Profile

James J. Yoo, M.D., Ph.D.Wake Forest School of Medicine

James J. Yoo, M.D., Ph.D.

Professor,



Contact Information

Academic: 336-713-7294 | Department: 336-716-2011

Email: jyoo@wakehealth.edu

Education & Training

  • B.A., University of Illinois-Urbana/Champaign, 1984
  • M.D., Korea University Medical College-Korea, 1989
  • M.S., Korea University Medical College-Korea, 1992
  • Ph.D., Korea University Medical College-Korea, 1994
  • Fellowship, Harvard Medical School, 1996
James J. Yoo, M.D., Ph.D.

James J. Yoo, M.D., Ph.D.

Professor, Institute for Regenerative Medicine
Office of Women in Medicine and Science
Physiology & Pharmacology
Translational Science Institute

Research Interests

biotechnology, cardiac function, cell growth, differentiation,d, critical/intensive care medici, engineering/bioengineering, medical technology/devices, surgery/trauma/burns/trauma, transplantation, vascular diseases

Contact Information

Academic: 336-713-7294 | Department: 336-716-2011

Email: jyoo@wakehealth.edu

Recent Publications

De Filippo RE, Kornitzer BS, Yoo JJ, Atala A. Penile urethra replacement with autologous cell-seeded tubularized collagen matrices. J Tissue Eng Regen Med. 2015;9(3):257-264.

Chun SY, Mack DL, Moorefield E, Oh SH, Kwon TG, Pettenati MJ, Yoo JJ, Coppi PD, Atala A, Soker S. Pdx1 and controlled culture conditions induced differentiation of human amniotic fluid-derived stem cells to insulin-producing clusters. J Tissue Eng Regen Med. 2015;9(5):540-549.

Ko IK, Peng L, Peloso A, Smith CJ, Dhal A, Deegan DB, Zimmerman C, Clouse C, Zhao W, Shupe TD, Soker S, Yoo JJ, Atala A. Bioengineered transplantable porcine livers with re-endothelialized vasculature. Biomaterials. 2015;40():72-79.

Hunsberger J, Harrysson O, Shirwaiker R, Starly B, Wysk R, Cohen P, Allickson J, Yoo J, Atala A. Manufacturing road map for tissue engineering and regenerative medicine technologies. Stem Cells Transl Med. 2015;4(2):130-135.

Ahn H, Ju YM, Takahashi H, Williams DF, Yoo JJ, Lee SJ, Okano T, Atala A. Engineered small diameter vascular grafts by combining cell sheet engineering and electrospinning technology. Acta Biomater. 2015;16():14-22.

Williams JK, Eckman D, Dean A, Moradi M, Allickson J, Cline JM, Yoo JJ, Atala A. The dose-effect safety profile of skeletal muscle precursor cell therapy in a dog model of intrinsic urinary sphincter deficiency. Stem Cells Transl Med. 2015;4(3):286-294.

Choi JY, Chun SY, Kim BS, Kim HT, Yoo ES, Shon YH, Lim JO, Yun SJ, Song PH, Chung SK, Yoo JJ, Kwon TG. Pre-clinical efficacy and safety evaluation of human amniotic fluid-derived stem cell injection in a mouse model of urinary incontinence. Yonsei Med J. 2015;56(3):648-657.

Chun SY, Oh SH, Yoo JJ, Kwon TG. Fabrication and characterization techniques for decellularized organ scaffolds. Tissue Eng Regen Med. 2015;12(Suppl 1):1-10.

Kim IH, Ko IK, Atala A, Yoo JJ. Whole kidney engineering for clinical translation. Curr Opin Organ Transplant. 2015;20(2):165-170.

Tatara AM, Kretlow JD, Spicer PP, Lu S, Lam J, Liu W, Cao Y, Liu G, Jackson JD, Yoo JJ, Atala A, van den Beucken JJ, Jansen JA, Kasper FK, Ho T, Demian N, Miller MJ, Wong ME, Mikos AG. Autologously generated tissue-engineered bone flaps for reconstruction of large mandibular defects in an ovine model. Tissue Eng Part A. 2015;21(9-10):1520-1528.

Atala AJ, Yoo JJ, Grace L, Lim G, Lee SJ, inventors; Wake Forest University Health Sciences, assignee. Production of tissue engineered digits and limbs. United States patent US 9,039,782. 2015 May 26. 2015;():.

Atala AJ, Hodges SJ, Sullivan CA, Yoo JJ, inventors; Wake Forest University Health Sciences, assignee. Medical devices incorporating collagen inhibitors. Germany patent DE 2101834. 2015 Mar 25 (patent also held in European Patent Office, France, and Greece). 2015;():.

