Profile

James J. Yoo, M.D., Ph.D.

James J. Yoo, M.D., Ph.D.

Professor, Institute for Regenerative Medicine
Translational Science Institute
Center for Biomolecular Imaging
Women's Health Center of Excellence for Research, Leadership, Education
Translational Science Institute
Physiology & Pharmacology

Contact Information

Academic: 336-713-7294 | Department: 336-716-2011

Email: jyoo@wakehealth.edu

Education & Training

  • B.A., University of Illinois-Urbana/Champaign , 1984
  • M.D., Korea University Medical College-Korea , 1989
  • Ph.D., Korea University Medical College-Korea , 1994
  • M.S., Korea University Medical College-Korea , 1992
  • Fellowship, Harvard Medical School, 1996
James J. Yoo, M.D., Ph.D.

James J. Yoo, M.D., Ph.D.

Professor, Institute for Regenerative Medicine Translational Science Institute
Center for Biomolecular Imaging
Women's Health Center of Excellence for Research, Leadership, Education
Translational Science Institute
Physiology & Pharmacology

Research Interests

biotechnology, degenerative disorders, engineering/bioengineering

Contact Information

Academic: 336-713-7294 | Department: 336-716-2011

Email: jyoo@wakehealth.edu

Recent Publications

Xu T, Zhao W, Zhu JM, Albanna MZ, Yoo JJ, Atala A. Complex heterogeneous tissue constructs containing multiple cell types prepared by inkjet printing technology. Biomaterials. 2013;34(1):130-139.

Sittadjody S, Saul JM, Joo S, Yoo JJ, Atala A, Opara EC. Engineered multilayer ovarian tissue that secretes sex steroids and peptide hormones in response to gonadotropins. Biomaterials. 2013;34(10):2412-2420.

Arenas-Herrera JE, Ko IK, Atala A, Yoo JJ. Decellularization for whole organ bioengineering. Biomed Mater. 2013;8(1):014106.

Orabi H, AbouShwareb T, Zhang Y, Yoo JJ, Atala A. Cell-seeded tubularized scaffolds for reconstruction of long urethral defects: a preclinical study. Eur Urol. 2013;63(3):531-538.

Hwang CM, Ay B, Kaplan DL, Rubin JP, Marra KG, Atala A, Yoo JJ, Lee SJ. Assessments of injectable alginate particle-embedded fibrin hydrogels for soft tissue reconstruction. Biomed Mater. 2013;8(1):014105.




Bellas E, Panilaitis BJ, Glettig DL, Kirker-Head CA, Yoo JJ, Marra KG, Rubin JP, Kaplan DL. Sustained volume retention in vivo with adipocyte and lipoaspirate seeded silk scaffolds. Biomaterials. 2013;34(12):2960-2968.

Ko IK, Ju YM, Chen T, Atala A, Yoo JJ, Lee SJ. Combined systemic and local delivery of stem cell inducing/recruiting factors for in situ tissue regeneration. FASEB J. 2012;26(1):158-168.

Jordan JE, Williams JK, Lee S-J, Raghavan D, Atala A, Yoo JJ. Bioengineered self-seeding heart valves. J Thorac Cardiovasc Surg. 2012;143(1):201-208.

Joo S, Ko IK, Atala A, Yoo JJ, Lee SJ. Amniotic fluid-derived stem cells in regenerative medicine research. Arch Pharm Res. 2012;35(2):271-280.

Sohn MY, Seo JM, Cho HJ, Suh JS, Seong WJ, Park IS, Atala A, Yoo JJ, Shon YH. Effective in vitro expansion of amniotic fluid-derived stem cells in serum free medium. Tissue Eng Regen Med. 2012;9(1):A48-A54.

Orlando G, Mirmalek-Sani SH, Sullivan DC, Farney A, Iskandar S, Abouschwareb T [sic] [Aboushwareb T], Arenas-Herrera J, Ko IK, Agcaoili S, Yoo JJ, Atala A, Stratta RJ, Soker S. Production and implantation of renal extracellular matrix scaffolds from porcine kidneys as a platform for renal bioengineering [abstract]. Am J Transplant. 2012;12(Suppl 2):94.

Orlando G, Wood KJ, De Coppi P, Baptista PM, Binder KW, Bitar KN, Breuer C, Burnett L, Christ G, Farney A, Figliuzzi M, Holmes JH IV, Koch K, Macchiarini P, Mirmalek Sani S-H, Opara E, Remuzzi A, Rogers J, Saul JM, Seliktar D,. Regenerative medicine as applied to general surgery. Ann Surg. 2012;255(5):867-880.

Mack DL, Skardal A, Yoo J, Soker S. Bioprinted amniotic fluid-derived stem cells accelerate wound healing in skin [abstract]. Mol Ther. 2012;20(Suppl 1):S285.

Rodrigues MT, Lee B-K, Lee SJ, Gomes ME, Reis RL, Atala A, Yoo JJ. The effect of differentiation stage of amniotic fluid stem cells on bone regeneration. Biomaterials. 2012;33(26):6069-6078.




Zhao Q, Lu B, George SK, Yoo JJ, Atala A. Safeguarding pluripotent stem cells for cell therapy with a non-viral, non-integrating episomal suicide construct. Biomaterials. 2012;33(29):7261-7271.

Orlando G, Farney AC, Iskandar SS, Mirmalek-Sani S-H, Sullivan DC, Moran E, AbouShwareb T, De Coppi P, Wood KJ, Stratta RJ, Atala A, Yoo JJ, Soker S. Production and implantation of renal extracellular matrix scaffolds from porcine kidneys as a platform for renal bioengineering investigations. Ann Surg. 2012;256(2):363-370.

