Profile

James J. Yoo, M.D., Ph.D.Wake Forest School of Medicine

James J. Yoo, M.D., Ph.D.

Professor,



Contact Information

Academic: 336-713-7294 | Department: 336-716-2011

Email: jyoo@wakehealth.edu

Education & Training

  • B.A., University of Illinois-Urbana/Champaign, 1984
  • M.D., Korea University Medical College-Korea, 1989
  • M.S., Korea University Medical College-Korea, 1992
  • Ph.D., Korea University Medical College-Korea, 1994
  • Fellowship, Harvard Medical School, 1996
James J. Yoo, M.D., Ph.D.

James J. Yoo, M.D., Ph.D.

Professor, Institute for Regenerative Medicine
Office of Women in Medicine and Science
Physiology & Pharmacology
Translational Science Institute

Research Interests

Tissue Engineering; Tissue Scaffolds; Stem Cells; Amniotic Fluid; Animals
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Contact Information

Academic: 336-713-7294 | Department: 336-716-2011

Email: jyoo@wakehealth.edu

Recent Publications

Kidney diseases and tissue engineering. Moon KH, Ko IK, Yoo JJ, Atala A.. Methods. 2016;99():112-119.

Repopulation of porcine kidney scaffold using porcine primary renal cells. Abolbashari M, Agcaoili SM, Lee MK, Ko IK, Aboushwareb T, Jackson JD, Yoo JJ, Atala A.. Acta Biomater. 2016;29():52-61.

Combination of small RNAs for skeletal muscle regeneration. Kim N, Yoo JJ, Atala A, Lee SJ.. FASEB J. 2016;30(3):1198-1206.

Fabrication of biomimetic vascular scaffolds for 3D tissue constructs using vascular corrosion casts. Huling J, Ko IK, Atala A, Yoo JJ.. Acta Biomater. 2016;32():190-197.

A 3D bioprinting system to produce human-scale tissue constructs with structural integrity. Kang HW, Lee SJ, Ko IK, Kengla C, Yoo JJ, Atala A.. Nat Biotechnol. 2016;34(3):312-319.

Surgical therapies and tissue engineering: at the intersection between innovation and regulation [editorial]. Rubin JP, Gurtner GC, Liu W, March KL, Seppanen-Kaijansinkko R, Yaszemski MJ, Yoo JJ.. Tissue Eng Part A. 2016;22(5-6):397-400.

Biofabrication: reappraising the definition of an evolving field. Groll J, Boland T, Blunk T, Burdick JA, Cho DW, Dalton PD, Derby B, Forgacs G, Li Q, Mironov VA, Moroni L, Nakamura M, Shu W, Takeuchi S, Vozzi G, Woodfield TB, Xu T, Yoo JJ, Malda J.. Biofabrication. 2016;8(1):013001.

Investigation of thermal degradation with extrusion-based dispensing modules for 3D bioprinting technology. Lee H, Yoo JJ, Kang HW, Cho DW.. Biofabrication. 2016;8(1):015011.

Production of tissue engineered heart valves. Atala A, Yoo J, inventors; Wake Forest University Health Sciences, assignee.. European patent office EP 1863546. 2015 Oct 7; United States patent 9,248,015. 2016 Feb 2. 2016;():.

Oxygen-generating compositions for enhancing cell and tissue survival in vivo. Harrison B, Yoo J, Atala A, inventors; Wake Forest University Health Sciences, assignee.. European patent office EP 2155235. 2016 Apr 6; Japan patent JP2 5926758. 2016 Apr 28. 2016;():.

Tissue engineered blood vessels. Atala A, Soker S, Yoo J, inventors; Wake Forest University Health Sciences, assignee.. European patent office EP 1863547. 2016 May 11. 2016;():.

Inkjet printing of tissues and cells. Xu T, Yoo J, Atala A, inventors; Wake Forest University Health Sciences, assignee.. United States patent US 9,301,925. 2016 Apr 5. 2016;():.

Pore size impacts hypertropic scarring-related outcomes in 3D printed polyurethane scaffolds [abstract]. Lorden E, Ramchal T, Chandra P, Bashirov L, Ibrahim MM, Hammett E, Klitzman B, Yoo J, Levison H, Lee S, Leong K.. Wound Repair Regen. 2016;24(2):A16-A17.

Penile urethra replacement with autologous cell-seeded tubularized collagen matrices. De Filippo RE, Kornitzer BS, Yoo JJ, Atala A.. J Tissue Eng Regen Med. 2015;9(3):257-264.

Pdx1 and controlled culture conditions induced differentiation of human amniotic fluid-derived stem cells to insulin-producing clusters. Chun SY, Mack DL, Moorefield E, Oh SH, Kwon TG, Pettenati MJ, Yoo JJ, Coppi PD, Atala A, Soker S.. J Tissue Eng Regen Med. 2015;9(5):540-549.

