Kaycee Michelle Sink, M.D., M.A.S.Wake Forest School of Medicine

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Kaycee Michelle Sink, M.D., M.A.S.

Acting Section Chief,
Medical Director,Kulynych Memory Assessment Clinic,
Associate Professor,

Clinical Interests

Polypharmacy, Geriatrics, Dementia, Behavioral Disturbances Associated with Cognitive Impairment

Contact Information

New Patient Appointments: 336-716-WAKE
Returning Patient Appointments: 336-713-8250
Department: 336-713-8570

Insurance Accepted »

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Education & Training

  • B.S., University of California-Davis, 1994
  • M.D., University of California-San Francisco, 1998
  • Master of Advanced Studies, University of California-San Francisco, 2005
  • Residency, Univ CA at San Francisco, 2001
  • Fellowship, University of California-San F, 2004

Board Certifications

  • American Board of Internal Medicine, Geriatric Medicine
  • American Board of Internal Medicine, Internal Medicine


  • Int Soc Adv Alzheimer's Res Tr
  • Am Geriatrics Society

NPI Number

  • 1285619247
Kaycee Michelle Sink, M.D., M.A.S.

Doctor Rating

No Rating Available
Why No Ratings?

Kaycee Michelle Sink, M.D., M.A.S.

Acting Section Chief, Gerontology and Geriatric Medicine
Medical Director,Kulynych Memory Assessment Clinic, Gerontology and Geriatric Medicine
Associate Professor, Gerontology and Geriatric Medicine

Research Interests

aging, alzheimer's disease, cardiac function, cognition/learning, sleep research

Contact Information

Academic: 336-713-8558 | Department: 336-713-8570

Media Medical Expert »

Recent Publications

Hughes TM, Sink KM. Hypertension and its role in cognitive function: current evidence and challenges for the future. Am J Hypertens. 2016;29(2):149-157.

Katula JA, Church T, Sink KM. Physical activity vs health education for cognition in sedentary older adults [reply to letter]. JAMA. 2016;315(4):415-416.

Gill TM, Pahor M, Guralnik JM, McDermott MM, King AC, Buford TW, Strotmeyer ES, Nelson ME, Sink KM, Demons JL, Kashaf SS, Walkup MP, Miller ME. Effect of structured physical activity on prevention of serious fall injuries in adults aged 70-89: randomized clinical trial (LIFE Study). BMJ. 2016;352():i245.

Williamson JD, Supiano MA, Applegate WB, Berlowitz DR, Campbell RC, Chertow GM, Fine LJ, Haley WE, Hawfield AT, Ix JH, Kitzman DW, Kostis JB, Krousel-Wood MA, Launer LJ, Oparil S, Rodriguez CJ, Roumie CL, Shorr RI, Sink KM, Wadley VG,. Intensive vs standard blood pressure control and cardiovascular disease outcomes in adults aged greater than or equal to 75 years: a randomized clinical trial. JAMA. 2016;315(24):2673-2682.

Sink KM, Divers J, Whitlow CT, Palmer ND, Smith SC, Xu J, Hugenschmidt CE, Wagner BC, Williamson JD, Bowden DW, Maldjian JA, Freedman BI. Cerebral structural changes in diabetic kidney disease: African American-Diabetes Heart Study MIND. Diabetes Care. 2015;38(2):206-212.

Kaup AR, Nettiksimmons J, Harris TB, Sink KM, Satterfield S, Metti AL, Ayonayon HN, Yaffe K. Cognitive resilience to apolipoprotein E epsilon4: contributing factors in black and white older adults. JAMA Neurol. 2015;72(3):340-348.

Hugenschmidt CE, Sink KM. No pain, functional gain: the importance of pain management in older adults with cognitive impairment. Pain. 2015;156(8):1377-1378.

Williams JA, Sink KM, Tooze JA, Atkinson HH, Cauley JA, Yaffe K, Tylavsky FA, Rubin SM, Simonsick EM, Kritchevsky SB, Houston DK. Low 25-hydroxyvitamin D concentrations predict incident depression in well-functioning older adults: the Health, Aging, and Body Composition Study. J Gerontol A Biol Sci Med Sci. 2015;70(6):757-763.

Applegate WB, Sink KM, Williamson JD. Managing high blood pressure in older persons with decline in function [editorial]. Am J Kidney Dis. 2015;66(5):745-747.

Whitlow CT, Sink KM, Divers J, Smith SC, Xu J, Palmer ND, Hugenschmidt CE, Williamson JD, Bowden DW, Freedman BI, Maldjian JA. Effects of type 2 diabetes on brain structure and cognitive function: African American-Diabetes Heart Study MIND. AJNR Am J Neuroradiol. 2015;36(9):1648-1653.

