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David C. Roberts, Ph.D.

David C. Roberts, Ph.D.

Professor, Physiology & Pharmacology
Contact Information
Office:
336-716-8597
Fax:
336-716-8501
Email: dcsrobts@wakehealth.edu
Education & Training
  BSc Non-Medical School-Canada 1973
  MSc University British Columbia Med-Canada 1976
  PhD University British Columbia Med-Canada 1978
Fellowship Salk Institute for Biological Studies 1980
Memberships
Society for Neuroscience
Canadian Association of Neuroscience
NPI Number
1447231857
David C. Roberts, Ph.D.

David C. Roberts, Ph.D.

Professor, Physiology & Pharmacology
Contact Information
Office:
336-716-8597
Fax:
336-716-8501
Email: dcsrobts@wakehealth.edu
Research Interests
neurosciences/behavior , substance abuse
Recent Publications
Dobrin CV, Roberts DCS. Cocaine self-administration in rats: discrete trials procedures. Methods Mol Biol. 2012; 829():291-302.

Zimmer BA, Roberts DC. Cocaine self-administration in rats: hold-down procedures. Methods Mol Biol. 2012; 829():279-290.

Czoty PW, Roberts DCS. Thinking outside the synapse: pharmacokinetic-based medications for cocaine addiction [commentary]. Neuropsychopharmacology. 2012; 37(5):1079-1080.

Ferris MJ, Mateo Y, Roberts DCS, Jones SR. Cocaine-insensitive dopamine transporters with intact substrate transport produced by self-administration. Biol Psychiatry. 2011; 69(3):201-207.

Oleson EB, Richardson JM, Roberts DCS. A novel IV cocaine self-administration procedure in rats: differential effects of dopamine, serotonin, and GABA drug pre-treatments on cocaine consumption and maximal price paid. Psychopharmacology (Berl). 2011; 214(2):567-577.

Espana RA, Melchior JR, Roberts DCS, Jones SR. Hypocretin 1/orexin A in the ventral tegmental area enhances dopamine responses to cocaine and promotes cocaine self-administration. Psychopharmacology (Berl). 2011; 214(2):415-426.

Zimmer BA, Dobrin CV, Roberts DCS. Brain-cocaine concentrations determine the dose self-administered by rats on a novel behaviorally dependent dosing schedule. Neuropsychopharmacology. 2011; 36(13):2741-2749.

Espana RA, Oleson EB, Locke JL, Brookshire BR, Roberts DCS, Jones SR. The hypocretin-orexin system regulates cocaine self-administration via actions on the mesolimbic dopamine system. Eur J Neurosci. 2010; 31(2):336-348.

Freeman WM, Lull ME, Patel KM, Brucklacher RM, Morgan D, Roberts DCS, Vrana KE. Gene expression changes in the medial prefrontal cortex and nucleus accumbens following abstinence from cocaine self-administration. BMC Neurosci. 2010; 11():article 29.

Bass CE, Jansen HT, Roberts DCS. Free-running rhythms of cocaine self-administration in rats held under constant lighting conditions. Chronobiol Int. 2010; 27(3):535-548.

Morgan D, Liu Y, Oleson EB, Roberts DCS. Cocaine self-administration on a hold-down schedule of reinforcement in rats. Psychopharmacology (Berl). 2009; 201(4):601-609.

Oleson EB, Talluri S, Childers SR, Smith JE, Roberts DCS, Bonin KD, Budygin EA. Dopamine uptake changes associated with cocaine self-administration. Neuropsychopharmacology. 2009; 34(5):1174-1184.

Lull ME, Erwin MS, Morgan D, Roberts DCS, Vrana KE, Freeman WM. Persistent proteomic alterations in the medial prefrontal cortex with abstinence from cocaine self-administration. Proteomics Clin Appl. 2009; 3(4):462-472.

Chiodo KA, Roberts DCS. Decreased reinforcing effects of cocaine following 2 weeks of continuous D-amphetamine treatment in rats. Psychopharmacology (Berl). 2009; 206(3):447-456.

