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Hossam Abdelnaby Shaltout, Ph.D.Wake Forest School of Medicine

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Hossam Abdelnaby Shaltout, Ph.D.

Assistant Professor,

Contact Information

New Patient Appointments: 336-716-WAKE
Returning Patient Appointments: 336-716-6476
Department: 336-716-4594

Email: hshaltou@wakehealth.edu

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Additional Languages

Arabic

Education & Training

  • Ph.D., East Carolina University, 2005
Hossam Abdelnaby Shaltout, Ph.D.

Doctor Rating

No Rating Available
Why No Ratings?

Hossam Abdelnaby Shaltout, Ph.D.

Assistant Professor, Obstetrics & Gynecology

Research Interests

cardiac function, vascular diseases

Contact Information

Academic: 336-716-1251 | Department: 336-716-4594

Email: hshaltou@wakehealth.edu

Recent Publications

Jefferson ME, Nicklas BJ, Chmelo EA, Crotts CI, Shaltout HA, Diz DI, Marsh AP, Brinkley TE. Effects of resistance training with and without caloric restriction on arterial stiffness in overweight and obese older adults. Am J Hypertens. 2016;29(4):494-500.

Fortunato JE, Tegeler CL, Gerdes L, Lee SW, Pajewski NM, Franco ME, Cook JF, Shaltout HA, Tegeler CH. Use of an allostatic neurotechnology by adolescents with postural orthostatic tachycardia syndrome (POTS) is associated with improvements in heart rate variability and changes in temporal lobe electrical activity. Exp Brain Res. 2016;234(3):791-798.

Wagoner AL, Shaltout HA, Fortunato JE, Diz DI. Distinct neurohumoral biomarker profiles in children with hemodynamically defined orthostatic intolerance may predict treatment options. Am J Physiol Heart Circ Physiol. 2016;310(3):H416-H425.

Yamaleyeva LM, Brosnihan KB, Mcgee C, Shi S, Varagic J, Bader M, Dechend R, Shaltout H. Hemodynamic and renoprotective actions of (Pyr1)-Apelin-13 in preeclampsia [abstract]. Reprod Sci. 2016;23(Suppl 1):62A.

Yamaleyeva LM, Shaltout HA, Varagic J. Apelin-13 in blood pressure regulation and cardiovascular disease. Curr Opin Nephrol Hypertens. 2016;():.

Schaich CL, Grabenauer M, Thomas BF, Shaltout HA, Gallagher PE, Howlett AC, Diz DI. Medullary endocannabinoids contribute to the differential resting baroreflex sensitivity in rats with altered brain renin-angiotensin system expression. Front Physiol. 2016;7():207.

Tegeler C, Tegeler C, Cook J, Howard L, Lee S, Shaltout H. Durability of symptom reductions associated with use of HIRREM by military personnel with traumatic stress [abstract]. Neurology. 2016;86(16 Suppl):A18.007.

Hendricks AS, Diz DI, Shaltout HA, Chappell MC. Sex specific differences in key signaling pathways involved in sympathetic nervous system control within the dorsal medulla of adult sheep with fetal betamethasone exposure [abstract]. FASEB J. 2016;30(1 Suppl):716.5.

Duncan AV, Shaltout HA, Tommasi EN, Gallagher PE, Tallant EA, Diz DI. Beneficial cardiovascular effects of muscadine grape extract in normotensive female rats [abstract]. FASEB J. 2016;30(1 Suppl):1175.7.

Tegeler C, Shaltout H, Lee S, Tegeler C. Military personnel with traumatic stress demonstrate improved autonomic cardiovascular regulation after use of a closed loop neurotechnology [abstract]. Neurology. 2016;86(16 Suppl):P5.122.

Tegeler C, Tegeler C, Cook J, Lee S, Shaltout H, Laurienti P. Military personnel with traumatic stress show changes in large-scale brain networks after use of a closed-loop neurotechnology [abstract]. Neurology. 2016;86(16 Suppl):A17.009.

