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Hossam Abdelnaby Shaltout, Ph.D.Wake Forest School of Medicine

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Hossam Abdelnaby Shaltout, Ph.D.

Associate Professor,

Contact Information

Returning Patient Appointments: 336-716-6476
Department: 336-716-4594

Email: hshaltou@wakehealth.edu

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Additional Languages

Arabic

Education & Training

  • Ph.D., East Carolina University, 2005
Hossam Abdelnaby Shaltout, Ph.D.

Doctor Rating

No Rating Available
Why No Ratings?

Hossam Abdelnaby Shaltout, Ph.D.

Associate Professor, Obstetrics & Gynecology
Office of Women in Medicine and Science

Research Interests

Baroreflex; Heart Rate; Betamethasone; Prenatal Exposure Delayed Effects; Autonomic Nervous System
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Contact Information

Academic: 336-716-1251 | Department: 336-716-4594

Email: hshaltou@wakehealth.edu

Recent Publications

Preterm adolescents exhibit higher blood pressure and sodium retention with higher uric acid and differential circulating renin-angiotensin system expression [abstract]. South AM, Nixon PA, Chappell MC, Diz DI, Jensen ET, Shaltout HA, Washburn LK.. FASEB J. 2018;32(1 Suppl):883.6.

Central effects of angiotensin-(1-7) treatment on medullary MAPK and PI3K pathways of antenatal glucocorticoid exposed adult sheep are sex dependent [abstract]. Hendricks AS, Shaltout HA, Chappell MC, Diz DI.. FASEB J. 2018;32(1 Suppl):697.3.

Improvements in heart rate variability, baroreflex sensitivity, and sleep after use of closed-loop allostatic neurotechnology by a heterogeneous cohort. Shaltout HA, Lee SW, Tegeler CL, Hirsch JR, Simpson SL, Gerdes L, Tegeler CH.. Front Public Health. 2018;6():116.

Association between preterm birth and the renin-angiotensin system in adolescence: influence of sex and obesity. South AM, Nixon PA, Chappell MC, Diz DI, Russell GB, Jensen ET, Shaltout HA, O?Shea TM, Washburn LK.. J Hypertens. 2018;():.

Antenatal steroid exposure and heart rate variability in adolescents born with very low birth weight. Nixon PA, Washburn LK, Michael O'Shea T, Shaltout HA, Russell GB, Snively BM, Rose JC.. Pediatr Res. 2017;81(1):57-62.

Antenatal corticosteroids and the renin-angiotensin-aldosterone system in adolescents born preterm. South AM, Nixon PA, Chappell MC, Diz DI, Russell GB, Snively BM, Shaltout HA, Rose JC, O'Shea TM, Washburn LK.. Pediatr Res. 2017;81(1):88-93.

Clinical, hemispheric, and autonomic changes associated with use of closed-loop, allostatic neurotechnology by a case series of individuals with self-reported symptoms of post-traumatic stress. Tegeler CH, Cook JF, Tegeler CL, Hirsch JR, Shaltout HA, Simpson SL, Fidali BC, Gerdes L, Lee SW.. BMC Psychiatry. 2017;17(1):141.

Antenatal corticosteroids and cardiometabolic outcomes in adolescents born with very low birth weight. Washburn LK, Nixon PA, Snively BM, Russell GB, Shaltout HA, South AM, O'Shea TM.. Pediatr Res. 2017;82(4):697-703.

Effects of supervised exercise and dietary nitrate in older adults with controlled hypertension and/or heart failure with preserved ejection fraction. Shaltout HA, Eggebeen J, Marsh AP, Brubaker PH, Laurienti PJ, Burdette JH, Basu S, Morgan A, Dos Santos PC, Norris JL, Morgan TM, Miller GD, Rejeski WJ, Hawfield AT, Diz DI, Becton JT, Kim-Shapiro DB, Kitzman DW.. Nitric Oxide. 2017;69():78-90.

In subjects with insomnia, use of a closed-loop acoustic stimulation neurotechnology improves heart rate variability and baroreflex sensitivity: results of a placebo-controlled clinical trial [abstract]. Shaltout HA, Tegeler CL, Lee SW, Tegeler CH.. Sleep. 2017;40(Abstract Suppl):A135.