Espeland MA, Newman AB, Sink K, Gill TM, King AC, Miller ME, Guralnik J, Katula J, Church T, Manini T, Reid KF, McDermott MM. Associations between ankle-brachial index and cognitive function: results from the Lifestyle Interventions and Independence for Elders Trial. J Am Med Dir Assoc. 2015;16(8):682-689.

Still CH, Craven TE, Freedman BI, Van Buren PN, Sink KM, Killeen AA, Bates JT, Bee A, Contreras G, Oparil S, Pedley CM [sic] [Pedley CF], Wall BM, White S, Woods DM, Rodriguez CJ, Wright JT Jr. Baseline characteristics of African Americans in the Systolic Blood Pressure Intervention Trial. J Am Soc Hypertens. 2015;9(9):670-679.

Vaughan L, Hogan PE, Rapp SR, Dugan E, Marottoli RA, Snively BM, Shumaker SA, Sink KM. Driving with mild cognitive impairment or dementia: cognitive test performance and proxy report of daily life function in older women. J Am Geriatr Soc. 2015;63(9):1774-1782.

Gifford A, Lawrence J, Case D, Rapp S, Baker L, Craft S, Groteluschen DL, Klepin H, Lesser G, Naughton MJ, Sachs B, Samuel TA, Sink K, Williamson, J, Shaw EG. Mild cognitive impairment (MCI) in chemotherapy-treated breast cancer survivors [abstract]. J Clin Oncol. 2015;33(15 Suppl):9560.

Sink KM, Espeland MA, Castro CM, Church T, Cohen R, Dodson JA, Guralnik J, Hendrie HC, Jennings J, Katula J, Lopez OL, McDermott MM, Pahor M, Reid KF, Rushing J, Verghese J, Rapp S, Williamson JD. Effect of a 24-month physical activity intervention vs health education on cognitive outcomes in sedentary older adults: the LIFE randomized trial. JAMA. 2015;314(8):781-790.

Freedman BI, Divers J, Whitlow CT, Bowden DW, Palmer ND, Smith SC, Xu J, Register TC, Carr JJ, Wagner BC, Williamson JD, Sink KM, Maldjian JA. Subclinical atherosclerosis is inversely associated with gray matter volume in African Americans with type 2 diabetes. Diabetes Care. 2015;38(11):2158-2165.

Wright JT Jr, Williamson JD, Whelton PK, Snyder JK, Sink KM, Rocco MV, Reboussin DM, Rahman M, Oparil S, Lewis CE, Kimmel PL, Johnson KC, Goff DC Jr, Fine LJ, Cutler JA, Cushman WC, Cheung AK, Ambrosius WT. A randomized trial of intensive versus standard blood-pressure control. N Engl J Med. 2015;373(22):2103-2116.

Sink KM, Craft S, Smith SC, Maldjian JA, Bowden DW, Xu J, Freedman BI, Divers J. Montreal cognitive assessment and modified mini mental state examination in African Americans. J Aging Res. 2015;2015():872018.

Klepin HD, Geiger AM, Bandos H, Costantino JP, Rapp SR, Sink KM, Lawrence JA, Atkinson HH, Espeland MA. Cognitive factors associated with adherence to oral antiestrogen therapy: results from the cognition in the study of tamoxifen and raloxifene (Co-STAR) study. Cancer Prev Res (Phila Pa). 2014;7(1):161-168.

Wilson VK, Houston DK, Kilpatrick L, Lovato J, Yaffe K, Cauley JA, Harris TB, Simonsick EM, Ayonayon HN, Kritchevsky SB, Sink KM. Relationship between 25-hydroxyvitamin d and cognitive function in older adults: the health, aging and body composition study. J Am Geriatr Soc. 2014;62(4):636-641.

Hall D, Wilkerson J, Lovato J, Sink K, Chamberlain D, Alli R, Clarke P, Rogers S, Villalba J, Williams J, Shaw EG. Variables associated with high caregiver stress in patients with mild cognitive impairment or Alzheimer's disease: implications for providers in a co-located memory assessment clinic. J Ment Health Couns. 2014;36(2):145-159.

Sink KM, Chelune G, Coker L, Gaussoin S, Lerner A, Nichols L, Pajewski NM, Rapp S, Wadley V, Williamson J. The Montreal Cognitive Assessment (MoCA) in 8,724 SPRINT participants [abstract]. J Am Geriatr Soc. 2014;62(Suppl 1):S9-S10.

Ambrosius WT, Sink KM, Foy CG, Berlowitz DR, Cheung AK, Cushman WC, Fine LJ, Goff DC Jr, Johnson KC, Killeen AA, Lewis CE, Oparil S, Reboussin DM, Rocco MV, Williamson JD, Wright JT Jr, Whelton PK. The design and rationale of a multicenter clinical trial comparing two strategies for control of systolic blood pressure: the Systolic Blood Pressure Intervention Trial (SPRINT). Clin Trials. 2014;11(5):532-546.

