Profile

Aleksander Skardal, Ph.D.Wake Forest School of Medicine

Aleksander Skardal, Ph.D.

Assistant Professor,

Contact Information

Academic: 425-301-3122 | Department: 336-716-2011

Email: askardal@wakehealth.edu

Education & Training

  • B.Sc., Johns Hopkins University, 2005
  • Fellowship, WFU School of Medicine, 2014
Aleksander Skardal, Ph.D.

Aleksander Skardal, Ph.D.

Assistant Professor, Institute for Regenerative Medicine
Cancer Biology

Research Interests

biotechnology, cancer/oncogenesis

Contact Information

Academic: 425-301-3122 | Department: 336-716-2011

Email: askardal@wakehealth.edu

Recent Publications

Skardal A, Devarasetty M, Forsythe S, Atala A, Soker S. A reductionist metastasis-on-a-chip platform for in vitro tumor progression modeling and drug screening. Biotechnol Bioeng. 2016;():.

Skardal A, Devarasetty M, Kang HW, Seol YJ, Forsythe SD, Bishop C, Shupe T, Soker S, Atala A. Bioprinting cellularized constructs using a tissue-specific hydrogel bioink [video article]. J Vis Exp. 2016;(110):.

Skardal A, Atala A. Biomaterials for integration with 3-D bioprinting. Ann Biomed Eng. 2015;43(3):730-746.

Skardal A, Devarasetty M, Rodman C, Atala A, Soker S. Liver-tumor hybrid organoids for modeling tumor growth and drug response in vitro. Ann Biomed Eng. 2015;43(10):2361-2373.

Skardal A, Devarasetty M, Kang HW, Mead I, Bishop C, Shupe T, Lee SJ, Jackson J, Yoo J, Soker S, Atala A. A hydrogel bioink toolkit for mimicking native tissue biochemical and mechanical properties in bioprinted tissue constructs. Acta Biomater. 2015;25():24-34.

Skardal A. Bioprinting essentials of cell and protein viability In: Atala A, Yoo JJ, eds. Essentials of 3D biofabrication and translation. London (UK): Elsevier/Academic Press;2015: 1-17.

Devarasetty M, Forsythe S, Soker S, Hall A, Skardal A. Ultra-thin tissue-tumor organoid microfluidic platforms for in vitro diagnostics [abstract]. Tissue Eng Part A. 2015;21(Suppl 1):S262-S263.

Devarasetty M, Skardal A, Soker S. A 3D stratified colon model for colorectal cancer progression [abstract]. Tissue Eng Part A. 2015;21(Suppl 1):S196.

Murphy S, Skardal A, Sutton K, Reid T, Song L, Jackson J, Atala A. Amnion membrane hydrogel accelerates skin wound healing [abstract]. Tissue Eng Part A. 2015;21(Suppl 1):S155.

Skardal A, Devarasetty M, Soker S, Hall AR. In situ patterned micro 3D liver constructs for parallel toxicology testing in a fluidic device. Biofabrication. 2015;7(3):031001.

Seol Y, Kang H, Lee S, Jackson JD, Skardal A, Shupe T, Soker S, Bishop C, Yoo JJ, Atala A. 3-D bioprinting of tissue organoids for body-on-a-chip drug screening platform [abstract]. Tissue Eng Part A. 2015;21(Suppl 1):S369.

Skardal A, Devarasetty M, Kang H, Mead I, Bishop C, Shupe T, Lee S, Jackson J, Yoo J, Soker S, Atala A. A hydrogel bioink toolkit for bioprinting tissue constructs while mimicking native tissue biochemical and mechanical properties [abstract]. Tissue Eng Part A. 2015;21(Suppl 1):S212.

Skardal A, Kleensang A, Devarasetty M, Kang H, Mead I, Bishop C, Shupe T, Lee S, Jackson J, Yoo J, Hartung T, Soker S, Atala A. Physiologically relevant drug testing in vitro - an integrated multiple organoid-on-a-chip approach [abstract]. Tissue Eng Part A. 2015;21(Suppl 1):S362.

