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Research

Francis O. Walker, M.D.

Professor, Neurology

Clinical Specialties

Electromyography, Botulinum Toxin

Contact Information

New Patient Appointments: 336-716-WAKE
Returning Patient Appointments: 336-716-4101
Department: 336-716-7548

Education & Training

B.A., Indiana University-Bloomington , 1974
M.D., Indiana University School of Medicine , 1978
Internship, Internal Medicine, U Iowa Hosps & Clinics, 1979
Residency, Neurology, U Iowa Hosps & Clinics, 1981
Fellowship, U Iowa Hosps & Clinics, 1982
Fellowship, University of Michigan Medical School, 1983

Board Certifications

American Board of Psychiatry & Neurology, Neurology
American Board of Psychiatry & Neurology, Neurology, Neuromuscular Medicine

NPI Number

1639155724

Francis O. Walker, M.D.

Professor, Neurology

Contact Information

Academic: 336-716-7548 | Department: 336-716-7548

Recent Publications

Cartwright MS, Kwayisi G, Griffin LP, Sarwal A, Walker FO, Harris JM, Berry MJ, Chahal PS, Morris PE. Quantitative neuromuscular ultrasound in the intensive care unit. Muscle Nerve. 2013;47(2):255-259.

Sarwal A, Walker FO, Cartwright MS. Neuromuscular ultrasound for evaluation of the diaphragm. Muscle Nerve. 2013;47(3):319-329.

Walker FO. Measuring severity and dolor almighty [editorial]. Clin Neurophysiol. 2013;124(3):435-436.

Cartwright MS, Walker FO, Blocker JN, Schulz MR, Arcury TA, Grzywacz JG, Mora D, Chen H, Marin AJ, Quandt SA. The prevalence of carpal tunnel syndrome in Latino poultry-processing workers and other Latino manual workers. J Occup Environ Med. 2012;54(2):198-201.

Mayans D, Cartwright MS, Walker FO. Neuromuscular ultrasonography: quantifying muscle and nerve measurements. Phys Med Rehabil Clin N Am. 2012;23(1):133-148.

Walker FO, Cartwright MS. Neuromuscular ultrasound as a complement to the electrodiagnostic evaluation In: Aminoff MJ, ed. Aminoff's electrodiagnosis in clinical neurology. 6th ed. Edinburgh: Elsevier/Saunders;2012: 367-384.

Strowd RE, Scott B, Walker FO. Black widow spider envenomation, a rare cause of Horner's syndrome. Wilderness Environ Med. 2012;23(2):158-160.

Walker FO, MacDonald JA. Electrically silent muscle visible by ultrasound. J Clin Neuromuscul Dis. 2012;13(3):159-161.

Dorsey ER, Walker F, O'Neill C, Hunt V, et al. Characterization of a large group of individuals with Huntington disease and their relatives enrolled in the COHORT study. PLoS ONE. 2012;7(2):e29522.

Cartwright MS, Hobson-Webb LD, Boon AJ, Alter KE, Hunt CH, Flores VH, Werner RA, Shook SJ, Thomas TD, Primack SJ, Walker FO. Evidence-based guideline: neuromuscular ultrasound for the diagnosis of carpal tunnel syndrome. Muscle Nerve. 2012;46(2):287-293.

Walker FO, Lyles MF, Li Z. Sheet fitting palsy. J Clin Neuromuscul Dis. 2012;14(1):48-50.

Walker FO, Cartwright MS, eds. In: Neuromuscular ultrasound. Philadelphia: Elsevier/Saunders;2011: .

Walker FO. Basic principles of ultrasound In: Walker FO, Cartwright MS, eds. Neuromuscular ultrasound. Philadelphia: Elsevier/Saunders;2011: 1-23.

Walker FO. Interventional ultrasound In: Walker FO, Cartwright MS, eds. Neuromuscular ultrasound. Philadelphia: Elsevier/Saunders;2011: 150-165.