Bioengineered transplantable porcine livers with re-endothelialized vasculature. Ko IK, Peng L, Peloso A, Smith CJ, Dhal A, Deegan DB, Zimmerman C, Clouse C, Zhao W, Shupe TD, Soker S, Yoo JJ, Atala A.. Biomaterials. 2015;40():72-79.

Manufacturing road map for tissue engineering and regenerative medicine technologies. Hunsberger J, Harrysson O, Shirwaiker R, Starly B, Wysk R, Cohen P, Allickson J, Yoo J, Atala A.. Stem Cells Transl Med. 2015;4(2):130-135.

Engineered small diameter vascular grafts by combining cell sheet engineering and electrospinning technology. Ahn H, Ju YM, Takahashi H, Williams DF, Yoo JJ, Lee SJ, Okano T, Atala A.. Acta Biomater. 2015;16():14-22.

The dose-effect safety profile of skeletal muscle precursor cell therapy in a dog model of intrinsic urinary sphincter deficiency. Williams JK, Eckman D, Dean A, Moradi M, Allickson J, Cline JM, Yoo JJ, Atala A.. Stem Cells Transl Med. 2015;4(3):286-294.

Pre-clinical efficacy and safety evaluation of human amniotic fluid-derived stem cell injection in a mouse model of urinary incontinence. Choi JY, Chun SY, Kim BS, Kim HT, Yoo ES, Shon YH, Lim JO, Yun SJ, Song PH, Chung SK, Yoo JJ, Kwon TG.. Yonsei Med J. 2015;56(3):648-657.

Fabrication and characterization techniques for decellularized organ scaffolds. Chun SY, Oh SH, Yoo JJ, Kwon TG.. Tissue Eng Regen Med. 2015;12(Suppl 1):1-10.

Whole kidney engineering for clinical translation. Kim IH, Ko IK, Atala A, Yoo JJ.. Curr Opin Organ Transplant. 2015;20(2):165-170.

Autologously generated tissue-engineered bone flaps for reconstruction of large mandibular defects in an ovine model. Tatara AM, Kretlow JD, Spicer PP, Lu S, Lam J, Liu W, Cao Y, Liu G, Jackson JD, Yoo JJ, Atala A, van den Beucken JJ, Jansen JA, Kasper FK, Ho T, Demian N, Miller MJ, Wong ME, Mikos AG.. Tissue Eng Part A. 2015;21(9-10):1520-1528.

Production of tissue engineered digits and limbs. Atala AJ, Yoo JJ, Grace L, Lim G, Lee SJ, inventors; Wake Forest University Health Sciences, assignee.. United States patent US 9,039,782. 2015 May 26. 2015;():.

Medical devices incorporating collagen inhibitors. Atala AJ, Hodges SJ, Sullivan CA, Yoo JJ, inventors; Wake Forest University Health Sciences, assignee.. Germany patent DE 2101834. 2015 Mar 25 (patent also held in European Patent Office, France, and Greece). 2015;():.

Inkjet gene printing. Xu T, Yoo JJ, Atala AJ, inventors; Wake Forest University Health Sciences, assignee.. United States patent US 9,045,757. 2015 June 2. 2015;():.

Inkjet printing of tissues and cells. Xu T, Yoo JJ, Atala AJ, Dice D, inventors; Wake Forest University Health Sciences, assignee.. United States patent US 9,005,972. 2015 Apr 4. 2015;():.

Peroxide-based oxygen generating topical wound dressing for enhancing healing of dermal wounds. Chandra PK, Ross CL, Smith LC, Jeong SS, Kim J, Yoo JJ, Harrison BS.. Wound Repair Regen. 2015;23(6):830-841.

Cell-based therapy for kidney disease. Chung HC, Ko IK, Atala A, Yoo JJ.. Korean J Urol. 2015;56(6):412-421.

A 3D bioprinted complex structure for engineering the muscle-tendon unit. Merceron TK, Burt M, Seol YJ, Kang HW, Lee SJ, Yoo JJ, Atala A.. Biofabrication. 2015;7(3):035003.

A novel tissue-engineered trachea with a mechanical behavior similar to native trachea. Park JH, Hong JM, Ju YM, Jung JW, Kang HW, Lee SJ, Yoo JJ, Kim SW, Kim SH, Cho DW.. Biomaterials. 2015;62():106-115.

Functional recovery of denervated muscle by neurotization using nerve guidance channels. Kang SB, Ju YM, Lee SJ, Atala A, Yoo JJ.. J Tissue Eng Regen Med. 2015;9(7):838-846.

