Profile

Elizabeth Hiltbold Schwartz, Ph.D.

Elizabeth Hiltbold Schwartz, Ph.D.

Assistant Professor, Microbiology & Immunology
Comprehensive Cancer Center
Translational Science Institute
Translational Science Institute
Contact Information
Office:
336-716-2011
Email: bhiltbol@wakehealth.edu
Education & Training
  PhDEmory University1996
FellowshipAllergy & ImmunologyUniversity of Pittsburgh1999
  Allergy & ImmunologyNational Institutes Hlth2002
Elizabeth Hiltbold Schwartz, Ph.D.

Elizabeth Hiltbold Schwartz, Ph.D.

Assistant Professor, Microbiology & Immunology
Comprehensive Cancer Center
Translational Science Institute
Translational Science Institute
Contact Information
Office:
336-716-2011
Email: bhiltbol@wakehealth.edu
Research Interests
cancer/oncogenesis , immunology/allergy/inflammatio , vaccines
Recent Publications
Surendran N, Hiltbold EM, Heid B, Sriranganathan N, Boyle SM, Zimmerman KL, Makris MR, Witonsky SG. Live Brucella abortus rough vaccine strain RB51 stimulates enhanced innate immune response in vitro compared to rough vaccine strain RB51SOD and virulent smooth strain 2308 in murine bone marrow-derived dendritic cells. Vet Microbiol. 2011; 147(1-2):75-82.


Mitchell LM, Brzoza-Lewis KL, Henry CJ, Grayson JM, Westcott MM, Hiltbold EM. Distinct responses of splenic dendritic cell subsets to infection with Listeria monocytogenes: maturation phenotype, level of infection, and T cell priming capacity ex vivo. Cell Immunol. 2011; 268(2):79-86.


Surendran N, Sriranganathan N, Lawler H, Boyle SM, Hiltbold EM, Heid B, Zimmerman K, Witonsky SG. Efficacy of vaccination strategies against intranasal challenge with Brucella abortus in BALB/c mice. Vaccine. 2011; 29(15):2749-2755.


Hoth JJ, Wells JD, Hiltbold EM, McCall CE, Yoza BK. Mechanism of neutrophil recruitment to the lung after pulmonary contusion. Shock. 2011; 35(6):604-609.


Henry CJ, Grayson JM, Brzoza-Lewis K, Mitchell LM, Westcott MM, Cook AS, Hiltbold EM. The roles of IL-12 and IL-23 in CD8+ T cell-mediated immunity against Listeria monocytogenes: insights from a DC vaccination model. Cell Immunol. 2010; 264(1):23-31.


Westcott MM, Henry CJ, Amis JE, Hiltbold EM. Dendritic cells inhibit the progression of Listeria monocytogenes intracellular infection by retaining bacteria in major histocompatibility complex class II-rich phagosomes and by limiting cytosolic growth. Infect Immun. 2010; 78(7):2956-2965.


Zhu X, Owen JS, Wilson MD, Li H, Griffiths GL, Thomas MJ, Hiltbold EM, Fessler MB, Parks JS. Macrophage ABCA1 reduces MyD88-dependent Toll-like receptor trafficking to lipid rafts by reduction of lipid raft cholesterol. J Lipid Res. 2010; 51(11):3196-3206.


Olex AL, Hiltbold EM, Leng X, Fetrow JS. Dynamics of dendritic cell maturation are identified through a novel filtering strategy applied to biological time-course microarray replicates. BMC Immunol. 2010; 11():article 41.


Surendran N, Hiltbold EM, Heid B, Sriranganathan N, Boyle SM, Zimmerman KL, Witonsky SG. Heat-killed and gamma-irradiated Brucella strain RB51 stimulates enhanced dendritic cell activation, but not function compared with the virulent smooth strain 2308. FEMS Immunol Med Microbiol. 2010; 60(2):147-155.