Sullivan DC, Mirmalek-Sani SH, Deegan DB, Baptista PM, Aboushwareb T, Atala A, Yoo JJ. Decellularization methods of porcine kidneys for whole organ engineering using a high-throughput system. Biomaterials. 2012;33(31):7756-7764.

Guimaraes-Souza NK, Yamaleyeva LM, AbouShwareb T, Atala A, Yoo JJ. In vitro reconstitution of human kidney structures for renal cell therapy. Nephrol Dial Transplant. 2012;27(8):3082-3090.

Tillman BW, Yazdani SK, Neff LP, Corriere MA, Christ GJ, Soker S, Atala A, Geary RL, Yoo JJ. Bioengineered vascular access maintains structural integrity in response to arteriovenous flow and repeated needle puncture. J Vasc Surg. 2012;56(3):783-793.

Agcaoili SM, Aboushwareb T, Jackson JD, Atala A, Yoo JJ. Repopulation of primary renal cells for whole organ engineering [abstract]. J Tissue Eng Regen Med. 2012;6(Suppl 1):126.

Albanna MZ, Murphy S, Zhao W, El-Amin IB, Tan J, Jackson JD, Atala A, Yoo JJ. In situ bioprinting of autologous skin cells accelerates skin regeneration [abstract]. J Tissue Eng Regen Med. 2012;6(Suppl 1):94.

George SK, Gyabaah K, Abolbashari M, Kim C, Jackson JD, Aboushwareb T, Atala A, Yoo JJ. The feasibility of using autologous renal cells from diseased kidneys for the treatment of renal failure [abstract]. J Tissue Eng Regen Med. 2012;6(Suppl 1):127.

Gyabaah K, Aboushwareb T, Guimaraes Souza N, Yamaleyeva L, Varner A, Wang HJ, Atala A, Yoo JJ. Controlled regulation of erythropoietin by primary cultured renal cells for renal failure induced anemia. J Urol. 2012;188(5):2000-2006.

Hwang CM, Atala A, Yoo J, Jackson J, Lee SJ. A porous injectable hydrogel system for soft tissue regeneration [abstract]. J Tissue Eng Regen Med. 2012;6(Suppl 1):158.

Joo S, Helms A, Sivanandane S, Jackson JD, Soker S, Lee SJ, Atala A, Opara E, Yoo JJ. Development of ovarian follicle-like structures [abstract]. J Tissue Eng Regen Med. 2012;6(Suppl 1):131.

Kang SB, Olson JL, Atala A, Yoo JJ. Functional recovery of completely denervated muscle: implications for innervation of tissue-engineered muscle. Tissue Eng Part A. 2012;18(17-18):1912-1920.

Kim J, Hwang A, Khouri R, Andersson K-E, Lee SJ, Jackson J, Atala A, Yoo J. Down-regulation of cellular metabolism improves cell survival under hypoxic conditions [abstract]. J Tissue Eng Regen Med. 2012;6(Suppl 1):275.

Ko IK, Ju YM, DeLeon J, Atala A, Yoo JJ, Lee SJ. Combined systemic and local delivery of stem cell recruitment for in situ tissue regeneration [abstract]. J Tissue Eng Regen Med. 2012;6(Suppl 1):116.

Ko IK, Mirmalek-Sani S-H, Aboushwareb T, Atala A, Soker S, Yoo J. Re-endothelialization of acellular kidney scaffolds for whole organ engineering [abstract]. J Tissue Eng Regen Med. 2012;6(Suppl 1):128.

Lee BK, Ju YM, Cho JG, Jackson JD, Lee SJ, Atala A, Yoo JJ. End-to-side neurorrhaphy using an electrospun PCL/collagen nerve conduit for complex peripheral motor nerve regeneration. Biomaterials. 2012;33(35):9027-9036.

Lim LHJ, Yoo YJJ [sic] [Yoo JJ], Jo JI, Lim LJO. Restored skeletal muscle function from hydrogel and cell injection [abstract]. J Tissue Eng Regen Med. 2012;6(Suppl 1):412.

Mirmalek-Sani SH, Deegan DB, Sullivan DC, Ko I, George SK, Jackson JD, Aboushwareb TA, Atala A, Yoo J. Optimizing decellularization of porcine kidneys for whole organ bioengineering [abstract]. J Tissue Eng Regen Med. 2012;6(Suppl 1):172.

Shon H, Cho HJ, Lee SH, Suh JS, Yoo J. Cryopreservation of bone marrow-derived stem cells using natural cryoprotectants [abstract]. J Tissue Eng Regen Med. 2012;6(Suppl 1):364-365.

Shon Y, Sohn MY, Seo JM, Cho HJ, Lee SH, Suh JS, Yoo J. Short-term serum-free culture of amniotic fluid-derived stem cells [abstract]. J Tissue Eng Regen Med. 2012;6(Suppl 1):407.

Sivanandane S, Saul J, Joo S, Pareta R, Arenas J, Marshall N, Yoo J, Atala A, Opara E. Encapsulated ovarian endocrine cells produced sustained levels of steroid hormones in vivo [abstract]. J Tissue Eng Regen Med. 2012;6(Suppl 1):410.

Williams J, Badra S, Yoo J. Cell therapy for the treatment of neurogenic urinary incontinence (UI) in female nonhuman primates [abstract]. J Tissue Eng Regen Med. 2012;6(Suppl 1):125-126.

