Profile

Jeffrey L. Weiner, Ph.D.Wake Forest Baptist Health

Jeffrey L. Weiner, Ph.D.

Professor,

Contact Information

Academic: 336-716-8692 | Department: 336-716-8692

Email: jweiner@wakehealth.edu

Additional Languages

French

Education & Training

  • Ph.D., University Toronto Med-Canada , 1994
  • B.S., University Toronto Med-Canada , 1988
  • M.Sc., University Toronto Med-Canada , 1990
  • Fellowship, U Colorado Hlth Sci Ctr, 1998

Memberships

  • Research Society On Alcoholism
  • Int Soc for Biomed Res on Alco
  • Society for Neuroscience
Jeffrey L. Weiner, Ph.D.Wake Forest Baptist Health

Jeffrey L. Weiner, Ph.D.

Professor, Physiology & Pharmacology
Institute for Regenerative Medicine

Research Interests

mental disorders/psychiatry/ps, neurosciences/behavior

Contact Information

Academic: 336-716-8692 | Department: 336-716-8692

Email: jweiner@wakehealth.edu

Recent Publications

Butler TR, Chappell AM, Weiner JL. Effect of beta3 adrenoceptor activation in the basolateral amygdala on ethanol seeking behaviors. Psychopharmacology (Berl). 2014;231(1):293-303.

Butler TR, Ariwodola OJ, Weiner JL. The impact of social isolation on HPA axis function, anxiety-like behaviors, and ethanol drinking. Front Integr Neurosci. 2014;7():102.

Rau AR, Ariwodola OJ, Weiner JL. Presynaptic adenosine A(1) receptors modulate excitatory transmission in the rat basolateral amygdala. Neuropharmacology. 2014;77():465-474.

Chappell AM, Carter E, McCool BA, Weiner JL. Adolescent rearing conditions influence the relationship between initial anxiety-like behavior and ethanol drinking in male Long Evans rats. Alcohol Clin Exp Res. 2013;37(Suppl 1):E394-E403.

Abrahao KP, Ariwodola OJ, Butler TR, Rau AR, Skelly MJ, Carter E, Alexander NP, McCool BA, Souza-Formigoni ML, Weiner JL. Locomotor sensitization to ethanol impairs NMDA receptor-dependent synaptic plasticity in the nucleus accumbens and increases ethanol self-administration. J Neurosci. 2013;33(11):4834-4842.

Yorgason JT, Espana RA, Konstantopoulos JK, Weiner JL, Jones SR. Enduring increases in anxiety-like behavior and rapid nucleus accumbens dopamine signaling in socially isolated rats. Eur J Neurosci. 2013;37(6):1022-1031.

Grinevich VP, Bass CE, Gioia D, Chappell AM, Bonin KD, Weiner JL, Budygin EA. Preliminary evidence that optogenetic activation of VTA dopamine cells inhibits alcohol self-administration in male Long Evans rats [abstract]. Alcohol Clin Exp Res. 2013;37(Suppl 2):229A.

Molina DP, Ariwodola OJ, Linville C, Sonntag WE, Weiner JL, Brunso-Bechtold JK, Adams MM. Growth hormone modulates hippocampal excitatory synaptic transmission and plasticity in old rats. Neurobiol Aging. 2013;33(9):1938-1949.

Abrahao KP, Souza-Formigoni MLO, McCool BA, Camirini R, Weiner JL. Behavioral sensitization to ethanol has bidirectional effects on MGLUR1/5 dependent long-term depression in the nucleus accumbens core and shell [abstract]. Alcohol Clin Exp Res. 2013;37(Suppl 2):120A.

Butler TR, Carter E, Weiner JL. Developmental corticosterone levels and anxiety-like behavior in high and low drinking rats [abstract]. Alcohol Clin Exp Res. 2013;37(Suppl 2):234A.

Karkhanis AN, Konstantopoulos J, Locke J, Weiner JL, Jones SR. Social isolation rearing increases dopamine and norepinephrine responses to ethanol and K-opioid receptor activity in nucleus accumbens [abstract]. Alcohol Clin Exp Res. 2013;37(Suppl 2):240A.

