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Edward G. Shaw, M.D.Wake Forest School of Medicine

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Edward G. Shaw, M.D.

Professor,





Clinical Specialties

General Radiation Oncology, Radiation Therapy for Brain Tumors and Spinal Cord Tumors in Adults and Children, Radiation-Induced Brain Injury, Radiation Oncology, Gamma Knife

Contact Information

New Patient Appointments: 336-716-WAKE
Returning Patient Appointments: 336-713-3600
Department: 336-713-3600

Email: eshaw@wakehealth.edu

Insurance Accepted »

Education & Training

  • B.S., University of Iowa , 1979
  • M.D., Rush Medical College , 1983
  • Internship, Mayo Clinic, 1984
  • Residency, Mayo Clinic, 1987

Memberships

  • Am Assn Of Sex Educatrs & Coun
  • Am Coll Of Radiology
  • Am Medical Assn
  • Am Soc Of Hospital Pharmacists
  • Am Veterinary Radiological Soc
  • Int'L Soc For Stereotactic Rad
  • Int'L Soc For Study Of Lung Ca

NPI Number

  • 1538141585
Edward G. Shaw, M.D.

Doctor Rating

No Rating Available
Why No Ratings?

Edward G. Shaw, M.D.

Professor, Radiation Oncology
Comprehensive Cancer Center
Brain Tumor Center of Excellence
Sticht Center on Aging
Center for Integrative Medicine
Gerontology and Geriatric Medicine

Research Interests

cancer/oncogenesis, immunology/allergy/inflammatio, neurosciences/behavior, vaccines

Contact Information

Academic: 336-713-3600 | Department: 336-713-3600

Email: eshaw@wakehealth.edu

Recent Publications

Prabhu RS, Won M, Shaw EG, Hu C, Brachman DG, Buckner JC, Stelzer KJ, Barger GR, Brown PD, Gilbert MR, Mehta MP. Effect of the addition of chemotherapy to radiotherapy on cognitive function in patients with low-grade glioma: secondary analysis of RTOG 98-02. J Clin Oncol. 2014;32(6):535-541.

Kilburn JM, Ellis TL [deceased], Lovato JF, Urbanic JJ, Daniel Bourland J, Munley MT, Deguzman AF, McMullen KP, Shaw EG, Tatter SB, Chan MD. Local control and toxicity outcomes in brainstem metastases treated with single fraction radiosurgery: is there a volume threshold for toxicity?. J Neurooncol. 2014;117(1):167-174.

Weller M, Marshall K, Lovato JF, Bourland JD, deGuzman AF, Munley MT, Shaw EG, Tatter SB, Chan MD. Single-institution retrospective series of gamma knife radiosurgery in the treatment of multiple sclerosis-related trigeminal neuralgia: factors that predict efficacy. Stereotact Funct Neurosurg. 2014;92(1):53-58.

Cairncross JG, Wang M, Jenkins RB, Shaw EG, Giannini C, Brachman DG, Buckner JC, Fink KL, Souhami L, Laperriere NJ, Huse JT, Mehta MP, Curran WJ Jr. Benefit from procarbazine, lomustine, and vincristine in oligodendroglial tumors is associated with mutation of IDH. J Clin Oncol. 2014;32(8):783-790.

Hall D, Wilkerson J, Lovato J, Sink K, Chamberlain D, Alli R, Clarke P, Rogers S, Villalba J, Williams J, Shaw EG. Variables associated with high caregiver stress in patients with mild cognitive impairment or Alzheimer's disease: implications for providers in a co-located memory assessment clinic. J Ment Health Couns. 2014;36(2):145-159.

Paulsson AK, McMullen KP, Peiffer AM, Hinson WH, Kearns WT, Johnson AJ, Lesser GJ, Ellis TL, Tatter SB, Debinski W, Shaw EG, Chan MD. Limited margins using modern radiotherapy techniques does not increase marginal failure rate of glioblastoma. Am J Clin Oncol. 2014;37(2):177-181.

Ayala-Peacock DN, Peiffer AM, Lucas JT, Isom S, Kuremsky JG, Urbanic JJ, Bourland JD, Laxton AW, Tatter SB, Shaw EG, Chan MD. A nomogram for predicting distant brain failure in patients treated with gamma knife stereotactic radiosurgery without whole brain radiotherapy. Neuro Oncol. 2014;():.

Cairncross G, Wang M, Shaw E, Jenkins R, Brachman D, Buckner J, Fink K, Souhami L, Laperriere N, Curran W, Mehta M. Phase III trial of chemoradiotherapy for anaplastic oligodendroglioma: long-term results of RTOG 9402. J Clin Oncol. 2013;31(3):337-343.

Peiffer AM, Leyrer CM, Greene-Schloesser DM, Shing E, Kearns WT, Hinson WH, Tatter SB, Ip EH, Rapp SR, Robbins ME [deceased], Shaw EG, Chan MD. Neuroanatomical target theory as a predictive model for radiation-induced cognitive decline. Neurology. 2013;80(8):747-753.

Moore JS, Shaw C, Shaw E, Buechner-Maxwell B, Scarratt WK, Crisman M, Furr M, Robertson J. Melanoma in horses: current perspectives. Equine Vet Educ. 2013;25(3):144-151.

Lesser GJ, Case D, Stark N, Williford S, Giguere J, Garino LA, Naughton MJ, Vitolins MZ, Lively MO, Shaw EG. A randomized, double-blind, placebo-controlled study of oral coenzyme Q10 to relieve self-reported treatment-related fatigue in newly diagnosed patients with breast cancer. J Support Oncol. 2013;11(1):31-42.

Hopewell JW, Bourland JD, Shaw EG. Mike Robbins 1954-2013 [obituary]. Int J Radiat Biol. 2013;89(6):482-483.

Chan MD, Shaw EG, Tatter SB. Radiosurgical management of trigeminal neuralgia. Neurosurg Clin N Am. 2013;24(4):613-621.

