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Hao Wang, M.D., Ph.D.Wake Forest School of Medicine

Hao Wang, M.D., Ph.D.

Assistant Professor,

Contact Information

Academic: 336-716-2943

Email: haowang@wakehealth.edu

Education & Training

  • Doctor of Medicine, Shandong Medical University-China, 1990
  • M.S., Xi'an Jiaotong Univeristy, 1996
  • Ph.D., First Teaching Hosp of Shandong University, 1999
  • Fellowship, Medicine, University Ottawa School Medic, 2002
  • Residency, Medicine, 1st Teachx Hosp Shandong Univ, 2003
Hao Wang, M.D., Ph.D.

Hao Wang, M.D., Ph.D.

Assistant Professor, Anesthesiology
Molecular Medicine

Contact Information

Academic: 336-716-2943

Email: haowang@wakehealth.edu

Recent Publications

Mast cell inhibition attenuates cardiac remodeling and diastolic dysfunction in middle-aged, ovariectomized Fischer 344 x Brown Norway rats. Wang H, da Silva J, Alencar A, Zapata-Sudo G, Lin MS, Sun X, Ahmad S, Ferrario CM, Groban L.. J Cardiovasc Pharmacol. 2016;68(1):49-57.

Effect of age, estrogen status, and late-life GPER activation on cardiac structure and function in the Fischer344xBrown Norway female rat. Alencar AK, da Silva JS, Lin M, Silva AM, Sun X, Ferrario CM, Cheng C, Sudo RT, Zapata-Sudo G, Wang H, Groban L.. J Gerontol A Biol Sci Med Sci. 2016;():.

Activation of GPR30 improves exercise capacity and skeletal muscle strength in senescent female Fischer344 x Brown Norway rats. Wang H, Alencar A, Lin M, Sun X, Sudo RT, Zapata-Sudo G, Lowe DA, Groban L.. Biochem Biophys Res Commun. 2016;475(1):81-86.

Intracrine angiotensin II functions originate from noncanonical pathways in the human heart. Ferrario CM, Ahmad S, Varagic J, Cheng CP, Groban L, Wang H, Collawn JF, Dell'Italia LJ.. Am J Physiol Heart Circ Physiol. 2016;311(2):H404-H414.

Cardiomyocyte-specific deletion of the G protein-coupled estrogen receptor (GPER) leads to left ventricular dysfunction and adverse remodeling: a sex-specific gene profiling analysis. Wang H, Sun X, Chou J, Lin M, Ferrario CM, Zapata-Sudo G, Groban L.. Biochim Biophys Acta. 2016;():.

GPR30 decreases cardiac chymase/angiotensin II by inhibiting local mast cell number. Zhao Z, Wang H, Lin M, Groban L.. Biochem Biophys Res Commun. 2015;459(1):131-136.

Activation of GPR30 inhibits cardiac fibroblast proliferation. Wang H, Zhao Z, Lin M, Groban L.. Mol Cell Biochem. 2015;405(1-2):135-148.

Differential expression of the angiotensin-(1-12)/chymase axis in human atrial tissue. Nagata S, Varagic J, Kon ND, Wang H, Groban L, Simington SW, Ahmad S, Dell'Italia LJ, VonCannon JL, Deal D, Ferrario CM.. Ther Adv Cardiovasc Dis. 2015;9(4):168-180.

Augmentation of autophagy by atorvastatin via Akt/mTOR pathway in spontaneously hypertensive rats. Wang W, Wang H, Geng QX, Wang HT, Miao W, Cheng B, Zhao D, Song GM, Leanne G, Zhao Z.. Hypertens Res. 2015;38(12):813-820.

Chronic activation of GPR30 attenuates diastolic dysfunction in oophorectomized senescent rats [abstract]. Groban L, Kardec A, Wang H, da Silva J, Lin MS, Sun X.. In: Abstracts of the 2015 Annual Meeting of the American Society of Anesthesiologists (ASA); 2015 Oct 24-28; San Diego (CA). 2015;():A1265.

Mast cell inhibition attenuates cardiac remodeling and diastolic dysfunction in ovariectomized BNF344 female rats [abstract]. Groban L, Wang H, da Silva J, Kardec A, Lin MS, Sun X.. In: Abstracts of the 2015 Annual Meeting of the American Society of Anesthesiologists (ASA); 2015 Oct 24-28; San Diego (CA). 2015;():A1273.

Late-life activation of GPR30 by G1 reverses diastolic dysfunction in senescent BNF344 female rats [abstract]. Kardec A, Wang H, da Silva J, Lin M, Sun X, Groban L.. Gerontologist. 2015;55(Suppl 2):68.

GPR30 activation improves exercise capacity and skeletal muscle function in senescent female F344BN rats [abstract]. Wang H, Kardec A, Lin M, Sun X, Groban L.. Gerontologist. 2015;55(Suppl 2):105.

Late-life activation of GPR30 by G1 reverses diastolic dysfunction in senescent Fischer344 x Brown Norway female rats [abstract]. Alencar A, Wang H, de Silva J, Lin M, Sun XM, Groban L.. Circ Res. 2015;117(Suppl 1):A351.

Mast cell inhibition attenuates cardiac remodeling and diastolic dysfunction in ovariectomized female Fischer344.Brown Norway Rats [abstract]. Wang H, da Silva J, Alencar A, Lin M, Sun XM, Groban L.. Circ Res. 2015;117(Suppl 1):353.