Rau AR, Ariwodola OJ, Chappell AM, Carter E, Weiner JL. Adenosinergic signaling modulates basolateral amygdala glutamatergic synaptic transmission and reduces ethanol drinking [abstract]. Alcohol Clin Exp Res. 2013;37(Suppl 2):181A.

Skelly MJ, Carter ES, Ariwodola OJ, Weiner JL. Preliminary evidence that adolescent social isolation disrupts inhibitory signaling at lateral paracapsular synapses in the rat basolateral amygdala [abstract]. Alcohol Clin Exp Res. 2013;37(Suppl 2):180A.

Weiner JL, Chappell AM, Carter E, Yorgason J, Jones SR, McCool BA. Adolescent social isolation increases behavioral and neurobiological risk factors of alcoholism in male Long Evans rats [abstract]. Alcohol Clin Exp Res. 2013;37(Suppl 2):299A.

Molina DP, Ariwodola OJ, Weiner JL, Brunso-Bechtold JK, Adams MM. Growth hormone and insulin-like growth factor-I alter hippocampal excitatory synaptic transmission in young and old rats. Age (Dordr). 2013;35(5):1575-1587.

Bass CE, Grinevich VP, Gioia D, Day-Brown JD, Bonin KD, Stuber GD, Weiner JL, Budygin EA. Optogenetic stimulation of VTA dopamine neurons reveals that tonic but not phasic patterns of dopamine transmission reduce ethanol self-administration. Front Behav Neurosci. 2013;7():173.

Molina DP, Ariwodola OJ, Linville C, Sonntag WE, Weiner JL, Brunso-Bechtold JK, Adams MM. Growth hormone modulates hippocampal excitatory synaptic transmission and plasticity in old rats. Neurobiol Aging. 2012;33(9):1938-1949.

Butler TR, Chappell AM, Weiner JL. Activation of beta 3 adrenoceptors in the basolateral amygdala reduces ethanol drinking behaviors in male Long Evans rats [abstract]. Alcohol Clin Exp Res. 2012;36(Suppl 1):17A.

Rau AR, Ariwodola OJ, Carter E, Chappell AM, Weiner JL. Adenosine signaling modulates excitibility in the amygdala and is altered in a rodent model of early life stress that increases ethanol drinking [abstract]. Alcohol Clin Exp Res. 2012;36(Suppl 1):104A.

Skelly MJ, Chappell AM, Weiner JL. Social isolation disrupts extinction of fear learning and enhances adrenoceptor antagonist-mediated inhibition of ethanol drinking in Long Evans rats [abstract]. Alcohol Clin Exp Res. 2012;36(Suppl 1):115A.

Chappell AM, Carter E, Yorgason JT, Jones SR, McCool BA, Weiner JL. Juvenile social isolation in rats increases behavioral and neurobiological risk factors of alcoholism [abstract]. Alcohol Clin Exp Res. 2012;36(Suppl 2):51A.


Weiner J. Identification of a novel GABAergic circuit in the basolateral amygdala that may contribute to alcohol's anxiolytic effects [abstract]. Alcohol. 2011;45(3):269.

Abrahao KP, Souza-Formigoni MLO, Weiner JL. Decrease in accumbal NMDA receptor-mediated excitatory transmission is associated with high levels of behavioral sensitization to ethanol [abstract]. Alcohol Clin Exp Res. 2011;35(6 Suppl):57A.

Carter E, Chappell AM, Weiner JL. Effect of housing conditions on anxiety-like behaviors and ethanol drinking in adolescent and adult Long-Evans rats [abstract]. Alcohol Clin Exp Res. 2011;35(6 Suppl):54A.

Rau AR, Ariwodola OJ, Weiner JL. Effect of stimulation frequency on ethanol enhancement of hippocampal gabaergic synaptic inhibition [abstract]. Alcohol Clin Exp Res. 2011;35(6 Suppl):62A.