Hall D, Wilkerson J, Lovato J, Sink K, Chamberlain D, Clarke P, Villalba J, Alli R, Williams J, Rogers S, Shaw E. Mental health symptoms in people with cognitive impairment and memory loss and their caregivers: initial finding and implications for counselors and geriatricians [abstract]. Alzheimers Dement. 2013;9(4 Suppl):P485-P486.

Sink K, Lovato J, Chamberlain D, Alli R, Clarke P, Hall D, Villalba J, Shaw E. High neuroticism in caregivers is associated with greater burden independent of degree of cognitive impairment or neuropsychiatric symptoms [abstract]. Alzheimers Dement. 2013;9(4 Suppl):P493.

Alli R, Hall D, Clarke P, Hugenschmidt C, Rogers S, Sink K, Villalba J, Williams J, Wilson V, Shaw E. An interdisciplinary counseling center for individuals, couples and families afftected by MCI and dementia [abstract]. Alzheimers Dement. 2013;9(4 Suppl):P646.

Shaw E, Hall D, Lovato J, Alli R, Clarke P, Villalba J, Sink K. Caregiver Burden Scale item analysis: implications for mental health counseling approaches [abstract]. Alzheimers Dement. 2013;9(4 Suppl):P646.

Neth B, Colmer HG IV, Hugenschmidt C, Fitzsimmons S, Shaw E, Alli R, Sun D, Henningsen D, Mugweru J, Sink K. A brain fitness program for people with dementia concurrent with a support group for their caregivers is feasible [abstract]. Alzheimers Dement. 2013;9(4 Suppl):P647-P648.

Clarke PB, Shaw EG, Villalba JA, Alli R, Sink KM. Therapeutic interactions to enhance the mental health and wellness of dementia caregivers and patients. J Gerontol Nurs. 2013;39(11):7-10.

Kuhn E, Taksler GB, Dayton O, Loganathan A, Bourland J, Ellis TL [deceased], Laxton AW, Shaw EG, Chan MD, Tatter SB. Adverse toxicity after stereotactic radiosurgery for treatment of meningiomas [abstract]. Int J Radiat Oncol Biol Phys. 2013;87(2 Suppl):S259.

Randolph D, Peiffer AM, Klepin H, Ayala-Peacock DN, Lester SC, Laxton AW, Tatter SB, Shaw EG, Chan MD. Impact of radiosurgical management of geriatric patients with brain metastases: clinical and quality of life outcomes [abstract]. Int J Radiat Oncol Biol Phys. 2013;87(2 Suppl):S609.

Kuremsky JG, Urbanic JJ, Petty WJ, Lovato JF, Bourland JD, Tatter SB, Ellis TL [deceased], McMullen KP, Shaw EG, Chan MD. Tumor histology predicts patterns of failure and survival in patients with brain metastases from lung cancer treated with gamma knife radiosurgery. Neurosurgery. 2013;73(4):641-647.

Vitolins MZ, Griffin L, Tomlinson WV, Vuky J, Adams PT, Moose D, Frizzell B, Lesser GJ, Naughton M, Radford JE Jr, Shaw EG. Randomized trial to assess the impact of venlafaxine and soy protein on hot flashes and quality of life in men with prostate cancer. J Clin Oncol. 2013;31(32):4092-4098.

Peiffer AM, Burke A, Leyer CM, Shing E, Kearns WT, Hinson WH, Case D, Rapp SR, Shaw EG, Chan MD. Normal tissue complication probability (Ntcp) model of radiation-induced mood disruption [abstract]. Neuro Oncol. 2013;15(Suppl 3):230.

Okada H, Butterfield L, Hamilton R, Drappatz J, Engh J, Amankulor N, Lively M, Chan M, Salazar A, Potter D, Shaw E, Lieberman F. Robust induction of type-1 CD8(+) T-cell responses INWHOgrade II low-grade glioma patients receiving peptide-based vaccines in combination with poly-ICLC [abstract]. Neuro Oncol. 2013;15(Suppl 3):71.

Hopewell JW, Bourland JD, Shaw EG. Michael E. Robbins, Ph.D. 1954-2012 [in memoriam]. Radiat Res. 2013;179(5):615-616.

Shaw EG, Case D, Bryant D, Grisell D, Lesser G, Monitto DC, Naughton MJ, Rapp SR, Sovano SR, Shah S, Chan MD. Phase II double-blind placebo-controlled study of armodafinil for brain radiation induced fatigue [abstract]. J Clin Oncol. 2013;31(15 Suppl):9505.

Urbanic JJ, Case D, Naughton MJ, Hu JJ, Enevold G, Beech B, Weaver KE, Danhauer S, Rapp SR, Sheidler V, Vitolins M, Lesser G, Shaw EG. Minority accrual on a prospective study targeting a diverse US breast cancer population: an analysis of Wake Forest CCOP research base protocol 97609 [abstract]. J Clin Oncol. 2013;31(15 Suppl):6564.

Rapp SR, Case D, Peiffer A, Naughton MJ, Stieber VW, Bayer GK, Bilodeau PA, Moore DF, Falchuk SC, Needles BM , Piephoff J, Edenfield WJ, Giguere JK, Erickson N, Loghin ME, Shaw EG. Phase III randomized, double-blind, placebo-controlled trial of donepezil in irradiated brain tumor survivors [abstract]. J Clin Oncol. 2013;31(15 Suppl):2006.

Case D, Naughton MJ, Stieber VW, Bayer GK, Bilodeau PA, Moore DF, Falchuk SC, Needles BM, Piephoff J, Edenfield WJ, Giguere JK, Erickson N, Loghin ME, Shaw EG, Rapp SR. Quality of life (QOL) and cognitive status among irradiated brain tumor survivors treated with donepezil or placebo [abstract]. J Clin Oncol. 2013;31(15 Suppl):2051.

