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Thomas D. Shupe, Ph.D.Wake Forest School of Medicine

Thomas D. Shupe, Ph.D.

Assistant Professor,

Contact Information

Academic: 336-713-1212 | Department: 336-713-1212

Email: tshupe@wakehealth.edu

Education & Training

  • B.S., University of Maryland-Baltimore, 1994
  • M.S., Albany Medical College, 1999

Memberships

  • Am Assn for Cancer Research
Thomas D. Shupe, Ph.D.

Thomas D. Shupe, Ph.D.

Assistant Professor, Institute for Regenerative Medicine

Research Interests

Liver; Stem Cells; Carcinoma, Hepatocellular; Liver Neoplasms; Stem Cell Transplantation
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Contact Information

Academic: 336-713-1212 | Department: 336-713-1212

Email: tshupe@wakehealth.edu

Recent Publications

A liver-on-a-chip platform with bioprinted hepatic spheroids. Bhise NS, Manoharan V, Massa S, Tamayol A, Ghaderi M, Miscuglio M, Lang Q, Shrike Zhang Y, Shin SR, Calzone G, Annabi N, Shupe TD, Bishop CE, Atala A, Dokmeci MR, Khademhosseini A.. Biofabrication. 2016;8(1):014101.

Bioprinting cellularized constructs using a tissue-specific hydrogel bioink [video article]. Skardal A, Devarasetty M, Kang HW, Seol YJ, Forsythe SD, Bishop C, Shupe T, Soker S, Atala A.. J Vis Exp. 2016;(110):.

Bioengineered transplantable porcine livers with re-endothelialized vasculature. Ko IK, Peng L, Peloso A, Smith CJ, Dhal A, Deegan DB, Zimmerman C, Clouse C, Zhao W, Shupe TD, Soker S, Yoo JJ, Atala A.. Biomaterials. 2015;40():72-79.

Liver regeneration: a consequence of complex, well-orchestrated signals [commentary]. Shupe TD, Petersen BE.. Hepatology. 2015;62(2):644-645.

A hydrogel bioink toolkit for mimicking native tissue biochemical and mechanical properties in bioprinted tissue constructs. Skardal A, Devarasetty M, Kang HW, Mead I, Bishop C, Shupe T, Lee SJ, Jackson J, Yoo J, Soker S, Atala A.. Acta Biomater. 2015;25():24-34.

Implantation of re-endothelialized porcine liver constructs for whole organ engineering [abstract]. Ko I, Li P, Pelso A, Smith C, Dhal A, Clouse C, Zhao W, Shupe T, Soker S, Yoo JJ, Atala A.. Tissue Eng Part A. 2015;21(Suppl 1):S85.

3-D bioprinting of tissue organoids for body-on-a-chip drug screening platform [abstract]. Seol Y, Kang H, Lee S, Jackson JD, Skardal A, Shupe T, Soker S, Bishop C, Yoo JJ, Atala A.. Tissue Eng Part A. 2015;21(Suppl 1):S369.

A hydrogel bioink toolkit for bioprinting tissue constructs while mimicking native tissue biochemical and mechanical properties [abstract]. Skardal A, Devarasetty M, Kang H, Mead I, Bishop C, Shupe T, Lee S, Jackson J, Yoo J, Soker S, Atala A.. Tissue Eng Part A. 2015;21(Suppl 1):S212.

Physiologically relevant drug testing in vitro - an integrated multiple organoid-on-a-chip approach [abstract]. Skardal A, Kleensang A, Devarasetty M, Kang H, Mead I, Bishop C, Shupe T, Lee S, Jackson J, Yoo J, Hartung T, Soker S, Atala A.. Tissue Eng Part A. 2015;21(Suppl 1):S362.

Stiffness of hyaluronic acid gels containing liver extracellular matrix supports human hepatocyte function and alters cell morphology. Deegan DB, Zimmerman C, Skardal A, Atala A, Shupe TD.. J Mech Behav Biomed Mater. 2015;55():87-103.

Integration of 3-D organoid bioprinting and microfluidic device technology for functional primary cell-based liver-on-a-chip operation [abstract]. Skardal A, Mead I, Devarasetty M, Kang H, Shupe T, Lee S, Jackson JD, Bishop CE, Yoo JJ, Soker S, Atala A.. Tissue Eng Part A. 2014;20(Suppl 1):S43.

Re-endothelialization of acellular liver scaffolds for whole organ engineering [abstract]. Ko I, Smith CJ, Li P, Peloso A, Dhal A, Clouse C, Zhao W, Shupe T, Atala A, Soker S, Yoo JJ.. Tissue Eng Part A. 2014;20(Suppl 1):S98.

Cell and organ bioengineering technology as applied to gastrointestinal diseases. Orlando G, Bendala JD, Shupe T, Bergman C, Bitar KN, Booth C, Carbone M, Koch KL, Lerut JP, Neuberger JM, Petersen B, Ricordi C, Atala A, Stratta RJ, Soker S.. Gut. 2013;62(5):774-786.

Immunogenicity of decellularized porcine liver for bioengineered hepatic tissue. Mirmalek-Sani SH, Sullivan DC, Zimmerman C, Shupe TD, Petersen BE.. Am J Pathol. 2013;183(2):558-565.

Characterization of a novel functional protein in the pancreatic islet: islet homeostasis protein regulation of glucagon synthesis in alpha cells. Oh S-H, Darwiche H, Cho J-H, Shupe T, Petersen BE.. Pancreas. 2012;41(1):22-30.

Growth factor retention on decellularized rat liver matrices derived from normal and regenerating liver [abstract]. Shupe T, Zimmerman C, Petersen B.. FASEB J. 2012;26(Meeting Abstracts Suppl):274.10.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Thomas D. Shupe, Ph.D.

Thomas D. Shupe, Ph.D.

Assistant Professor, Institute for Regenerative Medicine

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