Weiner JL, Silberman Y, Ariwodola OJ, Chappell AM, Carter E. Treatment of alcohol use disorders? [abstract]. Alcohol Clin Exp Res. 2011;35(6 Suppl):305A.

Silberman Y, Ariwodola OJ, Chappell AM, Yorgason JT, Weiner JL. Lateral paracapsular GABAergic synapses in the basolateral amygdala contribute to the anxiolytic effects of beta 3 adrenoceptor activation. Neuropsychopharmacology. 2010;35(9):1886-1896.

Weiner JL, Royal R, Chappell AM, Carter E. Effect of juvenile social isolation on anxiety-like behaviors and intermittent ethanol self-administration in male Long-Evans rats [abstract]. Alcohol Clin Exp Res. 2010;34(8 Suppl):99A.

Silberman Y, Ariwodola OJ, Weiner JL. Analysis of unitary IPSCS confirms distinct mechanisms of ethanol action at local and paracapsular GABAergic synapses in the rat basolateral amygdala [abstract]. Alcohol Clin Exp Res. 2010;34(6 Suppl 2):196A.

Silberman Y, Ariwodola OJ, Chappell AM, Weiner JL. Identification of a novel GABAergic circuit in the basolateral amygdala that may contribute to alcohol's anti-anxiety effects [abstract]. Alcohol Clin Exp Res. 2010;34(6 Suppl 2):279A.


Carter ES, Chappell AM, Jones SR, Weiner JL. Effect of oral adolescent methylphenidate treatment and withdrawal on ethanol drinking and locomotor response to psychostimulants [abstract]. Alcohol Clin Exp Res. 2009;33(6 Special Issue):98A.

Chappell AM, Weiner JL. Relationship between intermittent and operant ethanol self-administration in male Long-Evans rats [abstract]. Alcohol Clin Exp Res. 2009;33(6 Special Issue):221A.

Silberman Y, Ariwodola OJ, Yorgason JT, Chappell AM, Weiner JL. Basolateral amygdala paracapsular cells may contribute to the anti-anxiety effects of B3-adrenoceptor agonists: implications for ethanol actions [abstract]. Alcohol Clin Exp Res. 2009;33(6 Special Issue):83A.

Silberman Y, Ariwodola OJ, Yorgason JT, Weiner JL. Beta 1-adrenoceptors are required for ethanol potentiation of lateral paracapsular gabaergic synapses in the rat basolateral amygdala [abstract]. Alcohol Clin Exp Res. 2009;33(6 Special Issue):150A.

Molina DP, Weiner JL, Ariwodola OJ, Adams MM, Brunso-Bechtold JK. Age-related alterations in GH and IGF-I signaling cascade elements in Fisher 344 x Brown Norway rats [abstract]. Soc Neurosci Abstr. 2009;2009(Neuroscience Meeting Planner):.

Silberman Y, Bajo M, Chappell AM, Christian DT, Cruz M, Diaz MR, Kash T, Lack AK, McCool BA, Weiner JL, et al. Neurobiological mechanisms contributing to alcohol-stress-anxiety interactions. Alcohol. 2009;43(7):509-519.

Silberman Y, Shi L, Brunso-Bechtold JK, Weiner JL. Distinct mechanisms of ethanol potentiation of local and paracapsular GABAergic synapses in the rat basolateral amygdala. J Pharmacol Exp Ther. 2008;324(1):251-260.

Chappell AM, Jones SR, Weiner JL. Effect of adolescent methylphenidate treatment on ethanol self-administration in male Long-Evans rats [abstract]. Alcohol Clin Exp Res. 2008;32(6 Suppl 1):220A.

Silberman Y, Weiner JL. Acute effects of ethanol on local and paracapsular GABAergic synapses in the rat basolateral amygdala [abstract]. Alcohol. 2008;42(4):314.

Silberman Y, Weiner JL. Distinct mechanisms underlying ethanol potentiation of two inhibitory pathways in the rat basolateral amygdala [abstract]. Alcohol. 2008;42(4):330.