Neal MT, Chan MD, Lucas JT Jr, Loganathan A, Dillingham C, Pan E, Stewart JH IV, Bourland JD, Shaw EG, Tatter SB, Ellis TL. Predictors of survival, neurologic death, local failure, and distant failure after gamma knife radiosurgery for melanoma brain metastases. World Neurosurg. 2013;():.

Monjazeb AM, Ayala D, Jensen C, Case LD, Bourland JD, Ellis TL, McMullen KP, Chan MD, Tatter SB, Lesser GJ, Shaw EG. A phase I dose escalation study of hypofractionated IMRT field-in-field boost for newly diagnosed glioblastoma multiforme. Int J Radiat Oncol Biol Phys. 2012;82(2):743-748.

Ruiz J, Case D, Enevold G, Rosdhal R, Tatter SB, Ellis TL, McQuellon RP, McMullen KP, Stieber VW, Shaw EG, Lesser GJ. A phase II trial of thalidomide and procarbazine in adult patients with recurrent or progressive malignant gliomas. J Neurooncol. 2012;106(3):611-617.

Marshall K, Chan MD, McCoy TP, Aubuchon AC, Bourland JD, McMullen KP, deGuzman AF, Munley MT, Shaw EG, Tatter SB, Ellis TL. Predictive variables for the successful treatment of trigeminal neuralgia with gamma knife radiosurgery. Neurosurgery. 2012;70(3):566-573.

Harris S, Chan MD, Lovato JF, Ellis TL, Tatter SB, Bourland JD, Munley MT, deGuzman AF, Shaw EG, Urbanic JJ, McMullen KP. Gamma knife stereotactic radiosurgery as salvage therapy after failure of whole-brain radiotherapy in patients with small-cell lung cancer. Int J Radiat Oncol Biol Phys. 2012;83(1):e53-e59.

Cochran DC, Chan MD, Aklilu M, Lovato JF, Alphonse NK, Bourland JD, Urbanic JJ, McMullen KP, Shaw EG, Tatter SB, Ellis TL. The effect of targeted agents on outcomes in patients with brain metastases from renal cell carcinoma treated with Gamma Knife surgery. J Neurosurg. 2012;116(5):978-983.

Attia A, Chan MD, Mott RT, Russell GB, Seif D, Bourland JD, Deguzman AF, Ellis TL, McMullen KP, Munley MT, Tatter SB, Shaw EG. Patterns of failure after treatment of atypical meningioma with gamma knife radiosurgery. J Neurooncol. 2012;108(1):179-185.

Sams K, Case LD, Lesser GJ, Naughton MJ, Williford SK, Giguere JK, Garino A, Vitolins M, Shaw EG. Comparing three validated methods of patient self-reported fatigue in a prospective randomized clinical trial [abstract]. J Clin Oncol. 2012;30(15 Suppl):Abstr 9108.

Attia A, Rapp SR, Case LD, D'Agostino R, Lesser G, Naughton M, McMullen K, Rosdhal R, Shaw EG. Phase II study of Ginkgo biloba in irradiated brain tumor patients: effect on cognitive function, quality of life, and mood. J Neurooncol. 2012;109(2):357-363.

High KP, Case D, Hurd D, Powell B, Lesser G, Falsey AR, Siegel R, Metzner-Sadurski J, Krauss JC, Chinnasami B, Sanders G, Rousey S, Shaw EG. A randomized, controlled trial of Panax quinquefolius extract (CVT-E002) to reduce respiratory infection in patients with chronic lymphocytic leukemia. J Support Oncol. 2012;10(5):195-201.

Attia A, Tatter SB, Weller M, Marshall K, Lovato JF, Bourland JD, Ellis TL [deceased], McMullen KP, Shaw EG, Chan MD. CT-only planning for Gamma Knife radiosurgery in the treatment of trigeminal neuralgia: methodology and outcomes from a single institution. J Med Imaging Radiat Oncol. 2012;56(4):490-494.

Castellino SM, Tooze JA, Flowers L, Hill DF, McMullen KP, Shaw EG, Parsons SK. Toxicity and efficacy of the acetylcholinesterase (AChe) inhibitor donepezil in childhood brain tumor survivors: a pilot study. Pediatr Blood Cancer. 2012;59(3):540-547.

Greene-Schloesser D, Robbins ME, Peiffer AM, Shaw EG, Wheeler KT, Chan MD. Radiation-induced brain injury: a review. Front Oncol. 2012;2():73.

Amponsah K, Ellis TL [deceased], Chan MD, Lovato JF, Bourland JD, deGuzman AF, Ekstrand KE, Munley MT, McMullen KP, Shaw EG, Tatter SB. Retrospective analysis of imaging techniques for treatment planning and monitoring of obliteration for gamma knife treatment of cerebral arteriovenous malformation. Neurosurgery. 2012;71(4):893-900.

Squire SE, Chan MD, Furr RM, Lowell DA, Tatter SB, Ellis TL [deceased], Bourland JD, Deguzman AF, Munley MT, Ekstrand KE, Shaw EG, McMullen KP. Gamma knife radiosurgery in the treatment of tumor-related facial pain. Stereotact Funct Neurosurg. 2012;90(3):145-150.

Shaw EG, Wang M, Coons SW, Brachman DG, Buckner JC, Stelzer KJ, Barger GR, Brown PD, Gilbert MR, Mehta MP. Randomized trial of radiation therapy plus procarbazine, lomustine, and vincristine chemotherapy for supratentorial adult low-grade glioma: initial results of RTOG 9802. J Clin Oncol. 2012;30(25):3065-3070.

Vern-Gross TZ, Lawrence JA, Case LD, McMullen KP, Bourland JD, Metheny-Barlow LJ, Ellis TL [deceased], Tatter SB, Shaw EG, Urbanic JJ, Chan MD. Breast cancer subtype affects patterns of failure of brain metastases after treatment with stereotactic radiosurgery. J Neurooncol. 2012;110(3):381-388.