Xu T, Yoo JJ, Atala AJ, inventors; Wake Forest University Health Sciences, assignee. Inkjet gene printing. United States patent US 9,045,757. 2015 June 2. 2015;():.

Xu T, Yoo JJ, Atala AJ, Dice D, inventors; Wake Forest University Health Sciences, assignee. Inkjet printing of tissues and cells. United States patent US 9,005,972. 2015 Apr 4. 2015;():.

Chandra PK, Ross CL, Smith LC, Jeong SS, Kim J, Yoo JJ, Harrison BS. Peroxide-based oxygen generating topical wound dressing for enhancing healing of dermal wounds. Wound Repair Regen. 2015;():.

Chung HC, Ko IK, Atala A, Yoo JJ. Cell-based therapy for kidney disease. Korean J Urol. 2015;56(6):412-421.

Merceron TK, Burt M, Seol YJ, Kang HW, Lee SJ, Yoo JJ, Atala A. A 3D bioprinted complex structure for engineering the muscle-tendon unit. Biofabrication. 2015;7(3):035003.

Park JH, Hong JM, Ju YM, Jung JW, Kang HW, Lee SJ, Yoo JJ, Kim SW, Kim SH, Cho DW. A novel tissue-engineered trachea with a mechanical behavior similar to native trachea. Biomaterials. 2015;62():106-115.

Moon KH, Ko IK, Yoo JJ, Atala A. Kidney diseases and tissue engineering. Methods. 2015;():.

Joo S, Lim HJ, Jackson JD, Atala A, Yoo JJ. Myogenic-induced mesenchymal stem cells are capable of modulating the immune response by regulatory T cells. J Tissue Eng. 2014;5():.

Campeau L, Soler R, Sittadjody S, Pareta R, Nomiya M, Zarifpour M, Opara EC, Yoo JJ, Andersson KE. Effects of allogeneic bone marrow derived mesenchymal stromal cell therapy on voiding function in a rat model of Parkinson disease. J Urol. 2014;191(3):850-859.

Cho HJ, Lee SH, Yoo JJ, Shon YH. Evaluation of cell viability and apoptosis in human amniotic fluid-derived stem cells with natural cryoprotectants. Cryobiology. 2014;68(2):244-250.

Orabi H, Aboushwareb T, Tan J, Yoo JJ, Atala A. Can computed tomography--assisted virtual endoscopy be an innovative tool for detecting urethral tissue pathologies. Urology. 2014;83(4):930-938.

Hwang CM, Lee BK, Green D, Jeong SY, Khang G, Jackson JD, Atala A, Lee SJ, Yoo JJ. Auricular reconstruction using tissue-engineered alloplastic implants for improved clinical outcomes. Plast Reconstr Surg. 2014;133(3):360e-369e.

Lee SJ, Yoo JJ, Atala A. Recent applications of polymeric biomaterials and stem cells in tissue engineering and regenerative medicine. Polymer [Korea]. 2014;38(2):113-128.

Raya-Rivera AM, Esquiliano D, Fierro-Pastrana R, Lopez-Bayghen E, Valencia P, Ordorica-Flores R, Soker S, Yoo JJ, Atala A. Tissue-engineered autologous vaginal organs in patients: a pilot cohort study. Lancet. 2014;384(9940):329-336.

Kang H-W, Kengla C, Lee SJ, Yoo JJ, Atala A. 3-D organ printing technologies for tissue engineering applications In: Narayan R, ed. Rapid prototyping of biomaterials: principles and applications. Oxford: Woodhead publishing;2014: 236-253.

Kim J, Andersson KE, Jackson JD, Lee SJ, Atala A, Yoo JJ. Downregulation of metabolic activity increases cell survival under hypoxic conditions: potential applications for tissue engineering. Tissue Eng Part A. 2014;20(15-16):2265-2272.

Atala AJ, Yoo JJ, Lim HJ, Czerw, Soker S, inventors; Wake Forest University Health Sciences, assignee. Production of tissue engineered digits and limbs. United States patent US 8728463. 2014 May 20. 2014;():.

Atala AJ, Hodges SJ, Sullivan CA, Yoo JJ, inventors; Wake Forest University Health Sciences, assignee. Medical devices incorporating collagen inhibitors. United States patent US 8668703. 2014 Mar 11 (patent also held in China). 2014;():.

Atala AJ, Xu T, Yoo JJ, inventors; Wake Forest University Health Sciences, assignee. Inkjet gene printing. Australia patent AU 2008262331. 2014 Jan 30. 2014;():.

Atala AJ, Yoo JJ, inventors; Wake Forest University Health Sciences, assignee. Selective cell therapy for the treatment of renal failure. Australia patent AU 2008262333. 2014 June 20 (patent also held in China). 2014;():.