El-Bassossy HM, Shaltout HA. Allopurinol alleviates hypertension and proteinuria in high fructose, high salt and high fat induced model of metabolic syndrome. Transl Res. 2015;165(5):621-630.

Schaich CL, Shaltout HA, Grabenauer M, Thomas BF, Gallagher PE, Howlett AC, Diz DI. Alterations in the medullary endocannabinoid system contribute to age-related impairment of baroreflex sensitivity. J Cardiovasc Pharmacol. 2015;65(5):473-479.

Tegeler CH, Shaltout HA, Tegeler CL, Gerdes L, Lee SW. Rightward dominance in temporal high-frequency electrical asymmetry corresponds to higher resting heart rate and lower baroreflex sensitivity in a heterogeneous population. Brain Behav. 2015;5(6):e00343.

Lawson MJ, Figueroa JP, Rose JC, Chappell MC, Diz DI, Shaltout HA. Intracerebroventricular infusion of angiotensin-(1-7) improves baroreflex sensitivity in antenatal betamethasone exposed sheep [abstract]. FASEB J. 2015;29(1 Suppl):811.30.

Lawson MJ, Shaltout HA, Chappell MC, Diz DI, Figueroa JP. Obesity induces further autonomic impairment in sheep exposed antenatally to betamethasone [abstract]. FASEB J. 2015;29(1 Suppl):LB724.

Shaltout HA, Glock MS. Low serum vitamin D is associated with greater impairment in autonomic function upon head up tilt in children with orthostatic intolerance [abstract]. Hypertension. 2015;66(Suppl 1):AP633.

Yamaleyeva LM, Brosnihan KB, McGee C, Shi S, Varagic J, Bader M, Dechend R, Shaltout HA. Systemic administration of (Pyr1)-apelin-13 at late pregnancy reduces blood pressure, proteinuria, and improves autonomic function in preeclamptic rats [abstract]. Hypertension. 2015;66(Suppl 1):A126.

Diz DI, Olson J, Bourland JD, Kitzman D, Carr JJ, Kritchevsky SB, Groban L, Shaltout HA. Distinct profiles of brain medullary metabolites detected by 1H-magnetic resonance spectroscopy correlate with indices of autonomic function and visceral fat in healthy adults [abstract]. Hypertension. 2015;66(Suppl 1):AP149.

Diz DI, Tommasi EN, Howlett AC, Shaltout HA. Angiotensin II - endocannabinoid interactions in the nucleus of the solitary tract are important for regulation of baroreflex control of heart rate [abstract]. Hypertension. 2015;66(Suppl 1):AP189.

Lawson MJ, Figueroa JP, Chappell MC, Diz DI, Shaltout HA. Intracerebroventricular (ICV) infusion of angiotensin-(1-7) lowers blood pressure and improves autonomic function in antenatal betamethasone exposed sheep [abstract]. Hypertension. 2015;66(Suppl 1):A081.

Wagoner AL, Olson JD, Fortunato JE, Diz DI, Shaltout HA. 1H-magnetic resonance spectroscopy reveals elevation of myoInositol and other markers of inflammation in the dorsal medulla of children with orthostatic intolerance [abstract]. Hypertension. 2015;66(Suppl 1):AP069.

Shaltout HA, Yamaleyeva LM, Bader M, Dechend R, Brosnihan B. Impairment of autonomic function precedes blood pressure elevation in rat model of pre-eclampsia [abstract]. Hypertension. 2015;66(Suppl 1):AP175.

Tegeler CH, Laurienti PJ, Tegeler CL, Cook JF, Wistermayer PR, Lee SW, Shaltout HA. Military personnel with traumatic stress demonstrate changes in the default mode network after use of a closed-loop neurotechnology [abstract]. Ann Neurol. 2015;78(Suppl 19):S22.

