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Christopher T. Whitlow, M.D., Ph.D.Wake Forest School of Medicine

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Christopher T. Whitlow, M.D., Ph.D.

Associate Professor,
Substance Addiction& Abuse Ctr



Clinical Interests

Advanced Neuroradiology MRI Techniques, Neuroradiology, Radiology

Contact Information

Department: 336-716-7849

Email: cwhitlow@wakehealth.edu

Insurance Accepted »

Education & Training

  • B.A., East Carolina University, 1997
  • M.D., WFU School of Medicine, 2004
  • Ph.D., WFU School of Medicine, 2004
  • Internship, Medicine, Moses H Cone Mem Hosp, 2005
  • Residency, Diagnostic Radiology, NC Baptist Hospital, 2009
  • Fellowship, Diagnostic Radiology, Wake Forest Baptist Med Ctr, 2010

Board Certifications

  • American Board of Radiology, Diagnostic Radiology

NPI Number

  • 1063696557
Christopher T. Whitlow, M.D., Ph.D.

Doctor Rating

No Rating Available
Why No Ratings?

Christopher T. Whitlow, M.D., Ph.D.

Associate Professor, Radiology
Substance Addiction& Abuse Ctr
Comprehensive Cancer Center
Biomedical Engineering
Biostatistical Sciences

Research Interests

Brain Mapping; Brain; Magnetic Resonance Imaging; Brain Diseases; Image Processing, Computer-Assisted
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Contact Information

Academic: 336-716-7849 | Department: 336-716-7849

Email: cwhitlow@wakehealth.edu

Recent Publications

Susceptibility-weighted imaging and magnetic Resonance spectroscopy in concussion. Kirov II, Whitlow CT, Zamora C.. Neuroimaging Clin N Am. 2018;28(1):91-105.

Functional MR imaging: blood oxygen level-dependent and resting state techniques in mild traumatic brain injury. Rosenthal S, Gray M, Fatima H, Sair HI, Whitlow CT.. Neuroimaging Clin N Am. 2018;28(1):107-115.

Cerebral structure and cognitive performance in African Americans and European Americans with type 2 diabetes. Hsu FC, Sink KM, Hugenschmidt CE, Williamson JD, Hughes TM, Palmer ND, Xu J, Smith SC, Wagner BC, Whitlow CT, Bowden DW, Maldjian JA, Divers J, Freedman BI.. J Gerontol A Biol Sci Med Sci. 2018;73(3):407-414.

The Apathy in Dementia Methylphenidate Trial 2 (ADMET 2): study protocol for a randomized controlled trial. Scherer RW, Drye L, Mintzer J, Lanctot K, Rosenberg P, Herrmann N, Padala P, Brawman-Mintzer O, Burke W, Craft S, Lerner AJ, Levey A, Porsteinsson A, van Dyck CH, Baker LD, Williamson JD, Bell RA, Espeland M, Miller ME, Mott RT, Rapp S, Hayden K,.. Trials. 2018;19(1):46.

vmPFC activation during a stressor predicts positive emotions during stress recovery. Yang X, Garcia K, Jung Y, Whitlow CT, McRae K, Waugh CE.. Soc Cogn Affect Neurosci. 2018;13(3):256-263.

Radiosynthesis and in vivo evaluation of [11C]MPC-6827, the first brain penetrant microtubule PET ligand. Kumar JSD, Sai KKS, Prabhakaran J, Oufkir HR, Ramanathan G, Whitlow CT, Dileep H, Mintz A, Mann JJ.. J Med Chem. 2018;61(5):2118-2123.

Developing a hippocampal neural prosthetic to facilitate human memory encoding and recall. Hampson RE, Song D, Robinson BS, Fetterhoff D, Dakos AS, Roeder BM, She X, Wicks RT, Witcher MR, Couture DE, Laxton AW, Munger-Clary H, Popli G, Sollman MJ, Whitlow CT, Marmarelis VZ, Berger TW, Deadwyler SA.. J Neural Eng. 2018;15(3):036014.

Labyrinthitis ossificans in a cynomolgus macaque (Macaca fascicularis). Balamayooran G, Atkins HM, Whitlow CT, Aycock ST, Nader MA, Cline JM, Caudell DL.. Comp Med. 2018;():.

Head impact exposure in youth football: comparing age- and weight-based levels of play. Kelley ME, Urban JE, Miller LE, Jones DA, Espeland MA, Davenport EM, Whitlow CT, Maldjian JA, Stitzel JD.. J Neurotrauma. 2017;34(11):1939-1947.

