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Jimmy Ruiz, M.D.Wake Forest School of Medicine

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Jimmy Ruiz, M.D.

Assistant Professor,

Clinical Interests

Lung Cancer, Thoracic Cancer

Contact Information

Returning Patient Appointments: 336-713-5440
Department: 336-716-4464

Insurance Accepted »

Additional Languages


Education & Training

  • M.D., Southern Illinois University-Carbondale, 2004
  • Residency, Internal Medicine, NC Baptist Hospital, 2005
  • Internship, Internal Medicine, NC Baptist Hospital, 2007
  • Fellowship, Hematology And Oncology, WFU School of Medicine, 2011

Board Certifications

  • American Board of Internal Medicine, Hematology
  • American Board of Internal Medicine, Internal Medicine
  • American Board of Internal Medicine, Medical Oncology

NPI Number

  • 1265494413
Jimmy Ruiz, M.D.

Doctor Rating

No Rating Available
Why No Ratings?

Jimmy Ruiz, M.D.

Assistant Professor, Hematology & Oncology
Maya Angelou Center for Health Equity

Research Interests

Brain Neoplasms; Glioma; Carcinoma, Non-Small-Cell Lung; Lung Neoplasms; Procarbazine
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Contact Information

Academic: 336-716-0230 | Department: 336-716-4464

Recent Publications

Predictors of neurologic and nonneurologic death in patients with brain metastasis initially treated with upfront stereotactic radiosurgery without whole-brain radiation therapy. McTyre ER, Johnson AG, Ruiz J, Isom S, Lucas JT Jr, Hinson WH, Watabe K, Laxton AW, Tatter SB, Chan MD.. Neuro Oncol. 2017;19(4):558-566.

The effects of smoking status and smoking history on patients with brain metastases from lung cancer. Shenker RF, McTyre ER, Ruiz J, Weaver KE, Cramer C, Alphonse-Sullivan NK, Farris M, Petty WJ, Bonomi MR, Watabe K, Laxton AW, Tatter SB, Warren GW, Chan MD.. Cancer Med. 2017;6(5):944-952.

Recent advances in radiosurgical management of brain metastases. Devoid HM, McTyre ER, Page BR, Metheny-Barlow L, Ruiz J, Chan MD.. Front Biosci (Schol Ed). 2016;8():203-214.

Treatment of brain metastases of lung cancer in the era of precision medicine. Haughton ME, Chan MD, Watabe K, Bonomi M, Debinski W, Lesser GJ, Ruiz J.. Front Biosci (Elite Ed). 2016;8():219-232.

Prognostic molecular subtypes of low-grade cancer of the appendix. Levine EA, Votanopoulos KI, Qasem SA, Philip J, Cummins KA, Chou JW, Ruiz J, D'Agostino R, Shen P, Miller LD.. J Am Coll Surg. 2016;222(4):493-503.

Negative predictive value of granulomas on EBUS-TBNA in suspected extrathoracic malignancy. Bellinger CR, Sharma D, Ruiz J, Parks G, Dotson T, Haponik EF.. Lung. 2016;194(3):387-391.

Repeat stereotactic radiosurgery as salvage therapy for locally recurrent brain metastases previously treated with radiosurgery. McKay WH, McTyre ER, Okoukoni C, Alphonse-Sullivan NK, Ruiz J, Munley MT, Qasem S, Lo HW, Xing F, Laxton AW, Tatter SB, Watabe K, Chan MD.. J Neurosurg. 2016;():.

Brain metastasis velocity: a novel prognostic metric predictive of overall survival and freedom from whole-brain radiation therapy after upfront radiosurgery alone for brain metastases [abstract]. Farris M, McTyre E, Hughes RT, Ayala-Peacock DN, Randolph DM II, Bourland JD, Tatter SB, Laxton AW, Watabe K, Ruiz J, Li W, Zhou X, Chan MD.. Int J Radiat Oncol Biol Phys. 2016;96(2 Suppl):S180.

A phase II clinical trial of CPI-613 in patients with relapsed or refractory small cell lung carcinoma. Lycan TW, Pardee TS, Petty WJ, Bonomi M, Alistar A, Lamar ZS, Isom S, Chan MD, Miller AA, Ruiz J.. PLoS One. 2016;11(10):e0164244.

Local control of brain metastases after stereotactic radiosurgery: the impact of whole brain radiotherapy and treatment paradigm. Hughes RT, Black PJ, Page BR, Lucas JT, Qasem SA, Watabe K, Ruiz J, Laxton AW, Tatter SB, Debinski W, Chan MD.. J Radiosurg SBRT. 2016;4(2):89-96.

Clinical perspective on PROSE: does VeriStrat testing improve selection of second-line treatment for patients with non-small cell lung cancer? [editorial]. Ruiz J, Petty WJ.. Ann Transl Med. 2015;3(3):31.

Impact of systemic targeted agents on the clinical outcomes of patients with brain metastases. Johnson AG, Ruiz J, Hughes R, Page BR, Isom S, Lucas JT, McTyre ER, Houseknecht KW, Ayala-Peacock DN, Bourland DJ, Hinson WH, Laxton AW, Tatter SB, Debinski W, Watabe K, Chan MD.. Oncotarget. 2015;6(22):18945-55.