Chappell MC, Marshall AC, Alzayadneh EM, Shaltout HA, Diz DI. Update on the angiotensin converting enzyme 2-angiotensin (1-7)-Mas receptor axis: fetal programing, sex differences, and intracellular pathways. Front Endocrinol (Lausanne). 2014;4():201.

Tegeler CH, Lee SW, Shaltout HA. Significance of right anterior insula activity for mental health intervention [letter]. JAMA Psychiatry. 2014;71(3):336.

Marshall AC, Shaltout HA, Pirro NT, Rose JC, Diz DI, Chappell MC. Enhanced activity of an angiotensin-(1-7) neuropeptidase in glucocorticoid-induced fetal programming. Peptides. 2014;52():74-81.

Tegeler C, Tegeler C, Cook J, Lee S, Franco M, Gerdes L, Shaltout H. Use of HIRREM, a noninvasive neurotechnology, is associated with symptom reduction and increased heart rate variability among individuals with traumatic brain injury [abstract]. Brain Inj. 2014;28(5-6):818-819.

Tarbell SE, Shaltout HA, Wagoner AL, Diz DI, Fortunato JE. Relationship among nausea, anxiety, and orthostatic symptoms in pediatric patients with chronic unexplained nausea. Exp Brain Res. 2014;232(8):2645-2650.

Tegeler CH, Tegeler CL, Cook JF, Lee SW, Franco ME, Gerdes L, Shaltout HA. Use of a non-invasive neurotechnology, HIRREM, is associated with improved sleep, mood, and baroreflex sensitivity in athletes with persisting post-concussion symptoms [abstract]. Neurology. 2014;82(10 Suppl):P5.313.

Cook JF, Tegeler CL, Lee SW, Shaltout HA, Franco ME, Tegeler CH. Use of a non-invasive neurotechnology, HIRREM, is associated with improved sleep and mood in a heterogeneous cohort [abstract]. Neurology. 2014;82(10 Suppl):P5.287.

Tegeler CH, Cook JF, Tegeler CL, Lee SW, Nicholas JN, Shaltout HA. Use of HIRREM, a non-invasive neurotechnology, is associated with improved autonomic function and decreased temporal hemispheric asymmetry in a 67 year old male with a recent stroke [abstract]. Neurology. 2014;82(10 Suppl):P1.138.

Tegeler CH, Tegeler CL, Cook JF, Lee SW, Franco ME, Nicholas JN, Ray CE, Howard LJ, Shaltout HA. A noninvasive approach to improve insomnia in a military cohort [abstract]. Sleep. 2014;37(Abstract Suppl):A192.0551.

de Lima DC, Nascimento K, Shaltout HA, Coimbra CC, Diz DI. The metabolic challenge induced by hypercaloric diet leads to increased activity of the HPA axis and cardiac autonomic dysfunction in rats with low glial angiotensinogen [abstract]. FASEB J. 2014;28(1 Suppl):831.3.

Fortunato JE, Wagoner AL, Harbinson RL, D'Agostino RB Jr, Shaltout HA, Diz DI. Effect of fludrocortisone acetate on chronic unexplained nausea and abdominal pain in children with orthostatic intolerance. J Pediatr Gastroenterol Nutr. 2014;59(1):39-43.

Lee SW, Gerdes L, Tegeler CL, Shaltout HA, Tegeler CH. A bihemispheric autonomic model for traumatic stress effects on health and behavior. Front Psychol. 2014;5():843.

Schaich CL, Shaltout HA, Brosnihan KB, Howlett AC, Diz DI. Acute and chronic systemic CB1 cannabinoid receptor blockade improves blood pressure regulation and metabolic profile in hypertensive (mRen2)27 rats. Physiol Rep. 2014;2(8):e12108.

Shaltout HA, Wagoner AL, Fortunato JE, Diz DI. Impaired hemodynamic response to head up tilt in adolescents presenting with chronic nausea and orthostatic intolerance [abstract]. Hypertension. 2014;64(Suppl 1):A513.