Yoo J. Keynote: animal models for translational research [abstract]. J Tissue Eng Regen Med. 2012;6(Suppl 1):394.

Yoo J. Keynote: changing perspectives on translational research [abstract]. J Tissue Eng Regen Med. 2012;6(Suppl 1):409.

Agcaoili SM, Aboushwareb T, Jackson JD, Yoo JJ, Atala A. Repopulation of primary renal cells for whole organ engineering [abstract]. J Am Coll Surg. 2012;215(3 Suppl):S142-S143.

Albanna MZ, Murphy S, Zhao W, El-Amin IB, Tan J, Dice DD, Kang H-W, Jackson JD, Yoo JJ, Atala A. In situ bioprinting of skin for reconstruction [abstract]. J Am Coll Surg. 2012;215(3 Suppl):S87.

Arenas JE, Ahn H, Hill TK, Young JM, Chang H, Yoo J, Lee SJ. Dual seeded polycaprolactone (PCL)/collagen electrospun vascular scaffold for engineering small diameter blood vessel and clinical translation [abstract]. J Am Coll Surg. 2012;215(3 Suppl):S139-S140.


Joo S, Sivanandane S, Opara EC, Jackson JD, Yoo JJ, Atala A. In vitro generation of three-dimensional functional ovarian structures [abstract]. J Am Coll Surg. 2012;215(3 Suppl):S65.

Lee B, JU YM, Cho J, Lee SJ, Jackson JD, Yoo JJ, Atala A. Use of a neighboring uninjured nerve for restoration of tissue function [abstract]. J Am Coll Surg. 2012;215(3 Suppl):S145.

Skardal A, Mack D, Kapetanovic E, Atala A, Jackson JD, Yoo J, Soker S. Bioprinted amniotic fluid-derived stem cells accelerate healing of large skin wounds. Stem Cells Transl Med. 2012;1(11):792-802.

Kim BS, Chun SY, Lee JK, Lim HJ, Bae JS, Chung HY, Atala A, Soker S, Yoo JJ, Kwon TG. Human amniotic fluid stem cell injection therapy for urethral sphincter regeneration in an animal model. BMC Med. 2012;10():94.

Wang HJ, Varner A, Aboushwareb T, Atala A, Yoo JJ. Ischemia/reperfusion-induced renal failure in rats as a model for evaluating cell therapies. Ren Fail. 2012;34(10):1324-1332.

Yamaleyeva LM, Guimaraes-Souza NK, Krane LS, Agcaoili S, Gyabaah K, Atala A, Aboushwareb T, Yoo JJ. Cell therapy with human renal cell cultures containing erythropoietin-positive cells improves chronic kidney injury. Stem Cells Transl Med. 2012;1(5):373-383.

Chun SY, Cho DH, Chae SY, Choi KH, Lim HJ, Yoon GS, Kim BS, Kim BW, Yoo JJ, Kwon TG. Human amniotic fluid stem cell-derived muscle progenitor cell therapy for stress urinary incontinence. J Korean Med Sci. 2012;27(11):1300-1307.

Rodrigues MT, Lee SJ, Gomes ME, Reis RL, Atala A, Yoo JJ. Amniotic fluid-derived stem cells as a cell source for bone tissue engineering. Tissue Eng Part A. 2012;18(23-24):2518-2527.

Ladd MR, Lee SJ, Stitzel JD, Atala A, Yoo JJ. Co-electrospun dual scaffolding system with potential for muscle-tendon junction tissue engineering. Biomaterials. 2011;32(6):1549-1559.

Komura M, Kim J, Atala A, Yoo JJ, Lee SJ. The digit: engineering of phalanges and small joints In: Atala A, Lanza R, Thomson JA, Nerem R, eds. Principles of regenerative medicine. 2nd ed. San Diego (CA): Academic Press;2011: 1091-1103.

Bae JH, Aboushwareb T, Atala A, Yoo JJ. Intracorporeal kidney support In: Atala A, Lanza R, Thomson JA, Nerem R, eds. Principles of regenerative medicine. 2nd ed. ;2011: 1105-1113.

Krane LS, Gorbachinsky I, Sirintrapun J, Yoo JJ, Atala A, Hodges SJ. Halofuginone-coated urethral catheters prevent periurethral spongiofibrosis in a rat model of urethral injury. J Endourol. 2011;25(1):107-112.

Lee SJ, Broda C, Atala A, Yoo JJ. Engineered cartilage covered ear implants for auricular cartilage reconstruction. Biomacromolecules. 2011;12(2):306-313.

Neff LP, Tillman BW, Yazdani SK, Machingal MA, Yoo JJ, Soker S, Bernish BW, Geary RL, Christ GJ. Vascular smooth muscle enhances functionality of tissue-engineered blood vessels in vivo. J Vasc Surg. 2011;53(2):426-434.

Raya-Rivera A, Esquiliano DR, Yoo JJ, Lopez-Bayghen E, Soker S, Atala A. Tissue-engineered autologous urethras for patients who need reconstruction: an observational study. Lancet. 2011;377(9772):1175-1182.

Soler R, Vianello A, Fullhase C, Wang Z, Atala A, Soker S, Yoo JJ, Williams JK. Vascular therapy for radiation cystitis. Neurourol Urodyn. 2011;30(3):428-434.

Eberli D, Atala A, Yoo JJ. One and four layer acellular bladder matrix for fascial tissue reconstruction. J Mater Sci Mater Med. 2011;22(3):741-751.

