Profile

David C. Roberts, Ph.D.

David C. Roberts, Ph.D.

Professor, Physiology & Pharmacology

Contact Information

Academic: 336-716-8597 | Department: 336-716-8597

Email: dcsrobts@wakehealth.edu

Education & Training

  • Ph.D., University British Columbia Med-Canada , 1978
  • M.Sc., University British Columbia Med-Canada , 1976
  • B.Sc., Non-Medical School-Canada , 1973
  • Fellowship, Salk Institute for Biological Studies, 1980

Memberships

  • Society for Neuroscience
  • Canadian Assoc of Neuroscience

NPI Number

  • 1447231857
David C. Roberts, Ph.D.

David C. Roberts, Ph.D.

Professor, Physiology & Pharmacology

Research Interests

neurosciences/behavior, substance abuse

Contact Information

Academic: 336-716-8597 | Department: 336-716-8597

Email: dcsrobts@wakehealth.edu

Recent Publications

Zimmer BA, Dobrin CV, Roberts DC. Examination of behavioral strategies regulating cocaine intake in rats. Psychopharmacology (Berl). 2013;225(4):935-944.

Blume LC, Bass CE, Childers SR, Dalton GD, Roberts DC, Richardson JM, Xiao R, Selley DE, Howlett AC. Striatal CB1 and D2 receptors regulate expression of each other, CRIP1A and delta opioid systems. J Neurochem. 2013;124(6):808-820.

Dobrin CV, Roberts DCS. Cocaine self-administration in rats: discrete trials procedures. Methods Mol Biol. 2012;829():291-302.

Zimmer BA, Roberts DC. Cocaine self-administration in rats: hold-down procedures. Methods Mol Biol. 2012;829():279-290.

Czoty PW, Roberts DCS. Thinking outside the synapse: pharmacokinetic-based medications for cocaine addiction [commentary]. Neuropsychopharmacology. 2012;37(5):1079-1080.

Oleson EB, Roberts DCS. Cocaine self-administration in rats: threshold procedures. Methods Mol Biol. 2012;829():303-319.

Ferris MJ, Calipari ES, Mateo Y, Melchior JR, Roberts DCS, Jones SR. Cocaine self-administration produces pharmacodynamic tolerance: differential effects on the potency of dopamine transporter blockers, releasers, and methylphenidate. Neuropsychopharmacology. 2012;37(7):1708-1716.

Zimmer BA, Oleson EB, Roberts DCS. The motivation to self-administer is increased after a history of spiking brain levels of cocaine. Neuropsychopharmacology. 2012;37(8):1901-1910.

Ferris MJ, Mateo Y, Roberts DCS, Jones SR. Cocaine-insensitive dopamine transporters with intact substrate transport produced by self-administration. Biol Psychiatry. 2011;69(3):201-207.


Espana RA, Melchior JR, Roberts DCS, Jones SR. Hypocretin 1/orexin A in the ventral tegmental area enhances dopamine responses to cocaine and promotes cocaine self-administration. Psychopharmacology (Berl). 2011;214(2):415-426.

Zimmer BA, Dobrin CV, Roberts DCS. Brain-cocaine concentrations determine the dose self-administered by rats on a novel behaviorally dependent dosing schedule. Neuropsychopharmacology. 2011;36(13):2741-2749.

Dobrin CV, Roberts DCS. The anatomy of addiction In: Cavacuiti C, ed. Principles of addiction medicine: the essentials. Philadelphia: Wolters Kluwer Health/Lippincott Williams & Wilkins;2011: 12-16.

Espana RA, Oleson EB, Locke JL, Brookshire BR, Roberts DCS, Jones SR. The hypocretin-orexin system regulates cocaine self-administration via actions on the mesolimbic dopamine system. Eur J Neurosci. 2010;31(2):336-348.

Freeman WM, Lull ME, Patel KM, Brucklacher RM, Morgan D, Roberts DCS, Vrana KE. Gene expression changes in the medial prefrontal cortex and nucleus accumbens following abstinence from cocaine self-administration. BMC Neurosci. 2010;11():article 29.

Bass CE, Jansen HT, Roberts DCS. Free-running rhythms of cocaine self-administration in rats held under constant lighting conditions. Chronobiol Int. 2010;27(3):535-548.

Morgan D, Liu Y, Oleson EB, Roberts DCS. Cocaine self-administration on a hold-down schedule of reinforcement in rats. Psychopharmacology (Berl). 2009;201(4):601-609.

Oleson EB, Talluri S, Childers SR, Smith JE, Roberts DCS, Bonin KD, Budygin EA. Dopamine uptake changes associated with cocaine self-administration. Neuropsychopharmacology. 2009;34(5):1174-1184.

Lull ME, Erwin MS, Morgan D, Roberts DCS, Vrana KE, Freeman WM. Persistent proteomic alterations in the medial prefrontal cortex with abstinence from cocaine self-administration. Proteomics Clin Appl. 2009;3(4):462-472.

Chiodo KA, Roberts DCS. Decreased reinforcing effects of cocaine following 2 weeks of continuous D-amphetamine treatment in rats. Psychopharmacology (Berl). 2009;206(3):447-456.


Smith MA, Ward SJ, Roberts DCS. Lesions of the dorsomedial frontal cortex block sensitization to the positive-reinforcing effects of cocaine. Pharmacol Biochem Behav. 2008;88(3):238-246.


Freeman WM, Patel KM, Brucklacher RM, Lull ME, Erwin M, Morgan D, Roberts DCS, Vrana KE. Persistent alterations in mesolimbic gene expression with abstinence from cocaine self-administration. Neuropsychopharmacology. 2008;33(8):1807-1817.


Fuxe K, Marcellino D, Rivera A, Diaz-Cabiale Z, Filip M, Gago B, Roberts DCS, Langel U, Genedani S, Ferraro L, et al. Receptor-receptor interactions within receptor mosaics. Impact on neuropsychopharmacology. Brain Res Rev. 2008;58(2):415-452.



Marcellino D, Roberts DCS, Navarro G, Filip M, Agnati L, Lluis C, Franco R, Fuxe K. Increase in A2A receptors in the nucleus accumbens after extended cocaine self-administration and its disappearance after cocaine withdrawal. Brain Res. 2007;1143():208-220.

Burkhardt JM, Constantinidis C, Anstrom KK, Roberts DCS, Woodward DJ. Synchronous oscillations and phase reorganization in the basal ganglia during akinesia induced by high-dose haloperidol. Eur J Neurosci. 2007;26(7):1912-1924.

Roberts DCS, Morgan D, Liu Y. How to make a rat addicted to cocaine. Prog Neuropsychopharmacol Biol Psychiatry. 2007;31(8):1614-1624.


Liu Y, Morgan D, Roberts DCS. Cross-sensitization of the reinforcing effects of cocaine and amphetamine in rats. Psychopharmacology (Berl). 2007;195(3):369-375.



Burkhardt JM, Constantinidis C, Anstrom KK, Roberts DC, Woodward DJ. Altered firing patterns in a freely moving rodent haloperidol model of Parkinson's disease [abstract]. Soc Neurosci Abstr. 2006;2006(Abstr Viewer):.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Professor, Physiology & Pharmacology

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