Mast cell inhibition attenuates cardiac remodeling and diastolic dysfunction in ovariectomized BNF344 female rats [abstract]. Wang H, Da Silva J, Kardec A, Lin M, Sun X, Groban L.. Gerontologist. 2015;55(Suppl 2):69.

Involvement of chemokine receptor Cxcr3 and its ligands Cxcl9 and Cxcl10 in the development of chronic obstructive pulmonary disease [abstract]. Shi ZH, Yan Y, Wang H, Wang L, Feng J, Li Y.. Am J Respir Crit Care Med. 2015;191():A2885.

Impairment of myocardial mitochondria in viral myocardial disease and its reflective window in peripheral cells. Wei J, Gao DF, Wang H, Yan R, Liu ZQ, Yuan ZY, Liu J, Chen MX.. PLoS One. 2014;9(12):e116239.

Hemodynamic and hormonal changes to dual Renin-Angiotensin system inhibition in experimental hypertension. Moniwa N, Varagic J, Ahmad S, Voncannon JL, Simington SW, Wang H, Groban L, Brosnihan KB, Nagata S, Kato J, Kitamura K, Gomez RA, Lopez ML, Ferrario CM.. Hypertension. 2013;61(2):417-424.

Calreticulin-STAT3 signaling pathway modulates mitochondrial function in a rat model of furazolidone-induced dilated cardiomyopathy. Zhang M, Wei J, Shan H, Wang H, Zhu Y, Xue J, Lin L, Yan R.. PLoS One. 2013;8(6):e66779.

Characterization of the cardiac renin angiotensin system in oophorectomized and estrogen-replete mRen2.Lewis rats. Wang H, Jessup JA, Zhao Z, Da Silva J, Lin M, Macnamara LM, Ahmad S, Chappell MC, Ferrario CM, Groban L.. PLoS One. 2013;8(10):e76992.

Estrogen replacement downregulates cardiac angiotensin II in an ACE-independent manner in oophorectomized mRen2.Lewis rats [abstract]. Groban L, Wang H, Zhao Z, Jessup J, Lin M, MacNamara L, Ferrario CM.. In: Abstracts of the 2013 Annual Meeting of the American Society of Anesthesiologists (ASA); 2013 Oct 12-16; San Francisco (CA). 2013;():A5002.

Estrogen replacement downregulates cardiac angiotensin II in an ACE-independent manner in oophorectomized mRen2.Lewis rats [abstract]. Wang H, Zhao Z, Jessup J, Lin M, MacNamara L, Ahmad S, Ferrario C, Groban L.. Circ Res. 2013;113(4 Suppl):A086.

Differential expression of angiotensin-(1-12)/chymase in human atrial tissue [abstract]. Nagata S, Varagic J, Simington SW, Ahmad S, VonCannon JL, Wang H, Groban L, Kon ND, Dell'Italia LJ, Ferrario CM.. Hypertension. 2013;62(3 Suppl):629.

Does cardiac ang-(1-12) have a role in sex-specific heart disease? [abstract]. Nagata S, Varagic J, Simington SW, Ahmad S, VonCannon JL, Wang H, Kon ND, Dell'Italia LJ, Ferrario CM, Groban L.. Hypertension. 2013;62(3 Suppl):632.

Activation of GPR30 attenuates diastolic dysfunction and left ventricle remodelling in oophorectomized mRen2.Lewis rats. Wang H, Jessup JA, Lin MS, Chagas C, Lindsey SH, Groban L.. Cardiovasc Res. 2012;94(1):96-104.

Differential effects of late-life initiation of low-dose enalapril and losartan on diastolic function in senescent Fischer 344 x Brown Norway male rats. Groban L, Lindsey S, Wang H, Lin MS [sic] [Lin MR], Kassik KA, Machado FS, Carter CS.. Age (Dordr). 2012;34(4):831-843.

Low glial angiotensinogen improves body habitus, diastolic function, and exercise tolerance in aging male rats. Groban L, Wang H, Machado FSM, Trask AJ, Kritchevsky SB, Ferrario CM, Diz DI.. Cardiovasc Endocrinol. 2012;1(3):49-58.

Dedicated emergency department ultrasound rotation improves residents' ultrasound knowledge and interpretation skills. Mahler SA, Swoboda TK, Wang H, Arnold TC.. J Emerg Med. 2012;43(1):129-133.

Neuronal nitric oxide synthase inhibition improves diastolic function and reduces oxidative stress in ovariectomized mRen2.Lewis rats. Jessup JA, Zhang L, Chen AF, Presley TD, Kim-Shapiro DB, Chappell MC, Wang H, Groban L.. Menopause. 2011;18(6):698-708.

Tetrahydrobiopterin restores diastolic function and attenuates superoxide production in ovariectomized mRen2.Lewis rats. Jessup JA, Zhang L, Presley TD, Kim-Shapiro DB, Wang H, Chen AF, Groban L.. Endocrinology. 2011;152(6):2428-2436.

Attenuation of salt-induced cardiac remodeling and diastolic dysfunction by the GPER agonist G-1 in female mRen2.Lewis rats. Jessup JA, Lindsey SH, Wang H, Chappell MC, Groban L.. PLoS ONE. 2010;5(11):e15433.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Assistant Professor, Anesthesiology

Hao Wang, M.D., Ph.D.

Hao Wang, M.D., Ph.D.

Assistant Professor, Anesthesiology
Molecular Medicine

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