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William E. Swords, Ph.D.

William E. Swords, Ph.D.

Associate Professor, Microbiology & Immunology
WFU Primate Center
Molecular Medicine
Contact Information
Office:
336-716-2011
Email: wswords@wakehealth.edu
Education & Training
  BS Auburn University-Auburn 1988
  MS Mississippi State University 1990
  PhD University of Alabama-Birmingham 1996
Fellowship Bacteriology University of Iowa 2001
Memberships
American Society of Microbiology
William E. Swords, Ph.D.

William E. Swords, Ph.D.

Associate Professor, Microbiology & Immunology
WFU Primate Center
Molecular Medicine
Contact Information
Office:
336-716-2011
Email: wswords@wakehealth.edu
Research Interests
congenital defects , immunology/allergy/inflammatio , infectious diseases
Recent Publications
Juneau RA, Pang B, Weimer KED, Armbruster CE, Swords WE. Nontypeable Haemophilus influenzae initiates formation of neutrophil extracellular traps. Infect Immun. 2011; 79(1):431-438.

Weimer KED, Juneau RA, Murrah KA, Pang B, Armbruster CE, Richardson SH, Swords WE. Divergent mechanisms for passive pneumococcal resistance to beta-lactam antibiotics in the presence of Haemophilus influenzae. J Infect Dis. 2011; 203(4):549-555.

Byrd MS, Pang B, Hong W, Waligora EA, Juneau RA, Armbruster CE, Weimer KED, Murrah K, Lu H, Sprinkle A, Kock ND, Swords WE, et al. Direct evaluation of Pseudomonas aeruginosa biofilm mediators in a chronic infection model. Infect Immun. 2011; 79(8):3087-3095.

Armbruster CE, Pang B, Murrah K, Juneau RA, Perez AC, Weimer KED, Swords WE. RbsB (NTHI_0632) mediates quorum signal uptake in nontypeable Haemophilus influenzae strain 86-028NP. Mol Microbiol. 2011; 82(4):836-850.

Byrd MS, Pang B, Mishra M, Swords WE, Wozniak DJ. The Pseudomonas aeruginosa exopolysaccharide Psl facilitates surface adherence and NF-kappaB activation in A549 cells. mBio. 2010; 1(3):e00140-10.

Armbruster CE, Hong W, Pang B, Weimer KED, Juneau RA, Turner J, Swords WE. Indirect pathogenicity of Haemophilus influenzae and Moraxella catarrhalis in polymicrobial otitis media occurs via interspecies quorum signaling. mBio. 2010; 1(3):e00102-10.

Weimer KED, Armbruster CE, Juneau RA, Hong W, Pang B, Swords WE. Coinfection with Haemophilus influenzae promotes pneumococcal biofilm formation during experimental otitis media and impedes the progression of pneumococcal disease. J Infect Dis. 2010; 202(7):1068-1075.

Armbruster CE, Swords WE. Interspecies bacterial communication as a target for therapy in otitis media [editorial]. Expert Rev Anti Infect Ther. 2010; 8(10):1067-1070.

Doern CD, Roberts AL, Hong W, Nelson J, Lukomski S, Swords WE, Reid SD. Biofilm formation by group A Streptococcus: a role for the streptococcal regulator of virulence (Srv) and streptococcal cysteine protease (SpeB). Microbiology. 2009; 155(Pt 1):46-52.

Reid SD, Hong W, Dew KE, Winn DR, Pang B, Watt J, Glover DT, Hollingshead SK, Swords WE. Streptococcus pneumoniae forms surface-attached communities in the middle ear of experimentally infected chinchillas. J Infect Dis. 2009; 199(6):786-794.

Hong W, Juneau RA, Pang B, Swords WE. Survival of bacterial biofilms within neutrophil extracellular traps promotes nontypeable Haemophilus influenzae persistence in the chinchilla model for otitis media. J Innate Immun. 2009; 1(3):215-224.

Armbruster CE, Hong W, Pang B, Dew KE, Juneau RA, Byrd MS, Love CF, Kock ND, Swords WE. LuxS promotes biofilm maturation and persistence of nontypeable haemophilus influenzae in vivo via modulation of lipooligosaccharides on the bacterial surface. Infect Immun. 2009; 77(9):4081-4091.

Pang B, Winn D, Johnson R, Hong W, West-Barnette S, Kock N, Swords WE. Lipooligosaccharides containing phosphorylcholine delay pulmonary clearance of nontypeable Haemophilus influenzae. Infect Immun. 2008; 76(5):2037-2043.

Pang B, Hong W, West-Barnette SL, Kock ND, Swords WE. Diminished ICAM-1 expression and impaired pulmonary clearance of nontypeable Haemophilus influenzae in a mouse model of chronic obstructive pulmonary disease/emphysema. Infect Immun. 2008; 76(11):4959-4967.

Hong W, Mason K, Jurcisek J, Novotny L, Bakaletz LO, Swords WE. Phosphorylcholine decreases early inflammation and promotes the establishment of stable biofilm communities of nontypeable Haemophilus influenzae strain 86-028NP in a chinchilla model of otitis media. Infect Immun. 2007; 75(2):958-965.

Hong W, Pang B, West-Barnette S, Swords WE. Phosphorylcholine expression by nontypeable Haemophilus influenzae correlates with maturation of biofilm communities in vitro and in vivo. J Bacteriol. 2007; 189(22):8300-8307.

Sandal I, Hong W, Swords WE, Inzana TJ. Characterization and comparison of biofilm development by pathogenic and commensal isolates of Histophilus somni. J Bacteriol. 2007; 189(22):8179-8185.
All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

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Last Updated 3/13/2012
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