Walker FO. Future directions in neuromuscular ultrasound In: Walker FO, Cartwright MS, eds. Neuromuscular ultrasound. Philadelphia: Elsevier/Saunders;2011: 177-186.

Cartwright MS, Yoon JS, Lee KH, Deal N, Walker FO. Diagnostic ultrasound for traumatic radial neuropathy. Am J Phys Med Rehabil. 2011;90(4):342-343.

Walker FO, Cartwright MS. Neuromuscular ultrasound: emerging from the twilight [editorial]. Muscle Nerve. 2011;43(6):777-779.

Cartwright MS, White DL, Demar S, Wiesler ER, Sarlikiotis T, Chloros GD, Yoon JS, Won SJ, Molnar JA, Defranzo AJ, Walker FO. Median nerve changes following steroid injection for carpal tunnel syndrome. Muscle Nerve. 2011;44(1):25-29.

Wetzel HH, Gehl CR, Dellefave-Castillo L, Schiffman JF, Shannon KM, Paulsen JS, Hunt V, Walker F, et al. Suicidal ideation in Huntington disease: the role of comorbidity. Psychiatry Res. 2011;188(3):372-376.

Cartwright MS, Walker FO, Griffin LP, Caress JB. Peripheral nerve and muscle ultrasound in amyotrophic lateral sclerosis. Muscle Nerve. 2011;44(3):346-351.

Pankratz N, Dumitriu A, Hetrick KN, Sun M, Latourelle JC, Wilk JB, Halter C, Doheny KF, Gusella JF, Nichols WC, Myers RH, Foroud T, DeStefano AL, Walker F, Hunt V, O'Neill C, et al. Copy number variation in familial Parkinson disease. PLoS ONE. 2011;6(8):e20988.

Latourelle JC, Hendricks AE, Pankratz N, Wilk JB, Halter C, Nichols WC, Gusella JF, Destefano AL, Myers RH, Foroud T, Walker F, Hunt V, O'Neill C, et al. Genomewide linkage study of modifiers of LRRK2-related Parkinson's disease. Mov Disord. 2011;26(11):2039-2044.

Kieburtz K, McDermott MP, Voss TS, Corey-Bloom J, Deuel LM, Dorsey ER, Factor S, Geschwind MD, Hodgeman K, Walker F, et al. A randomized, placebo-controlled trial of latrepirdine in Huntington disease. Arch Neurol. 2010;67(2):154-160.

Walker FO. Does hereditary hemochromatosis influence the age of onset of Huntington's disease? [letter]. Mov Disord. 2010;25(7):946.

Yoon JS, Walker FO, Cartwright MS. Ulnar neuropathy with normal electrodiagnosis and abnormal nerve ultrasound. Arch Phys Med Rehabil. 2010;91(2):318-320.

Anderson KE, Gehl CR, Marder KS, Beglinger LJ, Paulsen JS, Hunt V, Walker F, et al. Comorbidities of obsessive and compulsive symptoms in Huntington's disease. J Nerv Ment Dis. 2010;198(5):334-338.

Beglinger LJ, O'Rourke JJ, Wang C, Langbehn DR, Duff K, Paulsen JS, Hedges P, McCusker E, Hunt V, Walker F, et al. Earliest functional declines in Huntington disease. Psychiatry Res. 2010;178(2):414-418.

Walker FO, Alter KE, Boon AJ, Cartwright MS, Flores VH, Hobson-Webb LD, Hunt CH, Primack SJ, Shook SJ. Qualifications for practitioners of neuromuscular ultrasound: position statement of the American Association of Neuromuscular and Electrodiagnostic Medicine. Muscle Nerve. 2010;42(3):442-444.

Hyson HC, Kieburtz K, Shoulson I, McDermott M, Ravina B, de Blieck EA, Cudkowicz ME, Ferrante RJ, Walker F, Hunt V, et al. Safety and tolerability of high-dosage coenzyme Q10 in Huntington's disease and healthy subjects. Mov Disord. 2010;25(12):1924-1928.

Walker FO. Assessing muscle function at the bedside: can we do better? [editorial]. Muscle Nerve. 2010;42(4):466-468.