A phase 1, open-label, dose-escalation study of SNX-5422 plus carboplatin and paclitaxel in subjects with advanced lung cancers [abstract]. Gutierrez M, Giaccone G, Harper HD, Liu SV, Fang B, Ruiz J, Hinson JM, Orlemans EO, Drilon AE.. J Clin Oncol. 2015;33(15 Suppl):e19033.

Non-small cell lung cancer molecular genetic yield with small volume samples [abstract]. Bellinger C, Dotson T, Ruiz J.. Chest. 2015;148(4 Suppl):558A.

Molecular subtyping in advanced non-small cell lung cancer, a minimally invasive strategy with small volume fine needle aspirates [abstract]. Hansen K, Miller L, Dotson T, Bellinger C, Parks G, Cappellari J, Clark H, Howard C, Bolemon B, Petty WJ, Craddock L, Ruiz J.. J Thorac Oncol. 2015;10(9 Suppl 2):S701.

A competing risks analysis assessing predictors of neurologic and non-neurologic death in patients with brain metastasis initially treated with upfront stereotactic radiosurgery without whole-brain radiation therapy [abstract]. McTyre E, Johnson A, Ruiz J, Isom S, Lucas JT Jr, Hinson W, Watabe K, Laxton AW, Tatter SB, Chan MD.. Int J Radiat Oncol Biol Phys. 2015;93(3 Suppl):S176.

Impact of socioeconomic status on brain metastasis outcomes at a large academic radiosurgery center [abstract]. Houseknecht K, Taksler GB, Johnson A, Page BR, Hinson W, Laxton AW, Tatter SB, Weaver KE, Chan MD, Ruiz J.. Int J Radiat Oncol Biol Phys. 2015;93(3 Suppl):E366.

Growing a thoracic oncology program [abstract]. Bellinger CR, Hovda J, Petty WJ, Ruiz J, Dotson TL, Wudel LJ.. Am J Respir Crit Care Med. 2015;191():A5086.

Interactions between immunity, proliferation and molecular subtype in breast cancer prognosis. Nagalla S, Chou JW, Willingham MC, Ruiz J, Vaughn JP, Dubey P, Lash TL, Hamilton-Dutoit SJ, Bergh J, Sotiriou C, Black MA, Miller LD.. Genome Biol. 2013;14(4):R34.

A phase II trial of thalidomide and procarbazine in adult patients with recurrent or progressive malignant gliomas. Ruiz J, Case D, Enevold G, Rosdhal R, Tatter SB, Ellis TL, McQuellon RP, McMullen KP, Stieber VW, Shaw EG, Lesser GJ.. J Neurooncol. 2012;106(3):611-617.

Microarray gene expression patterns recapitulated on a clinically tractable diagnostic platform using breast and lung cancer formalin-fixed paraffin-embedded tissues [abstract]. Ruiz J, Chou J, Geisinger KR, Schoppe CH, Miller AA, Willingham MC, Petty WJ, Bolemon BH, Miller LD.. J Clin Oncol. 2011;29(Suppl):e21027.

A comprehensive 3-year internal medicine residency research curriculum. Ruiz J, Wallace EL, Miller DP, Loeser RF, Miles M, DuBose TD, Lichstein PR.. Am J Med. 2011;124(5):469-473.

A novel prognostic transcriptional signature for early stage non-small cell lung cancer [abstract]. Ruiz J, Miller AA, Petty WJ, Chou JW, Miller LD.. J Thorac Oncol. 2010;5(12 Suppl 7):S505.

Low-grade gliomas. Ruiz J, Lesser GJ.. Curr Treat Options Oncol. 2009;10(3-4):231-242.

Myocardial infarction in thrombotic thrombocytopenic purpura: a single-center experience and literature review. Wahla AS, Ruiz J, Noureddine N, Upadhya B, Sane DC, Owen J.. Eur J Haematol. 2008;81(4):311-316.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Assistant Professor, Hematology & Oncology

Clinical Interests

Lung Cancer, Thoracic Cancer
Jimmy Ruiz, M.D.

Jimmy Ruiz, M.D.

Assistant Professor, Hematology & Oncology
Maya Angelou Center for Health Equity

CP concern for questions/worries
CP efforts to include in decisions
CP explanations of prob/condition
CP spoke using clear language
Friendliness/courtesy of CP
Likelihood of recommending CP
Patients' confidence in CP
Time CP spent with patient
Wait time at clinic

Patient Comments

Comments are taken from the Care Provider section of the Press Ganey Patient Satisfaction Survey. Comments are posted exactly as they are written. Comments are added weekly. To protect patient privacy and confidentiality, patient names are not included.


Completely thorough about treatments and course of future treatments & testing.




No bad.


Dr. Jimmy Ruiz is the ONLY doctor I have/had any respect for and confidence in.


I think *Dr. Ruiz is the best possible Dr. I could have.

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