Surendran N, Zimmerman K, Seleem MN, Sriranganathan N, Boyle SM, Hiltbold EM, Lawler H, Heid B, Witonsky SG. Ability of Brucella abortus rough vaccine strains to elicit DC and innate immunity in lung using a murine respiratory model. Vaccine. 2010; 28(43):7009-7015.


Ahmed M, Mitchell LM, Puckett S, Brzoza-Lewis KL, Lyles DS, Hiltbold EM. Vesicular stomatitis virus M protein mutant stimulates maturation of Toll-like receptor 7 (TLR7)-positive dendritic cells through TLR-dependent and -independent mechanisms. J Virol. 2009; 83(7):2962-2975.


Hoth JJ, Wells JD, Brownlee NA, Hiltbold EM, Meredith JW, McCall CE, Yoza BK. Toll-like receptor 4-dependent responses to lung injury in a murine model of pulmonary contusion. Shock. 2009; 31(4):376-381.


Zhu XW, Owen JS, Wilson M, Thomas MJ, Hiltbold E, Fessler MB, Parks JS. Macrophage ABCA1 functions as an inhibitor of inflammation through modulation of cellular free cholesterol content [abstract]. Arterioscler Thromb Vasc Biol. 2009; 29(7):e63.


Zhu X, Lee J-Y, Hiltbold E, Maeda N, Parks JS. Macrophage ABCA1 dampens inflammation by modulation of free cholesterol distribution in membrane lipid rafts [abstract]. Arterioscler Thromb Vasc Biol. 2008; 28(6):e-126.


Yammani RD, Pejawar-Gaddy S, Gurley TC, Weimer ET, Hiltbold EM, Alexander-Miller MA. Regulation of maturation and activating potential in CD8+ versus CD8- dendritic cells following in vivo infection with vaccinia virus. Virology. 2008; 378(1):142-150.


Zhu X, Lee J-Y, Timmins JM, Brown JM, Boudyguina E, Mulya A, Gebre AK, Willingham MC, Mishra N, Parks JS, et al. Increased cellular free cholesterol in macrophage-specific Abca1 knock-out mice enhances pro-inflammatory response of macrophages. J Biol Chem. 2008; 283(34):22930-41.


Henry CJ, Ornelles DA, Mitchell LM, Brzoza-Lewis KL, Hiltbold EM. IL-12 produced by dendritic cells augments CD8+ T cell activation through the production of the chemokines CCL1 and CCL17. J Immunol. 2008; 181(12):8576-8584.


Westcott MM, Henry CJ, Cook AS, Grant KW, Hiltbold EM. Differential susceptibility of bone marrow-derived dendritic cells and macrophages to productive infection with Listeria monocytogenes. Cell Microbiol. 2007; 9(6):1397-1411.


Hoth JJ, Hudson WP, Brownlee NA, Yoza BK, Hiltbold EM, Meredith JW, McCall CE. Toll-like receptor 2 participates in the response to lung injury in a murine model of pulmonary contusion. Shock. 2007; 28(4):447-452.


Mitchell LM, Hiltbold EM. Activation of plasmacytoid dendritic cells by the intracellular pathogen listeria monocytogenes [abstract]. J Immunol. 2006; 176(Suppl):S106.


Henry CJ, Hiltbold E. IL-12 exerts its effects during the first 48 hours of T cell priming leading to stable conjugate formation and robust INF-gamma production [abstract]. J Immunol. 2006; 176(Suppl):S13-S14.


Brzoza KL, Hiltbold EM. TLR2 inhibits specific aspects of mDC maturation induced by Listeria monocytogenes [abstract]. J Immunol. 2006; 176(Suppl):S114.


Cook AS, Westcott M, Hiltbold E. Establishing the relationship between Listeria monocytogenes infection and dendritic cell maturation [abstract]. J Immunol. 2006; 176(Suppl):S110.
All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

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Last Updated 12/13/2011
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