Loganathan AG, Chan MD, Alphonse N, Peiffer AM, Johnson AJ, McMullen KP, Urbanic JJ, Saconn PA, Bourland JD, Munley MT, Shaw EG, Tatter SB, Ellis TL [deceased]. Clinical outcomes of brain metastases treated with Gamma Knife radiosurgery with 3.0T versus 1.5T MRI-based treatment planning: have we finally optimised detection of occult brain metastases?. J Med Imaging Radiat Oncol. 2012;56(5):554-560.

Ayala-Peacock D, Peiffer AM, Ellis TL [deceased], Tatter SB, Urbanic JJ, Bourland JD, Shaw EG, Chan MC. Predictive factors for distant brain failure after primary radiosurgical management of brain metastases [abstract]. Int J Radiat Oncol Biol Phys. 2012;84(3 Suppl):S296.

Cairncross G, Wang M, Jenkins R, Shaw E, Giannini C, Brachman D, Buckner J, Fink K, Mehta M, Curran W. IDH status predicts benefit from PCV with radiation therapy in anaplastic oligodendroglioma (RTOG 9402) [abstract]. Int J Radiat Oncol Biol Phys. 2012;84(3 Suppl):S5.

Lucas J, Marshall K, Bourland D, Shaw E, Ellis T [deceased], Tatter S, Chan MD. Predictors of durability of response for stereotactic radiosurgery in the treatment of trigeminal neuralgia [abstract]. Int J Radiat Oncol Biol Phys. 2012;84(3 Suppl):S37-S38.

Okada H, Butterfield LH, Hamilton RL, Lively MO, Chan MD, Salazar AM, Potter DM, Shaw EG, Lieberman FS. A BI-institutional pilot study of peptide-based vaccines in combination with poly ICLC in patients with WHO grade 2 low-grade glioma [abstract]. J Immunother. 2012;35(9):743.

Okada H, Butterfield LH, Hamilton RH, Mintz AH, Engh JA, Drappatz J, Lively MO, Chan MD, Salazar AM, Potter DM, Shaw EG, Liebeman FS. A BI-institutional pilot study of peptide-based vaccines in combination with poly ICLC in patients with WHO grade 2 low-grade glioma [abstract]. Neuro Oncol. 2012;14(Suppl 6):44.

Paulsson A, Peiffer AM, McMullen KP, Hinson WH, Lesser GJ, Ellis TL [deceased], Tatter SB, Shaw EG, Chan MD. Comparison of clinical outcomes for single focus and multifocal glioblastoma [abstract]. Int J Radiat Oncol Biol Phys. 2012;84(3 Suppl):S274.

Peiffer AM, Case D, Shaw EG, Rapp S. Magnetic resonance imaging associates with differences in neurocognitive performance for cancer survivors complaining of cognitive deficits following brain irradiation [abstract]. Neuro Oncol. 2012;14(Suppl 6):63.

Jensen CA, Chan MD, McCoy TP, Bourland JD, deGuzman AF, Ellis TL, Ekstrand KE, McMullen KP, Munley MT, Shaw EG, Urbanic JJ, Tatter SB. Cavity-directed radiosurgery as adjuvant therapy after resection of a brain metastasis. J Neurosurg. 2011;114(6):1585-1591.

Chan MD, Attia A, Tatter SB, Lesser G, Zapadka ME, Mott RT, Carter A, McMullen KP, Shaw EG, Ellis TE [sic ] [Ellis TL]. Radiation-induced adult medulloblastoma: a two-case report and review of the literature. J Neurooncol. 2011;103(3):745-749.

Daniels TB, Brown PD, Felten SJ, Wu W, Buckner JC, Arusell RM, Curran WJ, Abrams RA, Schiff D, Shaw EG. Validation of EORTC prognostic factors for adults with low-grade glioma: a report using intergroup 86-72-51. Int J Radiat Oncol Biol Phys. 2011;81(1):218-224.

Aubuchon AC, Chan MD, Lovato JF, Balamucki CJ, Ellis TL, Tatter SB, McMullen KP, Munley MT, Deguzman AF, Ekstrand KE, Bourland JD, Shaw EG. Repeat gamma knife radiosurgery for trigeminal neuralgia. Int J Radiat Oncol Biol Phys. 2011;81(4):1059-1065.

Lowell D, Tatter SB, Bourland JD, DeGuzman AF, Ekstrand KE, Ellis TL, Lovato JF, McMullen KP, Munley MT, Shaw EG, Urbanic JJ, Chan MD. Toxicity of gamma knife radiosurgery in the treatment of intracranial tumors in patients with collagen vascular diseases or multiple sclerosis. Int J Radiat Oncol Biol Phys. 2011;81(4):e519-e524.

Amponsah K, Ellis TL, Chan MD, Bourland JD, Glazier SS, McMullen KP, Shaw EG, Tatter SB. Staged gamma knife radiosurgery for large cerebral arteriovenous malformations. Stereotact Funct Neurosurg. 2011;89(6):365-371.

Kilburn JM, Ellis TL, Urbanic JJ, Bourland JD, Munley MT, deGuzman AF, McMullen KP, Shaw EG, Tatter SB, Chan MD. Outcomes for gamma knife radiosurgery for brainstem metastases [abstract]. Int J Radiat Oncol Biol Phys. 2011;81(2 Suppl):S302.

Kuremsky JG, Urbanic JJ, Petty WJ, Lovato JF, Bourland JD, Tatter SB, Ellis TL, McMullen KP, Shaw EG, Chan MD. Tumor histology predicts patterns of failure and survival in patients with lung cancer treated with gamma knife radiosurgery [abstract]. Int J Radiat Oncol Biol Phys. 2011;81(2 Suppl):S595.