Effects of regular and long-acting insulin on cognition and Alzheimer's disease biomarkers: a pilot clinical trial. Craft S, Claxton A, Baker LD, Hanson AJ, Cholerton B, Trittschuh EH, Dahl D, Caulder E, Neth B, Montine TJ, Jung Y, Maldjian J, Whitlow C, Friedman S.. J Alzheimers Dis. 2017;57(4):1325-1334.

Associations of early kidney disease with brain magnetic resonance imaging and cognitive function in African Americans with type 2 diabetes mellitus. Freedman BI, Sink KM, Hugenschmidt CE, Hughes TM, Williamson JD, Whitlow CT, Palmer ND, Miller ME, Lovato LC, Xu J, Smith SC, Launer LJ, Barzilay JI, Cohen RM, Sullivan MD, Bryan RN, Wagner BC, Bowden DW, Maldjian JA, Divers J.. Am J Kidney Dis. 2017;70(5):627-637.

Investigating the effects of repetitive head impact exposure in youth football using neurite orientation dispersion and density imaging (NODDI) [abstract]. Whitlow C, Bahrami N, Urban J, Davenport E, Jung Y, Espeland M, Powers A, Stitzel J, Maldjian J.. Brain Inj. 2017;31(6-7):984.

Neural predictors of emotional inertia in daily life. Waugh CE, Shing EZ, Avery BM, Jung Y, Whitlow CT, Maldjian JA.. Soc Cogn Affect Neurosci. 2017;12(9):1448-1459.

Machine learning applications to resting-state functional MR imaging analysis. Billings JM, Eder M, Flood WC, Dhami DS, Natarajan S, Whitlow CT.. Neuroimaging Clin N Am. 2017;27(4):609-620.

Feasibility of proton MRS for assessing cerebral metabolic activity of an Atkins-based diet in patients with glioma [abstract]. Schreck KC, Berrington A, Barron BM, Blair L, Hartman A, Kossoff E, Easter L, Whitlow C, Hsu FC, Cervenka MC, Blakeley JO, Barker PB, Strowd RE.. Neuro Oncol. 2017;19(Suppl 6):163.

Multi-atlas library for eliminating normalization failures in non-human primates. Maldjian JA, Shively CA, Nader MA, Friedman DP, Whitlow CT.. Neuroinformatics. 2016;14(2):183-190.

ATP1A3 mutation in adult rapid-onset ataxia. Sweadner KJ, Toro C, Whitlow CT, Snively BM, Cook JF, Ozelius LJ, Markello TC, Brashear A.. PLoS One. 2016;11(3):e0151429.

Multi-infarct dementia. Mintz A, Neth BJ, Whitlow CT. In: Bennett P, Oza UD, eds. Diagnostic imaging: nuclear medicine. 2nd ed. Philadelphia (PA): Elsevier;2016: 2: 52-53.

Abnormalities in diffusional kurtosis metrics related to head impact exposure in a season of high school varsity football. Davenport EM, Apkarian K, Whitlow CT, Urban JE, Jensen JH, Szuch E, Espeland MA, Jung Y, Rosenbaum DA, Gioia G, Powers AK, Stitzel JD, Maldjian JA.. J Neurotrauma. 2016;33(23):2133-2146.

Effects of cumulative subconcussive head impact exposure associated with youth football on white matter microstructural integrity [abstract]. Whitlow C, Bahrami N, Rosenthal S, Davenport E, Urban J, Vaughan C, Gioia G Stitzel J, Maldjian J.. Brain Inj. 2016;30(5-6):813.

Subconcussive impact exposure and computational modelling of the brain using an atlas-based biomechanical finite element model [abstract]. Stitzel JD, Urban JE, Miller LE, Kelley ME, Jones DA, Davenport EM, Whitlow CT, Maldjian JA, Powers AK.. Brain Inj. 2016;30(5-6):809-810.

APOL1 renal-risk variants associate with reduced cerebral white matter lesion volume and increased gray matter volume. Freedman BI, Gadegbeku CA, Bryan RN, Palmer ND, Hicks PJ, Ma L, Rocco MV, Smith SC, Xu J, Whitlow CT, Wagner BC, Langefeld CD, Hawfield AT, Bates JT, Lerner AJ, Raj DS, Sadaghiani MS, Toto RD, Wright JT Jr, Bowden DW, Williamson JD, Sink KM,.. Kidney Int. 2016;90(2):440-449.