Orlando G, Wood KJ, Stratta RJ, Yoo JJ, Atala A, Soker S. Regenerative medicine and organ transplantation: past, present, and future. Transplantation. 2011;91(12):1310-1317.

Seo JM, Sohn MY, Suh JS, Atala A, Yoo JJ, Shon Y-H. Cryopreservation of amniotic fluid-derived stem cells using natural cryoprotectants and low concentrations of dimethylsulfoxide. Cryobiology. 2011;62(3):167-173.

Machingal MA, Corona BT, Walters TJ, Kesireddy V, Koval CN, Dannahower A, Zhao W, Yoo JJ, Christ GJ. A tissue-engineered muscle repair construct for functional restoration of an irrecoverable muscle injury in a murine model. Tissue Eng Part A. 2011;17(17-18):2291-2303.

Lang R, Stern MM, Smith L, Bharadwaj S, Baptista PM, Bergman CR, Soker S, Yoo JJ, Atala A, Zhang Y, et al. Three-dimensional culture of hepatocytes on porcine liver tissue-derived extracellular matrix. Biomaterials. 2011;32(29):7042-7052.

Kang T-Y, Kang H-W, Hwang CM, Lee SJ, Park J, Yoo JJ, Cho D-W. The realistic prediction of oxygen transport in a tissue-engineered scaffold by introducing time-varying effective diffusion coefficients. Acta Biomater. 2011;7(9):3345-3353.

Raya-Rivera A, Esquiliano DR, Yoo JJ, Lopez-Bayghen E, Atala A. Cell-based tissue-engineered urethras [reply to letter]. Lancet. 2011;378(9791):569.

Moorefield EC, McKee EE, Solchaga L, Orlando G, Yoo JJ, Walker S, Furth ME, Bishop CE. Cloned, CD117 selected human amniotic fluid stem cells are capable of modulating the immune response. PLoS ONE. 2011;6(10):e26535.

Olson JL, Atala A, Yoo JJ. Tissue engineering: current strategies and future directions. Chonnam Med J. 2011;47(1):1-13.

Yoo JJ, Olson J, Atala A, Kim B. Regenerative medicine strategies for treating neurogenic bladder. Int Neurourol J. 2011;15(3):109-119.

Yamaleyeva LM, Guimaraes-Souza NK, Krane LS, Atala A, Aboushwareb T, Yoo JJ. A novel cell therapy approach for the treatment of chronic kidney injury using human renal cell cultures containing erythropoietin- and CD133/CD24-positive cells [abstract]. Hypertension. 2011;58(5):e160.

Rodrigues MT, Lee BK, Shiner T, Lee SJ, Atala A, Yoo J, Gomes ME, Reis RL. The effect of the differentiation stage of amniotic fluid stem cells seeded onto biodegradable scaffolds in the regeneration of non-union defects [abstract]. Int J Artif Organs. 2011;34(8):611-612.

Yang T-L, Yoo JJ, Siemionow MZ, Atala A. Tissue engineering for facial reconstruction In: Siemionow MZ, ed. The know-how of face transplantation. New York: Springer;2011: 447-464.

Yoo JJ, Joraku A, Atala A. Intracorporeal kidney support In: Atala A, Lanza R, Thomson JA, Nerem RM, eds. Foundations of regenerative medicine: clinical and therapeutic applications. Boston (MA): Academic Press/Elsevier;2010: 576-583.

Komura M, Eberli D, Yoo JJ, Atala A. Phalanges and small joints In: Atala A, Lanza R, Thomson JA, Nerem RM, eds. Foundations of regenerative medicine: clinical and therapeutic applications. Boston (MA): Academic Press/Elsevier;2010: 622-629.

Chen K-L, Eberli D, Yoo JJ, Atala A. Bioengineered corporal tissue for structural and functional restoration of the penis. Proc Natl Acad Sci U S A. 2010;107(8):3346-3350.

Bae JH, Yoo JJ. Cell-based therapy for urinary incontinence. Korean J Urol. 2010;51(1):1-7.

Hodges SJ, Yoo JJ, Mishra N, Atala A. The effect of epigenetic therapy on congenital neurogenic bladders--a pilot study. Urology. 2010;75(4):868-872.

Eberli D, Rodriguez S, Atala A, Yoo JJ. In vivo evaluation of acellular human dermis for abdominal wall repair. J Biomed Mater Res A. 2010;93(4):1527-1538.

Ju YM, Choi JS, Atala A, Yoo JJ, Lee SJ. Bilayered scaffold for engineering cellularized blood vessels. Biomaterials. 2010;31(15):4313-4321.

Kim JY, Jin G-Z, Park IS, Kim J-N, Chun SY, Park EK, Kim S-Y, Yoo J, Kim S-H, Rhie J-W, et al. Evaluation of solid free-form fabrication-based scaffolds seeded with osteoblasts and human umbilical vein endothelial cells for use in vivo osteogenesis. Tissue Eng Part A. 2010;16(7):2229-2236.

Choi JH, Gimble JM, Lee K, Marra KG, Rubin JP, Yoo JJ, Vunjak-Novakovic G, Kaplan DL. Adipose tissue engineering for soft tissue regeneration. Tissue Eng Part B Rev. 2010;16(4):413-426.

Yamaleyeva LM, Guimaraes-Souza NK, Gyabaah K, Aboushwareb T, Atala A, Yoo JJ. Erythropoietin expression and regulation in human kidney cells: a novel cell therapy approach for anemia due to renal failure [abstract]. Am J Transplant. 2010;10(Suppl 4):115.