Lack CM, Jones SR, Roberts DCS. Increased breakpoints on a progressive ratio schedule reinforced by IV cocaine are associated with reduced locomotor activation and reduced dopamine efflux in nucleus accumbens shell in rats. Psychopharmacology (Berl). 2008; 195(4):517-525.

Smith MA, Ward SJ, Roberts DCS. Lesions of the dorsomedial frontal cortex block sensitization to the positive-reinforcing effects of cocaine. Pharmacol Biochem Behav. 2008; 88(3):238-246.

Espana RA, Roberts DCS, Jones SR. Short-acting cocaine and long-acting GBR-12909 both elicit rapid dopamine uptake inhibition following intravenous delivery. Neuroscience. 2008; 155(1):250-257.

Freeman WM, Patel KM, Brucklacher RM, Lull ME, Erwin M, Morgan D, Roberts DCS, Vrana KE. Persistent alterations in mesolimbic gene expression with abstinence from cocaine self-administration. Neuropsychopharmacology. 2008; 33(8):1807-1817.

Chiodo KA, Lack CM, Roberts DCS. Cocaine self-administration reinforced on a progressive ratio schedule decreases with continuous D-amphetamine treatment in rats. Psychopharmacology (Berl). 2008; 200(4):465-473.

Fuxe K, Marcellino D, Rivera A, Diaz-Cabiale Z, Filip M, Gago B, Roberts DCS, Langel U, Genedani S, Ferraro L, et al. Receptor-receptor interactions within receptor mosaics. Impact on neuropsychopharmacology. Brain Res Rev. 2008; 58(2):415-452.

Oleson EB, Roberts DCS. Behavioral economic assessment of price and cocaine consumption following self-administration histories that produce escalation of either final ratios or intake. Neuropsychopharmacology. 2008; 34(3):796-804.

Anstrom KK, Schallert T, Woodlee MT, Shattuck A, Roberts DCS. Repetitive vibrissae-elicited forelimb placing before and immediately after unilateral 6-hydroxydopamine improves outcome in a model of Parkinson's disease. Behav Brain Res. 2007; 179(2):183-191.

Marcellino D, Roberts DCS, Navarro G, Filip M, Agnati L, Lluis C, Franco R, Fuxe K. Increase in A2A receptors in the nucleus accumbens after extended cocaine self-administration and its disappearance after cocaine withdrawal. Brain Res. 2007; 1143():208-220.

Burkhardt JM, Constantinidis C, Anstrom KK, Roberts DCS, Woodward DJ. Synchronous oscillations and phase reorganization in the basal ganglia during akinesia induced by high-dose haloperidol. Eur J Neurosci. 2007; 26(7):1912-1924.

Roberts DCS, Morgan D, Liu Y. How to make a rat addicted to cocaine. Prog Neuropsychopharmacol Biol Psychiatry. 2007; 31(8):1614-1624.

Ward SJ, Roberts DCS. Microinjection of the delta-opioid receptor selective antagonist naltrindole 5'-isothiocyanate site specifically affects cocaine self-administration in rats responding under a progressive ratio schedule of reinforcement. Behav Brain Res. 2007; 182(1):140-144.

Liu Y, Morgan D, Roberts DCS. Cross-sensitization of the reinforcing effects of cocaine and amphetamine in rats. Psychopharmacology (Berl). 2007; 195(3):369-375.

McCracken CB, Roberts DCS. A single evoked afterdischarge produces rapid time-dependent changes in connexin36 protein expression in adult rat dorsal hippocampus. Neurosci Lett. 2006; 405(1-2):84-88.

Wojnicki FHE, Roberts DCS, Corwin RLW. Effects of baclofen on operant performance for food pellets and vegetable shortening after a history of binge-type behavior in non-food deprived rats. Pharmacol Biochem Behav. 2006; 84(2):197-206.

Burkhardt JM, Constantinidis C, Anstrom KK, Roberts DC, Woodward DJ. Altered firing patterns in a freely moving rodent haloperidol model of Parkinson's disease [abstract]. Soc Neurosci Abstr. 2006; 2006(Abstr Viewer):.
All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

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Last Updated 4/9/2012
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