Antenatal betamethasone fetal programming of cardiometabolic disease is reversed by removal of visceral adipose tissue early in life [abstract]. Shaltout HA, Massmann A, Figueroa J.. FASEB J. 2017;31(1 Suppl):997.5.

Fetal betamethasone exposure markedly attenuates the protein expression of angiotensin converting enzyme 2 but not dipeptidyl peptidase 3 within the brain dorsomedial medulla of adult female sheep [abstract]. Hendricks AS, Shaltout HA, Chappell MC, Diz DI.. FASEB J. 2017;31(1 Suppl):997.6.

Adult males of very low birth weight with antenatal corticosteroid exposure exhibit an enhanced blood pressure response to acute stress [abstract]. Washburn L, Chappell M, Beavers D, Diz D, Jensen E, Nixon P, Shaltout H, South A, Taylor R, Rose J.. FASEB J. 2017;31(1 Suppl):852.8.

Design and synthesis of some new 2,3'-bipyridine-5-carbonitriles as potential anti-inflammatory/antimicrobial agents. Elzahhar PA, Elkazaz S, Soliman R, El-Tombary AA, Shaltout HA, El-Ashmawy IM, Abdel Wahab AE, El-Hawash SA.. Future Med Chem. 2017;9(12):1413-1450.

Successful use of closed-loop allostatic neurotechnology for post-traumatic stress symptoms in military personnel: self-reported and autonomic improvements. Tegeler CL, Gerdes L, Shaltout HA, Cook JF, Simpson SL, Lee SW, Tegeler CH.. Mil Med Res. 2017;4():UNSP 38.

Influence of sex and obesity on the effect of preterm birth on the renin-angiotensin system in adolescents [abstract]. South AM, Nixon PA, Chappell MC, Diz DI, Russell GB, Jenson ET, Shaltout HA, Washburn LK.. Hypertension. 2017;70(Suppl 1):A051.

Obesity and alterations in renal function in adolescents born preterm with very low birth weight [abstract]. South AM, Nixon PA, Chappell MC, Diz DI, Russell GB, Jensen ET, Shaltout HA.. Hypertension. 2017;70(Suppl 1):AP123.

Gender-specific relationships between plasma levels of endocannabinoids and vagal and sympathetic control of heart rate in normotensive obese older adults [abstract]. Schaich CL, Shaltout HA, Kovach A, Grabenauer M, Thomas BF, Brinkley TE, Nicklas BJ, Diz DI.. Hypertension. 2017;70(Suppl 1):AP204.

Improved heart rate variability, and symptoms of insomnia and stress, with use of a closed-loop, allostatic neurotechnology in law enforcement officers [abstract]. Tegeler CL, Shaltout HA, Howard LJ, Schmidt KD, Garlin EI, Tegeler CH.. Hypertension. 2017;70(Suppl 1):AP484.

Use of a noninvasive, closed-loop, allostatic, neurotechnology reduced blood pressure and improved heart rate variability in a pre-hypertensive cohort [abstract]. Shaltout HA, Tegeler CL, Tegeler CH.. Hypertension. 2017;70(Suppl 1):AP485.

Healing a broken heart using a closed-loop, allostatic, neurotechnology: a case study in a patient suffering from Takotsubo syndrome [abstract]. Tegeler CH, Tegeler CL, Shaltout HA.. Hypertension. 2017;70(Suppl 1):AP483.

Central angiotensin-(1-7) treatment attenuates ERK 1/2 expression and oxidative stress in the dorsal medulla of betamethasone-exposed sheep that associates with improved blood pressure and baroreflex sensitivity [abstract]. Hendricks AS, Shaltout HA, Chappell MC, Diz DI.. Hypertension. 2017;70(Suppl 1):A145.

Effects of resistance training with and without caloric restriction on arterial stiffness in overweight and obese older adults. Jefferson ME, Nicklas BJ, Chmelo EA, Crotts CI, Shaltout HA, Diz DI, Marsh AP, Brinkley TE.. Am J Hypertens. 2016;29(4):494-500.

