Profile

Elisabeth A. Tallant, Ph.D.Wake Forest School of Medicine

Elisabeth A. Tallant, Ph.D.

Assistant Director,
Professor,
Redox Biology & Medicine Ctr

Contact Information

Academic: 336-716-2108 | Department: 336-716-2108

Email: atallant@wakehealth.edu

Education & Training

  • B.S., University of Memphis, 1974
  • Ph.D., University of Tennessee-Memphis, 1983
  • Fellowship, University of Alabama-Birmingh, 1986

Memberships

  • Am Assn Of Advancement Of Scie
  • Am Assn for Cancer Research
  • Am Soc Biochem Molecular Bio
  • Am Heart Association
  • Am Physiological Society
  • Cons for SE Hypertension Contr
  • Council For High Blood Pressur
Elisabeth A. Tallant, Ph.D.

Elisabeth A. Tallant, Ph.D.

Assistant Director, Hypertension and Vascular Research Center
Professor, Hypertension
Redox Biology & Medicine Ctr

Contact Information

Academic: 336-716-2108 | Department: 336-716-2108

Email: atallant@wakehealth.edu

Recent Publications

Angiotensin-(1-7) attenuates skeletal muscle fibrosis and stiffening in a mouse model of extremity sarcoma radiation therapy. Willey JS, Bracey DN, Gallagher PE, Tallant EA, Wiggins WF, Callahan MF, Smith TL, Emory CL.. J Bone Joint Surg Am. 2016;98(1):48-55.

Beneficial cardiovascular effects of muscadine grape extract in normotensive female rats [abstract]. Duncan AV, Shaltout HA, Tommasi EN, Gallagher PE, Tallant EA, Diz DI.. FASEB J. 2016;30(1 Suppl):1175.7.

Angiotensin-(1-7) prevents angiotensin II-induced fibrosis in cremaster microvessels. Carver KA, Smith TL, Gallagher PE, Tallant EA.. Microcirculation. 2015;22(1):19-27.

Angiotensin-(1-7) targets c-Met signaling by up-regulating the phosphatase PTP1b to reduce triple negative breast cancer [abstract]. Deng G, Metheny-Barlow L, Gallagher PE, Tallant EA.. Cancer Res. 2015;75(15 Suppl):4981.

Prevention of breast tumor growth by an extract from the muscadine grape [abstract]. Gallagher PE, Tallant EA.. Cancer Res. 2015;75(15 Suppl):2825.

Muscadine grape extract reduces lung carcinogenesis in female mice exposed to 3-methylcholanthrene in utero [abstract]. Porter BE, Moore JE, Miller MS, Tallant EA, Gallagher PE.. Cancer Res. 2015;75(15 Suppl):4563.

Angiotensin-(1-7) prevents fibrosis in doxorubicin-treated rats [abstract]. Rahimi OA, Castellino SM, Cammock CE, Tallant EA, Gallagher PE.. Cancer Res. 2015;75(15 Suppl):4489.

Angiotensin-(1-7): a peptide hormone with anti-cancer activity. Gallagher PE, Arter AL, Deng G, Tallant AE.. Curr Med Chem. 2014;21(21):2417-2423.

The endogenous peptide angiotensin-(1-7) prevents radiation-induced muscle fibrosis: an in vivo murine model [abstract]. Bracey DN, Willey JS, Tallant EA, Gallagher PE, Wiggins WF, Callahan MF, Smith TL, Emory CL.. In: Proceedings of the 2014 Annual Meeting of the American Academy of Orthopaedic Surgeons; 2014 March 15-18; New Orleans (LA). 2014;():.

Blockade of angiotensin-(1-7)-mediated vascular remodeling by a CB2 cannabinoid receptor antagonist [abstract]. Tallant EA, Howlett AC, Gallagher PE.. Hypertension. 2014;64(Suppl 1):A542.

Angiotensin-(1-7) attenuates triple negative breast cancer progression bytargeting C-Met and downstream ERK1/2 signaling [abstract]. Deng G, Tallant EA, Gallagher P.. Mol Cancer Res. 2014;12(Suppl 12):A30.

