Raghunatha Yammani, Ph.D., Assistant Professor Internal Medicine-Molecular Medicine

Raghunatha Yammani, Ph.D.

Assistant Professor, Molecular Medicine
Translational Science Institute
Sticht Center on Aging
Arthritis-Musculoskeletal DRC
WFU Primate Center
Translational Science Institute

Contact Information

Academic: 336-716-1578 | Department: 336-716-2011

Education & Training

Ph.D., Osmania University-India , 1999
B.S., Osmania University-India , 1990
M.S., Free Standing Institute-India , 1993
Fellowship, Indian Institute Of Science-In, 1999
Fellowship, Medical College of Wisconsin, 2004
Fellowship, Rush Medical College, 2004

Raghunatha Yammani, Ph.D.

Assistant Professor, Molecular Medicine
Translational Science Institute
Sticht Center on Aging
Arthritis-Musculoskeletal DRC
WFU Primate Center
Translational Science Institute

Research Interests

arthritis, degenerative disorders, metabolism, model development, obesity, statistics/mathematics

Contact Information

Academic: 336-716-1578 | Department: 336-716-2011

Recent Publications

Yammani RR, Loeser RF. Extracellular nicotinamide phosphoribosyltransferase (NAMPT/visfatin) inhibits insulin-like growth factor-1 signaling and proteoglycan synthesis in human articular chondrocytes. Arthritis Res Ther. 2012;14(1):R23.

Yammani RR. S100 proteins in cartilage: role in arthritis. Biochim Biophys Acta. 2012;1822(4):600-606.

Miranda KJ, Loeser RF, Yammani RR. Sumoylation and nuclear translocation of S100A4 regulate IL-1beta-mediated production of matrix metalloproteinase-13. J Biol Chem. 2010;285(41):31517-24.

Miranda KJ, Loeser RF, Yammani RR. Response to Berge et al.: comment on the importance of S100A4 in regulation of MMP-13 [letter]. J Biol Chem. 2010;285(53):Ie24.

Cravero JD, Carlson CS, Im H-J, Yammani RR, Long D, Loeser RF. Increased expression of the Akt/PKB inhibitor TRB3 in osteoarthritic chondrocytes inhibits insulin-like growth factor 1-mediated cell survival and proteoglycan synthesis. Arthritis Rheum. 2009;60(2):492-500.

Yammani RR, Long D, Loeser RF. Interleukin-7 stimulates secretion of S100A4 by activating the JAK/STAT signaling pathway in human articular chondrocytes. Arthritis Rheum. 2009;60(3):792-800.

Ahuja R, Yammani R, Bauer JA, Kaira S, Seetharam S, Seetharam B. Interactions of cubillin with megalin and the product of the amnionless gene (AMN): effect on its stability. Biochem J. 2008;410(2):301-308.

Bose S, Kalra S, Yammani RR, Ahuja R, Seetharam B. Plasma membrane delivery, endocytosis and turnover of transcobalamin receptor in polarized human intestinal epithelial cells. J Physiol. 2007;581(Pt 2):457-466.

Yammani RR, Carlson CS, Bresnick AR, Loeser RF. Increase in production of matrix metalloproteinase 13 by human articular chondrocytes due to stimulation with S100A4: role of the receptor for advanced glycation end products. Arthritis Rheum. 2006;54(9):2901-2911.

Loeser RF, Yammani R, Erickson E, King B, Poole L. Chondrocyte MMP-13 expression in response to alpha 5 beta 1 integrin stimulation requires protein sulfenic acids as signaling intermediates [abstract]. Arthritis Rheum. 2006;54(9 Suppl):S318.

All Publications

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Assistant Professor, Molecular Medicine

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Raghunatha Yammani, Ph.D.

Contact Information

Education & Training

Raghunatha Yammani, Ph.D.

Research Interests

Contact Information

Recent Publications

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