Use of an allostatic neurotechnology by adolescents with postural orthostatic tachycardia syndrome (POTS) is associated with improvements in heart rate variability and changes in temporal lobe electrical activity. Fortunato JE, Tegeler CL, Gerdes L, Lee SW, Pajewski NM, Franco ME, Cook JF, Shaltout HA, Tegeler CH.. Exp Brain Res. 2016;234(3):791-798.

Distinct neurohumoral biomarker profiles in children with hemodynamically defined orthostatic intolerance may predict treatment options. Wagoner AL, Shaltout HA, Fortunato JE, Diz DI.. Am J Physiol Heart Circ Physiol. 2016;310(3):H416-H425.

Hemodynamic and renoprotective actions of (Pyr1)-Apelin-13 in preeclampsia [abstract]. Yamaleyeva LM, Brosnihan KB, Mcgee C, Shi S, Varagic J, Bader M, Dechend R, Shaltout H.. Reprod Sci. 2016;23(Suppl 1):62A.

Apelin-13 in blood pressure regulation and cardiovascular disease. Yamaleyeva LM, Shaltout HA, Varagic J.. Curr Opin Nephrol Hypertens. 2016;25(5):396-403.

Medullary endocannabinoids contribute to the differential resting baroreflex sensitivity in rats with altered brain renin-angiotensin system expression. Schaich CL, Grabenauer M, Thomas BF, Shaltout HA, Gallagher PE, Howlett AC, Diz DI.. Front Physiol. 2016;7():207.

Durability of symptom reductions associated with use of HIRREM by military personnel with traumatic stress [abstract]. Tegeler C, Tegeler C, Cook J, Howard L, Lee S, Shaltout H.. Neurology. 2016;86(16 Suppl):A18.007.

Sex specific differences in key signaling pathways involved in sympathetic nervous system control within the dorsal medulla of adult sheep with fetal betamethasone exposure [abstract]. Hendricks AS, Diz DI, Shaltout HA, Chappell MC.. FASEB J. 2016;30(1 Suppl):716.5.

Beneficial cardiovascular effects of muscadine grape extract in normotensive female rats [abstract]. Duncan AV, Shaltout HA, Tommasi EN, Gallagher PE, Tallant EA, Diz DI.. FASEB J. 2016;30(1 Suppl):1175.7.

Military personnel with traumatic stress demonstrate improved autonomic cardiovascular regulation after use of a closed loop neurotechnology [abstract]. Tegeler C, Shaltout H, Lee S, Tegeler C.. Neurology. 2016;86(16 Suppl):P5.122.

Military personnel with traumatic stress show changes in large-scale brain networks after use of a closed-loop neurotechnology [abstract]. Tegeler C, Tegeler C, Cook J, Lee S, Shaltout H, Laurienti P.. Neurology. 2016;86(16 Suppl):A17.009.

A preliminary study of the effectiveness of an allostatic, closed-loop, acoustic stimulation neurotechnology in the treatment of athletes with persisting post-concussion symptoms. Tegeler CH, Tegeler CL, Cook JF, Lee SW, Gerdes L, Shaltout HA, Miles CM, Simpson SL.. Sports Med Open. 2016;2(1):39.

Influence of race and obesity on the renin-angiotensin-aldosterone system in adolescents born preterm [abstract]. South AM, Nixon PA, Chappell MC, Diz DI, Russell GB, Snively BM, Shaltout HA, Rose JC, O'Shea TM, Washburn LK.. Hypertension. 2016;68(Suppl 1):A136.

Antenatal corticosteroids and alterations in renal function in adolescents born preterm [abstract]. South AM, Nixon PA, Chappell MC, Diz DI, Russell GB, Snively BM, Shaltout HA, Rose JC, O'Shea TM, Washburn LK.. Hypertension. 2016;68(Suppl 1):AP121.

Improvement of autonomic function and C-reactive protein in military personnel with traumatic stress after use of a closed loop neurotechnology [abstract]. Shaltout HA, Tegeler CL, Tegeler CH.. Hypertension. 2016;68(Suppl 1):AP625.