Angiotensin-(1-7) attenuates metastatic prostate cancer and reduces osteoclastogenesis. Krishnan B, Smith TL, Dubey P, Zapadka ME, Torti FM, Willingham MC, Tallant EA, Gallagher PE.. Prostate. 2013;73(1):71-82.

Angiotensin-(1-7) reduces proliferation and angiogenesis of human prostate cancer xenografts with a decrease in angiogenic factors and an increase in sFlt-1. Krishnan B, Torti FM, Gallagher PE, Tallant EA.. Prostate. 2013;73(1):60-70.

Angiotensin II/angiotensin-(1-7). Gallagher PE, Arter AL, Krishnan B, Garcia-Espinosa MA, Tallant EA. In: Kastin AJ, ed. Handbook of biologically acive peptides. 2nd ed. Oxford: Academic Press;2013: 494-501.

The endogenous peptide angiotensin-(1-7) prevents radiation-induced muscle fibrosis: an in vivo murine model [abstract]. Bracey D, Willey JS, Tallant EA, Gallagher PD [sic] [Gallagher PE], Smith TL, Callahan MF, Emory CL.. Int J Radiat Oncol Biol Phys. 2013;87(2 Suppl):S167.

The CB2 cannabinoid receptor mediates the anti-proliferative actions of angiotensin-(1-7) in vascular smooth muscle cells [abstract]. Tallant EA, Howlett A, Grabenauer M, Thomas BF, Gallagher PE.. Hypertension. 2013;62(3 Suppl):465.

Angiotensin-(1-7) prevents radiation-induced muscle fibosis: an in vivo murine model [abstract]. Bracey DN, Willey JS, Tallant EA, Gallagher PE, Smith TL, Callahan MF, Emory CL.. In: Proceedings of the 2013 Annual Meeting of the Southern Orthopedic Association; 2013 July 30-August 2; Palm Beach (FL). 2013;():.

The CB2cannabinoid receptor mediates the anti-proliferative actions of angiotensin-(1-7) in vascular smooth muscle cells [abstract]. Tallant EA, Howlett A, Grabenauer M, Thomas BF, Gallagher PE.. In: Conference Program of the 2013 Carolina Cannabinoid Collaborative Conference; 2013 Oct 25-27; Richmond (VA). 2013;():.

Angiotensin-(1-7) attenuates the proliferation of cancer-associated fibroblasts in triple negative breast cancer [abstract]. Arter AL, Gallagher PE, Tallant EA.. Cancer Res. 2013;73(3 Suppl):B34.

Angiotensin-(1-7) suppresses lung metastasis in the 4T1 orthotopic mammary carcinoma model [abstract]. Arter A, Gallagher PE, Tallant AE [sic] [Tallant EA].. In: Proceedings of the 2013 International Conference on Tumor Microenvironment and Cellular Stress; 2013 Sept 27-Oct 2; Corfu (Greece). 2013;():.

Angiotensin-(1-7) attenuates angiotensin II-induced cardiac remodeling associated with upregulation of dual-specificity phosphatase 1. McCollum LT, Gallagher PE, Tallant EA.. Am J Physiol Heart Circ Physiol. 2012;302(3):H801-H810.

Angiotensin-(1-7) abrogates mitogen-stimulated proliferation of cardiac fibroblasts. McCollum LT, Gallagher PE, Tallant EA.. Peptides. 2012;34(2):380-388.

Angiotensin-(1-7), a peptide hormone with therapeutic potential for the treatment of glioblastomas [abstract]. Garcia-Espinosa MA, Lesser GJ, Debinski W, Tallant EA, Gallagher PE.. In: Proceedings of the 103rd Annual Meeting of the Amerian Association for Cancer Research; 2012 Mar 31-Apr 4; Chicago, Illinois. Philadelphia (PA): AACR. 2012;():Abstr 1938.

