Robbins ME, Payne V, Tommasi E, Diz DI, Hsu F-C, Brown WR, Wheeler KT, Olson J, Zhao W. The AT1 receptor antagonist, L-158,809, prevents or ameliorates fractionated whole-brain irradiation-induced cognitive impairment. Int J Radiat Oncol Biol Phys. 2009; 73(2):499-505.




Shi L, Linville MC, Iversen E, Molina DP, Yester J, Wheeler KT, Robbins ME, Brunso-Bechtold JK. Maintenance of white matter integrity in a rat model of radiation-induced cognitive impairment. J Neurol Sci. 2009; 285(1-2):178-184.


Sink KM, Leng X, Williamson J, Kritchevsky SB, Yaffe K, Kuller L, Yasar S, Atkinson H, Robbins M, Goff DC Jr, et al. Angiotensin-converting enzyme inhibitors and cognitive decline in older adults with hypertension: results from the Cardiovascular Health Study. Arch Intern Med. 2009; 169(13):1195-1202.


Ramanan S, Kooshki M, Zhao W, Hsu F-C, Riddle DR, Robbins ME. The PPARalpha agonist fenofibrate preserves hippocampal neurogenesis and inhibits microglial activation after whole-brain irradiation. Int J Radiat Oncol Biol Phys. 2009; 75(3):870-877.


Robbins MEC, Tsien CI, Cao Y, Brunso-Bechtold JK. Molecular radiobiology and imaging biomarkers of postradiotherapy CNS injury [abstract]. In: RSNA 2009 Online Program Abstracts; 2009 Nov 29 - Dec 4; Chicago (IL). 2009; ():.


Schindler MK, Forbes ME, Robbins ME, Riddle DR. Aging-dependent changes in the radiation response of the adult rat brain. Int J Radiat Oncol Biol Phys. 2008; 70(3):826-834.


Spillman WB Jr, Robertson JL, Meissner KE, Jesselli J, Bourland JD, Robbins ME, Shaw EG. Shape factor analysis of progressive rat hepatoma images. J Biomed Opt. 2008; 13(1):art.014030.


Shi L, Molina DP, Robbins ME, Wheeler KT, Brunso-Bechtold JK. Hippocampal neuron number is unchanged 1 year after fractionated whole-brain irradiation at middle age. Int J Radiat Oncol Biol Phys. 2008; 71(2):526-532.


Collins-Underwood JR, Zhao W, Sharpe JG, Robbins ME. NADPH oxidase mediates radiation-induced oxidative stress in rat brain microvascular endothelial cells. Free Radic Biol Med. 2008; 45(6):929-938.


Robbins ME. Mental dysfunction after brain irradiation [reply to letter]. Int J Radiat Oncol Biol Phys. 2008; 72(2):628-629.


Smith-Pearson PS, Kooshki M, Spitz DR, Poole LB, Zhao W, Robbins ME. Decreasing peroxiredoxin II expression decreases glutathione, alters cell cycle distribution, and sensitizes glioma cells to ionizing radiation and H2O2. Free Radic Biol Med. 2008; 45(8):1178-1189.


Gilliam-Davis S, Gallagher PE, Payne VS, Kasper SO, Tommasi EN, Robbins ME, Diz DI. Long-term systemic renin-angiotensin system blockade alters expression of renin-angiotensin system components in dorsomedial medulla of Fischer 344 rats [abstract]. Hypertension. 2008; 52(4):e61.


Ramanan S, Kooshki M, Zhao W, Hsu F-C, Robbins ME. PPARalpha ligands inhibit radiation-induced microglial inflammatory responses by negatively regulating NF-kappaB and AP-1 pathways. Free Radic Biol Med. 2008; 45(12):1695-1704.


Willey JS, Lloyd SAJ, Robbins ME, Bourland JD, Smith-Sielicki H, Bowman LC, Norrdin RW, Bateman TA. Early increase in osteoclast number in mice after whole-body irradiation with 2 Gy X rays. Radiat Res. 2008; 170(3):388-392.


Hua K, Schindler MK, Forbes ME, Robbins ME, Riddle DR. Aging alters the response of oligodendrocyte precursor cells and microglia to whole brain irradiation [abstract]. Soc Neurosci Abstr. 2008; 2008(Neuroscience Meeting Planner):.


Robbins M, Payne V, Diz D, Hsu FC, Zhao WL. Chronic inhibition of the renin-angiotensin system prevents radiation-induced cognitive impairment in the adult male rat [abstract]. Neuro Oncol. 2008; 10(5):851.


Bowman LC, Livingston EW, Willey JS, Robbins ME, Bourland JD, Bateman TA. Radiation-induced bone loss: description of dose, time course, age, strain and sex variables [abstract]. J Bone Miner Res. 2008; 23(Suppl):S335.


Willey JS, Livingston EW, Bowman LC, Robbins ME, Bourland JD, Bateman TA. Risedronate prevents early radiation-induced bone loss at multiple skeletal sites [abstract]. J Bone Miner Res. 2008; 23(Suppl):S20.




Smith PS, Zhao W, Spitz DR, Robbins ME. Inhibiting catalase activity sensitizes 36B10 rat glioma cells to oxidative stress. Free Radic Biol Med. 2007; 42(6):787-797.