Silberman Y, Weiner JL. Local and paracapsular GABAergic synapses in the rat basolateral amygdala display different GABAb autoreceptor properties [abstract]. Alcohol Clin Exp Res. 2008;32(6 Suppl 1):27A.

Weiner JL, Ariwodola OJ, Jones KM, Chappell AM, Werner DF, Homanics GE. Paradoxical increases in behavioral and synaptic sensitivity to ethanol in genetically-engineered mice with ethanol-insensitive alphal GABAa receptors [abstract]. Alcohol. 2008;42(4):330.

Molina DP, Weiner JL, Ariwodola SJ, Sonntag WE, Adams MM, Brunso-Bechtold JK. Effect of growth hormone (GH) supplementation on age-related changes in excitatory synaptic transmission in CA1 [abstract]. Soc Neurosci Abstr. 2008;2008(Neuroscience Meeting Planner):.

Lack AK, Ariwodola OJ, Chappell AM, Weiner JL, McCool BA. Ethanol inhibition of kainate receptor-mediated excitatory neurotransmission in the rat basolateral nucleus of the amygdala. Neuropharmacology. 2008;55(5):661-668.


Ariwodola OJ, Jones KM, Chappell AM, Werner DF, Homanics GE, Weiner JL. Paradoxical increases in behavioral and synaptic sensitivity to ethanol in knockin mice with ethanol-insensitive alpha1 GABA receptors [abstract]. Alcohol Clin Exp Res. 2007;31(6 Suppl):10A.

Jones KM, Chappell AM, Weiner JL. A comparison of umami (MSG) vs. sweet (sucrose) fading in the initiation of operant ethanol self-administration [abstract]. Alcohol Clin Exp Res. 2007;31(6 Suppl):91A.

Molina DP, Ariwodola OJ, Weiner JL, Brunso-Bechtold JK, Adams MM. AMPA- and NMDA-dependent synaptic transmission is enhanced by growth hormone (GH) and insulin-like growth factor 1 (IGF-1) similarly in young and old Fisher 344 x Brown Norway (F344xBN) [abstract]. Soc Neurosci Abstr. 2007;2007(Abstr Viewer):.

Weiner JL, Valenzuela CF. Ethanol modulation of GABAergic transmission: the view from the slice. Pharmacol Ther. 2006;111(3):533-554.

DuBois DW, Perlegas A, Floyd DW, Weiner JL, McCool BA. Distinct functional characteristics of the lateral/basolateral amygdala GABAergic system in C57BL/6J and DBA/2J mice. J Pharmacol Exp Ther. 2006;318(2):629-640.

Crowder TL, Ariwodola OJ, Weiner JL. Kainate receptor activation potentiates GABAergic synaptic transmission in the nucleus accumbens core. Brain Res. 2006;1088(1):73-82.

Werner DF, Blednov YA, Ariwodola OJ, Silberman Y, Logan E, Berry RB, Borghese CM, Matthews DB, Weiner JL, Harrison NL, et al. Knockin mice with ethanol-insensitive alpha 1-containing gamma-aminobutyric acid type A receptors display selective alterations in behavioral responses to ethanol. J Pharmacol Exp Ther. 2006;319(1):219-227.

Ariwodola OJ, Silberman Y, Chappell AM, Weiner JL. Identification of possible synaptic correlates of an ethanol drinking-related behavior [abstract]. Alcohol Clin Exp Res. 2006;30(6 Suppl):135A.

Chappell AM, Weiner JL. Relationship between initial sensitivity to the acute locomotor effects of ethanol and ethanol self-administration [abstract]. Alcohol Clin Exp Res. 2006;30(6 Suppl):188A.

Silberman Y, Weiner JL. Ethanol potentiation of GABAergic neurotransmission in the basolaterla [sic] amygdala: a role for norepinephrine? [abstract]. Alcohol Clin Exp Res. 2006;30(6 Suppl):18A.

John CE, Budygin EA, Weiner JL, Jones SR. NMDA receptor deficient mice display altered synaptic function and reward related behaviors [abstract]. Neuropsychopharmacology. 2006;31(Suppl):S76.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

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