Angiotensin-(1-7) inhibits proliferative and fibrotic signaling mechanisms in triple negative breast cancer [abstract]. Arter AA, Metheny-Barlow L, Gallagher PE, Tallant EA.. In: Proceedings of the 103rd Annual Meeting of the Amerian Association for Cancer Research; 2012 Mar 31-Apr 4; Chicago, Illinois. Philadelphia (PA): AACR. 2012;():Abstr 5224.

Differences in oxidative stress status and expression of MKP-1 in dorsal medulla of transgenic rats with altered brain renin-angiotensin system. Nautiyal M, Katakam PV, Busija DW, Gallagher PE, Tallant EA, Chappell MC, Diz DI.. Am J Physiol Regul Integr Comp Physiol. 2012;303(8):R799-806.

Vascular remodeling by angiotensin peptide hormones alters reactivity of the microcirculation [abstract]. Carver KA, Smith TL, Gallagher PE, Tallant EA.. Hypertension. 2012;60(3 Suppl):530.

Angiotensin-(1-7) attenuates PDGF-dependent migration of vascular smooth muscle cells [abstract]. Tallant EA, Carver KA, Gallagher PE.. Hypertension. 2012;60(3 Suppl):512.

Angiotensin-(1-7) inhibits the growth of human pediatric rhabdomyosarcoma in a mouse xenograft model [abstract]. Gallagher PE, Maglic D, Krishnan B, Castellino SM, Tallant EA.. In: Proceedings of the 102nd Annual Meeting of the American Association for Cancer Research; 2011 Apr 2-6; Orlando (FL). Philadelphia (PA): AACR. 2011;():Abstr 5349.

Angiotensin peptides and lung cancer. Gallagher PE, Cook K, Soto-Pantoja D, Menon J, Tallant EA.. Curr Cancer Drug Targets. 2011;11(4):394-404.

Angiotensin peptides and central autonomic regulation. Diz DI, Arnold AC, Nautiyal M, Isa K, Shaltout HA, Tallant EA.. Curr Opin Pharmacol. 2011;11(2):131-137.

Angiotensin-(1-7) attenuates angiotensin II-induced fibrosis through a reduction in connective tissue growth factor [abstract]. Carver KA, Smith TL, Gallagher PE, Tallant EA.. Hypertension. 2011;58(5):e178.

Angiotensin-(1-7) reduces cardiac hypertrophy and fibrosis in mRen2.Lewis congenic rats [abstract]. Tallant EA, Carver KA, Gallagher PE.. Hypertension. 2011;58(5):e110.

Inhibition of cancer cell growth by muscadine grape seed and grape skin extracts [abstract]. Tallant EA, Holmes CH, Gallagher PE.. In: Proceedings of the 102nd Annual Meeting of the American Association for Cancer Research; 2011 Apr 2-6; Orlando, Florida. Philadelphia (PA): AACR. 2011;():Abstr 4220.

Angiotensin-(1-7) and angiotensin-(1-7) agonists for inhibition of cancer cell growth. Gallagher PE, Tallant EA, Ferrario CM, inventors; Wake Forest University Health Sciences, assignee.. United States patent US 8,034,781. 2011 Oct 11. 2011;():.

Decreased cardiac Ang-(1-7) is associated with salt-induced cardiac remodeling and dysfunction. Varagic J, Ahmad S, Brosnihan KB, Groban L, Chappell MC, Tallant EA, Gallagher PE, Ferrario CM.. Ther Adv Cardiovasc Dis. 2010;4(1):17-25.

Mitogen-activated protein kinase phosphatase-1 (MKP-1) is low in dorsal medulla of hypertensive (mRen2)27 transgenic rats [abstract]. Nautiyal M, Tallant EA, Chappell MC, Diz DI.. FASEB J. 2010;24(1 Meeting Abstracts):955.11.

Angiotensin-(1-7) reduces fibrosis in orthotopic breast tumors. Cook KL, Metheny-Barlow LJ, Tallant EA, Gallagher PE.. Cancer Res. 2010;70(21):8319-8328.

Angiotensin-(1-7) reduces angiotensin II-induced remodeling of the microcirculation [abstract]. Carver KA, Smith TL, Gallagher PE, Tallant EA.. Hypertension. 2010;56(5):e141-e142.