Leyrer CM, Peiffer AM, Greene-Schloesser DM, Kearns WT, Hinson WH, Tatter SB, Rapp SR, Robbins ME, Shaw EG, Chan MD. Normal tissue complication modeling of the brain: dose-volume histogram analysis of neurocognitive outcomes of two CCOP trials [abstract]. Int J Radiat Oncol Biol Phys. 2011;81(2 Suppl):S184-S185.

Li J, Wang M, Won M, Shaw EG, Coughlin C, Curran WJ Jr, Mehta MP. Validation and simplification of the Radiation Therapy Oncology Group recursive partitioning analysis classification for glioblastoma. Int J Radiat Oncol Biol Phys. 2011;81(3):623-630.

Loganathan AG, Chan MD, Alphonse N, Peiffer AM, Johnson A, McMullen KP, Urbanic JJ, Saconn PA, Bourland JD, Munley MT, Shaw EG, Tatter SB, Ellis TL. Clinical outcomes of brain metastases treated with gamma knife radiosurgery with 3.0 T vs. 1.5 T MRI-based treatment planning [abstract]. Neuro Oncol. 2011;13(Suppl 3):129.

Paulsson AK, Chan MD, Peiffer AM, Hinson WH, Kearns WT, Lesser GJ, Ellis TL, Tatter SB, Shaw EG, McMullen KP. Decreased CTV margin size does not affect patterns of failure for glioblastoma treated with concurrent radiotherapy and temozolomide [abstract]. Int J Radiat Oncol Biol Phys. 2011;81(2 Suppl):S183.

Peiffer AM, Leyrer CM, Greene-Schloesser D, Kearns WT, Hinson WH, Tatter SB, Rapp SR, Robbins ME, Shaw EG, Chan MD. Normal tissue complication modeling of the brain: dose-volume histogram analysis of neurocognitive outcomes of two CCOP trials [abstract]. Neuro Oncol. 2011;13(Suppl 3):73.

Vern-Gross TZ, McMullen KP, Case LD, Bourland JD, Ellis TL, Lawrence JA, Tatter SB, Shaw EG, Urbanic JJ, Chan MD. Patterns of failure in patients receiving gamma knife radiosurgery for breast carcinoma to the brain [abstract]. Int J Radiat Oncol Biol Phys. 2011;81(2 Suppl):S216-S217.

Vern-Gross TZ, McMullen KP, Case LD, Bourland JD, Ellis TL, Lawrence JA, Tatter SB, Shaw EG, Urbanic JJ, Chan MD. Patterns of failure in patients receiving gamma knife radiosurgery for breast carcinoma to the brain [abstract]. Neuro Oncol. 2011;13(Suppl 3):127.

Attia A, Case LD, D'Agostino R Jr, Lesser GJ, McMullen K, Naughton MJ, Rapp SR, Rosdhal R, Shaw EG. Phase II study of ginkgo biloba in irradiated brain tumor survivors: effects on quality of life (QOL), mood, and cognitive function [abstract]. J Clin Oncol. 2010;28(Suppl):e12523.

Rapp SR, Case LD, Loghin ME, Meyers CA, Saphner TJ, Sleckman BG, Stieber VW, Atkins JN, Giguere JK, Shaw EG. Correlation of cognitive symptoms with cognitive performance among brain cancer patients after radiation therapy [abstract]. J Clin Oncol. 2010;28(Suppl 7):abstr 2084.

Case LD, Naughton MJ, Lesser GJ, Rapp SR, Vitolins M, Sheidler VR, Enevold GL, Shaw EG. Recruitment and retention in the Wake Forest University CCOP Research Base [abstract]. J Clin Oncol. 2010;28(Suppl):e19543.

Naughton MJ, Case LD, Meyers CA, Loghin ME, Shaw EG, Saphner TJ, Sleckman BG, Giguere JK, Lesser GJ, Rapp SR. Quality of life (QOL) and cognitive performance among irradiated brain cancer patients [abstract]. J Clin Oncol. 2010;28(Suppl 7):abstr 9131.

Lesser GJ, Case LD, Stark N, Williford SK, Giguere JK, Garino A, Naughton MJ, Vitolins M, Lively M, Shaw EG. A randomized double-blind placebo-controlled study of oral coenzyme Q10 to relieve self-reported cancer-treatment-related fatigue in newly diagnosed breast cancer patients [abstract]. J Clin Oncol. 2010;28(15 Suppl):9006.

Vitolins M, Lesser GJ, Case LD, Williford SK, Giguere JK, Garino A, Naughton MJ, Lively M, Melin SA, Shaw EG. Self-reported compliance compared to biomarker levels of vitamin E in breast cancer patients participating in a CoQ10 clinical trial [abstract]. J Clin Oncol. 2010;28(15 Suppl):e19524.

High KP, Case LD, Siegel RD, Metzner-Sidurski J, Krauss JC, Chinnasami B, Sanders GH, Rousey S, Lesser GJ, Shaw EG. A phase III randomized, double-blind, placebo controlled trial of North American (NA) ginseng (Panax quinquefolium) extract (CVT-E002) in patients with chronic lymphocytic leukemia: effect on respiratory infection and antibiotic use [abstract]. J Clin Oncol. 2010;28(15 Suppl):6578.

Wang M, Cairncross G, Shaw E, Jenkins R, Scheithauer B, Brachman D, Buckner J, Fink K, Souhami L, Laperriere N, et al. Cognition and quality of life after chemotherapy plus radiotherapy (RT) vs. RT for pure and mixed anaplastic oligodendrogliomas: radiation therapy oncology group trial 9402. Int J Radiat Oncol Biol Phys. 2010;77(3):662-669.

Chan MD, Tatter SB, Lesser G, Shaw EG. Radiation oncology in brain tumors: current approaches and clinical trials in progress. Neuroimaging Clin N Am. 2010;20(3):401-408.

