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Janet Austin Tooze, Ph.D.Wake Forest School of Medicine

Janet Austin Tooze, Ph.D.


Clinical Interests

Physical Fitness and Exercise Prescription, Cancer Prevention, Epidemiology, Nutrition

Contact Information

Academic: 336-716-3833 | Department: 336-716-2011


Education & Training

  • A.B., Earlham College, 1990
  • Ph.D., University of Colorado-Boulder, 2000
  • M.P.H., Harvard School of Public Health, 2001
  • Fellowship, Natl Cancer Institute (NIH), 2004


  • Am Statistical Assoc
  • Biometric Society
Janet Austin Tooze, Ph.D.

Janet Austin Tooze, Ph.D.

Professor, Biostatistical Sciences
Office of Women in Medicine and Science

Research Interests

Models, Statistical; Diet; Nutrition Assessment; Survivors; Diet Surveys
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Contact Information

Academic: 336-716-3833 | Department: 336-716-2011


Recent Publications

Whole thorax irradiation of non-human primates induces persistent nuclear damage and gene expression changes in peripheral blood cells. Ghandhi SA, Turner HC, Shuryak I, Dugan GO, Bourland JD, Olson JD, Tooze JA, Morton SR, Batinic-Haberle I, Cline JM, Amundson SA.. PLoS One. 2018;13(1):e0191402.

Contextual and stress process factors associated with head and neck cancer caregivers' physical and psychological well-being. Paek MS, Nightingale CL, Tooze JA, Milliron BJ, Weaver KE, Sterba KR.. Eur J Cancer Care (Engl). 2018;27(2):e12833.

Relationship of sodium intake and blood pressure varies with energy intake: secondary analysis of the DASH (Dietary Approaches to Stop Hypertension)-Sodium trial. Murtaugh MA, Beasley JM, Appel LJ, Guenther PM, McFadden M, Greene T, Tooze JA.. Hypertension. 2018;71(5):858-865.

Tacrolimus levels and correlation to age and weight calculation [abstract]. Seegars MB, Tooze J, Isom S, Anders B, Kennedy L, Rodriguez C.. Biol Blood Marrow Transplant. 2018;24(3 Suppl 1):S337.

Convenient and Live Movement (CALM) for women undergoing breast cancer treatment: challenges and recommendations for internet-based yoga research. Addington EL, Sohl SJ, Tooze JA, Danhauer SC.. Complement Ther Med. 2018;37():77-79.

Hypoalbuminemia is not associated with inferior survival in children with cancer [abstract]. McLean T, Stewart R, Curley T, Dewsnup M, Russell T, Tooze J.. Pediatr Blood Cancer. 2018;65(Suppl 1):815.

Smoking status and symptom burden in surgical head and neck cancer patients. Sterba KR, Garrett-Mayer E, Carpenter MJ, Tooze JA, Hatcher JL, Sullivan C, Tetrick LA, Warren GW, Day TA, Alberg AJ, Weaver KE.. Laryngoscope. 2017;127(1):127-133.

Associations between long chain polyunsaturated fatty acids and cardiovascular lipid risk factors in youth with type 1 diabetes: SEARCH Nutrition Ancillary Study. Couch SC, Crandell J, King I, Peairs A, Shah AS, Dolan LM, Tooze J, Crume T, Mayer-Davis E.. J Diabetes Complications. 2017;31(1):67-73.

Protein intake and mobility limitation in community-dwelling older adults: the Health ABC study. Houston DK, Tooze JA, Garcia K, Visser M, Rubin S, Harris TB, Newman AB, Kritchevsky SB.. J Am Geriatr Soc. 2017;65(8):1705-1711.

Cerebrovascular remodeling and neuroinflammation is a late effect of radiation-induced brain injury in non-human primates. Andrews RN, Metheny-Barlow LJ, Peiffer AM, Hanbury DB, Tooze JA, Bourland JD, Hampson RE, Deadwyler SA, Cline JM.. Radiat Res. 2017;187(5):599-611.

