Profile

James J. Yoo, M.D., Ph.D.Wake Forest School of Medicine

James J. Yoo, M.D., Ph.D.

Professor,



Contact Information

Academic: 336-713-7294 | Department: 336-716-2011

Email: jyoo@wakehealth.edu

Education & Training

  • B.A., University of Illinois-Urbana/Champaign, 1984
  • M.D., Korea University Medical College-Korea, 1989
  • M.S., Korea University Medical College-Korea, 1992
  • Ph.D., Korea University Medical College-Korea, 1994
  • Fellowship, Harvard Medical School, 1996
James J. Yoo, M.D., Ph.D.

James J. Yoo, M.D., Ph.D.

Professor, Institute for Regenerative Medicine
Office of Women in Medicine and Science
Physiology & Pharmacology
Translational Science Institute

Research Interests

biotechnology, cardiac function, cell growth, differentiation,d, critical/intensive care medici, engineering/bioengineering, surgery/trauma/burns/trauma, transplantation, vascular diseases, medical technology/devices

Contact Information

Academic: 336-713-7294 | Department: 336-716-2011

Email: jyoo@wakehealth.edu

Recent Publications

Abolbashari M, Agcaoili SM, Lee MK, Ko IK, Aboushwareb T, Jackson JD, Yoo JJ, Atala A. Repopulation of porcine kidney scaffold using porcine primary renal cells. Acta Biomater. 2016;29():52-61.

Kim N, Yoo JJ, Atala A, Lee SJ. Combination of small RNAs for skeletal muscle regeneration. FASEB J. 2016;30(3):1198-1206.

Huling J, Ko IK, Atala A, Yoo JJ. Fabrication of biomimetic vascular scaffolds for 3D tissue constructs using vascular corrosion casts. Acta Biomater. 2016;32():190-197.

Kang HW, Lee SJ, Ko IK, Kengla C, Yoo JJ, Atala A. A 3D bioprinting system to produce human-scale tissue constructs with structural integrity. Nat Biotechnol. 2016;34(3):312-319.

Rubin JP, Gurtner GC, Liu W, March KL, Seppanen-Kaijansinkko R, Yaszemski MJ, Yoo JJ. Surgical therapies and tissue engineering: at the intersection between innovation and regulation [editorial]. Tissue Eng Part A. 2016;22(5-6):397-400.

De Filippo RE, Kornitzer BS, Yoo JJ, Atala A. Penile urethra replacement with autologous cell-seeded tubularized collagen matrices. J Tissue Eng Regen Med. 2015;9(3):257-264.

Chun SY, Mack DL, Moorefield E, Oh SH, Kwon TG, Pettenati MJ, Yoo JJ, Coppi PD, Atala A, Soker S. Pdx1 and controlled culture conditions induced differentiation of human amniotic fluid-derived stem cells to insulin-producing clusters. J Tissue Eng Regen Med. 2015;9(5):540-549.

Ko IK, Peng L, Peloso A, Smith CJ, Dhal A, Deegan DB, Zimmerman C, Clouse C, Zhao W, Shupe TD, Soker S, Yoo JJ, Atala A. Bioengineered transplantable porcine livers with re-endothelialized vasculature. Biomaterials. 2015;40():72-79.

Hunsberger J, Harrysson O, Shirwaiker R, Starly B, Wysk R, Cohen P, Allickson J, Yoo J, Atala A. Manufacturing road map for tissue engineering and regenerative medicine technologies. Stem Cells Transl Med. 2015;4(2):130-135.

Ahn H, Ju YM, Takahashi H, Williams DF, Yoo JJ, Lee SJ, Okano T, Atala A. Engineered small diameter vascular grafts by combining cell sheet engineering and electrospinning technology. Acta Biomater. 2015;16():14-22.

Williams JK, Eckman D, Dean A, Moradi M, Allickson J, Cline JM, Yoo JJ, Atala A. The dose-effect safety profile of skeletal muscle precursor cell therapy in a dog model of intrinsic urinary sphincter deficiency. Stem Cells Transl Med. 2015;4(3):286-294.

Choi JY, Chun SY, Kim BS, Kim HT, Yoo ES, Shon YH, Lim JO, Yun SJ, Song PH, Chung SK, Yoo JJ, Kwon TG. Pre-clinical efficacy and safety evaluation of human amniotic fluid-derived stem cell injection in a mouse model of urinary incontinence. Yonsei Med J. 2015;56(3):648-657.

Chun SY, Oh SH, Yoo JJ, Kwon TG. Fabrication and characterization techniques for decellularized organ scaffolds. Tissue Eng Regen Med. 2015;12(Suppl 1):1-10.

Kim IH, Ko IK, Atala A, Yoo JJ. Whole kidney engineering for clinical translation. Curr Opin Organ Transplant. 2015;20(2):165-170.