Saconn PA, Shaw EG, Chan MD, Squire SE, Johnson AJ, McMullen KP, Tatter SB, Ellis TL, Lovato J, Bourland JD, Ekstrand KE, DeGuzman AF, Munley MT. Use of 3.0-T MRI for stereotactic radiosurgery planning for treatment of brain metastases: a single-institution retrospective review. Int J Radiat Oncol Biol Phys. 2010;78(4):1142-1146.

Lowell DA, Shaw EG, Bourland JD, de Guzman AF, Ekstrand KE, Ellis TL, McMullen KP, Munley MT, Tatter SB, Chan MD. Analysis of toxicity in patients with collagen vascular diseases or multiple sclerosis treated with gamma knife radiosurgery for intracranial tumors [abstract]. Int J Radiat Oncol Biol Phys. 2010;78(3 Suppl):S269-S270.

Marshall KM, Chan MD, Ellis TL, Aubuchon A, Balamucki CJ, Bourland JD, McCoy TP, McMullen KP, Shaw EG, Tatter SB. Predictive variables for successful treatment of trigeminal neuralgia with radiosurgery [abstract]. Int J Radiat Oncol Biol Phys. 2010;78(3 Suppl):S8.

McMullen KP, Harris S, Lovato J, Ellis TL, Tatter SB, Urbanic J, Bourland JD, Shaw EG, Chan MD. Salvage radiosurgery for patients with small cell lung cancer after previous whole brain radiations [abstract]. Int J Radiat Oncol Biol Phys. 2010;78(3 Suppl):S274-S275.

Lawrence MV, Rossi P, Powell D, Ekstrand KE, deGuzman AF, Munley MT, Ellis TL, Tatter SB, Stieber VW, McMullen KP, Shaw EG, Bourland JD.Relationship between radiosurgery conformity indices and acoustic neuroma tumor volume

Wentworth S, Pinn M, Bourland JD, DeGuzman AF, Ekstrand K, Ellis TL, Glazier SS, McMullen KP, Munley M, Stieber VW, Tatter SB, Shaw EG. Clinical experience with radiation therapy in the management of neurofibromatosis-associated central nervous system tumors. Int J Radiat Oncol Biol Phys. 2009;73(1):208-213.

Bauman GS, Shaw EG, Cha S, Barani IJ, McDermott M. Some like it hot ... and others not! [editorial]. Int J Radiat Oncol Biol Phys. 2009;74(5):1319-1322.

Hochberg FH, Rodriguez FJ, Atkinson JLD, Shaw EG, Keegan BM, Kantarci OH. A 54-year-old woman with progressive gait disturbance and MRI abnormalities. Neurology. 2009;73(6):466-474.

Schomas DA, Laack NNI, Rao RD, Meyer FB, Shaw EG, O'Neill BP, Giannini C, Brown PD. Intracranial low-grade gliomas in adults: 30-year experience with long-term follow-up at Mayo Clinic. Neuro Oncol. 2009;11(4):437-445.

Attia A, Chan M, Seif D, Russell GB, Bourland JD, Deguzman A, Ellis T, McMullen K, Tatter S, Shaw EG. Treatment of atypical meningiomas with gamma knife radiosurgery: the role of conformality index and margin dose [abstract]. Int J Radiat Oncol Biol Phys. 2009;75(3 Suppl 1):S226-S227.

Aubuchon AC, Chan M, Lovano J, McMullen K, Ellis T, Tatter S, Bourland J, Deguzman A, Munley M, Shaw E. Dorsal root entry zone dose predicts efficacy and toxicity for patients receiving a second radiosurgical treatment for recurrent trigeminal neuralgia [abstract]. Int J Radiat Oncol Biol Phys. 2009;75(3 Suppl 1):S240.

Jensen CA, Chan MD, McCoy TP, Shaw EG, McMullen KP, Ellis TL, Munley MT, Bourland JD, De Guzman AF, Tatter SB. Adjuvant radiosurgery after resection of a brain metastasis allows for the delay or elimination of whole brain radiotherapy [abstract]. Int J Radiat Oncol Biol Phys. 2009;75(3 Suppl 1):S226.

Wang M, Cairncross G, Shaw E, Jenkins R, Scheithauer B, Brachman D, Buckner J, Souhami L, Laperriere N, Mehta M, et al. Cognition and quality of life after chemotherapy plus radiotherapy (RT) vs. RT for pure and mixed anaplastic oligodendrogliomas: Radiation Therapy Oncology Group trial 940 [abstract]. J Clin Oncol. 2009;27(15 Suppl):e20519.

Demark-Wahnefried W, Case LD, Blackwell K, Marcom PK, Kraus W, Aziz N, Snyder DC, Giguere JK, Shaw E. Results of a diet/exercise feasibility trial to prevent adverse body composition change in breast cancer patients on adjuvant chemotherapy. Clin Breast Cancer. 2008;8(1):70-79.

Spillman WB Jr, Robertson JL, Meissner KE, Jesselli J, Bourland JD, Robbins ME, Shaw EG. Shape factor analysis of progressive rat hepatoma images. J Biomed Opt. 2008;13(1):art.014030.


Rijmen F, Ip EH, Rapp S, Shaw EG. Qualitative longitudinal analysis of symptoms in patients with primary and metastatic brain tumours. J R Stat Soc Ser A Stat Soc. 2008;171(Pt 3):739-753.

Cairncross G, Wang M, Chang S, Shaw E, Jenkins R, Scheithauer B, Buckner J, Fink K, Mehta M, Curran W. A randomized trial or chemotherapy plus radiotherapy (RT) versus RT alone for anaplastic oligodendroglioma (RTOG 9402): the perspective of longer follow-up [abstract]. Int J Radiat Oncol Biol Phys. 2008;72(1 Suppl):S7-S8.

Monjazeb AM, Bourland JD, Case LD, Ellis TL, Lesser GJ, McMullen KP, Munley M, Tatter SB, Shaw EG. A phase I dose escalation study of IMRT field-in-field boost for newly diagnosed glioblastoma multiforme (GBM) [abstract]. Int J Radiat Oncol Biol Phys. 2008;72(1 Suppl 1):S227.