Neff LP, Tillman B, Yazadani S, Machinga M, Yoo J, Soker S, Bernishi B, Geary R, Christ G. Vascular smooth muscle enhances functionality of tissue engineered blood vessels in vivo [abstract]. J Vasc Surg. 2010;51(Suppl):4S.

Aboushwareb T, Gyabaah K, Guimaraes-Souza N, Atala A, Yoo J. Controlled regulation of erythropoietin producing cells for renal failure induced anemia [abstract]. J Am Coll Surg. 2010;211(3 Suppl):S94.

Berry JL, Steen JA, Williams JK, Jordan JE, Atala A, Yoo JJ. Bioreactors for development of tissue engineered heart valves. Ann Biomed Eng. 2010;38(11):3272-3279.

Binder KW, Zhao WX, Aboushwareb T, Dice D, Atala A, Yoo JJ. In situ bioprinting of the skin for burns [abstract]. J Am Coll Surg. 2010;211(3 Suppl):S76.

Ju YM, Choi JS, Aboushwareb T, Atala A, Yoo J, Lee SJ. Bilayered vascular scaffolds for engineering cellularized small diameter blood vessels [abstract]. J Am Coll Surg. 2010;211(3 Suppl):S144-S145.

Kang SB, Aboushwareb T, Atala A, Yoo JJ. Functional recovery of completely denervated muscle by direct nerve transplantation [abstract]. J Am Coll Surg. 2010;211(3 Suppl):S87-S88.

Zhao WX, Xu T, Aboushwareb T, Atala A, Yoo J. In vivo generation of functional tissues using the inkjet printing technology for reconstructive surgery [abstract]. J Am Coll Surg. 2010;211(3 Suppl):S87.

Eberli D, Filho LF, Atala A, Yoo JJ. Composite scaffolds for the engineering of hollow organs and tissues. Methods. 2009;47(2):109-115.

Eberli D, Soker S, Atala A, Yoo JJ. Optimization of human skeletal muscle precursor cell culture and myofiber formation in vitro. Methods. 2009;47(2):98-103.

Tillman BW, Yazdani SK, Lee SJ, Geary RL, Atala A, Yoo JJ. The in vivo stability of electrospun polycaprolactone-collagen scaffolds in vascular reconstruction. Biomaterials. 2009;30(4):583-588.

Oh SH, Ward CL, Atala A, Yoo JJ, Harrison BS. Oxygen generating scaffolds for enhancing engineered tissue survival. Biomaterials. 2009;30(5):757-762.

Xu T, Rohozinski J, Zhao W, Moorefield EC, Atala A, Yoo JJ. Inkjet-mediated gene transfection into living cells combined with targeted delivery. Tissue Eng Part A. 2009;15(1):95-101.

Atala A, Yoo JJ. Guest editors' introduction. Methods in tissue engineering [editorial]. Methods. 2009;47(2):79-80.

Joraku A, Stern KA, Atala A, Yoo JJ. In vitro generation of three-dimensional renal structures. Methods. 2009;47(2):129-133.

Koh CJ, Delo DM, Lee JW, Siddiqui MM, Lanza RP, Soker S, Yoo JJ, Atala A. Parthenogenesis-derived multipotent stem cells adapted for tissue engineering applications. Methods. 2009;47(2):90-97.

Jung SH, Kim SH, Yang JC, Hong HH, Kim HL, Kim W, Son Y, Lee SJ, van Dyke M, Yoo JJ, et al. [Effect of keratin/PLGA scaffold on the articular cartilage tissue engineering: in vivo test] [Korean]. Tissue Eng Regen Med. 2009;6(1-3):192-198.

Lee DJ, Steen J, Jordan JE, Kincaid EH, Kon ND, Atala A, Berry J, Yoo JJ. Endothelialization of heart valve matrix using a computer-assisted pulsatile bioreactor. Tissue Eng Part A. 2009;15(4):807-814.

Oh AY, Kim SH, Kim CM, Jung SH, Jeon NR, Hong HH, Lee SJ, van Dyke M, Yoo JJ, Lee DW, et al. [The effect of keratin/PLGA scaffold on neural differentiation of rat BMSCs] [Korean]. Tissue Eng Regen Med. 2009;6(1-3):112-118.

Ladd MR, Lee SJ, Atala A, Yoo JJ. Bioreactor maintained living skin matrix. Tissue Eng Part A. 2009;15(4):861-868.

Oh AY, Kim SH, Kim YT, Jeon NR, Yang JC, Lee SJ, Yoo JJ, van Dyke M, Shin HS, Rhee JM, et al. [A study on proliferation and phenotypical stability of Schwann cell on keratin/PLGA film] [Korean]. Polymer [Korea]. 2009;33(2):118-123.

Eberli D, Andersson KE, Yoo JJ, Atala A. A canine model of irreversible urethral sphincter insufficiency. BJU Int. 2009;103(2):248-253.

Tillman BW, Yazdani SK, Geary RL, Corriere MA, Atala A, Yoo JJ. Efficient recovery of endothelial progenitors for clinical translation. Tissue Eng Part C Methods. 2009;15(2):213-221.

Fuellhase C, Soler R, Andersson KE, Atala A, Yoo JJ. Generation of organized bladder tissue constructs using a novel hybrid printing system [abstract]. Eur Urol Suppl. 2009;8(4):186.

Orabi H, Yoo J, Atala A. Local responses after implantation of autologous bladder cell-seeded scaffolds for urinary tract reconstruction: a large animal model [abstract]. Eur Urol Suppl. 2009;8(4):187.