The Short Physical Performance Battery (SPPB) score predicts survival among older adults with acute myeloid leukemia (AML) who have achieved remission [abstract]. Saad MH, Tooze JA, Pardee TS, Williamson J, Kritchevsky S, Ellis LR, Powell BL, Klepin HD.. J Am Geriatr Soc. 2017;65(Suppl 1):S131.

An approach for examining the impact of food group-based sources of nutrients on outcomes with application to PUFAs and LDL. Tooze JA, Crandell JL, Natalie S, Couch SC, Mayer-Davis EJ, Koebnick C, Liese AD.. FASEB J. 2017;31(Suppl 1):788.8.

Tobacco use and surgical outcomes in patients with head and neck cancer. Hatcher JL, Sterba KR, Tooze JA, Day TA, Carpenter MJ, Alberg AJ, Sullivan CA, Fitzgerald NC, Weaver KE.. Head Neck. 2016;38(5):700-706.

Vulnerable characteristics and interest in wellness programs among head and neck cancer caregivers. Nightingale CL, Sterba KR, Tooze JA, Milliron BJ, Tetrick LA, Paek MS, Weaver KE.. Support Care Cancer. 2016;24(8):3437-3445.

Effects of pubertal exposure to dietary soy on estrogen receptor activity in the breast of cynomolgus macaques. Dewi FN, Wood CE, Willson CJ, Register TC, Lees CJ, Howard TD, Huang Z, Murphy SK, Tooze JA, Chou JW, Miller LD, Cline JM.. Cancer Prev Res (Phila Pa). 2016;9(5):385-395.

A population based study of uptake of human papilloma virus (HPV) vaccine in cancer survivors [abstract]. Castellino S, Pleasant K, Poehling K, Tooze J.. Pediatr Blood Cancer. 2016;63(Suppl 1):S54.

Statistical issues related to dietary intake as the response variable in intervention trials. Keogh RH, Carroll RJ, Tooze JA, Kirkpatrick SI, Freedman LS.. Stat Med. 2016;35(25):4493-4508.

The impact of stratification by implausible energy reporting status on estimates of diet-health relationships. Tooze JA, Freedman LS, Carroll RJ, Midthune D, Kipnis V.. Biom J. 2016;58(6):1538-1551.

Effect of intensive chemotherapy on physical, cognitive, and emotional health of older adults with acute myeloid leukemia. Klepin HD, Tooze JA, Pardee TS, Ellis LR, Berenzon D, Mihalko SL, Danhauer SC, Rao AV, Wildes TM, Williamson JD, Powell BL, Kritchevsky SB.. J Am Geriatr Soc. 2016;64(10):1988-1995.

Geriatrics fellowship training and the role of geriatricians in older adult cancer care: a survey of geriatrics fellowship directors. Maggiore RJ, Callahan KE, Tooze JA, Parker IR, Hsu T, Klepin HD.. Gerontol Geriatr Educ. 2016;():.

Process evaluation of a community garden at an urban outpatient clinic. Milliron BJ, Vitolins MZ, Gamble E, Jones R, Chenault MC, Tooze JA.. J Community Health. 2016;42(4):639-648.

Feasibility of a brief yoga intervention for improving acute pain and distress post gynecologic surgery. Sohl SJ, Avis NE, Stanbery K, Tooze JA, Moormann K, Danhauer SC.. Int J Yoga Therap. 2016;26(1):43-47.

Relative validity and reliability of an FFQ in youth with type 1 diabetes. Liese AD, Crandell JL, Tooze JA, Fangman MT, Couch SC, Merchant AT, Bell RA, Mayer-Davis EJ.. Public Health Nutr. 2015;18(3):428-437.

Low-dose CT lung cancer screening practices and attitudes among primary care providers at an academic medical center. Lewis JA, Petty WJ, Tooze JA, Miller DP, Chiles C, Miller AA, Bellinger C, Weaver KE.. Cancer Epidemiol Biomarkers Prev. 2015;24(4):664-670.