A hydrogel bioink toolkit for mimicking native tissue biochemical and mechanical properties in bioprinted tissue constructs. Skardal A, Devarasetty M, Kang HW, Mead I, Bishop C, Shupe T, Lee SJ, Jackson J, Yoo J, Soker S, Atala A.. Acta Biomater. 2015;25():24-34.

Characterization of CD133 antibody-directed recellularized heart valves. Williams JK, Miller ES, Lane MR, Atala A, Yoo JJ, Jordan JE.. J Cardiovasc Transl Res. 2015;8(7):411-420.

CD133 antibody conjugation to decellularized human heart valves intended for circulating cell capture. Vossler JD, Min Ju Y, Williams JK, Goldstein S, Hamlin J, Lee SJ, Yoo JJ, Atala A.. Biomed Mater. 2015;10(5):055001.

Bioprinting of organs for toxicology testing. Kang HW, Atala A, Yoo JJ. In: Atala A, Yoo JJ, eds. Essentials of 3D biofabrication and translation. London (UK): Elsevier/Academic Press;2015: 179-186.

Bioprinting of three-dimensional tissues and organ constructs. Seol YJ, Yoo JJ, Atala A. In: Atala A, Yoo JJ, eds. Essentials of 3D biofabrication and translation. London (UK): Elsevier/Academic Press;2015: 283-292.

Bioprinting of skin. Marco J, Atala A, Yoo JJ. In: Atala A, Yoo JJ, eds. Essentials of 3D biofabrication and translation. London (UK): Elsevier/Academic Press;2015: 371-378.

Human amniotic fluid derived stem cells improve renal function in a rodent model of chronic kidney disease (CKD) [abstract]. George S, Abolbashari M, Ko I, Atala A, Yoo JJ.. Tissue Eng Part A. 2015;21(Suppl 1):S165-S166.

In vivo myc gene delivery to adult mouse inner ear stimulates proliferation of post mitotic supporting cells leading to new hair cell formation [abstract]. Hassan S, Burns JC, Oliver ER, Kiell EP, Yoo JJ, Jackson JD, Atala AJ.. Tissue Eng Part A. 2015;21(Suppl 1):S114.

Fabrication of biomimetic vascular scaffolds using vascular corrosion casts for reconstruction of pre-vascularized engineered tissues [abstract]. Huling J, Ko I, Atala A, Yoo JJ.. Tissue Eng Part A. 2015;21(Suppl 1):S153-S154.

In vitro skin engineering for drug testing: reconstruction of 3D skin equivalents in vitro by bioprinting [abstract]. Jeong CG, Yoo JJ, Simmons CA, Seol Y, Klein JD, Moore JT, Atala A.. Tissue Eng Part A. 2015;21(Suppl 1):S322.

The effect of substrate elasticity on the function of ovarian follicles [abstract]. Joo S, Oh S, Sivanandane S, Opara E, Jackson J, Lee S, Yoo J, Atala A.. Tissue Eng Part A. 2015;21(Suppl 1):S30.

Functional vascular scaffolding system for reconstructing small diameter blood vessels [abstract]. Ju Y, Vossler J, Ahn H, Kim I, Yoo J, Atala A, Lee S.. Tissue Eng Part A. 2015;21(Suppl 1):S185.

Anti-CD133 antibody conjugation to decellularized human heart valves for endothelial progenitor cell capture [abstract]. Ju Y, Vossler JD, Goldstein S, Williams K, Lee S, Yoo JJ, Atala A.. Tissue Eng Part A. 2015;21(Suppl 1):S140.

Engineering of corporal tissue constructs using non-human primate/human corpus cavernosum smooth muscle and endothelial cells for clinical applications [abstract]. Ju Y, Ahn H, Somara S, Baume A, Dean A, Zambon J, Williams K, Allickson J, Yoo J, Atala A, Jackson J.. Tissue Eng Part A. 2015;21(Suppl 1):S207.

Bioprinted scaffolds for cartilage tissue engineering. Kang HW, Yoo JJ, Atala A.. Methods Mol Biol. 2015;1340():161-169.

3-D bioprinting of bone constructs for craniomaxillofacial reconstruction [abstract]. Kengla CV, Kim I, Seol Y, Yoo JJ, Atala A, Lee S.. Tissue Eng Part A. 2015;21(Suppl 1):S391.

Implantation of re-endothelialized porcine liver constructs for whole organ engineering [abstract]. Ko I, Li P, Pelso A, Smith C, Dhal A, Clouse C, Zhao W, Shupe T, Soker S, Yoo JJ, Atala A.. Tissue Eng Part A. 2015;21(Suppl 1):S85.

3-D bioprinting of tissue organoids for body-on-a-chip drug screening platform [abstract]. Seol Y, Kang H, Lee S, Jackson JD, Skardal A, Shupe T, Soker S, Bishop C, Yoo JJ, Atala A.. Tissue Eng Part A. 2015;21(Suppl 1):S369.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

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