Soler R, Fuellhase C, Andersson KE, Yoo JJ. The effect of lamina propria cells on the growth of urothelial and smooth muscle cells [abstract]. Eur Urol Suppl. 2009;8(4):188.

Atala A, Yoo J, Lim G, Czerw R, Soker S, Stitzel J, inventors; Wake Forest University Health Sciences, assignee. Cell scaffold matrices with incorporated therapeutic agents. United States patent US 7,531,503. 2009 May 12. 2009;():.

Guimaraes-Souza NK, Aboushwareb T, Stern KA, Atala A, Yoo JJ. In vitro reconstitution of human kidney strucutes [sic] for renal failure [abstract]. Transpl Int. 2009;22(Suppl 2):350.

Guimaraes-Souza N, Aboushwareb T, Stern K, Atala A, Yoo J. In vitro reconstitution of human kidney structures for renal failure [abstract]. J Am Coll Surg. 2009;209(3):S128-S129.

Ladd MR, Aboushwareb TA, Lee SJ, Atala A, Yoo J. Integrated scaffolding system for the engineering of muscle-tendon junction [abstract]. J Am Coll Surg. 2009;209(3 Suppl):S62.

Lee DJ, Aboushwareb T, Steen J, Berry J, Kon ND, Atala A, Kincaid EH, Jordan JE, Yoo JJ. Reendothelialization of tissue engineered heart valves using endothelial progenitor cells from valvular disease patients: a feasibility study [abstract]. J Am Coll Surg. 2009;209(3 Suppl):S92.

Tillman BW, Aboushwareb TA, Yazdani SK, Geary RL, Corriere MA, Atala A, Yoo JJ. Efficient recovery of endothelial progenitors for clinical translation [abstract]. J Am Coll Surg. 2009;209(3 Suppl):S91.

Tillman BW, Aboushwareb TA, Yazdani SK, Lee SJ, Geary RL, Atala A, Yoo JJ. Electrospun vascular scaffolds as a bypass graft: a feasibility study in vivo [abstract]. J Am Coll Surg. 2009;209(3 Suppl):S140.

Christ GJ, Andersson K-E, Williams K, Zhao W, D'Agostino R Jr, Kaplan J, Aboushwareb T, Yoo J, Calenda G, Davies KP, et al. Smooth-muscle-specific gene transfer with the human Maxi-K channel improves erectile function and enhances sexual behavior in atherosclerotic cynomolgus monkeys. Eur Urol. 2009;56(6):1055-1066.

Lee SJ, Harrison B, Czerw R, Yoo JJ, Atala A, Lim JO. Regulated heparin release using novel quantum dots for potential application to vascular graft engineering. J Macromol Sci, Pure Appl Chem. 2009;46(12):1191-1198.

Hipp J, Andersson K-E, Kwon TG, Kwak EK, Yoo J, Atala A. Microarray analysis of exstrophic human bladder smooth muscle. BJU Int. 2008;101(1):100-105.

Yoo JJ, Joraku A, Atala A. Intracorporeal kidney support In: Atala A, Lanza R, Thomson JA, Nerem RM, eds. Principles of regenerative medicine. Boston (MA): Academic Press;2008: 1106-1113.

Komura M, Eberli D, Yoo JJ, Atala A. Phalanges and small joints In: Atala A, Lanza R, Thomson JA, Nerem RM, eds. Principles of regenerative medicine. Boston (MA): Academic Press;2008: 1198-1205.

Christ GJ, Andersson K-E, Williams K, Zhao W, D'Agostino R, Kaplan J, Aboushwareb T, Yoo J, Davies K, Melman A. MAXI-K gene transfer with a smooth muscle specific promoter enhances erectile function and sexual behaviour in atherosclerotic cynomolgous monkeys [abstract]. Eur Urol. 2008;7(3 Suppl):143.

Eberli D, Yoo J, Soker S, Atala A. Muscle progenitor cells for the restoration of irreversibly damaged sphincter function [abstract]. Eur Urol. 2008;7(3 Suppl):317.

Hipp JA, Hipp JD, Yoo JJ, Atala A, Andersson KE. Micro array analysis of bladder smooth muscle from patients with myelomeningocele [abstract]. Eur Urol. 2008;7(3):229.

Kwon TG, Yoo JJ, Atala A. Local and systemic effects of a tissue engineered neobladder in a canine cystoplasty model. J Urol. 2008;179(5):2035-2041.

Lee SJ, Oh SH, Liu J, Soker S, Atala A, Yoo JJ. The use of thermal treatments to enhance the mechanical properties of electrospun poly (epsilon-caprolactone) scaffolds. Biomaterials. 2008;29(10):1422-1430.

Moon DG, Christ G, Stitzel JD, Atala A, Yoo JJ. Cyclic mechanical preconditioning improves engineered muscle contraction. Tissue Eng Part A. 2008;14(4):473-482.

Xu T, Olson J, Zhao WX, Atala A, Zhu JM, Yoo JJ. Characterization of cell constructs generated with inkjet printing technology using in vivo magnetic resonance imaging. J Manuf Sci E-T ASME. 2008;130(2):.

Xu T, Kincaid H, Atala A, Yoo JJ. High-throughput production of single-cell microparticles using an inkjet printing technology. J Manuf Sci E-T ASME. 2008;130(2):.


Lee SJ, Liu J, Oh SH, Soker S, Atala A, Yoo JJ. Development of a composite vascular scaffolding system that withstands physiological vascular conditions. Biomaterials. 2008;29(19):2891-2898.

Aboushwareb T, Egydio F, Straker L, Gyabaah K, Atala A, Yoo JJ. Erythropoietin producing cells for potential cell therapy. World J Urol. 2008;26(4):295-300.