Shaw EG, Debinski W, Robbins ME. Central nervous system tumors: overview. In: Gunderson LL, Tepper JE, eds. Clinical radiation oncology. 2nd ed. Philadelphia: Elsevier Churchill Livingstone; 2007: 459-492.


Sink KM, Leng X, Williamson J, Kritchevsky S, Yaffe K, Psaty B, Kuller L, Yasar S, Atkinson H, Robbins M, Goff D. Centrally active ACE inhibitors may slow cognitive decline: the Cardiovascular Health Study [abstract]. J Am Geriatr Soc. 2007; 55(4 Suppl 1):S14.


Brown WR, Blair RM, Moody DM, Thore CR, Ahmed S, Robbins ME, Wheeler KT. Capillary loss precedes the cognitive impairment induced by fractionated whole-brain irradiation: a potential rat model of vascular dementia. J Neurol Sci. 2007; 257(1-2):67-71.




Lally BE, Detterbeck FC, Geiger AM, Thomas CR Jr, Machtay M, Miller AA, Oaks TE, Petty WJ, Robbins ME, Blackstock AW, et al. The risk of death from heart disease in patients with nonsmall cell lung cancer who receive postoperative radiotherapy: analysis of the Surveillance, Epidemiology, and End Results database. Cancer. 2007; 110(4):911-917.


Gilliam-Davis S, Payne VS, Kasper SO, Tommasi EN, Robbins ME, Diz DI. Long-term AT1 receptor blockade improves metabolic function and provides renoprotection in Fischer-344 rats. Am J Physiol Heart Circ Physiol. 2007; 293(3):H1327-33.


Stieber V, Robbins M, deGuzman A, Tatter S, Ekstrand K, McMullen K, Branch C, Shaw E, Bourland JD, Lovato J, Munley M, Ellis T, et al. Determination of a clinical value for the repair half-time (T1/2) of the trigeminal nerve based on outcome data from gamma knife radiosurgery for facial pain. Radiat Res. 2007; 168(2):143-148.


Zhao W, Diz DI, Robbins ME. Oxidative damage pathways in relation to normal tissue injury. Br J Radiol. 2007; 80(Special Issue 1):S23-S31.


Lally BE, Geiger GA, Kridel S, Arcury-Quandt AE, Robbins ME, Kock ND, Wheeler K, Peddi P, Georgakilas A, Koumenis C, et al. Identification and biological evaluation of a novel and potent small molecule radiation sensitizer via an unbiased screen of a chemical library. Cancer Res. 2007; 67(18):8791-8799.


Atwood T, Robbins ME, Zhu J-M. Quantitative in vivo proton MR spectroscopic evaluation of the irradiated rat brain. J Magn Reson Imaging. 2007; 26(6):1590-1595.




Lally BE, Shaw EG, Knisely JPS, Blackstock AW, Robbins MC, Geiger AM. Low grade gliomas: demographic, tumor and treatment factors associated with survival [abstract]. Int J Radiat Oncol Biol Phys. 2007; 69(3 Suppl):S185.


Zhao W, Kridel S, Thorburn A, Kooshki M, Little J, Hebbar S, Robbins M. Fatty acid synthase: a novel target for antiglioma therapy. Br J Cancer. 2006; 95(7):869-878.


Balamucki CJ, Stieber VW, Ellis TL, Tatter SB, DeGuzman AF, McMullen KP, Lovato J, Shaw EG, Ekstrand KE, Bourland JD, Munley MT, Robbins M, Branch C. Does dose rate affect efficacy? The outcomes of 256 gamma knife surgery procedures for trigeminal neuralgia and other types of facial pain as they relate to the half-life of cobalt. J Neurosurg. 2006; 105(5):730-735.


Shi L, Adams MM, Long A, Carter CC, Bennett C, Sonntag WE, Nicolle MM, Robbins M, D'Agostino R Jr, Brunso-Bechtold JK. Spatial learning and memory deficits after whole-brain irradiation are associated with changes in NMDA receptor subunits in the hippocampus. Radiat Res. 2006; 166(6):892-899.


Conner KR, Forbes ME, Gallagher PE, Robbins ME, Riddle DR. Assessing the effects of AT1 receptor blockade on WBI-induced brain damage [abstract]. Soc Neurosci Abstr. 2006; 2006(Abstr Viewer):.


Schindler MK, Robbins ME, Riddle DR. Assessing the effects of aging on radiation-induced brain injury [abstract]. Soc Neurosci Abstr. 2006; 2006(Abstr Viewer):.


Collins-Underwood JR, Zhao W, Kooshki M, Robbins M. Role of NADPH oxidase in radiation-induced oxidative stress and inflammation in brain endothelium [abstract]. Free Radic Res. 2006; 40(Suppl 1):S52.


Smith PS, Zhao W, Robbins M. Knocking down catalase increases sensitivity of gliomas to oxidative stress [abstract]. Free Radic Res. 2006; 40(Suppl 1):S70.


Molina DP, Robbins M, Shi L, Brunso-Bechtold JK. Neuron number remains stable in the hippocampus 12 months after whole brain irradiation [abstract]. Soc Neurosci Abstr. 2006; 2006(Abstr Viewer):.


Robbins ME, Diz DI. Pathogenic role of the renin-angiotensin system in modulating radiation-induced late effects. Int J Radiat Oncol Biol Phys. 2006; 64(1):6-12.
All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Last Updated 2/8/2012
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