Tatara AM, Kretlow JD, Spicer PP, Lu S, Lam J, Liu W, Cao Y, Liu G, Jackson JD, Yoo JJ, Atala A, van den Beucken JJ, Jansen JA, Kasper FK, Ho T, Demian N, Miller MJ, Wong ME, Mikos AG. Autologously generated tissue-engineered bone flaps for reconstruction of large mandibular defects in an ovine model. Tissue Eng Part A. 2015;21(9-10):1520-1528.

Atala AJ, Yoo JJ, Grace L, Lim G, Lee SJ, inventors; Wake Forest University Health Sciences, assignee. Production of tissue engineered digits and limbs. United States patent US 9,039,782. 2015 May 26. 2015;():.

Atala AJ, Hodges SJ, Sullivan CA, Yoo JJ, inventors; Wake Forest University Health Sciences, assignee. Medical devices incorporating collagen inhibitors. Germany patent DE 2101834. 2015 Mar 25 (patent also held in European Patent Office, France, and Greece). 2015;():.

Xu T, Yoo JJ, Atala AJ, inventors; Wake Forest University Health Sciences, assignee. Inkjet gene printing. United States patent US 9,045,757. 2015 June 2. 2015;():.

Xu T, Yoo JJ, Atala AJ, Dice D, inventors; Wake Forest University Health Sciences, assignee. Inkjet printing of tissues and cells. United States patent US 9,005,972. 2015 Apr 4. 2015;():.

Chandra PK, Ross CL, Smith LC, Jeong SS, Kim J, Yoo JJ, Harrison BS. Peroxide-based oxygen generating topical wound dressing for enhancing healing of dermal wounds. Wound Repair Regen. 2015;23(6):830-841.

Chung HC, Ko IK, Atala A, Yoo JJ. Cell-based therapy for kidney disease. Korean J Urol. 2015;56(6):412-421.

Merceron TK, Burt M, Seol YJ, Kang HW, Lee SJ, Yoo JJ, Atala A. A 3D bioprinted complex structure for engineering the muscle-tendon unit. Biofabrication. 2015;7(3):035003.

Park JH, Hong JM, Ju YM, Jung JW, Kang HW, Lee SJ, Yoo JJ, Kim SW, Kim SH, Cho DW. A novel tissue-engineered trachea with a mechanical behavior similar to native trachea. Biomaterials. 2015;62():106-115.

Moon KH, Ko IK, Yoo JJ, Atala A. Kidney diseases and tissue engineering. Methods. 2015;():.

Kang SB, Ju YM, Lee SJ, Atala A, Yoo JJ. Functional recovery of denervated muscle by neurotization using nerve guidance channels. J Tissue Eng Regen Med. 2015;9(7):838-846.

Skardal A, Devarasetty M, Kang HW, Mead I, Bishop C, Shupe T, Lee SJ, Jackson J, Yoo J, Soker S, Atala A. A hydrogel bioink toolkit for mimicking native tissue biochemical and mechanical properties in bioprinted tissue constructs. Acta Biomater. 2015;25():24-34.

Williams JK, Miller ES, Lane MR, Atala A, Yoo JJ, Jordan JE. Characterization of CD133 antibody-directed recellularized heart valves. J Cardiovasc Transl Res. 2015;8(7):411-420.

Vossler JD, Min Ju Y, Williams JK, Goldstein S, Hamlin J, Lee SJ, Yoo JJ, Atala A. CD133 antibody conjugation to decellularized human heart valves intended for circulating cell capture. Biomed Mater. 2015;10(5):055001.

Kang HW, Atala A, Yoo JJ. Bioprinting of organs for toxicology testing In: Atala A, Yoo JJ, eds. Essentials of 3D biofabrication and translation. London (UK): Elsevier/Academic Press;2015: 179-186.

Seol YJ, Yoo JJ, Atala A. Bioprinting of three-dimensional tissues and organ constructs In: Atala A, Yoo JJ, eds. Essentials of 3D biofabrication and translation. London (UK): Elsevier/Academic Press;2015: 283-292.

Marco J, Atala A, Yoo JJ. Bioprinting of skin In: Atala A, Yoo JJ, eds. Essentials of 3D biofabrication and translation. London (UK): Elsevier/Academic Press;2015: 371-378.

George S, Abolbashari M, Ko I, Atala A, Yoo JJ. Human amniotic fluid derived stem cells improve renal function in a rodent model of chronic kidney disease (CKD) [abstract]. Tissue Eng Part A. 2015;21(Suppl 1):S165-S166.

Hassan S, Burns JC, Oliver ER, Kiell EP, Yoo JJ, Jackson JD, Atala AJ. In vivo myc gene delivery to adult mouse inner ear stimulates proliferation of post mitotic supporting cells leading to new hair cell formation [abstract]. Tissue Eng Part A. 2015;21(Suppl 1):S114.

Huling J, Ko I, Atala A, Yoo JJ. Fabrication of biomimetic vascular scaffolds using vascular corrosion casts for reconstruction of pre-vascularized engineered tissues [abstract]. Tissue Eng Part A. 2015;21(Suppl 1):S153-S154.