Connolly SS, Yoo JJ, Abouheba M, Soker S, McDougal WS, Atala A. Cavernous nerve regeneration using acellular nerve grafts. World J Urol. 2008;26(4):333-339.

Eberli D, Yoo J, Atala A. Acellular collagen matrix for fascial tissue reconstruction [abstract]. Tissue Eng Part A. 2008;14(5):805.

Joraku A, Atala A, Yoo JJ. Organized kidney tissue structures for the treatment of end stage renal disease [abstract]. Tissue Eng Part A. 2008;14(5):765.

Joraku A, Sullivan C, Yoo JJ, Atala A. Tissue engineering of functional salivary gland for replacement [abstract]. Tissue Eng Part A. 2008;14(5):921.

Komura M, Nomi M, Soker S, Yoo JJ, Atala A. Functional reconstruction of engineered digits [abstract]. Tissue Eng Part A. 2008;14(5):855.

Lee DJ, Tsangaris S, Baptista P, Jarajapu Y, Kincaid E, Kon N, Berry J, Soker S, Yoo JJ, Atala A. Circulating progenitor cells obtained from valvular disease patients: potential applications for engineering heart valves [abstract]. Tissue Eng Part A. 2008;14(5):824.

Lee SJ, Lee JW, Lim G, Atala A, Yoo JJ. Composite scaffolds for bone tissue regeneration [abstract]. Tissue Eng Part A. 2008;14(5):714.

Orabi HO, Tan J, Atala A, Yoo JJ. CT-assisted virtual endoscopy: an innovative imaging tool for the assessment of engineered tissue [abstract]. Tissue Eng Part A. 2008;14(5):832.

Xu T, Hipp J, Atala A, Yoo JJ, Van Dyke ME. Genomic guided ECM biomaterials development for regenerative medicine applications [abstract]. Tissue Eng Part A. 2008;14(5):739.

Xu T, Rohozinski J, Zhao W, Moorefield E, Atala A, Yoo JJ. Inkjet gene printing: a novel approach to achieve gene modified cells for tissue engineering [abstract]. Tissue Eng Part A. 2008;14(5):869-870.

Yoo JJ. Amniotic fluid-derived stem cells for regenerative medicine therapies [abstract]. Tissue Eng Part A. 2008;14(5):699.

Zhang YY, McNeill E, Soker S, Yoo JJ, Atala A. A novel cell source for urologic tissue reconstruction [abstract]. Tissue Eng Part A. 2008;14(5):697.

Atala A, Yoo JJ. Tissue engineering in urology [editorial]. World J Urol. 2008;26(4):293-294.

De Filippo RE, Bishop CE, Filho LF, Yoo JJ, Atala A. Tissue engineering a complete vaginal replacement from a small biopsy of autologous tissue. Transplantation. 2008;86(2):208-214.

Hipp JA, Hipp JD, Yoo JJ, Atala A, Andersson KE. Microarray analysis of bladder smooth muscle from patients with myelomeningocele. BJU Int. 2008;102(6):741-746.

Dorin RP, Pohl HG, DeFilippo RE, Yoo JJ, Atala A. Tubularized urethral replacement with unseeded matrices: what is the maximum distance for normal tissue regeneration?. World J Urol. 2008;26(4):323-326.

Kim B-S, Atala A, Yoo JJ. A collagen matrix derived from bladder can be used to engineer smooth muscle tissue. World J Urol. 2008;26(4):307-314.

Lee SJ, Van Dyke M, Atala A, Yoo JJ. Host cell mobilization for in situ tissue regeneration. Rejuvenation Res. 2008;11(4):747-756.

Raya-Rivera AM, Baez C, Atala A, Yoo JJ. Tissue engineered testicular prostheses with prolonged testosterone release. World J Urol. 2008;26(4):351-358.

Zhang Y, McNeill E, Tian H, Soker S, Andersson K-E, Yoo JJ, Atala A. Urine derived cells are a potential source for urological tissue reconstruction. J Urol. 2008;180(5):2226-2233.

Eberli D, Susaeta R, Yoo JJ, Atala A. A method to improve cellular content for corporal tissue engineering. Tissue Eng Part A. 2008;14(10):1581-1589.

Oh AY, Kim SH, Lee SJ, Yoo JJ, Van Dyke M, Rhee JM, Khang G. [Preparation and characterization of PLGA scaffold impregnated keratin for tissue engineering application] [Korean]. Polymer [Korea]. 2008;32(5):403-408.

Hong HH, Kim SH, Oh AY, Jeon NR, Jung SH, Lee SJ, Van Dyke M, Yoo JJ, Son Y, Rhee JM, et al. [Effect of keratin/PLGA hybrid scaffold for chondrogenesis: in vitro test] [Korean]. Tissue Eng Regen Med. 2008;5(4-6):861-868.

Oh AY, Kim SH, Jung SH, Hong HH, Jeon NR, Lee SJ, Van Dyke M, Yoo JJ, Rhee JM, Khang G. [Effect of keratin/PLGA scaffold on proliferation and phenotype of Schwann cell] [Korean]. Tissue Eng Regen Med. 2008;5(4-6):855-860.

De Coppi P, Bartsch G Jr, Siddiqui MM, Xu T, Santos CC, Perin L, Yoo JJ, Furth ME, Soker S, Atala A, et al. Isolation of amniotic stem cell lines with potential for therapy. Nat Biotechnol. 2007;25(1):100-106.

