Profile

Mac Breven Robinson, Ph.D.Wake Forest School of Medicine

Mac Breven Robinson, Ph.D.

Instructor,

Contact Information

Academic: 336-716-0541 | Department: 336-716-4368

Email: macrobin@wakehealth.edu

Education & Training

  • Master of Science, Wake Forest University, 2012
  • Ph.D., Wake Forest University, 2013
  • Bachelor of Science, James Madison University, 2014
Mac Breven Robinson, Ph.D.

Mac Breven Robinson, Ph.D.

Instructor, Neurobiology & Anatomy

Research Interests

Motor Neurons; HSP70 Heat-Shock Proteins; Cell Survival; HSC70 Heat-Shock Proteins; Oxidative Stress
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Contact Information

Academic: 336-716-0541 | Department: 336-716-4368

Email: macrobin@wakehealth.edu

Recent Publications

Extracellular vesicles as modulators of cell-to-cell communication in the healthy and diseased brain [article reviews]. Tytell M, Robinson M.. Faculty 1000 Medicine. 2015;February():718540963.

The discovery of Hsp70 domain with cell-penetrating activity [article reviews]. Tytell M, Robinson M.. Faculty 1000 Medicine. 2015;May():725450399.

Ionizing radiation injury of the skin: histologic and metabolomic evaluation in the pig as a model for testing the potential benefits of topical treatments for cutaneous radiation injury [abstract]. Tytell M, Robinson MB, Dorand JE, Gabard AR, Hurt JK, Anderson AM, Bourland JD, Liu J, Burnett LR.. F1000Research. 2015;4():197.

IL-6 trans-signaling increases expression of airways disease genes in airway smooth muscle. Robinson MB, Deshpande DA, Chou J, Cui W, Smith S, Langefeld C, Hastie AT, Bleecker ER, Hawkins GA.. Am J Physiol Lung Cell Mol Physiol. 2015;309(2):L129-L138.

Inner ear supporting cells protect hair cells by secreting HSP70 [article reviews]. Tytell M, Robinson M.. Faculty 1000 Medicine. 2014;May():718046178.

Suppression of UV-induced wrinkle formation by induction of HSP70 expression in mice [article reviews]. Tytell M, Robinson M.. Faculty 1000 Medicine. 2014;March():718299658.

RNAseq analysis of gene expression in human airway smooth muscle cells: comparison of classical IL6 signaling and IL6 trans-signaling [abstract]. Hawkins G, Robinson MB, Bleecker ER, Meyers DA, Peters SP.. Am J Respir Crit Care Med. 2014;189():A6384.

Serum soluble IL6 receptor levels are elevated in subjects with COPD and are associated with the IL6R coding variation Asp358Ala [abstract]. Hawkins G, Robinson MB, Moore WC, Hastie AT, Peters SP, Meyers DA, Bleecker ER, Berry M.. Am J Respir Crit Care Med. 2014;189():A4288.

Moderate alcohol induces stress proteins HSF1 and hsp70 and inhibits proinflammatory cytokines resulting in endotoxin tolerance [article reviews]. Tytell M, Robinson M.. Faculty 1000 Medicine. 2014;August():718490577.

Reversal of cognitive decline: a novel therapeutic program [article reviews]. Tytell M, Robinson M.. Faculty 1000 Medicine. 2014;November():725000619.

Ionizing radiation injury of the skin: histologic and metabolomic evaluation in the pig as a model for testing the potential benefits of topical treatments for cutaneous radiation injury [abstract]. Tytell M, Robinson MB, Dorand JE, Gabard AR, Hurt JK, Anderson AM, Bourland JD, Burnett LR.. Mol Biol Cell. 2014;25(Meeting Abstract):P632.

Ionizing radiation injury of the skin: histologic and metabolomic evaluation in the pig [abstract]. Tytell M, Robinson MB, Dorand JE, Gabard AR, Hurt JK, Anderson AM, Bourland JD, Burnett L.. In: Abstracts of the Assessment, Mitigation & Treatment of Radiation Injury Workshop; 2014 Oct. 8-10; Baltimore (MD). 2014;():12.

Radiation therapy induces circulating serum Hsp72 in patients with prostate cancer [article reviews]. Tytell M, Robinson M.. Faculty 1000 Medicine. 2013;March():717982010.

The membrane-associated transient receptor potential vanilloid channel is the central heat shock receptor controlling the cellular heat shock response in epithelial cells [article reviews]. Tytell M, Robinson M.. Faculty 1000 Medicine. 2013;May():718008464.

Loss of the inducible Hsp70 delays the inflammatory response to skeletal muscle injury and severely impairs muscle regeneration [article reviews]. Tytell M, Robinson M.. Faculty 1000 Medicine. 2013;July():718022523.

Muscle fiber-type regulation of maintenance of neuromuscular junction innervation [abstract]. Milligan C, Strupe J, Mansfield C, Robinson M, Oppenheim R, Rodrigues AZ, Kudo R.. Soc Neurosci Abstr. 2013;():243.19.

Neuroprotective effects of geranylgeranylacetone in experimental traumatic brain injury [article reviews]. Tytell M, Robinson M.. Faculty 1000 Medicine. 2013;September():718074955.