Jeong CG, Yoo JJ, Simmons CA, Seol Y, Klein JD, Moore JT, Atala A. In vitro skin engineering for drug testing: reconstruction of 3D skin equivalents in vitro by bioprinting [abstract]. Tissue Eng Part A. 2015;21(Suppl 1):S322.

Joo S, Oh S, Sivanandane S, Opara E, Jackson J, Lee S, Yoo J, Atala A. The effect of substrate elasticity on the function of ovarian follicles [abstract]. Tissue Eng Part A. 2015;21(Suppl 1):S30.

Ju Y, Vossler J, Ahn H, Kim I, Yoo J, Atala A, Lee S. Functional vascular scaffolding system for reconstructing small diameter blood vessels [abstract]. Tissue Eng Part A. 2015;21(Suppl 1):S185.

Ju Y, Vossler JD, Goldstein S, Williams K, Lee S, Yoo JJ, Atala A. Anti-CD133 antibody conjugation to decellularized human heart valves for endothelial progenitor cell capture [abstract]. Tissue Eng Part A. 2015;21(Suppl 1):S140.

Ju Y, Ahn H, Somara S, Baume A, Dean A, Zambon J, Williams K, Allickson J, Yoo J, Atala A, Jackson J. Engineering of corporal tissue constructs using non-human primate/human corpus cavernosum smooth muscle and endothelial cells for clinical applications [abstract]. Tissue Eng Part A. 2015;21(Suppl 1):S207.

Kang HW, Yoo JJ, Atala A. Bioprinted scaffolds for cartilage tissue engineering. Methods Mol Biol. 2015;1340():161-169.

Kengla CV, Kim I, Seol Y, Yoo JJ, Atala A, Lee S. 3-D bioprinting of bone constructs for craniomaxillofacial reconstruction [abstract]. Tissue Eng Part A. 2015;21(Suppl 1):S391.

Ko I, Li P, Pelso A, Smith C, Dhal A, Clouse C, Zhao W, Shupe T, Soker S, Yoo JJ, Atala A. Implantation of re-endothelialized porcine liver constructs for whole organ engineering [abstract]. Tissue Eng Part A. 2015;21(Suppl 1):S85.

Seol Y, Kang H, Lee S, Jackson JD, Skardal A, Shupe T, Soker S, Bishop C, Yoo JJ, Atala A. 3-D bioprinting of tissue organoids for body-on-a-chip drug screening platform [abstract]. Tissue Eng Part A. 2015;21(Suppl 1):S369.

Shi H, Li W, Zhang Y, Clouse C, Sink S, George S, Lue T, Yoo J, Atala A, Jackson J. Restoration of penile erectile function using stem cells in a rat model of neurovascular erectile dysfunction [abstract]. Tissue Eng Part A. 2015;21(Suppl 1):S34-S35.

Skardal A, Devarasetty M, Kang H, Mead I, Bishop C, Shupe T, Lee S, Jackson J, Yoo J, Soker S, Atala A. A hydrogel bioink toolkit for bioprinting tissue constructs while mimicking native tissue biochemical and mechanical properties [abstract]. Tissue Eng Part A. 2015;21(Suppl 1):S212.

Skardal A, Kleensang A, Devarasetty M, Kang H, Mead I, Bishop C, Shupe T, Lee S, Jackson J, Yoo J, Hartung T, Soker S, Atala A. Physiologically relevant drug testing in vitro - an integrated multiple organoid-on-a-chip approach [abstract]. Tissue Eng Part A. 2015;21(Suppl 1):S362.

Wang Z, Cheng H, Seol Y, Yoo JJ, Lee S, Atala A. In vitro evaluations of 3-D bioprinted cardiac tissue constructs [abstract]. Tissue Eng Part A. 2015;21(Suppl 1):S233.

Zambon J, Ko I, Kim I, Smith C, Atala A, Yoo JJ. Bioengineered porcine kidney constructs seeded with autologous cells for long-term survival in vivo [abstract]. Tissue Eng Part A. 2015;21(Suppl 1):S84.

Yoo J. Bioprinting technology as a tool for building complex tissues and organs [abstract]. Tissue Eng Part A. 2015;21(Suppl 1):S9.

Yoo JJ. Cell-based therapies for urogenital tract disorders [abstract]. Tissue Eng Part A. 2015;21(Suppl 1):S35.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Quick Reference

Request an Appointment
New Patients

336-716-WAKE
888-716-WAKE

Existing patients may contact the clinic directly.
Find a Doctor Ways to Give
USNWR 2015-2016Magnet Hospital RecognitionConsumer Choice2015 Best DoctorsJoint Commission Report

Disclaimer: The information on this website is for general informational purposes only and SHOULD NOT be relied upon as a substitute for sound professional medical advice, evaluation or care from your physician or other qualified health care provider.