Atala AJ, Dice D, Xu T, Yoo JJ, inventors; Wake Forest University Health Sciences, assignee. Inkjet printing of tissues and cells. United States patent US 8691274. 2014 Apr 8. 2014;():.

Ju YM, Atala A, Yoo JJ, Lee SJ. In situ regeneration of skeletal muscle tissue through host cell recruitment. Acta Biomater. 2014;10(10):4332-4339.

Cheng X, Yoo JJ, Hale RG. Biomask for skin regeneration [editorial]. Regen Med. 2014;9(3):245-248.

Melgarejo Y, Garcia J, Gutierrez C, Lee SJ, Yoo J, Atala A, Ibarra C, Velasquillo C. Development of elastic cartilage using a 3D bioprinted ear shape structure, potential for ear reconstruction [abstract]. J Tissue Eng Regen Med. 2014;8(Suppl 1):462-463.

Seol YJ, Kang HW, Lee SJ, Atala A, Yoo JJ. Bioprinting technology and its applications. Eur J Cardiothorac Surg. 2014;46(3):342-348.

Jackson JR, Kim N, Kim J, Andersson KE, Yoo J, Atala A. Induction and maintenance of cellular hypometabolsm for improved tissue survival for reconstructive procedures [abstract]. J Am Coll Surg. 2014;219(3 Suppl):S142.

Jackson JR, Kim N, Yoo J, Lee SJ, Atala A. Combination of small RNAs enhances muscle development [abstract]. J Am Coll Surg. 2014;219(3 Suppl):S138.

Jackson JR, Ko IK, Lee SJ, Atala A, Yoo J. Formation of neuromuscular junction for accelerated recovery of muscle function [abstract]. J Am Coll Surg. 2014;219(3 Suppl):S139-S140.

Zambon JP, Magalhaes RS, Ko I, Ross CL, Orlando G, Peloso A, Atala A, Yoo JJ. Kidney regeneration: where we are and future perspectives. World J Nephrol. 2014;3(3):24-30.

Jackson JR, Ko IK, Abolbashari M, Huling J, Zambon J, Kim C, Orlando G, Yoo J, Aboushwareb T, Atala A. CD31 antibody conjugation improves re-endothelialization of acellular kidney scaffolds for whole organ engineering [abstract]. J Am Coll Surg. 2014;219(3 Suppl):S141.

Chun SY, Kwon JB, Chae SY, Lee JK, Bae JS, Kim BS, Kim HT, Yoo ES, Lim JO, Yoo JJ, Kim WJ, Kim BW, Kwon TG. Combined injection of three different lineages of early-differentiating human amniotic fluid-derived cells restores urethral sphincter function in urinary incontinence. BJU Int. 2014;114(5):770-783.

Jeong C, Chung HY, Lim HJ, Lee JW, Choi KY, Yang JD, Cho BC, Lim JO, Yoo JJ, Lee SJ, Atala AJ. Applicability and safety of in vitro skin expansion using a skin bioreactor: a clinical trial. Arch Plast Surg. 2014;41(6):661-667.

Ahn H, Ju Y, Takahashi H, Okano T, Yoo JJ, Atala A, Lee S. Tissue-engineered vascular grafts by combining cell sheet and electrospun scaffold [abstract]. Tissue Eng Part A. 2014;20(Suppl 1):S94.

Burt MA, Merceron T, Lee SJ, Jackson JD, Yoo JJ, Atala A. Bioprinting technology for repair of a musculotendinous defect in the gastrocnemius-achilles junction of nude rats [abstract]. Tissue Eng Part A. 2014;20(Suppl 1):S134.

Hassan S, Burns J, Oliver E, Kiell E, Yoo J, Jackson J, Atala A. In vivo delivery of MYC gene to regenerate hair cells for restoring hearing and balance [abstract]. Tissue Eng Part A. 2014;20(Suppl 1):S22.

Ju Y, Ahn H, Kim C, Lee J, Yoo JJ, Atala A, Lee S. A cellularized electrospun vascular scaffold for blood vessel regeneration [abstract]. Tissue Eng Part A. 2014;20(Suppl 1):S36.

Ju Y, Shapiro L, Ko I, Yoo JJ, Atala A, Lee S. Host stem cell recruitment for in situ muscle tissue regeneration [abstract]. Tissue Eng Part A. 2014;20(Suppl 1):S97.

Kengla C, Seol Y, Kim H, Kang H, Lee S, Yoo JJ, Atala A. Biofabrication of tissue constructs for craniomaxillofacial reconstruction [abstract]. Tissue Eng Part A. 2014;20(Suppl 1):S33.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

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