Molecular chaperone mediated late-stage neuroprotection in the SOD1(G93A) mouse model of amyotrophic lateral sclerosis [article reviews]. Tytell M, Robinson M.. Faculty 1000 Medicine. 2013;November():718105400.

Motoneuron programmed cell death in response to proBDNF. Taylor AR, Gifondorwa DJ, Robinson MB, Strupe JL, Prevette D, Johnson JE, Hempstead B, Oppenheim RW, Milligan CE.. Dev Neurobiol. 2012;72(5):699-712.

The IL6R variation Asp358 Ala is a potential modifier of lung function in subjects with asthma. Hawkins GA, Robinson MB, Hastie AT, Li X, Li H, Moore WC, Howard TD, Busse WW, Erzurum SC, Wenzel SE, Peters SP, Meyers DA, Bleecker ER.. J Allergy Clin Immunol. 2012;130(2):510-515.

Administration of recombinant heat shock protein 70 delays peripheral muscle denervation in the SOD1G93A mouse model of amyotrophic lateral sclerosis. Gifondorwa DJ, Jimenz-Moreno R, Hayes CD, Rouhani H, Robinson MB, Strupe JL, Caress J, Milligan C.. Neurol Res Int. 2012;2012():170426.

Mechanisms of the motoneuron stress response and its relevance in neurodegeneration. Robinson MB, Gifondorwa DJ, Milligan C. In: McNeill AS, ed. Neurodegeneration: theory, disorders, and treatments. New York: Nova Biomedical;2011: 45-62.

Correlation of serum IL6 with lung function and phenotypic asthma clusters: data from the Severe Asthma Research Program (SARP) [abstract]. Hawkins GA, Robinson MB, Moore W, Hastie A, Pascual RM, Peters SP, Meyers DA, Bleecker ER.. Am J Respir Crit Care Med. 2011;183(Meeting Abstracts):A6169.

IL6 signaling in human airway smooth muscle (hasm): distinct signaling effected by the soluble IL6 receptor and functional consequences [abstract]. Robinson MB, Deshpande DA, Pascual RM, Panettieri RA, Penn R, Meyers DA, Bleecker ER, Hawkins GA.. Am J Respir Crit Care Med. 2011;183():A2074.

IL6R polymorphisms predict measures of lung function in caucasian asthmatics: data from the Severe Asthma Research Program (SARP) [abstract]. Hawkins GA, Moore WC, Robinson MB, Peters SP, Meyers D, Bleecker ER.. Am J Respir Crit Care Med. 2010;181(1 Meeting Abstracts):A1298.

Serum levels of soluble IL6R are genetically regulated and correlate with lung function in asthmatics: Severe Asthma Research Program (SARP) [abstract]. Hawkins GA, Robinson MB, Moore WC, Hastie AT, Peters SP, Meyers DA, Bleecker ER.. J Allergy Clin Immunol. 2010;125(2 Suppl 1):AB357.

Exogenous Hsc70, but not thermal preconditioning, confers protection to motoneurons subjected to oxidative stress. Robinson MB, Taylor AR, Gifondorwa DJ, Tytell M, Milligan CE.. Dev Neurobiol. 2008;68(1):1-17.

Release of heat shock proteins and their effects when in the extracellular space in the nervous system. Tytell M, Robinson MB, Milligan CE. In: Asea AAA, Brown IR, eds. Heat shock proteins and the brain: implications for neurodegenerative diseases and neuroprotection. Dordrecht (Netherlands): Springer;2008: 257-272.

Astrocyte and muscle-derived secreted factors differentially regulate motoneuron survival. Taylor AR, Gifondorwa DJ, Newbern JM, Robinson MB, Strupe JL, Prevette D, Oppenheim RW, Milligan CE.. J Neurosci. 2007;27(3):634-644.

In vitro methods to prepare astrocyte and motoneuron cultures for the investigation of potential in vivo interactions. Taylor AR, Robinson MB, Milligan CE.. Nat Protoc. 2007;2(6):1499-1507.

c-Jun N-terminal kinase signaling regulates events associated with both health and degeneration in motoneurons. Newbern J, Taylor A, Robinson M, Lively MO, Milligan CE.. Neuroscience. 2007;147(3):680-692.

Regulation of heat shock protein 70 release in astrocytes: role of signaling kinases. Taylor AR, Robinson MB, Gifondorwa DJ, Tytell M, Milligan CE.. Dev Neurobiol. 2007;67(13):1815-1829.

Exogenous delivery of heat shock protein 70 increases lifespan in a mouse model of amyotrophic lateral sclerosis. Gifondorwa DJ, Robinson MB, Hayes CD, Taylor AR, Prevette DM, Oppenheim RW, Caress J, Milligan CE.. J Neurosci. 2007;27(48):13173-80.

Astrocyte- and muscle-secreated factors differentially regulate motoneuron survival [abstract]. Taylor AR, Robinson MB, Prevette D, Gifondorwa D, Newbern JM, Strupe J, Oppenheim RW, Milligan CE.. Soc Neurosci Abstr. 2006;2006(Abstr Viewer):.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Mac Breven Robinson, Ph.D.

Mac Breven Robinson, Ph.D.

Instructor, Neurobiology & Anatomy

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