Quaid KA, Swenson MM, Sims SL, Harrison JM, Moskowitz C, Stepanov N, Suter GW, Caress J, Walker F, Hunt V, et al. What were you thinking?: individuals at risk for Huntington Disease talk about having children. J Genet Couns. 2010;19(6):606-617.

Schwarz H, Hickey C, Zimmerman C, Mazzoni P, Moskowitz C, Rosas D, McCall M, Sanchez-Ramos J, Perlmutter J, Walker F, et al. A futility study of minocycline in Huntington's disease. Mov Disord. 2010;25(13):2219-2224.

Simon DK, Pankratz N, Kissell DK, Pauciulo MW, Halter CA, Rudolph A, Pfeiffer RF, Nichols WC, Foroud T, Walker F, Hunt V, O'Neill C, et al. Maternal inheritance and mitochondrial DNA variants in familial Parkinson's disease. BMC Med Genet. 2010;11():53.

Cartwright MS, Shin HW, Passmore LV, Walker FO. Ultrasonographic reference values for assessing the normal median nerve in adults. J Neuroimaging. 2009;19(1):47-51.

Chloros GD, Cartwright MS, Walker FO, Wiesler ER. Sonography and electrodiagnosis in carpal tunnel syndrome diagnosis, an analysis of the literature [letter]. Eur J Radiol. 2009;71(1):141-143.

Cartwright MS, Brown ME, Eulitt P, Walker FO, Lawson VH, Caress JB. Diagnostic nerve ultrasound in Charcot-Marie-Tooth disease type 1B. Muscle Nerve. 2009;40(1):98-102.

Walker FO. Reflections: neurology and the humanities. The anatomy of melancholy. Neurology. 2009;73(6):483-485.

Frank S, Walker F, Hunt VP, et al. Tetrabenazine as anti-chorea therapy in Huntington disease: an open-label continuation study. Huntington Study Group/TETRA-HD Investigators. BMC Neurol. 2009;9():62.

Latourelle JC, Pankratz N, Dumitriu A, Wilk JB, Goldwurm S, Pezzoli G, Mariani CB, DeStefano AL, Halter C, Gusella JF, Nichols WC, Myers RH, Foroud T, Walker F, Hunt V, O'Neill C, et al. Genomewide association study for onset age in Parkinson disease. BMC Med Genet. 2009;10():98.

Pankratz N, Wilk JB, Latourelle JC, DeStefano AL, Halter C, Pugh EW, Doheny KF, Gusella JF, Nichols WC, Foroud T, Myers RH, Walker F, Hunt V, O'Neill C, et al. Genomewide association study for susceptibility genes contributing to familial Parkinson disease. Hum Genet. 2009;124(6):593-605.

Cartwright MS, Passmore LV, Yoon J-S, Brown ME, Caress JB, Walker FO. Cross-sectional area reference values for nerve ultrasonography. Muscle Nerve. 2008;37(5):566-571.

Frank S, Ondo W, Fahn S, Hunter C, Oakes D, Plumb S, Marshall F, Shoulson I, Walker F, Hunt V, et al. A study of chorea after tetrabenazine withdrawal in patients with Huntington disease. Clin Neuropharmacol. 2008;31(3):127-133.

Yoon JS, Hong S-J, Kim B-J, Kim SJ, Kim JM, Walker FO, Cartwright MS. Ulnar nerve and cubital tunnel ultrasound in ulnar neuropathy at the elbow. Arch Phys Med Rehabil. 2008;89(5):887-889.

Yoon JS, Walker FO, Cartwright MS. Ultrasonographic swelling ratio in the diagnosis of ulnar neuropathy at the elbow. Muscle Nerve. 2008;38(4):1231-1235.

Walker FO. Huntington's disease. Lancet. 2007;369(9557):218-228.

Cartwright MS, Shin HW, Passmore LV, Walker FO. Ultrasonographic findings of the normal ulnar nerve in adults. Arch Phys Med Rehabil. 2007;88(3):394-396.