Reduced symptoms and improved heart rate variability associated with use of closed-loop noninvasive neurotechnology by migraineurs [abstract]. Tegeler CL, Shaltout HA, Tegeler CH.. Hypertension. 2016;68(Suppl 1):AP602.

Improved autonomic cardiovascular regulation and reduced symptoms associated with use of closed-loop noninvasive neurotechnology by healthcare workers [abstract]. Tegeler CL, Shaltout HA, Howard LI, Tegeler CH.. Hypertension. 2016;68(Suppl 1):AP627.

Allopurinol alleviates hypertension and proteinuria in high fructose, high salt and high fat induced model of metabolic syndrome. El-Bassossy HM, Shaltout HA.. Transl Res. 2015;165(5):621-630.

Alterations in the medullary endocannabinoid system contribute to age-related impairment of baroreflex sensitivity. Schaich CL, Shaltout HA, Grabenauer M, Thomas BF, Gallagher PE, Howlett AC, Diz DI.. J Cardiovasc Pharmacol. 2015;65(5):473-479.

Rightward dominance in temporal high-frequency electrical asymmetry corresponds to higher resting heart rate and lower baroreflex sensitivity in a heterogeneous population. Tegeler CH, Shaltout HA, Tegeler CL, Gerdes L, Lee SW.. Brain Behav. 2015;5(6):e00343.

Intracerebroventricular infusion of angiotensin-(1-7) improves baroreflex sensitivity in antenatal betamethasone exposed sheep [abstract]. Lawson MJ, Figueroa JP, Rose JC, Chappell MC, Diz DI, Shaltout HA.. FASEB J. 2015;29(1 Suppl):811.30.

Obesity induces further autonomic impairment in sheep exposed antenatally to betamethasone [abstract]. Lawson MJ, Shaltout HA, Chappell MC, Diz DI, Figueroa JP.. FASEB J. 2015;29(1 Suppl):LB724.

Low serum vitamin D is associated with greater impairment in autonomic function upon head up tilt in children with orthostatic intolerance [abstract]. Shaltout HA, Glock MS.. Hypertension. 2015;66(Suppl 1):AP633.

Systemic administration of (Pyr1)-apelin-13 at late pregnancy reduces blood pressure, proteinuria, and improves autonomic function in preeclamptic rats [abstract]. Yamaleyeva LM, Brosnihan KB, McGee C, Shi S, Varagic J, Bader M, Dechend R, Shaltout HA.. Hypertension. 2015;66(Suppl 1):A126.

Distinct profiles of brain medullary metabolites detected by 1H-magnetic resonance spectroscopy correlate with indices of autonomic function and visceral fat in healthy adults [abstract]. Diz DI, Olson J, Bourland JD, Kitzman D, Carr JJ, Kritchevsky SB, Groban L, Shaltout HA.. Hypertension. 2015;66(Suppl 1):AP149.

Angiotensin II - endocannabinoid interactions in the nucleus of the solitary tract are important for regulation of baroreflex control of heart rate [abstract]. Diz DI, Tommasi EN, Howlett AC, Shaltout HA.. Hypertension. 2015;66(Suppl 1):AP189.

Intracerebroventricular (ICV) infusion of angiotensin-(1-7) lowers blood pressure and improves autonomic function in antenatal betamethasone exposed sheep [abstract]. Lawson MJ, Figueroa JP, Chappell MC, Diz DI, Shaltout HA.. Hypertension. 2015;66(Suppl 1):A081.

1H-magnetic resonance spectroscopy reveals elevation of myoInositol and other markers of inflammation in the dorsal medulla of children with orthostatic intolerance [abstract]. Wagoner AL, Olson JD, Fortunato JE, Diz DI, Shaltout HA.. Hypertension. 2015;66(Suppl 1):AP069.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Associate Professor, Obstetrics & Gynecology

Hossam Abdelnaby Shaltout, Ph.D.

Hossam Abdelnaby Shaltout, Ph.D.

Associate Professor, Obstetrics & Gynecology
Office of Women in Medicine and Science

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