Oxidative stress and low expression of mitogen-activated protein kinase phosphatase-1 (MKP-1) in dorsal medulla of hypertensive (mRen2)27 transgenic rats [abstract]. Nautiyal M, Katakam PV, Busija DW, Gallagher PE, Tallant EA, Chappell MC, Diz DI.. Hypertension. 2010;56(5):e156.

Angiotensin-(1-7) inhibition of human breast tumors with distinct hormone receptor expression results in a differential regulation of AKT [abstract]. Cook KL, Soto PD, Gallagher P, Tallant EA.. Cancer Res. 2009;69(2 Suppl):240S.

Angiotensin-(1-7) inhibits triple negative tumor growth through the inhibition of angiogenesis and a reduction in placental growth factor PIGF [abstract]. Soto-Pantoja DR, Petty WJ, Gallagher PE, Tallant EA.. Cancer Res. 2009;69(2 Suppl):103S.

Angiotensin-(1-7) inhibits tumor angiogenesis in human lung cancer xenografts with a reduction in vascular endothelial growth factor. Soto-Pantoja DR, Menon J, Gallagher PE, Tallant EA.. Mol Cancer Ther. 2009;8(6):1676-1683.

Phase I and pharmacokinetic study of angiotensin-(1-7), an endogenous antiangiogenic hormone. Petty WJ, Miller AA, McCoy TP, Gallagher PE, Tallant EA, Torti FM.. Clin Cancer Res. 2009;15(23):7398-7404.

Angiotensin-(1-7) reduces MAP kinase activity by upregulation of the dual-specificity phosphatase DUSP1 [abstract]. Gallagher PE, Tallant EA.. Hypertension. 2009;54(4):e35.

Angiotensin-(1-7) reduces Ang II-induced cardiac hypertrophy with an associated increase in the dual-specificity phosphatase 1 (DUSP1) [abstract]. Tallant EA, McCollum LT, Gallagher PE.. Hypertension. 2009;54(4):e122.

Phase I study of angiotensin-(1-7), an endogenous antiangiogenic hormone: clinical, pharmacokinetic, and biomarker findings [abstract]. Petty WJ, Miller AA, McCoy TP, Gallagher PE, Tallant EA, Torti FM.. Mol Cancer Ther. 2009;8(12 Suppl 1):B208.

Angiotensin-(1-7), a small molecule inhibitor of glioblastoma growth [abstract]. Lesser GJ, Carver KA, Newton SJ, Tallant EA, Gallagher PE.. J Clin Oncol. 2009;27(15 Suppl):2024.

Injections of angiotensin-converting enzyme 2 inhibitor MLN4760 into nucleus tractus solitarii reduce baroreceptor reflex sensitivity for heart rate control in rats. Diz DI, Garcia-Espinosa MA, Gegick S, Tommasi EN, Ferrario CM, Tallant EA, Chappell MC, Gallagher PE.. Exp Physiol. 2008;93(5):694-700.

Angiotensin-(1-7) reduces lung tumor incidence in a novel bitransgenic Ki-ras G12C mouse model of lung tumorigenesis through a reduction in cyclooxygenase-2 [abstract]. Menon J, Miller MS, Soto-Pantoja DR, Callahan MF, Tallant EA, Gallagher PE.. In: Proceedings of the 99th Annual Meeting of the American Association for Cancer Research; 2008 Apr 12-16; San Diego, CA. Philadelphia (PA): AACR. 2008;():Abstr 4654.

Angiotensin-(1-7) inhibits the growth of human triple negative breast tumors in an orthotopic model [abstract]. Soto-Pantoja DR, Menon J, Gallagher PE, Tallant EA.. In: Proceedings of the 99th Annual Meeting of the American Association for Cancer Research ; 2008 Apr 12-16; San Diego (CA). Philadelphia (PA): AACR. 2008;():Abstr 2416.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Professor, Hypertension

Elisabeth A. Tallant, Ph.D.

Elisabeth A. Tallant, Ph.D.

Assistant Director, Hypertension and Vascular Research Center
Professor, Hypertension
Redox Biology & Medicine Ctr

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