Walker FO. Huntington's disease. Semin Neurol. 2007;27(2):143-150.

Beglinger LJ, Langbehn DR, Duff K, Stierman L, Black DW, Nehl C, Anderson K, Penziner E, Hunt V, Walker F, et al. Probability of obsessive and compulsive symptoms in Huntington's disease. Biol Psychiatry. 2007;61(3):415-418.

Nichols WC, Marek DK, Pauciulo MW, Pankratz N, Halter CA, Rudolph A, Shults CW, Wojcieszek J, Walker F, Hunt V, et al. R1514Q substitution in Lrrk2 is not a pathogenic Parkinson's disease mutation. Mov Disord. 2007;22(2):254-257.

Duff K, Beglinger LJ, Schultz SK, Moser DJ, McCaffrey RJ, Haase RF, Westervelt HJK, Langbehn DR, Walker F, Hunt V, et al. Practice effects in the prediction of long-term cognitive outcome in three patient samples: a novel prognostic index. Arch Clin Neuropsychol. 2007;22(1):15-24.

Langbehn DR, Paulsen JS, Hedges P, McCusker E, Pearce S, Trent R, Abwender D, Como P, Hunt V, Walker F, et al. Predictors of diagnosis in Huntington disease. Neurology. 2007;68(20):1710-1717.

Cartwright MS, Chloros GD, Walker FO, Wiesler ER, Campbell WW. Diagnostic ultrasound for nerve transection. Muscle Nerve. 2007;35(6):796-799.

Walker FO. The four horsemen of the oscilloscope: dynamic ultrasound, static ultrasound, electromyography and nerve conduction studies [editorial]. Clin Neurophysiol. 2007;118(6):1177-1178.

Smith R, Ferrario C, Walker F. Number of antihypertensive agents required to achieve goal blood pressure with an Olmesartan Medoxomil vs Atenolol based regimen [abstract]. J Hypertens. 2007;25(Suppl 2):S240-S241.

Yoon JS, Kim BJ, Kim SJ, Kim JM, Sim KH, Hong SJ, Walker FO, Cartwright MS. Ultrasonographic measurements in cubital tunnel syndrome. Muscle Nerve. 2007;36(6):853-855.

Ginn SD, Cartwright MS, Chloros GD, Walker FO, Yoon J-S, Brown ME, Wiesler ER. Ultrasound in the diagnosis of a median neuropathy in the forearm: case report. J Brachial Plex Peripher Nerve Inj. 2007;2():article 23.

Wiesler ER, Chloros GD, Cartwright MS, Shin HW, Walker FO. Ultrasound in the diagnosis of ulnar neuropathy at the cubital tunnel. J Hand Surg [Am]. 2006;31(7):1088-1093.

Cartwright MS, Chloros GD, Walker FO, Wiesler ER, Campbell WW. Diagnostic ultrasound for nerve transection [abstract]. Ann Neurol. 2006;60(5):636.

Shoulson I, Kieburtz K, Oakes D, Kayson E, Zhao H, Shinaman A, Romer M, Caress J, Walker F, Hunt V, et al. At risk for Huntington disease: the PHAROS (Prospective Huntington At Risk Observational Study) Cohort enrolled. Arch Neurol. 2006;63(7):991-996.

Pankratz N, Pauciulo MW, Elsaesser VE, Marek DK, Halter CA, Wojcieszek J, Rudolph A, Shults CW, Walker F, Hunt V, et al. Mutations in DJ-I are rare in familial Parkinson disease. Neurosci Lett. 2006;408(3):209-213.

Pankratz N, Pauciulo MW, Elsaesser VE, Marek DK, Halter CA, Rudolph A, Shults CW, Foroud T, Walker F, Hunt V, et al. Mutations in LRRK2 other than G2019S are rare in a North American-based sample of familial Parkinson's disease. Mov Disord. 2006;21(12):2257-2260.

Walker FO. Autonomic testing In: Kimura J, ed. Peripheral nerve diseases. Edinburgh: Elsevier;2006: 487-509.