APOE genotypes associate with cognitive performance but not cerebral structure: Diabetes Heart Study MIND. Palmer Allred ND, Raffield LM, Hardy JC, Hsu FC, Divers J, Xu J, Smith SC, Hugenschmidt CE, Wagner BC, Whitlow CT, Sink KM, Maldjian JA, Williamson JD, Bowden DW, Freedman BI.. Diabetes Care. 2016;39(12):2225-2231.

Subconcussive head impact exposure and white matter tract changes over a single season of youth football. Bahrami N, Sharma D, Rosenthal S, Davenport EM, Urban JE, Wagner B, Jung Y, Vaughan CG, Gioia GA, Stitzel JD, Whitlow CT, Maldjian JA.. Radiology. 2016;281(3):919-926.

Evaluation of morphological changes in the adult skull with age and sex. Urban JE, Weaver AA, Lillie EM, Maldjian JA, Whitlow CT, Stitzel JD.. J Anat. 2016;229(6):838-846.

WE-FG-206-05: new arterial spin labeling method for simultaneous estimation of arterial cerebral blood volume, cerebral blood flow and arterial transit time [abstract]. Johnston M, Liu H, Whitlow C, Jung Y.. Med Phys. 2016;43(6):3831.

SU-G-IeP1-12: size selective arterial cerebral blood volume mapping using multiple inversion time arterial spin labeling [abstract]. Jung Y, Johnston M, Liu H, Whitlow C.. Med Phys. 2016;43(6):3647.

Associations between brain structure and executive function in patients with rapid-onset dystonia-parkinsonism [abstract]. Whitlow CT, Cook JF, Snively BM, Sweadner KJ, Haq IU, Stacy M, Ozelius LJ, Brashear A.. Ann Neurol. 2016;80(Suppl 20):S139-S140.

Cerebral structural changes in diabetic kidney disease: African American-Diabetes Heart Study MIND. Sink KM, Divers J, Whitlow CT, Palmer ND, Smith SC, Xu J, Hugenschmidt CE, Wagner BC, Williamson JD, Bowden DW, Maldjian JA, Freedman BI.. Diabetes Care. 2015;38(2):206-212.

Imaging evidence and recommendations for traumatic brain injury: conventional neuroimaging techniques. Wintermark M, Sanelli PC, Anzai Y, Tsiouris AJ, Whitlow CT.. J Am Coll Radiol. 2015;12(2):e1-e14.

Imaging evidence and recommendations for traumatic brain injury: advanced neuro- and neurovascular imaging techniques. Wintermark M, Sanelli PC, Anzai Y, Tsiouris AJ, Whitlow CT.. AJNR Am J Neuroradiol. 2015;36(2):E1-E11.

Traumatic brain injury imaging research roadmap. Wintermark M, Coombs L, Druzgal TJ, Field AS, Filippi CG, Hicks R, Horton R, Lui YW, Law M, Mukherjee P, Norbash A, Riedy G, Sanelli PC, Stone JR, Sze G, Tilkin M, Whitlow CT, Wilde EA, York G, Provenzale JM.. AJNR Am J Neuroradiol. 2015;36(3):E12-E23.

Structural and functional assessment of the brain in European Americans with mild-to-moderate kidney disease: Diabetes Heart Study-MIND. Murea M, Hsu FC, Cox AJ, Hugenschmidt CE, Xu J, Adams JN, Raffield LM, Whitlow CT, Maldjian JA, Bowden DW, Freedman BI.. Nephrol Dial Transplant. 2015;30(8):1322-1329.

A child with fever and swelling of the forehead. Liu A, Powers AK, Whigham AS, Whitlow CT, Shetty AK.. Clin Pediatr (Phila). 2015;54(8):803-805.

Combining clinical neuroimaging and real-world mechanical impact data to investigate motor vehicle crash-related subarachnoid hemorrhage [abstract]. Urban J, Lynch S, Lowther E, Whitlow C, Dunn A, Stitzel JD.. J Head Trauma Rehabil. 2015;30(3):E108-E109.

Effects of type 2 diabetes on brain structure and cognitive function: African American-Diabetes Heart Study MIND. Whitlow CT, Sink KM, Divers J, Smith SC, Xu J, Palmer ND, Hugenschmidt CE, Williamson JD, Bowden DW, Freedman BI, Maldjian JA.. AJNR Am J Neuroradiol. 2015;36(9):1648-1653.