Squire SE, Ellis TL, Shaw EG, Tatter SB, McMullen KP. Tumor-related facial pain: response to gamma knife radiosurgery [abstract]. Int J Radiat Oncol Biol Phys. 2008;72(1 Suppl):S225.

Shaw EG, Berkey B, Coons SW, Bullard D, Brachman D, Buckner JC, Stelzer KJ, Barger GR, Brown PD, Gilbert MR, et al. Recurrence following neurosurgeon-determined gross-total resection of adult supratentorial low-grade glioma: results of a prospective clinical trial. J Neurosurg. 2008;109(5):835-841.

Shaw E, Wang MH, Coons SW, Brachman D, Buckner L, Stelzer K, Barger G, Brown P, Gilbert MR, Mehta M. Radiation therapy (RT) versus RT plus procarbazine, CCNU, and vincristine (PCV) chemotherapy for adult low-grade glioma (LGG): Radiation Therapy Oncology Group (RTOG) Protocol 9802 [abstract]. Neuro Oncol. 2008;10(5):884-885.

Squire S, Center B, Ellis T, Shaw E, Tatter S, McMullen K. Gamma knife stereotactic radiosurgery for brain metastases: timing of posttreatment MRI [abstract]. Neuro Oncol. 2008;10(5):889.

Lesser GJ, Case D, Ottery F, McQuellon R, Choksi JK, Sanders G, Rosdhal R, Shaw EG. A phase III randomized study comparing the effects of oxandrolone (Ox) and megestrol acetate (Meg) on lean body mass (LBM), weight (wt) and quality of life (QOL) in patients with solid tumors and weight loss receiving chemotherapy [abstract]. J Clin Oncol. 2008;26(15 Suppl Pt I):505s.

Gunderson LL, Tepper JE, Ang KK, Choy H, Harris JR, Kun LE, Mauch P, Shaw EG, Thomas GM, Zietman AL. In: Clinical radiation oncology. 2nd ed. Philadelphia: Elsevier Churchill Livingstone;2007: .

Shaw EG, Debinski W, Robbins ME. Central nervous system tumors: overview In: Gunderson LL, Tepper JE, eds. Clinical radiation oncology. 2nd ed. Philadelphia: Elsevier Churchill Livingstone;2007: 459-492.

Brown PD, Shaw EG. Low-grade gliomas In: Gunderson LL, Tepper JE, eds. Clinical radiation oncology. 2nd ed. Philadelphia: Elsevier Churchill Livingstone;2007: 493-514.

Bauman G, Fisher B, Schild S, Shaw EG. Meningioma, ependymoma, and other adult brain tumors In: Gunderson LL, Tepper JE, eds. Clinical radiation oncology. 2nd ed. Philadelphia: Elsevier Churchill Livingstone;2007: 539-566.

Stieber VW, Shaw EG. Spinal cord tumors In: Gunderson LL, Tepper JE, eds. Clinical radiation oncology. 2nd ed. Philadelphia: Elsevier Churchill Livingstone;2007: 591-612.

Lesser GJ, Stieber V, Case D, Enevold G, Rosdhal R, Tatter S, Ellis T, McMullen K, Shaw E. A phase II trial of thalidomide (Thal) and procarbazine (Pro) in adults with recurrent or progressive malignant gliomas (MG) [abstract]. J Clin Oncol. 2007;25(18 Suppl Pt I):91s.


Stieber V, Robbins M, deGuzman A, Tatter S, Ekstrand K, McMullen K, Branch C, Shaw E, Bourland JD, Lovato J, Munley M, Ellis T, et al. Determination of a clinical value for the repair half-time (T1/2) of the trigeminal nerve based on outcome data from gamma knife radiosurgery for facial pain. Radiat Res. 2007;168(2):143-148.

Gleason JF Jr, Case D, Rapp SR, Ip E, Naughton M, Butler JM Jr, McMullen K, Stieber V, Saconn P, Shaw EG. Symptom clusters in patients with newly-diagnosed brain tumors. J Support Oncol. 2007;5(9):427-33,436.

Sloan JA, Berk L, Roscoe J, Fisch MJ, Shaw EG, Wyatt G, Morrow GR, Dueck AC. Integrating patient-reported outcomes into cancer symptom management clinical trials supported by the National Cancer Institute-sponsored clinical trials networks. J Clin Oncol. 2007;25(32):5070-5077.

Wagner LI, Wenzel L, Shaw E, Cella D. Patient-reported outcomes in phase II cancer clinical trials: lessons learned and future directions. J Clin Oncol. 2007;25(32):5058-5062.

Pinn M, Bourland JD, Ellis T, Deguzman A, Ekstrand K, McMullen K, Glazier S, Munley M, Stieber V, Tatter S, Shaw E, et al. Results of stereotactic radiosurgery for NF2 patients with acoustic neuroma [abstract]. Neuro Oncol. 2007;9(4):587.

Wentworth S, Ellis T, Glazier S, McMullen K, Stieber V, Tatter S, Shaw E. Clinical experience with radiation therapy in the management of neurofibromatosis-associated central nervous system tumors [abstract]. Neuro Oncol. 2007;9(4):581.

Butler JM Jr, Case LD, Frizzell B, Lesser G, McMullen K, McQuellon R, Naughton M, Rapp S, Stieber V, Shaw EG, et al. A phase III, double-blind, placebo-controlled prospective randomized clinical trial of d-threo-methylphenidate HCl in brain tumor patients receiving radiation therapy. Int J Radiat Oncol Biol Phys. 2007;69(5):1496-1501.

Lally BE, Shaw EG, Knisely JPS, Blackstock AW, Robbins MC, Geiger AM. Low grade gliomas: demographic, tumor and treatment factors associated with survival [abstract]. Int J Radiat Oncol Biol Phys. 2007;69(3 Suppl):S185.