Pahor M, Guralnik JM, Ambrosius WT, Blair S, Bonds DE, Church TS, Espeland MA, Fielding RA, Gill TM, Groessl EJ, King AC, Kritchevsky SB, Manini TM, McDermott MM, Miller ME, Newman AB, Rejeski WJ, Sink KM, Williamson JD. Effect of structured physical activity on prevention of major mobility disability in older adults: the LIFE study randomized clinical trial. JAMA. 2014;311(23):2387-2396.

Demons JL, Chenna S, Callahan KE, Davis BR, Kearsley L, Sink KM, Watkins FS, Williamson JD, Atkinson HH. Utilizing a Meals on Wheels program to teach falls risk assessment to medical students. Gerontol Geriatr Educ. 2014;35(4):409-420.

Sink KM, Espeland MA, Rushing J, Castro CM, Church TS, Cohen R, Gill TM, Henkin L, Jennings JM, Kerwin DR, Manini TM, Myers V, Pahor M, Reid KF, Woolard N, Rapp SR, Williamson JD. The LIFE Cognition Study: design and baseline characteristics. Clin Interv Aging. 2014;9():1425-1436.

Palmer ND, Sink KM, Smith SC, Xu J, Bowden DW, Hugenschmidt CE, Whitlow CT, Williamson JD, Maldjian JA, Divers J, Freedman BI. Kidney disease and cognitive function: African American-Diabetes Heart Study MIND. Am J Nephrol. 2014;40(3):200-207.

Al Hazzouri AZ, Newman AB, Simonsick E, Sink KM, Sutton Tyrrell K, Watson N, Satterfield S, Harris T, Yaffe K. Pulse wave velocity and cognitive decline in elders: the Health, Aging, and Body Composition study. Stroke. 2013;44(2):388-393.

Spencer SK, Smart J, Stephenson D, Bain M, Sink KM. Palliative Care Readiness: a caregiver survey of patients with mild cognitive impairment or dementia [abstract]. J Am Geriatr Soc. 2013;61(Suppl 1):S88-S89.

Wilson V, Espeland M, Rapp S, Oles K, Gass M, Thomas A, Sherwin B, Sink K. Prevalence of anticholinergic drug use and impact on cognition in older women: results from the Women's Health Initiative Memory Study (WHIMS) [abstract]. J Am Geriatr Soc. 2013;61(Suppl 1):S14.

Yasar S, Xia J, Yao W, Furberg CD, Xue QL, Mercado CI, Fitzpatrick AL, Fried LP, Kawas CH, Sink KM, Williamson JD, DeKosky ST, Carlson MC. Antihypertensive drugs decrease risk of Alzheimer disease: Ginkgo Evaluation of Memory Study. Neurology. 2013;81(10):896-903.

Divers J, Hugenschmidt C, Sink KM, Williamson JD, Ge Y, Smith SC, Bowden DW, Whitlow CT, Lyders E, Maldjian JA, Freedman BI. Cerebral white matter hyperintensity in African Americans and European Americans with type 2 diabetes. J Stroke Cerebrovasc Dis. 2013;22(7):e46-52.

Atkinson HH, Lambros A, Davis BR, Lawlor JS, Lovato J, Sink KM, Demons JL, Lyles MF, Watkins FS, Callahan KE, Williamson JD. Teaching medical student geriatrics competencies in 1 week: an efficient model to teach and document selected competencies using clinical and community resources. J Am Geriatr Soc. 2013;61(7):1182-1187.

Hall D, Wilkerson J, Lovato J, Sink K, Chamberlain D, Clarke P, Villalba J, Alli R, Williams J, Rogers S, Shaw E. Mental health symptoms in people with cognitive impairment and memory loss and their caregivers: initial finding and implications for counselors and geriatricians [abstract]. Alzheimers Dement. 2013;9(4 Suppl):P485-P486.

Sink K, Lovato J, Chamberlain D, Alli R, Clarke P, Hall D, Villalba J, Shaw E. High neuroticism in caregivers is associated with greater burden independent of degree of cognitive impairment or neuropsychiatric symptoms [abstract]. Alzheimers Dement. 2013;9(4 Suppl):P493.

Sink K, Chmelo E, Nicklas B, Katula J, Cofman C, Williamson J, Baker L. Pilot trial of buddy-assisted exercise in people with mild cognitive impairment [abstract]. Alzheimers Dement. 2013;9(4 Suppl):P494.