Subclinical atherosclerosis is inversely associated with gray matter volume in African Americans with type 2 diabetes. Freedman BI, Divers J, Whitlow CT, Bowden DW, Palmer ND, Smith SC, Xu J, Register TC, Carr JJ, Wagner BC, Williamson JD, Sink KM, Maldjian JA.. Diabetes Care. 2015;38(11):2158-2165.

A comprehensive assessment of radiographic, clinical, and treatment related risk factors for metastasis related intracranial hemorrhage in metastatic melanoma following radiation therapy [abstract]. Lucas JT Jr, Lack C, Wagner B, Kuremsky JG, Mu F, Chan MD, Sweeney A, Maldjian J, Whitlow C.. Int J Radiat Oncol Biol Phys. 2015;93(3 Suppl):E111.

Computed tomography demonstrates abnormalities of contralateral ear in subjects with unilateral sensorineural hearing loss. Marcus S, Whitlow CT, Koonce J, Zapadka ME, Chen MY, Williams DW III, Lewis M, Evans AK.. Int J Pediatr Otorhinolaryngol. 2014;78(2):268-271.

Abnormal white matter integrity related to head impact exposure in a season of high school varsity football. Davenport EM, Whitlow CT, Urban JE, Espeland MA, Jung Y, Rosenbaum DA, Gioia G, Powers AK, Stitzel JD, Maldjian JA.. J Neurotrauma. 2014;31(19):1617-1624.

Vervet MRI atlas and label map for fully automated morphometric analyses. Maldjian JA, Daunais JB, Friedman DP, Whitlow CT.. Neuroinformatics. 2014;12(4):543-550.

Development of a risk weighted cumulative exposure metric for the analysis of head impact data [abstract]. Stitzel J, Urban J, Davenport E, Maldjian J, Whitlow C, Powers A.. Brain Inj. 2014;28(5-6):802.

Graph theoretical analysis of resting-state MEG data: identifying interhemispheric connectivity and the default mode. Maldjian JA, Davenport EM, Whitlow CT.. Neuroimage. 2014;96():88-94.

Rapid-onset dystonia-parkinsonism associated with the I758S mutation of the ATP1A3 gene: a neuropathologic and neuroanatomical study of four siblings. Oblak AL, Hagen MC, Sweadner KJ, Haq I, Whitlow CT, Maldjian JA, Epperson F, Cook JF, Stacy M, Murrell JR, Ozelius LJ, Brashear A, Ghetti B.. Acta Neuropathol. 2014;128(1):81-98.

Safety assessment, artifact reduction, and description of geometric distortion associated with diffusion imaging (DWI) with rigid head frame immobilization for stereotactic radiosurgery [abstract]. Lucas JT, DiNotto J, Dolesh W, Jung Y, Whitlow CT, Maldjian JA, Chan MD, Bourland J.. Int J Radiat Oncol Biol Phys. 2014;90(1 Suppl):S903.

Kidney disease and cognitive function: African American-Diabetes Heart Study MIND. Palmer ND, Sink KM, Smith SC, Xu J, Bowden DW, Hugenschmidt CE, Whitlow CT, Williamson JD, Maldjian JA, Divers J, Freedman BI.. Am J Nephrol. 2014;40(3):200-207.

Cellular microparticles as blood-borne endothelial biomarkers in patients with malignant gliomas [abstract]. Lesser G, Harmon M, Khan I, Whitlow C, Brown W.. Neuro Oncol. 2014;16(Suppl 5):v27.

Rapid-onset dystonia-Parkinsonism presenting as tremor-dominant Parkinson's disease (PO4.161) [abstract]. Tate J, Brashear A, Whitlow C, Snively B, Ozelius L, Sweadner K, Stacy M, Haq I.. Neurology. 2013;80(1 Meeting Abstracts):P04.

Evaluation of the extent and distribution of diffuse axonal injury from real world motor vehicle crashes--biomed 2013. Lillie EM, Urban JE, Lynch SK, Whitlow CT, Stitzel JD.. Biomed Sci Instrum. 2013;49():297-304.

An unusual aetiology for internuclear ophthalmoplegia. Vishwas MS, Whitlow CT, Ihtsham ul Haq.. BMJ Case Rep. 2013;2013():.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Associate Professor, Radiology

Clinical Interests

Advanced Neuroradiology MRI Techniques, Neuroradiology, Radiology
Christopher T. Whitlow, M.D., Ph.D.

Christopher T. Whitlow, M.D., Ph.D.

Associate Professor, Radiology
Substance Addiction& Abuse Ctr
Comprehensive Cancer Center
Biomedical Engineering
Biostatistical Sciences

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