Wentworth S, Ellis TL, Glazier S, McMullen KP, Stieber VW, Tatter SB, Shaw EG. Clinical experience with radiation therapy in the management of neurofibromatosis-associated central nervous system tumors [abstract]. Int J Radiat Oncol Biol Phys. 2007;69(3 Suppl):S248-S249.

Cairncross G, Berkey B, Shaw E, Jenkins R, Scheithauer B, Brachman D, Buckner J, Fink K, Souhami L, Laperierre N, et al. Phase III trial of chemotherapy plus radiotherapy compared with radiotherapy alone for pure and mixed anaplastic oligodendroglioma: Intergroup Radiation Therapy Oncology Group Trial 9402. J Clin Oncol. 2006;24(18):2707-2714.

Stea B, Shaw E, Pinter T, Hackman J, Craig M, May J, Steffen RP, Suh JH. Efaproxiral red blood cell concentration predicts efficacy in patients with brain metastases. Br J Cancer. 2006;94(12):1777-1784.

Rogers LR, Rock JP, Sills AK, Vogelbaum MA, Suh JH, Ellis TL, Stieber VW, Asher AL, Fraser RW, Shaw EG, et cl. Results of a phase II trial of the GliaSite Radiation Therapy System for the treatment of newly diagnosed, resected single brain metastases. J Neurosurg. 2006;105(3):375-384.

Bourland J, Flowers K, Huey K, Shaw E. Dedicated PET-CT and MR-simulators in a state-of-the-art radiation treatment facility [abstract]. Med Phys. 2006;33(6):2165.

Butler JM, Rapp SR, Shaw EG. Managing the cognitive effects of brain tumor radiation therapy. Curr Treat Options Oncol. 2006;7(6):517-523.

Jenkins RB, Blair H, Ballman KV, Giannini C, Arusell RM, Law M, Flynn H, Passe S, Felten S, Shaw EG, et al. A t(1;19)(q10;p10) mediates the combined deletions of 1p and 19q and predicts a better prognosis of patients with oligodendroglioma. Cancer Res. 2006;66(20):9852-9861.

Kantarci OH, Daugherty WP, Rodriguez FJ, Shaw EG, Parisi JE, Atkinson JL, Lucchinetti CF. Primary amyloidoma of the brain treated with radiation therapy [abstract]. Brain Pathol. 2006;16(Suppl 1):S116.

Balamucki CJ, Stieber VW, Ellis TL, Tatter SB, DeGuzman AF, McMullen KP, Lovato J, Shaw EG, Ekstrand KE, Bourland JD, Munley MT, Robbins M, Branch C. Does dose rate affect efficacy? The outcomes of 256 gamma knife surgery procedures for trigeminal neuralgia and other types of facial pain as they relate to the half-life of cobalt. J Neurosurg. 2006;105(5):730-735.

Jenkins RB, Ballman KV, Giannini C, Arusell RM, Blair H, Passe S, Flynn H, Brown P, Shaw EG, Buckner JC. Diagnostic and prognostic significance of a t(1;19)(ql0;pl0) in patients (pts) with low-grade oligodendrogliama and astrocytoma: NCCTG 94-72-53 [abstract]. J Clin Oncol. 2006;24(18 Suppl Pt I):59s.

Shaw EG, Berkey B, Coons SW, Brachman D, Buckner JC, Stelzer KJ, Barger GR, Brown PD, Gilbert MR, Mehta M. Initial report of Radiation Therapy Oncology Group (RTOG) 9802: prospective studies in adult low-grade glioma (LGG) [abstract]. J Clin Oncol. 2006;24(18 Suppl Pt I):58s.

Kim PK, Ellis TL, Stieber VW, McMullen KP, Shaw EG, McCoy TP, D'Agostino RB, Bourland JD, Deguzman AF, Ekstrand KE, Raber MR, Tatter SB. Gamma Knife surgery targeting the resection cavity of brain metastasis that has progressed after whole-brain radiotherapy. J Neurosurg. 2006;105(Suppl):75-78.

Daniels TB, Brown PD, Ballman K, Felton S, Buckner J, Arusell RM, Curran WJ, Earle JD, Shaw EG. Validation of EORTC prognostic factors for adults with low grade glioma: a report utilizing intergroup 86-72-51 [abstract]. Int J Radiat Oncol Biol Phys. 2006;66(3 Suppl):S83.

McMullen KP, Papagikos MA, Glazier SS, McLean TW, Maldjian JA, Shaw EG. Pseudo-progression based on MRI changes following radiation therapy for pilocytic astrocytoma [abstract]. Int J Radiat Oncol Biol Phys. 2006;66(3 Suppl):S243-S244.

Papagikos MA, McMullen KP, Glazier SS, McLean TW, Maldjian JA, Shaw EG. MRI pseudo-progression following radiation therapy for pilocytic astroctyoma [abstract]. Neuro Oncol. 2006;8(4):487-488.

Shaw EG, Berkey B, Coons SW, Brachman D, Buckner JC, Stelzer KJ, Barger GR, Brown PD, Gilbert MR, Mehta M. Update of an RTOG prospective study of observation in completely resected adult low-grade glioma [abstract]. Neuro Oncol. 2006;8(4):452.

Shaw EG, Berkey B, Coons SW, Brachman D, Buckner JC, Stelzer KJ, Barger GR, Brown PD, Gilbert MR, Mehta M. Radiation therapy oncology group (RTOG) protocol 9802: radiation therapy (RT) alone versus RT plus PCV chemotherapy in adult lowgrade glioma (LGG) [abstract]. Neuro Oncol. 2006;8(4):489-490.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Professor, Radiation Oncology

Clinical Specialties

General Radiation Oncology, Radiation Therapy for Brain Tumors and Spinal Cord Tumors in Adults and Children, Radiation-Induced Brain Injury, Radiation Oncology, Gamma Knife

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