Wagoner AL, Shaltout HA, Diz DI, Fortunato JE. Novel neurohumoral responses to head upright tilt testing in children with chronic nausea and orthostatic intolerance [abstract]. Hypertension. 2014;64(Suppl 1):A033.

Tegeler CH, Tegeler CL, Cook JF, Lee SW, Shaltout HA. Use of a closed-loop neurotechnology, HIR-REM, is associated with symptom reduction and improved autonomic regulation in migraineurs [abstract]. Ann Neurol. 2014;76(Suppl 18):S104.

Shaltout HA, Marsh AP, Laurienti P, Basu S, Klebous CC, Kus N, Morgan A, DosSantos PC, Norris JL, Miller G, Rejeski J, Hawfield AT, Diz DI, Kim-Shapiro DB. Effect of adding beet root juice to exercise on physical performance and cardiovascular measures in old hypertensive subjects [abstract]. Hypertension. 2014;64(Suppl 1):A462.

Nautiyal M, Shaltout HA, de Lima DC, do Nascimento K, Chappell MC, Diz DI. Response to angiotensin-(1-7) and bradykinin in baroreceptor reflex sensitivity in hypertension [letter]. Hypertension. 2013;61(2):e20.

Marshall AC, Shaltout HA, Nautiyal M, Rose JC, Chappell MC, Diz DI. Fetal betamethasone exposure attenuates angiotensin-(1-7)-Mas receptor expression in the dorsal medulla of adult sheep. Peptides. 2013;44(C):25-31.

Marshall AC, Shaltout HA, Pirro NT, Rose JC, Diz DI, Chappell MC. Differential expression of renin-angiotensin system components in the choroid plexus of betamethasone exposed and control sheep [abstract]. FASEB J. 2013;27(Meeting Abstracts):1107.12.

Nautiyal M, Shaltout HA, Chappell MC, Diz DI. Reduction in central mitochondrial ROS improves cardiovagal baroreflex function independent of blood pressure in (mRen2)27 rats [abstract]. FASEB J. 2013;27(Meeting Abstracts):890.4.

Marshall AC, Shaltout HA, Pirro NT, Rose JC, Diz DI, Chappell MC. Antenatal betamethasone exposure is associated with lower ANG-(1-7) and increased ACE in the CSF of adult sheep. Am J Physiol Regul Integr Comp Physiol. 2013;305(7):R679-R688.

Marshall AC, Shaltout HA, Pirro NT, Rose JC, Diz DI, Chappell MC. Antenatal betamethasone exposure reduces Ang-(1-7) but enhances angiotensin-converting enzyme and a thiol peptidase to metabolize Ang-(1-7) in the cerebrospinal fluid [abstract]. Hypertension. 2013;62(3 Suppl):177.

Nautiyal M, Shaltout HA, Chappell MC, Diz DI. Combined intracerebroventricular angiotensin-(1-7) and candesartan normalizes blood pressure and improves baroreflex function in transgenic (mRen2)27 hypertensive rats [abstract]. Hypertension. 2013;62(3 Suppl):607.

Fortunato JE, Wagoner AL, Shaltout HA, Diz DI. Increase in arginine vasopressin is associated with the reduction in blood pressure in patients with chronic nausea and orthostatic intolerance [abstract]. J Pediatr Gastroenterol Nutr. 2013;57(Suppl 1):e97.

Tegeler C, Lee SW, Tegeler CL, Shaltout HA. Correlation between temporal lobe EEG asymmetry and heart rate variability [abstract]. Neurology. 2013;80(Suppl):P03031.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Assistant Professor, Obstetrics & Gynecology

Hossam Abdelnaby Shaltout, Ph.D.

Hossam Abdelnaby Shaltout, Ph.D.

Assistant Professor, Obstetrics & Gynecology

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