Cancer care training content of US Geriatric Medicine Fellowship Programs: a survey of geriatrics fellowship program directors [abstract]. Maggiore R, Callahan K, Parker I, Tooze J, Hsu T, Klepin H.. J Am Geriatr Soc. 2015;63(Suppl 1):S54-S55.

Low 25-hydroxyvitamin D concentrations predict incident depression in well-functioning older adults: the Health, Aging, and Body Composition Study. Williams JA, Sink KM, Tooze JA, Atkinson HH, Cauley JA, Yaffe K, Tylavsky FA, Rubin SM, Simonsick EM, Kritchevsky SB, Houston DK.. J Gerontol A Biol Sci Med Sci. 2015;70(6):757-763.

Protein intake and incident mobility limitations in older adults: the Health ABC Study [abstract]. Houston DK, Tooze JA, Garcia KR, Visser M, Tylavsky FA, Hue TF, Lee JS, Murphy RA, Simonsick EM, Harris TB, Newman AB, Kritchevsky SB.. J Frailty Aging. 2015;4(Suppl 1):30.

Injury patterns associated with hypotension in pediatric trauma patients: a national trauma database review. Gardner AR, Diz DI, Tooze JA, Miller CD, Petty J.. J Trauma Acute Care Surg. 2015;78(6):1143-1148.

The validity of self-reported recent smoking in head and neck cancer surgical patients. Alberg AJ, Worley ML, Tooze JA, Hatcher JL, Carpenter MJ, Day TA, Sullivan CA, Warren GW, Sterba KR, Weaver KE.. Otolaryngol Head Neck Surg. 2015;153(6):990-995.

Sugar-sweetened beverage intake and cardiovascular risk factor profile in youth with type 1 diabetes: application of measurement error methodology in the SEARCH Nutrition Ancillary Study. Liese AD, Crandell JL, Tooze JA, Kipnis V, Bell R, Couch SC, Dabelea D, Crume TL, Mayer-Davis EJ.. Br J Nutr. 2015;114(3):430-438.

Interest in wellness programs among caregivers of head and neck cancer patients [abstract]. Nightingale C, Weaver K, Tooze J, Milliron BJ, Paek MS, Sterba K.. Psychooncology. 2015;24(Suppl 2):189.

Delivery of a vitamin D intervention in homebound older adults using a Meals-on-Wheels program: a pilot study. Houston DK, Tooze JA, Demons JL, Davis BL, Shertzer-Skinner R, Kearsley LB, Kritchevsky SB, Williamson JD.. J Am Geriatr Soc. 2015;63(9):1861-1867.

Addressing current criticism regarding the value of self-report dietary data. Subar AF, Freedman LS, Tooze JA, Kirkpatrick SI, Boushey C, Neuhouser ML, Thompson FE, Potischman N, Guenther PM, Tarasuk V, Reedy J, Krebs-Smith SM.. J Nutr. 2015;145(12):2639-2645.

Feasibility of a symptom-adapted physical activity intervention during induction chemotherapy for older adults with acute myeloid leukemia (AML) [abstract]. Klepin HD, Tooze J, Pardee T, Ellis LR, Berenzon D, Howard D, Demark-Wahnefried W, Mihalko S, Rejeski WJ, Powell BL, Kritchevsky S.. Blood. 2015;126(23):2102.

Goals of care discussions and subsequent health care utilization among adults hospitalized for advanced incurable malignancy [abstract]. Buchanan L, Tooze J, Klepin H, Streer NP.. J Clin Oncol. 2015;33(29 Suppl):46.

Usual dietary intake among female breast cancer survivors is not significantly different from women with no cancer history: results of the National Health and Nutrition Examination Survey, 2003-2006. Milliron BJ, Vitolins MZ, Tooze JA.. J Acad Nutr Diet. 2014;114(6):932-937.