Yi H, Forsythe S, Zhang Y, Skardal A. Bio-functionalized alginate hydrogels for improved cell-matrix interactions and growth factor sequestration kinetics [abstract]. Tissue Eng Part A. 2015;21(Suppl 1):S187.

Deegan DB, Zimmerman C, Skardal A, Atala A, Shupe TD. Stiffness of hyaluronic acid gels containing liver extracellular matrix supports human hepatocyte function and alters cell morphology. J Mech Behav Biomed Mater. 2015;55():87-103.

Niu G, Choi JS, Wang Z, Skardal A, Giegengack M, Soker S. Heparin-modified gelatin scaffolds for human corneal endothelial cell transplantation. Biomaterials. 2014;35(13):4005-4014.

Devarasetty M, Atala A, Soker S, Skardal A. A metastasis-on-a-chip system for modeling colon carcinoma migration and invasion in vitro [abstract]. Tissue Eng Part A. 2014;20(Suppl 1):S15.

Devarasetty M, Skardal A, Soker S. Modeling the colon-tumor microenvironment using multicellular hydrogel strata [abstract]. Tissue Eng Part A. 2014;20(Suppl 1):S77.

Murphy SV, Skardal A, Sutton K, Reid T, Rebecca H, Song L, Jackson J, Atala A. Amnion hydrogel accelerates skin wound healing [abstract]. Tissue Eng Part A. 2014;20(Suppl 1):S85.

Skardal A, Devarasetty M, Atala A, Soker S, Hall A. A microfluidic platform for parallel analysis of in situ patterned 3-D liver organoids [abstract]. Tissue Eng Part A. 2014;20(Suppl 1):S68-S69.

Skardal A, Devarasetty M, Rodman C, Atala A, Soker S. An in vitro 3-D liver-tumor hybrid organoid system for modeling metastasis and drug resistance [abstract]. Tissue Eng Part A. 2014;20(Suppl 1):S15.

Skardal A, Mead I, Devarasetty M, Kang H, Shupe T, Lee S, Jackson JD, Bishop CE, Yoo JJ, Soker S, Atala A. Integration of 3-D organoid bioprinting and microfluidic device technology for functional primary cell-based liver-on-a-chip operation [abstract]. Tissue Eng Part A. 2014;20(Suppl 1):S43.

Skardal A, Mack D, Atala A, Soker S. Substrate elasticity controls cell proliferation, surface marker expression and motile phenotype in amniotic fluid-derived stem cells. J Mech Behav Biomed Mater. 2013;17():307-316.

Murphy SV, Skardal A, Atala A. Evaluation of hydrogels for bio-printing applications. J Biomed Mater Res A. 2013;101(1):272-284.

Markert CD, Guo X, Skardal A, Bharadwaj S, Zhang Y, Bonin K, Guthold M. How stiff is it? Characterizing the micro-scale elastic modulus of hydrogels for use in regenerative medicine [abstract]. FASEB J. 2013;27():1217.21.

Markert CD, Guo X, Skardal A, Wang Z, Bharadwaj S, Zhang Y, Bonin K, Guthold M. Characterizing the micro-scale elastic modulus of hydrogels for use in regenerative medicine. J Mech Behav Biomed Mater. 2013;27():115-127.

Skardal A, Smith L, Bharadwaj S, Atala A, Soker S, Zhang Y. Tissue specific synthetic ECM hydrogels for 3-D in vitro maintenance of hepatocyte function. Biomaterials. 2012;33(18):4565-4575.

Mack DL, Skardal A, Yoo J, Soker S. Bioprinted amniotic fluid-derived stem cells accelerate wound healing in skin [abstract]. Mol Ther. 2012;20(Suppl 1):S285.

Skardal A, Mack D, Kapetanovic E, Atala A, Jackson JD, Yoo J, Soker S. Bioprinted amniotic fluid-derived stem cells accelerate healing of large skin wounds. Stem Cells Transl Med. 2012;1(11):792-802.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Aleksander Skardal, Ph.D.

Aleksander Skardal, Ph.D.

Assistant Professor, Institute for Regenerative Medicine
Cancer Biology

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