Alli R, Hall D, Clarke P, Hugenschmidt C, Rogers S, Sink K, Villalba J, Williams J, Wilson V, Shaw E. An interdisciplinary counseling center for individuals, couples and families afftected by MCI and dementia [abstract]. Alzheimers Dement. 2013;9(4 Suppl):P646.

Shaw E, Hall D, Lovato J, Alli R, Clarke P, Villalba J, Sink K. Caregiver Burden Scale item analysis: implications for mental health counseling approaches [abstract]. Alzheimers Dement. 2013;9(4 Suppl):P646.

Neth B, Colmer HG IV, Hugenschmidt C, Fitzsimmons S, Shaw E, Alli R, Sun D, Henningsen D, Mugweru J, Sink K. A brain fitness program for people with dementia concurrent with a support group for their caregivers is feasible [abstract]. Alzheimers Dement. 2013;9(4 Suppl):P647-P648.

Baker L, Craft S, Cholerton B, Wilkinson C, Foster-Schubert K, McTiernan A, Williamson J, Sink K, Duncan G. Aerobic exercise effects on cognition in at-risk adults: role of insulin sensitivity and APOE-epsilon 4 [abstract]. Alzheimers Dement. 2013;9(4 Suppl):P690.

Clarke PB, Shaw EG, Villalba JA, Alli R, Sink KM. Therapeutic interactions to enhance the mental health and wellness of dementia caregivers and patients. J Gerontol Nurs. 2013;39(11):7-10.

Espeland MA, Katula JA, Rushing J, Kramer AF, Jennings JM, Sink KM, Nadkarni NK, Reid KF, Castro CM, Church T, Kerwin DR, Williamson JD, Marottoli RA, Rushing S, Marsiske M, Rapp SR. Performance of a computer-based assessment of cognitive function measures in two cohorts of seniors. Int J Geriatr Psychiatry. 2013;28(12):1239-1250.

Casanova R, Hsu FC, Sink KM, Rapp SR, Williamson JD, Resnick SM, Espeland MA. Alzheimer's disease risk assessment using large-scale machine learning methods. PLoS One. 2013;8(11):e77949.

Vaughan L, Leng I, Dagenbach D, Resnick SM, Rapp SR, Jennings JM, Brunner RL, Simpson SL, Beavers DP, Coker LH, Gaussoin SA, Sink KM, Espeland MA. Intraindividual variability in domain-specific cognition and risk of mild cognitive impairment and dementia. Curr Gerontol Geriatr Res. 2013;():495793.

Attia M, Sink KM, Higgins A, Yacoub G, Case D, Klepin H, Lawrence JA. CNS tools and oncology: feasibility of cognition assessment prior to initial chemotherapy in an oncology clinic [abstract]. Gerontologist. 2013;53(Suppl 1):321-322.

Sink KM, Corbett M, Dugan E, Espeland MA, Hogan P, Rapp S, Vaughan L, Shumaker SA. (CNS) prevalence and predictors of driving among cognitively impaired older adults: the Women's Health Initiative Memory Study-epidemiology of cognitive health outcomes (WHIMS-ECHO) [abstract]. Gerontologist. 2013;53(Suppl 1):7.

Sink KM, Castro CM, Church T, Gill TM, Henkin L, Kerwin DR, Manini T, Myers VH. Life-cognition: design and baseline data [abstract]. Gerontologist. 2013;53(Suppl 1):548.

Chenna S, Sink KM, Callahan K, Demons J, Atkinson H. Teaching fall risk assessment to medical students using Meals on Wheels [abstract]. J Am Geriatr Soc. 2012;60(Suppl 4):S40-S41.

Wilson V, Neiberg R, Tooze JA, Sink KM, Shea K, Williamson J, Kitzman DW, Hausman DB, Cauley J, Bauer D, Harris T, Kritchevsky SB, Houston DK. 25-hydroxyvitamin D and cardiovascular disease in the Health ABC Study [abstract]. J Am Geriatr Soc. 2012;60(Suppl 4):S89.

Yasar S, Lin F-M, Fried LP, Kawas CH, Sink KM, DeKosky ST, Carlson MC. Diuretic use is associated with better learning and memory in older adults in the Ginkgo Evaluation of Memory Study. Alzheimers Dement. 2012;8(3):188-195.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Associate Professor, Gerontology and Geriatric Medicine

Clinical Interests

Polypharmacy, Geriatrics, Dementia, Behavioral Disturbances Associated with Cognitive Impairment
Kaycee Michelle Sink, M.D., M.A.S.

Kaycee Michelle Sink, M.D., M.A.S.

Acting Section Chief, Gerontology and Geriatric Medicine
Medical Director,Kulynych Memory Assessment Clinic, Gerontology and Geriatric Medicine
Associate Professor, Gerontology and Geriatric Medicine

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