The prognostic importance of polypharmacy in older adults treated for acute myelogenous leukemia (AML). Elliot K, Tooze JA, Geller R, Powell BL, Pardee TS, Ritchie E, Kennedy L, Callahan KE, Klepin HD.. Leuk Res. 2014;38(10):1184-1190.

Low-dose CT lung cancer screening practices and attitudes among primary care providers at an academic medical center [abstract]. Lewis J, Petty WJ, Tooze JA, Miller DP, Chiles C, Miller AA, Weaver KE.. Int J Radiat Oncol Biol Phys. 2014;90(Suppl 5):S7-S8.

Protein intake and lower extremity physical performance in older adults: the Health ABC Study [abstract]. Houston DK, Tooze JA, Garcia KR, Visser M, Tylavsky FA, Newman AB, Harris TB, Kritchevsky SB.. J Nutr Health Aging. 2014;18(6):632.

Protein intake and lower extremity physical performance in older adults: the Health ABC Study [abstract]. Houston DK, Tooze J, Garcia KR, Visser M, Tylavsky FA, Newman AB, Harris TB, Kritchevsky SB.. Gerontologist. 2014;54(Suppl 2):460.

Low 25-hydroxyvitamin D predicts the onset of mobility limitation and disability in community-dwelling older adults: the Health ABC Study. Houston DK, Neiberg RH, Tooze JA, Hausman DB, Johnson MA, Cauley JA, Bauer DC, Shea MK, Schwartz GG, Williamson JD, Harris TB, Kritchevsky SB.. J Gerontol A Biol Sci Med Sci. 2013;68(2):181-187.

African American prostate cancer survivors' treatment decision-making and quality of life. Palmer NR, Tooze JA, Turner AR, Xu J, Avis NE.. Patient Educ Couns. 2013;90(1):61-68.

Geriatric assessment predicts survival for older adults receiving induction chemotherapy for acute myelogenous leukemia. Klepin HD, Geiger AM, Tooze JA, Kritchevsky SB, Williamson JD, Pardee TS, Ellis LR, Powell BL.. Blood. 2013;121(21):4287-4294.

Potential role of community-based healthcare system data in research on survivors of adolescent and young adult cancer. Geiger AM, Castellino SM, Tooze JA, Altschuler A, Month S, Mertens AC, Nekhlyudov L, Greene SM.. J Adolesc Young Adult Oncol. 2013;2(2):53-58.

Isolated head injury is a cause of shock in pediatric trauma patients. Gardner A, Poehling KA, Miller CD, Tooze JA, Petty J.. Pediatr Emerg Care. 2013;29(8):879-883.

A measurement error model for physical activity level as measured by a questionnaire with application to the 1999-2006 NHANES questionnaire. Tooze JA, Troiano RP, Carroll RJ, Moshfegh AJ, Freedman LS.. Am J Epidemiol. 2013;177(11):1199-1208.

Dietary soy effects on mammary gland development during the pubertal transition in nonhuman primates. Dewi FN, Wood CE, Lees CJ, Willson CJ, Register TC, Tooze JA, Franke AA, Cline JM.. Cancer Prev Res (Phila Pa). 2013;6(8):832-842.

An automated system for detecting nonadherence in laboratory testing and monitoring for myelosuppression in patients receiving self-administered oral chemotherapy. Morrell RM, Tooze JA, Harmon MS, Carter AF, DeTroye AT, Lesser GJ.. J Oncol Pract. 2013;9(5):E268-E271.

Multi-profile hidden Markov model for mood, dietary intake, and physical activity in an intervention study of childhood obesity. Ip EH, Zhang Q, Schwartz R, Tooze J, Leng X, Han H, Williamson DA.. Stat Med. 2013;32(19):3314-3331.

Age-related treatment disparities among medicaid beneficiaries with metastatic colorectal cancer. Klepin HD, Tooze JA, Song EY, Geiger AM, Foley KL.. J Gerontol Geriatr Res. 2013;2(4):134.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Professor, Biostatistical Sciences

Clinical Interests

Physical Fitness and Exercise Prescription, Cancer Prevention, Epidemiology, Nutrition

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