Joraku A, Sullivan CA, Yoo J, Atala A. In-vitro reconstitution of three-dimensional human salivary gland tissue structures. Differentiation. 2007;75(4):318-324.

Lee DJ, Tsangaris S, Baptista P, Jarajapu YPR, Kincaid E, Kon N, Berry J, Soker S, Yoo J, Atala A. Engineering of heart valves using circulating progenitor cells from patients with valvular disease--a feasibility study [abstract]. FASEB J. 2007;21(6):A975.

Van Dyke M, Oberpenning F, Meng J, Soker S, Yoo JJ, Atala A. Total organ replacement using tissue engineering [abstract]. FASEB J. 2007;21(5):A140.

Xu T, Zhao W, Zhu J-M, Atala A, Yoo JJ. Bio-printing of living organized tissues using an inkjet technology [abstract]. FASEB J. 2007;21(5):A636.

Zare S, Christ G, Moon DG, Zhao W, Atala A, Yoo JJ. Functional enhancement of bioreactor assisted engineered skeletal muscle [abstract]. FASEB J. 2007;21(5):A135.

Moon DG, Christ GJ, Stitzel J, Yoo JJ, Atala A. Tissue bioreactor system for the creation and maturation of organized functional tissues for surgical reconstruction [abstract]. J Urol. 2007;177(4 Suppl):58-59.

Rodriguez S, Chen KL, Christ GJ, Yoo JJ, Atala A. Progenitor cell-derived endothelial cell therapy restores diabetes associated erectile dysfunction [abstract]. J Urol. 2007;177(4 Suppl):264.

Chun SY, Lim GJ, Kwon TG, Kwak EK, Kim BW, Atala A, Yoo JJ. Identification and characterization of bioactive factors in bladder submucosa matrix. Biomaterials. 2007;28(29):4251-4256.

Harrison BS, Eberli D, Lee SJ, Atala A, Yoo JJ. Oxygen producing biomaterials for tissue regeneration. Biomaterials. 2007;28(31):4628-4634.

Eberli D, Yoo JJ, Atala A. A composite scaffold for the engineering of hollow organs and tissues [abstract]. Tissue Eng. 2007;13(7):1635.

Eberli D, Yoo JJ, Atala A. Fascial tissue reconstruction using acellular collagen matrix [abstract]. Tissue Eng. 2007;13(7):1695-1696.

Eberli D, Yoo J, Soker S, Atala A. Muscle progenitor cells for the restoration of irreversibly damaged sphincter function: a pre-clinical study [abstract]. Tissue Eng. 2007;13(7):1732-1733.

Egydio F, Moore P, Zhang Y, Atala A, Yoo JJ. Erythropoietin producing cells for the treatment of renal failure induced anemia [abstract]. Tissue Eng. 2007;13(7):1690.

Harrison BS, Eberli D, Lee SJ, Oh SH, Ward C, Atala A, Yoo JJ. Oxygen generating scaffolds for tissue regeneration [abstract]. Tissue Eng. 2007;13(7):1740.

Lee SJ, Van Dyke M, Atala A, Yoo JJ. Stem/progenitor cell mobilization for tissue regeneration [abstract]. Tissue Eng. 2007;13(7):1757.

Orabi HO, Aboushwareb T, Yoo JJ, Atala A. Tissue engineered tubularized urethra for surgical reconstruction: a pre-clinical study [abstract]. Tissue Eng. 2007;13(7):1769.

Rodriguez S, Chen KL, Atala A, Yoo JJ. Progenitor-derived endothelial cell therapy restores erectile function [abstract]. Tissue Eng. 2007;13(7):1747-1748.

Xu T, Zhao W, Atala A, Yoo J. In vivo generation of functional tissues using the inkjet printing technology [abstract]. Tissue Eng. 2007;13(7):1713-1714.

Zare S, Christ G, Moon DG, Zhao W, Atala A, Yoo JJ. Functional enhancement of bioreactor assisted engineered skeletal muscle [abstract]. Tissue Eng. 2007;13(7):1698.

Eberli D, Tillman B, Yoo J, Soker S, Atala A. Muscle progenitor cells for the restoration of irreversibly damaged sphincter function: a preclinical study. J Am Coll Surg. 2007;205(3 Suppl):S106.

Moon DG, Tillman B, Christ G, Stitzel J, Yoo J, Atala A. Tissue bioreactor system for the creation and maturation of organized functional tissues for surgical reconstruction [abstract]. J Am Coll Surg. 2007;205(3 Suppl):S104.

Eberli D, Susaeta R, Yoo JJ, Atala A. Tunica repair with acellular bladder matrix maintains corporal tissue function. Int J Impot Res. 2007;19(6):602-609.

Lee SJ, Yoo JJ, Lim GJ, Atala A, Stitzel J. In vitro evaluation of electrospun nanofiber scaffolds for vascular graft application. J Biomed Mater Res A. 2007;83(4):999-1008.

Amiel GE, Komura M, Shapira O, Yoo JJ, Yazdani S, Berry J, Kaushal S, Bischoff J, Atala A, Soker S. Engineering of blood vessels from acellular collagen matrices coated with human endothelial cells. Tissue Eng. 2006;12(8):2355-2365.

Yoo JJ, Kim Y-M, Yoon KS, Koo K-H, Kim JW, Nam KW, Kim HJ. Contemporary alumina-on-alumina total hip arthroplasty performed in patients younger than forty years: a 5-year minimum follow-up study. J Biomed Mater Res B Appl Biomater. 2006;78B(1):70-75.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Professor, Institute for Regenerative Medicine

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