Susan Sergeant, Ph.D., Assistant Professor Biochemistry

Susan Sergeant, Ph.D.

Assistant Professor, Biochemistry

Contact Information

Academic: 336-716-7388 | Department: 336-716-7388

Email: ssergean@wakehealth.edu

Education & Training

Ph.D., University of Missouri-Columbia , 1987
B.S., Washington College , 1981
Fellowship, WFU School of Medicine, 1998

Memberships

Soc for Leukocyte Biology

Susan Sergeant, Ph.D.

Assistant Professor, Biochemistry

Contact Information

Academic: 336-716-7388 | Department: 336-716-7388

Email: ssergean@wakehealth.edu

Recent Publications

Sergeant S, Hugenschmidt CE, Rudock ME, Ziegler JT, Ivester P, Ainsworth HC, Vaidya D, Case LD, Langefeld CD, Freedman BI, Bowden DW, Mathias RA, Chilton FH. Differences in arachidonic acid levels and fatty acid desaturase (FADS) gene variants in African Americans and European Americans with diabetes or the metabolic syndrome. Br J Nutr. 2012;107(4):547-555.

Mishra M, Byrd MS, Sergeant S, Azad AK, Parsek MR, McPhail L, Schlesinger LS, Wozniak DJ. Pseudomonas aeruginosa Psl polysaccharide reduces neutrophil phagocytosis and the oxidative response by limiting complement-mediated opsonization. Cell Microbiol. 2012;14(1):95-106.

Mathias RA, Fu W, Akey JM, Ainsworth HC, Torgerson DG, Ruczinski I, Sergeant S, Barnes KC, Chilton FH. Adaptive evolution of the FADS gene cluster within Africa. PLoS One. 2012;7(9):e44926.

Sergeant S, Lee TC, Ivester P, Ainsworth HC, Case LD, Chilton FH. Botanical oil supplementation alters insulin levels in diabetic/metabolic syndrome subjects in a genotypic-specific manner [abstract]. FASEB J. 2012;26(Meeting Abstracts Suppl):647.11.

Wilson BA, Sergeant S, Ainsworth H, Mathias R, Chilton FH III. Racial differences in plasma omega-3 long chain fatty acid levels in a cohort of African Americans and European Americans with diabetes and metabolic syndrome [abstract]. FASEB J. 2012;26(Meeting Abstracts Suppl):266.4.

Sergeant S, McQuail JA, Riddle DR, Chilton FH, Ortmeier SB, Jessup JA, Groban L, Nicolle MM. Dietary fish oil modestly attenuates the effect of age on diastolic function but has no effect on memory or brain inflammation in aged rats. J Gerontol A Biol Sci Med Sci. 2011;66(5):521-533.

Mathias RA, Sergeant S, Hugenschmidt CE, Ziegler JT, Ivester P, Case D, Freedman BI, Rudock ME, Langefeld CD, Bowden DW, Chilton FH, et al. The impact of FADS genetic variants on omega-6 polyunsaturated fatty acid metabolism in African Americans. BMC Genet. 2011;12():article 50.

Chilton FH, Lee TC, Willard SL, Ivester P, Sergeant S, Register TC, Shively CA. Depression and altered serum lipids in cynomolgus monkeys consuming a Western diet. Physiol Behav. 2011;104(2):222-227.

Lewis EM, Sergeant S, Ledford B, Stull N, Dinauer MC, McPhail LC. Phosphorylation of p22phox on threonine 147 enhances NADPH oxidase activity by promoting p47phox binding. J Biol Chem. 2010;285(5):2959-2967.

Mathias RA, Vergara C, Gao L, Rafaels N, Hand T, Campbell M, Bickel C, Ivester P, Sergeant, Chilton FH, et al. FADS genetic variants and omega-6 polyunsaturated fatty acid metabolism in a homogeneous island population. J Lipid Res. 2010;51(9):2766-2774.

Ivester P, Sergeant S, Danhauer SC, Case LD, Lamb A, Chilton BG, Delar B, Hollingshead ML, Weaver KL, Chilton FH. Effect of a multifaceted, church-based wellness program on metabolic syndrome in 41 overweight or obese congregants. Prev Chronic Dis. 2010;7(4):A81.

Wooten RE, Willingham MC, Daniel LW, Leslie CC, Rogers LC, Sergeant S, O'Flaherty JT. Novel translocation responses of cytosolic phospholipase A2alpha fluorescent proteins. Biochim Biophys Acta. 2008;1783(8):1544-1550.

Lewis EM, Singla M, Sergeant S, Koty PP, McPhail LC. X-linked chronic granulomatous disease secondary to skewed X chromosome inactivation in a female with a novel CYBB mutation and late presentation. Clin Immunol. 2008;129(2):372-380.

Shen K, Sergeant S, Hantgan RR, McPhail LC, Horita DA. Mutations in the PX-SH3A linker of p47phox decouple PI(3,4)P2 binding from NADPH oxidase activation. Biochemistry. 2008;47(34):8855-8865.

Sergeant S, McPhail LC. Measurement of phospholipid metabolism in intact neutrophils. Methods Mol Biol. 2007;412():69-83.